This document discusses connecting magic and science through various projects and demonstrations. It introduces Miquel Duran, a professor who promotes using magic to explain complex chemistry concepts. Some of his projects include using magic to explain topics like aromaticity, entropy, and the periodic table. The document discusses how magic can engage students and improve communication skills, while science can create new magical effects. It provides examples of using magic to explain the periodic table and elements at an event.
IYC2011: Magic, a catalyst for Science awarenessMiquel Duran
IYC2011 has been a great opportunity to innovate ways to foster science in general and chemistry in particular. Our team, who is involved in amateur magic, has adapted classical games to IYC characteristics. For instance, we have adapted many games based on mathematical properties to the periodic table, or we have used Chemical cards (each containing an atomic symbol) instead of usual Poker cards.
Everyone knows why libraries matter. And yet, some people are questioning our role and value in the 21st century. How do we share the excitement for how libraries are evolving and innovating as a community institution? In this keynote, you’ll learn storytelling strategies specific to the unique opportunities and challenges faced by libraries today. For the last year, our presenter, Michael Margolis, CEO of Get Storied, has collaborated closely with both the California and Pennsylvania State Libraries around this issue. Come learn why it’s important to tell your story, how to do it right, and some simple ways to get storied. Your story matters.
Digital pathology 2018 | Aug 13-14 | Madrid, SpainAyush Lawania
EuroScicon Ltd is glad to invite all the experts in the arena of Pathology to its premier 3rd International Conference on Digital Pathology (Digital Pathology-2018), which is going to be held at Madrid, Spain during August 13-14, 2018. The Theme of the conference is “Digital Pathology Image Analysis: Advancements, Opportunities and Challenges for 21st Century.”
Digital Pathology-2018 brings together the pathologists from both Industry and academia to discuss the advancements and challenges in the broad sector of Pathology but not limited to Molecular Pathology, Cytopathology, Histopathology, Clinical Pathology, Breast Pathology, Immunopathology, Cancer Pathology, Gynaecological pathology, Forensic Pathology, Chemical Pathology and all other allied fields.
So come and be a part of the Europe’s best conference.
IYC2011: Magic, a catalyst for Science awarenessMiquel Duran
IYC2011 has been a great opportunity to innovate ways to foster science in general and chemistry in particular. Our team, who is involved in amateur magic, has adapted classical games to IYC characteristics. For instance, we have adapted many games based on mathematical properties to the periodic table, or we have used Chemical cards (each containing an atomic symbol) instead of usual Poker cards.
Everyone knows why libraries matter. And yet, some people are questioning our role and value in the 21st century. How do we share the excitement for how libraries are evolving and innovating as a community institution? In this keynote, you’ll learn storytelling strategies specific to the unique opportunities and challenges faced by libraries today. For the last year, our presenter, Michael Margolis, CEO of Get Storied, has collaborated closely with both the California and Pennsylvania State Libraries around this issue. Come learn why it’s important to tell your story, how to do it right, and some simple ways to get storied. Your story matters.
Digital pathology 2018 | Aug 13-14 | Madrid, SpainAyush Lawania
EuroScicon Ltd is glad to invite all the experts in the arena of Pathology to its premier 3rd International Conference on Digital Pathology (Digital Pathology-2018), which is going to be held at Madrid, Spain during August 13-14, 2018. The Theme of the conference is “Digital Pathology Image Analysis: Advancements, Opportunities and Challenges for 21st Century.”
Digital Pathology-2018 brings together the pathologists from both Industry and academia to discuss the advancements and challenges in the broad sector of Pathology but not limited to Molecular Pathology, Cytopathology, Histopathology, Clinical Pathology, Breast Pathology, Immunopathology, Cancer Pathology, Gynaecological pathology, Forensic Pathology, Chemical Pathology and all other allied fields.
So come and be a part of the Europe’s best conference.
Similar to From the Magic of Science to the Science of Magic (20)
Comunicació Científica i Postveritat PositivaMiquel Duran
Presentació PPT tipus PechaKucha 20x30 (10 minuts) per acompanyar la xerrada-joc de Miquel Duran i Sílvia Simon, jornada FCRi al Cosmocaixa BCN 12/4/2018
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
1. From the Magic of Chemistry
to the Chemistry of Magic
#magsci
#nosic8, Prullans, 7/6/2018
Miquel Duran @miquelduran
Institut de Química Computacional i Catàlisi
Càtedra de Cultura Científica i Comunicació Digital
Universitat de Girona
Project co-leader in Madrid @fblascoxyz
Current Girona team @judit__torrent @silviasimonr @pepduran
3. Let’s start with an enticing song!
https://www.youtube.com/watch?v=ljsUVDOc
YB0
4. Micro + mini CV
Miquel Duran (@miquelduran aka @quelet)
is professor of Physical Chemistry at the
University of Girona and a researcher in
Quantum Chemistry.
Fostering Internet tools in science
communication, a few years ago a short
course in magic opened him an amazing
world to connect Magic and Science.
He promotes actively Open Knowledge, is
friends with MOOCs, organizes TEDxUdG
events - and rides an MTB in his leisure time.
His preferred quote belongs to "Le Petit
Prince": "Tu sais, quand on est tellement
triste, on aime les couchers de soleil". And
his own “This is me and my digital
circumstances.
Website: http://miquelduran.net
University professor.
Research in Quantum
Chemistry.
Digital Science
Communication,
Magic and Science,
MOOCs,
TEDx events,
Open Knowledge
@miquelduran
Wikipedia
usuari:quelet
5. What is a magician?
• An artist that plays the role of a magician (classic
definition)
• A university professor that plays (or does not play a
all) the role of a university professor (quantum
definition)
7. We like to comunicate science using low-
cost procedures in terms of time, energy,
money, ... And attention
• And we love to explain complex concepts in Science
(and Chemistry indeed) using metaphors,
analoges... And Magic of course
• Examples:
• Aromaticity
• Entropy
• Quantum mechanics
• EPR entangled pairs
• DNA (structure, mutations), proteins
8. Academic projects
• We think that dissemination/science
communication projects, and also education
innovation projectes, should be similar to hard-
research projects: 3 year, competitive, peer-
reviewed, assessed.
• They should give rise to salary rewards and taken
into account in hiring/promotion processes.
9. On Open Knowledge
• We advocate the use of Open Knowledge, Open
Science
• We foster good communication skills by our Ph.D.
students – and all members of the Department of
Chemistry.
• We try to make intelligent use of Internet tools.
10. Clues
• 2015 and 2017 meetings on Science, Magic, and
Education
• 2016, 2017 and 2018 Summer Camp on Magic and
Science, targeted to high schollers and early science
students.
• TEDxUdG and TEDxGironaWomen series of events
11. Magic and Science: the project
• Magic of the Periodic Table (2015)
• Magic of Food (2016)
• Magic of Color (2017)
• WeekDayRings (2017)
• Magic of Rubik’s Cube (2018)
• Magic of the Periodic Table revisited (2019, UNESCO IY)
• Collaboration with Dr. Fernando Blasco, Univ Polit
Madrid, maths professor and mathemagician.
12. Magic and Science?
• Magic useful to understand, engage with, and
promote awareness of, Science.
• Science explains Magic – and provides new effects
and creates new tools.
• Magic allows to improve Communication Skills
• Magic increases self-confidence: against fear of
rejection and fear of failure
• Secrets, Mysteries, and awe
13. A relevant note here:
• Let’s perform games and tricks where the
secret, if ever revealed, leads to a better
experience that attending the magic
performance itself
• That’s what mathematics-based tricks are!
50. About your favourite Chemist
• A nice game where your favourite Chemist will help
us find a card freely selected by you.
• A classical Martin Gardner mathematics-based
trick.
[spelling]
51. Looking forward...
• UNESCO International Year of the Periodic Table of
the Elements 2019
• Tetris
• 3-D PTE with cubes, tetris-like
• Connection between PTE and the Rubik’s Cube
analog Pyraminx
• More adaptations and new magical tricks involving
the Table and the Elements