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NUTRACEUTICAL
 The term Neutraceuticals was coined by
Dr. Stephen De Felice
 Nutraceutical – any substance that is food
or a part of food and provides medical or
health benefits , including the prevention
and treatment of disease.
CARBOHYDRATE
 Carbohydrate is one of the 3 basic macronutrient
It includes sugars, starches and fibers whose major
function is to provide energy for body especially brain and
muscle
The carbohydrate that has nutraceutical applications
include- ascorbic acid, oligosaccharides, non- starch
polysaccharides.
Beneficial health impacts- specific chronic disease such as
cancer, diabetes, CVD, obesity and various gastrointestinal
disorder
1) ASCORBIC ACID
Glucose derivatives- one of the most recognizable
nutraceutical substances and very popular supplement
It functions as an antioxidant
Sources- citrus fruits- orange, kiwi, grapefruit,
brocolli,strawberries
Benefits- necessary for healthy bones, gums, teeth and skin,
helps in wound healing, prevent common cold
It is a powerful antioxidant and free radicle scavenger that
protects our tissue, cell membrane and tissue from oxidative
damage
OLIGOSACCHARIDES AND POLYSACCHARIDES
 Plants produce oligosaccharides that appear to function as
prebiotic substances
 Prebiotic- non digestible food ingredients that benefits the host
by selectively stimulating the growth or activity of 1 or a limited
no. Of bacteria in the colon
 Plant polysaccharides are n readily available energy source for
humans as they are resistant to secreted digestive enzymes
 These grouped with phenolic compounds- lignin to form fibers
has nutraceutical application
 Fibers- play structural role in plants
 Eg- cellulose, hemicellulose
 Role- tissue repair after trauma
Human milk contain
has oligosaccharides
play important role
in postnatal period
0.7-1.2g present
Monomers present
are d-glucose, d-
galactose, N-acetyl
glucosamine,
fructose and sialic
acid
2) NON STARCH POLYSACCHARIDES
Divided into homogenous and heterogenous
polysaccharides
1.cellulose- homologous non starch
polysaccharides-repeating units of glucose
monomers
Present in cell wall of plants as microfibril
bundles
2.hemicellulose - found in association with
celluose in plant cell wall
Composed of pentoses- xylans, mannans,
galactans, arabicans and hexoxes and uronic
acid
 3. chitin- polymer of N- acetyl glucosamine found in shells of insects
 Recently used as dietary supplement for weight loss
 4. Marine polysaccharides- has various health benefits –anticancer , anti-inflammatory, anti-
oxidant, anti-microbial properties
 Eg. Brown, green and red algae
 Decreases plasma total cholesterol and LDL cholesterol
 5.Glycosaminoglycans- found in animal connective tissue
 GAG and chondroitin sulphate used as nutrition supplements for joint injuries and joint
inflammatory disorder
 Components of extracellular substance surrounding collagen and elastin fibres and
connective tissue and bones
 Eg- hyaluronic acid –present in synovial fluid
 Contains- b-glucuronic acid and N-acetyl glucosamine
 Eg- chondroitin sulphate- present in cartilage and bones
 Contains- b-glucuronic acid and N-acetyl galactosamine
FATTY ACIDS AND STRUCTURAL LIPIDS
Present researchers have found various fatty acids have
funtional properties
1. omega- 3 PUFA- found in higher concentration in plants ,
fishes and other marine animals
Fish oil include- EPA,DHA,DPA
SOURCE-fish oils, maize,mustard,linseed, rapeseed, tuna
Benefits- reduce CVD and improve mental and visual function,
reduce inflammatory and immunological disease
Plants use this as second messenger to form jasmonic acid
when plant tissue is under attack-insect feeding
2. CONJUGATED LINOLEIC ACID(CLA)
It is produced by bacteria
Source- cheese, meat,milk,butter, yogurt
Benefits- improves body composition and reduce
cancers, anti carcinogenic effect , decrease the LDL in
rabbit and decrease artherosclerosis lesions
For dairy products the CLA- 30mg/g of fat
Food processing methods like frying, baking, boiling
did not affect or change CLA content
classification of nutraceuticals based on their chemical nature

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classification of nutraceuticals based on their chemical nature

  • 1.
  • 2. NUTRACEUTICAL  The term Neutraceuticals was coined by Dr. Stephen De Felice  Nutraceutical – any substance that is food or a part of food and provides medical or health benefits , including the prevention and treatment of disease.
  • 3. CARBOHYDRATE  Carbohydrate is one of the 3 basic macronutrient It includes sugars, starches and fibers whose major function is to provide energy for body especially brain and muscle The carbohydrate that has nutraceutical applications include- ascorbic acid, oligosaccharides, non- starch polysaccharides. Beneficial health impacts- specific chronic disease such as cancer, diabetes, CVD, obesity and various gastrointestinal disorder
  • 4. 1) ASCORBIC ACID Glucose derivatives- one of the most recognizable nutraceutical substances and very popular supplement It functions as an antioxidant Sources- citrus fruits- orange, kiwi, grapefruit, brocolli,strawberries Benefits- necessary for healthy bones, gums, teeth and skin, helps in wound healing, prevent common cold It is a powerful antioxidant and free radicle scavenger that protects our tissue, cell membrane and tissue from oxidative damage
  • 5. OLIGOSACCHARIDES AND POLYSACCHARIDES  Plants produce oligosaccharides that appear to function as prebiotic substances  Prebiotic- non digestible food ingredients that benefits the host by selectively stimulating the growth or activity of 1 or a limited no. Of bacteria in the colon  Plant polysaccharides are n readily available energy source for humans as they are resistant to secreted digestive enzymes  These grouped with phenolic compounds- lignin to form fibers has nutraceutical application  Fibers- play structural role in plants  Eg- cellulose, hemicellulose  Role- tissue repair after trauma Human milk contain has oligosaccharides play important role in postnatal period 0.7-1.2g present Monomers present are d-glucose, d- galactose, N-acetyl glucosamine, fructose and sialic acid
  • 6. 2) NON STARCH POLYSACCHARIDES Divided into homogenous and heterogenous polysaccharides 1.cellulose- homologous non starch polysaccharides-repeating units of glucose monomers Present in cell wall of plants as microfibril bundles 2.hemicellulose - found in association with celluose in plant cell wall Composed of pentoses- xylans, mannans, galactans, arabicans and hexoxes and uronic acid
  • 7.  3. chitin- polymer of N- acetyl glucosamine found in shells of insects  Recently used as dietary supplement for weight loss  4. Marine polysaccharides- has various health benefits –anticancer , anti-inflammatory, anti- oxidant, anti-microbial properties  Eg. Brown, green and red algae  Decreases plasma total cholesterol and LDL cholesterol  5.Glycosaminoglycans- found in animal connective tissue  GAG and chondroitin sulphate used as nutrition supplements for joint injuries and joint inflammatory disorder  Components of extracellular substance surrounding collagen and elastin fibres and connective tissue and bones  Eg- hyaluronic acid –present in synovial fluid  Contains- b-glucuronic acid and N-acetyl glucosamine  Eg- chondroitin sulphate- present in cartilage and bones  Contains- b-glucuronic acid and N-acetyl galactosamine
  • 8. FATTY ACIDS AND STRUCTURAL LIPIDS Present researchers have found various fatty acids have funtional properties 1. omega- 3 PUFA- found in higher concentration in plants , fishes and other marine animals Fish oil include- EPA,DHA,DPA SOURCE-fish oils, maize,mustard,linseed, rapeseed, tuna Benefits- reduce CVD and improve mental and visual function, reduce inflammatory and immunological disease Plants use this as second messenger to form jasmonic acid when plant tissue is under attack-insect feeding
  • 9. 2. CONJUGATED LINOLEIC ACID(CLA) It is produced by bacteria Source- cheese, meat,milk,butter, yogurt Benefits- improves body composition and reduce cancers, anti carcinogenic effect , decrease the LDL in rabbit and decrease artherosclerosis lesions For dairy products the CLA- 30mg/g of fat Food processing methods like frying, baking, boiling did not affect or change CLA content