Gallstones form when substances in bile harden into solid pieces in the gallbladder. There are two main types of gallstones: cholesterol stones and pigment stones. Risk factors for developing gallstones include genetics, being overweight, gallbladder problems, and diet. Common symptoms are nausea, vomiting, indigestion, and pain in the upper abdomen or right shoulder. Diagnosis involves ultrasound, CT scans, or other imaging tests. Treatment options are surgery to remove the gallbladder or, sometimes, medications to dissolve gallstones.