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Prepared By
Magferatun Nessa MiLii
Product Manager, PMD
1
Indication
Heartburn,
Indigestion,
GERD &
Others Hyperacidity related complications.
Many People think that INDIGESTION and
HEARTBURN are the same but quite often HEARTBURN
is one of the symptoms of INDIGESTION.
2
Magferatun Nessa MiLii, PMD
Mechanism of Action
is the combination of two antacids (Calcium Carbonate
& Sodium Bicarbonate) & an Alginate (Sodium Alginate).
Gavonix work in two ways-
1. Neutralizing excess stomach acid to relieve the pain &
discomfort.
2. Forming protective barrier over stomach contents to soothe the
burning pain in chest.
3
Magferatun Nessa MiLii, PMD
Mechanism of Action
is a unique combination of –
4
Sodium Alginate
• Reacts with acid to form a viscous layer of Alginate, on top of
the stomach content, which exerts anti-reflux action.
Sodium Bicarbonate
• Neutralizes gastric acid & forms Carbon dioxide, which gets trapped
into the viscous gel of Alginate & floats it to the surface of stomach
content.
Calcium Carbonate
• Neutralizes gastric acid & links with Alginate to strengthen protective
raft or barrier on top of the stomach contents, which ensures
stronger & prolong effect.
World Gastroenterology Organisation (WGO) &
National Institute for Health and Care Excellence (NICE)
First Line Treatment
for GERD Symptoms
management
If symptoms
persist
Alginate Antacid
(Gavonix) + Proton
Pump Inhibitor(PPI)
Optimal Relief
5
Magferatun Nessa MiLii, PMD
Dosage And Administration
For Oral Administration
Adults & Children Over 12 Years:
10-20ml after meals and at bedtime, up to four times a day.
Children 6 to 12 Years:
05-10ml after meals and at bedtime, up to four times a day.
Children under 6 years: Not recommended.
Elderly: No dosage modification is required for this age group.
6
Magferatun Nessa MiLii, PMD
Pregnancy & Lactation
Pregnancy:
This product can be used during
pregnancy.
Lactation:
This product can be used during
breast-feeding.
7
Magferatun Nessa MiLii, PMD
Key Message
Best Combination for GERD & Indigestion.
Fastest Onset of action within 3 minutes.
Provides long lasting effect up to 4 hours.
Works physically in non-systemic mode of action.
Doesn’t show Acid Rebound effect.
Directly targets the Acid Pocket.
Can be given from 6 years old.
Can also be Co-administered with PPIs.
Safe in Pregnancy & Lactation.
Suitable for Diabetic & Obese Patient.
Free from side-effects like Constipation & Diarrhea.
Doesn’t interfere the nutritional value of food.
Mint Oil exerts Cooling & Soothing Effect just after taken. 8
9
GAVONIX (Calcium Carbonate, Sodium Bicarbonate, Sodium Alginate)

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GAVONIX (Calcium Carbonate, Sodium Bicarbonate, Sodium Alginate)

  • 1. Prepared By Magferatun Nessa MiLii Product Manager, PMD 1
  • 2. Indication Heartburn, Indigestion, GERD & Others Hyperacidity related complications. Many People think that INDIGESTION and HEARTBURN are the same but quite often HEARTBURN is one of the symptoms of INDIGESTION. 2 Magferatun Nessa MiLii, PMD
  • 3. Mechanism of Action is the combination of two antacids (Calcium Carbonate & Sodium Bicarbonate) & an Alginate (Sodium Alginate). Gavonix work in two ways- 1. Neutralizing excess stomach acid to relieve the pain & discomfort. 2. Forming protective barrier over stomach contents to soothe the burning pain in chest. 3 Magferatun Nessa MiLii, PMD
  • 4. Mechanism of Action is a unique combination of – 4 Sodium Alginate • Reacts with acid to form a viscous layer of Alginate, on top of the stomach content, which exerts anti-reflux action. Sodium Bicarbonate • Neutralizes gastric acid & forms Carbon dioxide, which gets trapped into the viscous gel of Alginate & floats it to the surface of stomach content. Calcium Carbonate • Neutralizes gastric acid & links with Alginate to strengthen protective raft or barrier on top of the stomach contents, which ensures stronger & prolong effect.
  • 5. World Gastroenterology Organisation (WGO) & National Institute for Health and Care Excellence (NICE) First Line Treatment for GERD Symptoms management If symptoms persist Alginate Antacid (Gavonix) + Proton Pump Inhibitor(PPI) Optimal Relief 5 Magferatun Nessa MiLii, PMD
  • 6. Dosage And Administration For Oral Administration Adults & Children Over 12 Years: 10-20ml after meals and at bedtime, up to four times a day. Children 6 to 12 Years: 05-10ml after meals and at bedtime, up to four times a day. Children under 6 years: Not recommended. Elderly: No dosage modification is required for this age group. 6 Magferatun Nessa MiLii, PMD
  • 7. Pregnancy & Lactation Pregnancy: This product can be used during pregnancy. Lactation: This product can be used during breast-feeding. 7 Magferatun Nessa MiLii, PMD
  • 8. Key Message Best Combination for GERD & Indigestion. Fastest Onset of action within 3 minutes. Provides long lasting effect up to 4 hours. Works physically in non-systemic mode of action. Doesn’t show Acid Rebound effect. Directly targets the Acid Pocket. Can be given from 6 years old. Can also be Co-administered with PPIs. Safe in Pregnancy & Lactation. Suitable for Diabetic & Obese Patient. Free from side-effects like Constipation & Diarrhea. Doesn’t interfere the nutritional value of food. Mint Oil exerts Cooling & Soothing Effect just after taken. 8
  • 9. 9