Bisacodyl is a contact laxative that acts directly on the colonic mucosa to stimulate peristalsis. It is poorly absorbed and usually produces a bowel movement 6 hours after oral administration or 15 minutes to 1 hour after rectal administration. Bisacodyl is useful for treating various types of constipation and can be used as a bowel cleanser prior to procedures. Common side effects include stomach pain, cramping, nausea, diarrhea, or weakness.

1. Bisacodyl (diphenylmethane derivative)
Enteric coated tablets: 5 mg Bisacodyl.
Suppository : 5 mg , 10 mg Bisacodyl.

2. Bisacodyl is a contact stimulant laxative
Act directly on the colonic mucosa to produce normal peristalsis.
Very poorly absorbed
Bilaxine is useful in all kinds of constipation :
Chronic constipation in aged patient
Patients with constipation resulting from prolonged bed-lying
Pre and post surgical operation
Preparation for barium enema
Preparation of colon and procot-sigmoid scopy

3. On contact with the mucosa or submucosal plexus of the large
intestine, Bisacodyl stimulates sensory nerve endings to produce
parasympathetic reflexes, resulting in increased peristaltic
contraction of the colon.
It has also been shown to promote fluid and ions accumulation in
the colon , which increases the laxitive effect.
Bowel movment is usually produced approximately 6 hours after
oral administration and approximately 15 minutes to 1 hour after
rectal administration , providing satisfactory cleansing of the bowel
which may , under certain circumstances , obviate the need for
colonic irrigation .

4. For patients with acute surgical abdomen , appendicitis , rectal
bleeding , gastroenteritis , or intestinal obstruction .
. Do not crush, chew, or break the tablet or take it within 1 hour of
antacids, milk, or milk products.
Do not take this medication for more than 7 days unless directed by
your doctor , it should not given to children under 6 years .
It may take 6 to 12 hours before this medication causes a bowel
movement.

5. Category B , no teratogenic effects have been detected in animals or
human infants , manufactures recommended that bisacodyl should not
be used at the first trimester , unless the expected benefit is thought
to outwight any possible risk to the fetus .
Stomach/abdominal pain or cramping, nausea, diarrhea, or weakness
may occur.

6. Adult and children 12 years of age and over “
2 tablet at bed time in order for an effect in the next morning
Or halve hour before breakfast for an effect after 5 hours .
Dose may increase to 4 tablets if necessary .
OR 1 suppository 10mg once daily , remove foil wrapper . Lie on
your side and , with pointed end first , push suppository into the
rectume so it will not slip out .

7. Some products that may interact with this drug include: medications
that decrease stomach acid (such as H2 blockers like ranitidine,
proton pump inhibitors like omeprazole).This document does not
contain all possible interactions.
4 years , keep in cool and dry place .