Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
2. Get
Rid
of
Herpes
Do
you
have
Herpes
Simplex
Virus
Type
2
(Genital
Herpes)?
Are
you
sick
of
hearing
the
following?
• You
will
have
to
live
with
HSV
2
for
the
rest
of
your
life.
• You
can't
ever
get
rid
of
herpes?
• Worse
sAll,
maybe
you
had
a
really
helpful
doctor
like
I
did
that
casually
told
me
that
I
shouldn't
ever
have
sex
again.
FinestHerpesCure.com
3. Get
Rid
of
Herpes
The
Simple
Herpes
Remedy
The
Drug
Companies
Want
to
Keep
Secret
Why…Because
it
can’t
be
patented
or
profited
from.
Most
people
sAll
believe
that
there
is
no
way
to
get
rid
of
herpes.
I
doubted
I
could
ever
stop
my
herpes
outbreaks,
yet
I
did.
In
fact
once
I
knew
how,
it
was
actually
very
straight
forward
not
to
menAon
cheap,
I
only
wished
I
had
known
about
it
a
couple
of
years
ago.
FinestHerpesCure.com
4. Get
Rid
of
Herpes
So
why
hasn't
my
doctor
recommended
this
miraculous
herpes
treatment?.
• First
off
your
Doctor
will
never
prescribe
this
herpes
treatment,
even
though
most
of
them
will
be
well
aware
of
it's
effecAveness,
that
is
unless
you
live
in
Germany
where
the
method
has
remained
in
popular
use
since
the
forAes.
• It's
not
a
licensed
medicaAon,
you'll
be
told
that
there
is
no
medical
evidence
that
it
works.
• It
has
not
been
evaluated
by
the
FDA,
but
nor
has
Green
Tea.
FinestHerpesCure.com
5. Get
Rid
of
Herpes
The
real
reason
you
won't
hear
about
this
simple
herpes
treatment
protocol
boils
down
to
profits.
You
see
the
main
ingredient
can't
be
patented
which
means
the
drug
companies
can't
control
it.
Believe
it
or
not,
If
everyone
suffering
with
herpes
dumped
the
expensive
anAvirals
and
decided
to
treat
their
condiAon
using
this
simple
procedure
the
huge
drug
companies
would
suffer
catastrophic
losses.
FinestHerpesCure.com
6. Get
Rid
of
Herpes
You
may
not
want
to
believe
statements
like
that
&
I
won't
try
to
convince
you
otherwise
but
the
fact
remains
that
this
simple
procedure
has
been
used
for
decades
to
actually
kill
viruses.
So,
do
you
really
want
to
Get
Rid
of
Herpes
&
stop
outbreaks?
Are
you
sick
of
being
told
you’ll
have
to
live
with
herpes
by
uninterested
doctors?
Fed
up
with
taking
expensive
&
ineffecAve
medicaAon…
FinestHerpesCure.com
7. Get
Rid
of
Herpes
Is
genital
herpes
sNll
a
persistent
problem
for
you,
does
it
get
you
down?.
Are
you
sick
and
Nred
of
uninterested
doctors
and
ineffecNve
symptomaNc
treatments?.
If
your
anything
like
I
was,
your
probably
running
out
of
opAons
and
entering
a
state
of
despair,
&
I
completely
understand
how
you
feel,
only
someone
who
has
been
where
you
are
now
can
truly
understand
what
your
going
through
and
that's
why
I
decided
to
publish
my
findings.
FinestHerpesCure.com
8. Get
Rid
of
Herpes
Get
Rid
of
Herpes
details
a
unique
method
of
actually
killing
viral
pathogens
responsible
for
the
herpes
virus
as
well
as
a
quick
and
natural
method
for
healing
herpes
blisters.
This
method
is
suitable
for
both
men
&
woman.
This
is
a
simple
and
powerful
self
treatment
process
which
borrows
it's
formulaAon
directly
from
tried
and
tested,
scienAfic
facts
as
well
as
age
old
remedies.
FinestHerpesCure.com
9. Get
Rid
of
Herpes
Heal
Herpes
Rash
In
Days
&
Stop
Further
Outbreaks:
This
is
a
real
soluAon
to
herpes,
I
know
you've
been
told
Ame
and
Ame
again
that
you
can't
get
rid
of
herpes,
but
that's
just
not
the
case.
You
really
can
stop
outbreaks
using
a
modified
version
of
a
simple
therapy
used
by
thousands
of
European
doctors,
naturopath's,
homeopaths
&
alternaNve
health
pracNNoners.
FinestHerpesCure.com
10. Get
Rid
of
Herpes
This
same,
simple
herpes
protocol
has
been
used
to
treat
the
condiAon
for
decades!
The
only
reason
you
don't
know
about
it
is
because
the
drug
companies
don't
want
you
too.
Healing
herpes
doesn't
have
to
be
complicated
or
expensive,
In
fact
it's
neither.
FinestHerpesCure.com
11. Get
Rid
of
Herpes
You
can
stop
herpes
outbreaks
permanently,
and
furthermore
you
can
do
it
all
quickly,
cheaply
and
from
the
privacy
of
your
own
home.
FinestHerpesCure.com
• No
More
Uninterested
Doctors
• No
More
Expensive
Supplements
• No
More
Embarrassment
• No
More
IneffecAve
Drugs
• No
More
Pointless
Creams
• No
More
Depression
Just
a
life
free
of
herpes
12. Get
Rid
of
Herpes
I
know
your
probably
sNll
scepNcal,
I
know
I
was,
but
the
fact
remains
that
this
is
the
only
method
I
know
of
that
actually
kills
the
cause
of
herpes.
Anyone
who
suffers
with
herpes
and
desperately
wants
to
get
rid
of
it
should
have
access
to
this
method
which
is
why
I'm
guaranteeing
this
informaAon
will
help
you
get
rid
of
herpes.
FinestHerpesCure.com
13. Get
Rid
of
Herpes
Get
Rid
of
Herpes
is
unlike
anything
you
have
ever
seen.
It
show's
you
exactly
how
to
copy
my
simple
method
and
treat
your
own
condiAon
at
home
regardless
of
how
severe
your
herpes
is
right
now.
I
will
tell
you
how
to
accomplish
this
permanent
relief
from
outbreaks
without
any
drugs
whatsoever
(and
that
includes
supplements
&
herbal
herpes
formulaAons).
FinestHerpesCure.com
14. Get
Rid
of
Herpes
Here
are
just
a
few
of
the
amazing
things
you
will
discover:
• What
herpes
really
is,
understand
this
&
you
will
understand
how
it's
possible
to
stop
outbreaks
• Why
lacking
in
one
important
element
leaves
you
at
the
mercy
of
herpes
outbreaks
• An
easy
to
follow
detailed
herpes
relief
protocol
• The
real
reason
this
amazing
herpes
remedy
has
been
deliberately
covered
up
FinestHerpesCure.com
15. Get
Rid
of
Herpes
• Why
this
simple
&
cheap
protocol
is
so
effecAve
against
the
herpes
simplex
virus
• How
this
science
based,
proven
method
allows
your
body
to
kill
the
herpes
virus
• How
to
quickly
get
rid
of
herpes
rash
using
another
amazing
and
cheap
substance
• And
lots
more
FinestHerpesCure.com
16. Find
out
more
about
Get
Rid
of
Herpes
By
clicking
on
the
link
below
Or,
visit
FinestHerpesCure.com