3. Introduction
• The term nutraceuticals is a combination of the word's nutrition and
pharmaceuticals. Nutraceuticals implies that the extract or food which demonstrate
to have a physiological benefit or provide protection against a chronic disease.
Nutraceuticals or functional foods have been found to be associated with the
prevention and/or treatment of many chronic diseases and ailments such as cancer,
diabetes, heart diseases, hypertension, arthritis, osteoporosis etc.
Nutraceutical can be defined as “A food or part of food or
nutrient, that provides health benefits, including the prevention and treatment of a
disease.”
5. Benefits
• Avoid side effects
• Increase the health beneficial effect of any component
• Easily available and economically affordable
• Can cure or prevent any chronic diseases
• Increase the quality of life of human beings
6. Role in Cancer
• Nutraceuticals have ability to control and regulate the DNA damaging
factors in cancer cell and DNA transcription in tumours.
• Chemotherapeutics drugs are derived from vincristine and vinblastine.
• Moderate amounts of high-quality protein, fiber, and omega-3 fatty acid
series are beneficial for cancer patients.
• Phytochemicals protect against lipid peroxidation and modulate innate and
inflammatory responses.
7. • The role of vitamins A, C, E have been suggested to prevent cancer.
• Polyphenols, Epigallocatechin-3-gallate[ green tea ], Resveratrol[ plant
antibiotic ], Quercetin [ flavonoid ] are used to treat cancer.
• Soy food- Breast cancer
• Green tea- Skin cancer
• Grapeseed- UV light induced cancer
• Garlic- Liver cancer
8. Role in CVS
• Sterols/stanols- Consumption of plant sterols/stanols lowers total cholesterol
humans, predominantly LDL-C reduction with little or no effect on high-density
lipoprotein cholesterol (HDL-C) or triglycerides.
• Polyphenols- Polyphenols may influence plasma lipid concentrations. Consumption
of polyphenol has been associated with elevated HDL-C.
• Spirulina- Spirulina[ Spirulina maxima ] supplementation alternates the blood lipid,
associated with significant changes in total cholesterol and LDL-C concentrations.
9. • Tea and its catechin
• Fibrous food like banana, strawberry, barley, etc.
• Annatta- Tocotrienols
• Milk & egg - Pantethine