This article reviews literature on fracture of dental implants and presents a case report. It finds that implant fracture is a rare but severe complication with multiple potential contributing factors. These include design flaws, poor fit of superstructures, excessive occlusal forces, location in high stress areas like the posterior mandible, small implant diameter, metal fatigue, and bone resorption around implants. The case report describes a titanium implant that fractured after 4 years due to metal fatigue, which was potentially caused by bone loss facilitated by leakage of toxic nickel ions from the implant's non-precious metal crown. This suggests corrosion and ion leakage should be considered a possible risk for late implant fractures.
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Biomechanics of dental implants/certified fixed orthodontic courses by Indian...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
loading protocols in dental implants about indications and contraindications of conventional , immediate,progressive and delayed loading of dental implants
Loading of implants /certified fixed orthodontic courses by Indian dental aca...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Immediate loading of implant supported over dentures using / dental implant c...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Biomechanics of dental implants/certified fixed orthodontic courses by Indian...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
loading protocols in dental implants about indications and contraindications of conventional , immediate,progressive and delayed loading of dental implants
Loading of implants /certified fixed orthodontic courses by Indian dental aca...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Immediate loading of implant supported over dentures using / dental implant c...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
Indian Dental Academy: will be one of the most relevant and exciting
training center with best faculty and flexible training programs
for dental professionals who wish to advance in their dental
practice,Offers certified courses in Dental
implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic
Dentistry, Periodontics and General Dentistry.
Implant Loading Protocols Journal Club-Comparative evaluation of the influenc...Partha Sarathi Adhya
This journal club deals with different loading protocols and comparative analysis among them. this basically deals with immediate and delayed loading protocols.
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
Micro implant anchorage in orthodontics /certified fixed orthodontic courses ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Implant design and consideration /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
implantology biologic and clinical aspects / academy of fixed orthodonticsIndian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
occlusal considerations for Implant supported Prosthesis /certified fixed or...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
classification, Type of Fixtures Sterilization and Passivation/endodontic cou...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Indian Dental Academy: will be one of the most relevant and exciting
training center with best faculty and flexible training programs
for dental professionals who wish to advance in their dental
practice,Offers certified courses in Dental
implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic
Dentistry, Periodontics and General Dentistry.
Implant Loading Protocols Journal Club-Comparative evaluation of the influenc...Partha Sarathi Adhya
This journal club deals with different loading protocols and comparative analysis among them. this basically deals with immediate and delayed loading protocols.
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
Micro implant anchorage in orthodontics /certified fixed orthodontic courses ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Implant design and consideration /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
implantology biologic and clinical aspects / academy of fixed orthodonticsIndian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Indian Dental Academy: will be one of the most relevant and exciting training
center with best faculty and flexible training programs for dental
professionals who wish to advance in their dental practice,Offers certified
courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry,
Prosthetic Dentistry, Periodontics and General Dentistry.
occlusal considerations for Implant supported Prosthesis /certified fixed or...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
classification, Type of Fixtures Sterilization and Passivation/endodontic cou...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
loading of dental implants/certified fixed orthodontic courses by Indian dent...Indian dental academy
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
differences between natural tooth periodontium and implant bone connection, biomechanics of implants, implant protected occlusion , occlusal principles for single tooth implant prosthetics and implant supported prosthesis on edentulous arch, shortened arch concept, therapeutic occlusion
Immediate Implant Placement And Restoration With Natural Tooth In The Maxilla...Abu-Hussein Muhamad
Anterior tooth loss and restoration in the esthetic zone is a common challenge in dentistry today. The prominent visibility of the area can be especially distressing to the patient and requires a timely and esthetically pleasing solution. Immediate single-tooth implantation followed by immediate provisionalization is becoming an increasingly desirable treatment that offers numerous benefits over conventional delayed loading. Provisionalization for immediately-placed implants using the patient’s existing tooth can enhance the final aesthetic outcome if certain steps are
followed. If the natural tooth is intact and can be used as a provisional, the emergence profile can be very similar to the preoperative condition. This article outlines a technique to use the patient’s natural tooth after extraction to provisionalize an implant.
Stress & force factors in implants /certified fixed orthodontic courses by I...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Stress & force factors /certified fixed orthodontic courses by Indian dental ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Short Implants and their role in prosthetic replacement of missing toothSivaRaman Sms
This is an seminar on short implants related to implant dentistry .
This gives the insight on what has happened since the evolution of short implants and its role in implantology .Their role as replacement of missing tooth in the atrophied maxillary and mandibular posterior regions
Stress & force factors/cosmetic dentistry course by Indian dental academyIndian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. ranged in a straight line. This
geometry allows for bending to
occur as a result of lateral occlu-
sal components, which might
lead to an implant’s fracture.18
b. Leverage—the forces generated
at the occlusal contact position
may be magnified to a consider-
able degree at the implant cross
section with the alveolar crest.
This phenomenon may occur if
there is a lever arm between the
position of forced contact and
the position of support.18–20
4. Bruxism or heavy occlusal
forces. A parafunctional occlusal
habit can contribute to the potential
overload, as load magnitude, dura-
tion, frequency, and direction are
increased by such activity. Exces-
sive wear and a history of fractur-
ing natural teeth or veneering ma-
terial are considered signs of
excessive functional load.13,18
5. Design of the superstructure. The
type of restoration may influence
the load and stress that are trans-
mitted to the implant. An implant
supporting a bridge, for example,
has a smaller tendency to fracture
than an implant supporting a re-
movable prosthesis.6
Cantilever
type bridges tend to break more
often than “conventionally” de-
signed bridges.21,22
6. Implant location. Piattelli et al23
have claimed that implants at the
posterior mandible are most prone
to fracture. In a different study,13
he
found that maxillary implants have
a higher predisposition to fracture.
Rangert et al18
showed that im-
plants located in posterior regions
were at an increased risk of over-
load. A multicenter analysis of ITI
implants (ITI; Straumann AG,
Waldenburg, Switzerland) used for
single tooth replacements1
also re-
vealed fractures only in the molar
region, predominantly in the man-
dibular first molar area. In this
area, load level is high, and the
buccolingual jaw movement and
cusp orientation generate excessive
laterally-directed forces. In their
study, all single tooth fractures oc-
curred in the posterior mandible. In
all, 90% of the fractures involved
the first premolar region or further
posteriorly. In a study of 353 pa-
tients,4
all restored with fixed res-
torations, only three patients expe-
rienced implant fracture, all of
them in the mandible.
7. Implant size (diameter). Small-
diameter implants tend to fracture
more easily than large ones, espe-
cially when placed in a posterior
location. According to Siddiqui
and Caudill,14
an implant 5 mm in
diameter is three times stronger
than a 3.75-mm implant, and an
implant 6 mm in diameter is six
times stronger than a 3.75-mm im-
plant. Another advantage of the
wider implant is that they are more
biomechanically appropriate for re-
placing larger posterior teeth.
8. Metal fatigue. According to Mor-
gan et al25
and Linkow et al,27
most
fractures during loading were due
to metal fatigue and not overload.
The high local stresses required for
crack initiation and propagation are
thought to be the result of three
conditions:
• Periimplant bone resorption—this
leads to higher bending stresses
(see below).
• Cross-sectional changes in the
implant—when bone loss reaches
a level corresponding to the end
of the abutment screw, the im-
plant is converted from a solid
composite cylinder to a tube
(without the central screw). Con-
sequently the resistance to bend-
ing is reduced in this region and
bending and axial stresses be-
come much greater.
• Stress concentration—the sharp
corner of the root of a thread cre-
ates an area of significant stress
concentration, providing an ideal
site for crack initiation. The
cracks that propagate from the
site of maximum stress may result
in sudden failure.13
9. Bone resorption around the im-
plant. In many cases, such resorp-
tion was found preceding implant
fracture, particularly when single
molar implants were involved.
Corono-apical bone resorption pro-
duces a higher bending stress on
the implant, because of the loss of
supporting bone. Furthermore, this
periimplant bone resorption usually
extends to the level corresponding
to the end of the abutment screw
where the resistance to bending is
diminished.18,25
The behavior of
periimplant bone is tightly related
to the magnitude and direction of
stresses that are transmitted to the
implant. These forces are affected
by the nature of the opposite den-
tition, bite force, number of im-
plants available to carry the load,
position of the implant within the
prosthesis, and implant geometry.26
REPORT OF A CASE
Clinical Data
A 78-year-old female, with a par-
tially edentulous mandible, was re-
ferred for implant treatment. Her med-
ical history was of no consequence.
A 12-mm hollow-cylindrical
transgingival implant (ITI) was in-
serted in the lower left second premo-
lar area. Implants were not inserted in
the molar area, due to the lack of ver-
tical bone height. After a three-month
preloading healing period with no
complications noted, clinical os-
seointegration was achieved, and the
patient was sent back to the referring
dentist for restoration. A ceramic
fused-to-metal crown was fabricated
and permanently cemented (Fig. 1).
The patient received maintenance
therapy on an irregular basis—approx-
imately once per year. Radiograph
follow-up revealed mild resorption
around the implant. No clinical symp-
toms were evident at that time (Fig. 2).
Four years after implant place-
ment, the patient presented at the of-
fice complaining of discomfort on the
left side of her lower jaw with loosen-
ing of the crown. Clinical examination
revealed excessive horizontal move-
ment of the crown and swelling in the
adjacent mucosa. The crown was re-
moved using a very light force and
came off together with the upper third
of the implant (Fig. 3). Radiographs
taken at that time revealed the apical
part of the osseointegrated implant
with broken edges and noticeable bone
loss, coronal to the implant’s broken
edge. The patient elected not to re-
move the apical portion of the implant,
which was left to heal subgingivally.
A year later, new bone was evident
around the apical portion of the im-
plant (Fig. 4). The soft tissue had
138 FRACTURE OF DENTAL IMPLANTS
3. healed and the edentulous ridge was
restored with a removable prosthesis.
Metallurgic Analysis
The broken implant and the crown
were sent for metallurgic analysis. The
following analyses were performed:
energy dispersive spectroscopy of the
implant and the crown, fractography,
and prosthetic analysis.
Energy dispersive spectroscopy
revealed that the implant was made of
pure titanium, and the crown of
nickel-chromium-molybdenum alloy.
Fractography, at low magnification,
showed that the implant was hollow at
this level (Fig. 5A); and at high mag-
nification, striations indicated brittle
fractures (Fig. 5B). The latter occurs
following metal fatigue caused by cy-
clic loading, such as chewing.16
The
prosthetic analysis revealed corrosion
on the surface of the crown. The lab-
oratory analysis suggested that toxic
nickel ions from the crown’s infra-
structure might have diffused into the
periimplant tissue, contributing to
bone resorption.
DISCUSSION
In the case report presented here,
a previously osseointegrated implant
fractured 4 years after placement. This
kind of fracture can be defined as a
late failure,2
the etiology of which may
be multifactorial. From a biological
point of view, periimplantitis that de-
velops around the implant may result
in bone resorption, which may lead to
a consequent fracture. The mechanism
of such bone resorption is well docu-
mented.28–31
Periimplantitis may range
from localized mucositis to a more
advanced lesion, where bone loss
around a previously osseointegrated
oral implant results in “disintegra-
tion.”29
This lesion is the result of an
inflammatory response to plaque accu-
mulation and may show progression
similar to that observed around natural
teeth. Mucositis is a prerequisite for
the development of periimplantitis,
but the factors involved in the transi-
tion from an initial to an advanced
lesion are not fully understood.30
The
microbial flora in periimplantitis is
characterized by a large number of
gram-negative pathogens and spiro-
chetes.32
The bacteria in the partially
edentulous implant case may be more
pathogenic than in the fully edentulous
case, indicating a possible seeding
mechanism from tooth pocket to im-
plant crevice.33
Leakage of cytotoxic metal ions
into the periimplant tissue may be an-
other factor to facilitate bone resorp-
tion. Different types of nonprecious
alloys may discharge toxic ions, usu-
ally nickel or chromium that diffuse
Fig. 1. Panoramic radiograph of the os-
seointegrated implant with the prosthetic res-
toration.
Fig. 2. Panoramic radiograph 1 year after
loading. Note initial bone resorption around
the implant’s neck (arrows).
Fig. 3. Coronal fragment of the implant with the crown.
Fig. 4. Panoramic radiograph 1 year after extraction of the fractured coronal portion. Complete
bone healing.
Fig. 5. Scanning electron microscopy views
of the fracture. A, Low power view of the
fractured surface of the HC-Titanium im-
plant: magnification ϫ20, bar ϭ 1 mm. The
fractured surface exhibits a dimpled as-
pect, characteristic of tensile fracture. Note
that at the site of the fracture, the implant
appears as a ring, because it is hollow at
this level. B, Higher magnification of the
surface of the fracture: magnification
ϫ2200, bar ϭ 10 mm. The symmetrical
parallel striations (arrow) are indicative of
brittle fractures.
IMPLANT DENTISTRY / VOLUME 11, NUMBER 2 2002 139
4. into the periimplant tissue and
cause tissue reaction and bone resorp-
tion.24
Most implant systems are made
of commercially pure titanium. There-
fore, only the superstructure (crown or
bridge) may be the source of these
ions, especially when made of nonpre-
cious or semi-precious alloys, such as
nickel-chromium-molybdenum. Cor-
rosion may set in and result in the
leaking of ions into the surrounding
tissues. Clinical signs and symptoms
of this local toxic reaction include dis-
coloration, swelling, bleeding, and
infection.34
Corrosion of the metal crown may
be caused or accelerated by differ-
ences in the electric potential between
the implant (made of pure titanium)
and the crown (made of nickel-
chromium-molybdenum alloy). Tita-
nium is a highly reactive metal, con-
trary to common belief. It is cathodic
to most metals and when coupled to-
gether, may accelerate galvanic attack
on the less noble ones. The parameters
that affect the magnitude of this gal-
vanic corrosion are the difference in
the electrolytic potential between the
metals and the contact area between
the metals. The electrolytic potential
of a given metal is a constant. The
difference can be minimized by fabri-
cating the restoration from a metal al-
loy that possesses a similar, or close,
electrolytic potential to that of tita-
nium. Alternatively, the contact area
between the implant and the restora-
tion may be isolated by the use of
cement (such as zinc phosphate ce-
ment).35
Reducing the relative contact
area between the two metals is not
recommended, as it will reduce the
retention of the restoration.36
There-
fore, the possibility of galvanic corro-
sion must always be kept in mind
when choosing a metallic alloy for the
crown.
In a series of 22 failed implants,
which were analyzed by scanning
electron microscope and Auger elec-
tron spectroscope, Esposito et al37,38
found only one case of clinical infec-
tion. The surface of the implant re-
trieved from the infected site consisted
of titanium oxide and varying amounts
of additional elements, predominantly
carbon. Nitrogen, sodium, calcium,
phosphorus, chlorine, sulfur, and sili-
con were detected. The effect of these
materials on the implant-bone inter-
face is unknown, but they may be in-
volved in the failure of the implant.
Additionally, it is known that nickel
ions, corroded from nonprecious met-
als, may cause tissue necrosis, bone
loss, impaired bone mineralization,
and even loosening of orthopedic im-
plants.39
Nickel ions are toxic to os-
teogenic cells and they affect their
proliferation and differentiation. Fi-
nally, it was recently recommended to
limit the use of nickel in the oral
cavity.40
We would like to suggest taking
the following factors into consider-
ation—the possible mechanisms that
led to the fracture represented here.
High cyclic load caused breakdown
and washout of the cement, and pos-
sibly some bone resorption around the
implant. Exposure of the different
metals to saliva caused galvanic cor-
rosion of the crown, followed by re-
lease and diffusion of nickel ions into
the surrounding bone. At that stage,
bone resorption, related to plaque-
induced periimplantitis and nickel
ions’ toxic effect, was accelerated, and
the torque produced on the implant
increased concurrently, fueling the re-
sorptive process. This, in turn, contrib-
uted to increased mobility of the im-
plant that accelerated and eventually
led to fracture of the implant.
CONCLUSIONS
This case report illustrates a pos-
sible adverse affect of nonprecious
metal alloy used for prosthetic resto-
rations in conjunction with titanium
implant bodies. Ions that leach out of
nonprecious alloys may cause bone re-
sorption, ultimately leading to failure
and even fracture of an implant. Fur-
ther investigation will be needed to
confirm these findings.
ACKNOWLEDGMENTS
We are most grateful to Dr. David
Oron, PhD, in Material Engineering,
for his helpful analysis and explana-
tions on the metallurgic aspects.
DISCLOSURE
The authors claim to have no fi-
nancial interest in any company or any
of the products mentioned in this
article.
REFERENCES
1. Levine RA, Clem DS, Wilson TG, et
al. Multicenter retrospective analysis of the
ITI implant system used for single-tooth
replacements: Results of loading for two or
more years. Int J Oral Maxillofac Implants.
1999;14:516–520.
2. Lekholm U, Van Steenberghe D,
Herrmann I, et al. Osseointegrated im-
plants in the treatment of partially edentu-
lous jaws: A prospective 5-year multicenter
study. Int J Oral Maxillofac Implants. 1994;
9:627–635.
3. Buser D, Mericske Stern R, Bernard
JP, et al. Long-term evaluation of non-
submerged ITI implants. Part 1: 8-year life
table analysis of a prospective multi-center
study with 2359 implants. Clin Oral Im-
plants Res. 1997;8:161–172.
4. Tolman DE, Laney WR. Tissue-
integrated prosthesis complications. Int
J Oral Maxillofac Implants. 1992;7:
477–484.
5. Balshi TJ. An analysis and manage-
ment of fractured implants: A clinical re-
port. Int J Oral Maxillofac Implants. 1996;
11:660–666.
6. Ragnar A, Eriksson B, Lekholm U, et
al. A long-term follow up study of os-
seointegrated implants in the treatment of
totally edentulous jaws. Int J Oral Maxillo-
fac Implants. 1990;5:347–359.
7. Grunder U, Polizzi G, Goene R, et al.
A 3-year prospective multicenter follow-up
report on the immediate and delayed-
immediate placement of implants. Int
J Oral Maxillofac Implants. 1999;14:210–
216.
8. Tonetti MS, Schmid J. Pathogenesis
of implant failure. Periodontology 2000.
1994;4:127–138.
9. Mericske-Stern R, Steinlin Schaffner
T, Marti P, et al. Peri-implant mucosal as-
pects of ITI implants supporting overden-
tures. A five-year longitudinal study. Clin
Oral Implants Res. 1994;5:9–18.
10. Jemt T, Lekholm U. Oral implant
treatment in posterior partially edentulous
jaws: A 5-year follow up report. Int J Oral
Maxillofac Implants. 1993;8:635–640.
11. Zarb G, Schmitt A. The longitudinal
clinical effectiveness of osseointegrated
dental implants: The Toronto study. Part III:
Problems and complications encountered.
J Prosthet Dent. 1990;64:185–194.
12. Takeshita F, Sutsugu T, Higuchi Y,
et al. Histologic study of failed hollow im-
plants. Int J Oral Maxillofac Implants. 1996;
11:245–250.
13. Piattelli A, Piattelli M, Scarano M, et
al. Light and scanning electron micro-
scopic report of four fractured implants. Int
J Oral Maxillofac Implants. 1998;13:561–
564.
140 FRACTURE OF DENTAL IMPLANTS
5. 14. Siddiqui AA, Caudill R. Proceed-
ings of the 4th international symposium on
implant dentistry. Focus on esthetics. San
Diego, California, January 27–29, 1994.
J Prosthet Dent. 1994;72:623–634.
15. Piattelli A, Scarano A, Vaia E, et al.
Histological evaluation of the peri-implant
bone around plasma-sprayed non-
submerged titanium implants retrieved
from man: A report of two cases. Bioma-
terials. 1996;17:2219–2224.
16. Rangert B, Jemt T. Forces and mo-
ments on Branemark implants. Int J Oral
Maxillofac Implants. 1989;4:241–247.
17. Garg AK, Morales M, Navarro I. Re-
pair of a transmandibular impar: Clinical re-
port. Implant Dent. 1997;6:11–13.
18. Rangert B, Krogh PHJ, Langer B,
et al. Bending overload and implant
fracture: A retrospective clinical analysis.
Int J Oral Maxillofac Implants. 1995;10:
326–334.
19. Jaarda MJ, Razzogg ME, Gratton
DG. Effect of preload torque on the ulti-
mate tensile strength of implant prosthetic
retaining screws. Implant Dent. 1994;
3:17–21.
20. Jaarda MJ, Razzogg ME, Gratton
DG. Providing optimum torque to implant
prostheses: A pilot study. Implant Dent.
1993;2:50–52.
21. Luterbacher S, Fourmousis I, Lang
NP, et al. Fractured prosthetic abutments
in osseointegrated implants: A technical
complication to cope with. Clin Oral Im-
plants Res. 1999;11:163–170.
22. Steflik DE, Parr GR, Singh BB, et al.
Light microscopic and SEM analyses of
dental implants retrieved from humans.
J Oral Implants. 1994;20:8–24.
23. Piattelli A, Scarano A, Paolantonio
M. Clinical and histologic features of a non-
axial load on the osseointegration of a pos-
terior mandibular implant: Report of a
case. Int J Oral Maxillofac Implants. 1998;
13:273–275.
24. Charton-Picard F, Eloy R. L’allergie
aux alliages utilises en art dentaire et a
leurs composants. Le Chirurgien Dentiste
de France. 2000;970:17–24.
25. Morgan MJ, James DF, Pilliar RM.
Fractures of the fixture component of an
osseointegrated implant. Int J Oral Maxillo-
fac Implants. 1993;4:409–414.
26. Piattelli A, Corigliano M, Scarano A.
Microscopical observations of the osseous
responses in early loaded human titanium
implants: A report of two cases. Biomate-
rials. 1996;17:1333–1337.
27. Linkow LI, Donath K, Lemons JE.
Retrieval analyses of a blade implant after
231 months of clinical function. Implant
Dent. 1992;1:37–43.
28. Hass R, Haimbock W, Mailath G, et
al. The relationship of smoking on peri-
implant tissue. J Prosthet Dent. 1996;76:
592–596.
29. Lang NP, Mombelli A, Tonetti MS,
et al. Clinical trials on therapies for peri-
implant infections. Ann Periodontol. 1997;
2:343–356.
30. Hurzeler MB, Quinones CR, Kohal
RJ, et al. Changes in peri-implant tissues
subjected to orthodontic forces. J Peri-
odontol. 1998;69:396–404.
31. Piattelli A, Scarano A, Piattelli A.
Histologic observations on 230 retrieved
dental implants: 8 years experience (1989–
1996). J Periodontol. 1998;69:178–184.
32. Eke PI, Braswell LD, Fritz ME. Mi-
crobiota associated with experimental
peri-implantitis and periodontitis in adult
Macaca mulatta monkeys. J Periodontol.
1998;69:190–194.
33. Meffert RM. Periodontitis vs. peri-
implantitis: The same disease? The same
treatment? Crit Rev Oral Biol Med. 1996;3:
278–291.
34. Rosentiel SF, Land MF, Fujimoto J.
Contemporary Fixed Prosthodontics. 2nd
ed. St. Louis: Mosby-Year Book; 1995:
416–419.
35. Turpin YL, Tardivel RD, Tallec A, et
al. Corrosion susceptibility of titanium cov-
ered by dental cements. Dent Mater. 2000;
16:57–61.
36. Lowenheim FA. Modern Electro-
plating. 2nd
ed. New York: John Wiley &
Sons; 1963:5–8, 737.
37. Esposito M, Lausmaa J, Hirsch
JM, et al. Surface analysis of failed oral
titanium implants. J Biomed Mater Res.
1999;48:559–568.
38. Esposito M, Hirsch JM, Lekholm U,
et al. Biological factors contributing to fail-
ures of osseointegrated oral implants. (I).
Success criteria and epidemiology. Eur
J Oral Sci. 1998;106:527–551.
39. Morais S, Sousa JP, Fernandes
MH, et al. Decreased consumption of Ca
and P during in-vitro biomineralization and
biologically induced deposition of Ni and
Cr in the presence of stainless steel corro-
sion products. J Biomed Mater Res. 1998;
42:199–212.
40. Charton-Picard F, Eloy R. L’allergie
aux alliages utilises en art dentaire et a
leurs composants. Le Chirurgien Dentiste
de France. 2000;970:17–24.
Reprint requests and correspondence to:
Nirit Tagger Green, DMD, MSc, MHA
Unit of Periodontology
Rambam Medical Center
PO Box 99102
Haifa 31096
Israel
E-mail: tagreen@netvision.net.il
IMPLANT DENTISTRY / VOLUME 11, NUMBER 2 2002 141
6. Abstract Translations [German, Spanish, Portuguese, Japanese]
AUTOR(EN): Nirit Tagger Green D.M.D.,
M.Sc., M.H.A.*, Eli E. Machtei D.M.D.***,
Jacob Horwitz D.M.D.*, Micha Peled M.D.,
D.M.D.*, **, ***. *Abteilung für Periodon-
tologie, Medizinisches Zentrum Rambam,
Haifa, Israel. **Medizinische Fäkultät,
Techniker-I.I.T., Haifa, Israel. ***Fachbe-
reich Mund- und Kieferchirurgie, Medizinis-
ches Zentrum Rambam, Haifa, Israel. Schrift-
verkehr: Nirit Tagger Green, DMD, MSc,
MHA, Unit of Periodontology, Rambam Med-
ical Center, PO Box 99102, Haifa 31096, IS-
RAEL. eMail: tagreen@netvision.net.il
ZUSSAMENFASSUNG: Zahnimplantatsbrüche kommen zwar selten vor, ziehen dann
aber schwerwiegende klinische Konsequenzen nach sich. Im vorliegenden Bericht erfolgt
ein Überblick über die Literatur, außerdem werden ursächliche Gründe für eine Implan-
tatsfraktur vorgestellt. Galvanische Aktivität, die bei Kontakt zum Oberbau auftreten
kann, wurde bislang noch nie mit der Entstehung von Implantatsbrüchen in Verbindung
gebracht. Dieses Phänomen kann durch den Fall eines Titanimplantats näher beleuchtet
werden, das nach Wiederherstellung mittels unedler PFM-zementierter Krone 4 Jahre
nach Belastung eine Fraktur aufwies. Bei Röntgenuntersuchungen wurde alveolare
Knochenresorption rund um die Anlagerungsstelle festgestellt. Metallurgische Analysen
ergaben, dass die Implantatsfraktur durch Ermüdungserscheinungen im Metall hervorg-
erufen wurde. Auch wurde innerhalb dieser Untersuchungen festgestellt, dass das Metall
der Krone, eine Nickel-Chrom-Molybdän-Legierung, korrodierte. Aufgrund dieser Ergeb-
nisse kann der neuartige Rückschluss bezüglich der Entstehung von Implantatsfrakturen
erfolgen, dass aus der Basismetalllegierung austretende zytotoxische Nickelionen zu
Knochenresorption führen können. Dies resultiert in einer erhöhten Implantatbeweglich-
keit, die wiederum eine Auswaschung des verbindenden Zements wahrscheinlicher macht.
Durch den Kontakt des Basismetalls zum Titan bei Vorliegen von Mundflüssigkeit
werden galvanische Ströme erzeugt, die eine Korrosion und ein Auswaschen von Nick-
elionen begünstigen. Als Resultat tritt weitere Knochenresorption auf, die aufgrund des
dann fehlenden Haltes durch die Knochensubstanz zu lateralen Flexionen im Metall und
somit zu Ermüdungserscheinungen und eventuell Frakturen führen kann. Daher ist eine
sorgfältige Behandlungsplanung und verantwortungsbewusste Fallauswahl für eine Ver-
meidung solcher Brüche unabdingbar. Auch sollte berücksichtigt werden, dass die Ver-
wendung unedler Metalllegierungen für die Krone ebenfalls zum letztendlichen Bruch des
Implantats beiträgt.
SCHLÜSSELWÖRTER: Zahnimplantate, Fraktur, galvanische Korrosion, Nickel, Ermü-
dungserscheinungen im Metall
AUTOR(ES): Nirit Tagger Green, D.M.D.,
M.Sc., M.H.A.*, Eli E. Machtei, D.M.D.***,
Jacob Horwitz, D.M.D.*, Micha Peled, M.D.,
D.M.D.*,**,***. *Unidad de Periodon-
tología, Centro Médico Rambam, Haifa, Is-
rael. **Facultad de Medicina, Técnico I.I.T,
Haifa, Israel. ***Departamento de Cirugía
Oral y Maxilofacial, Centro Médico Ramban,
Haifa, Israel. Correspondencia a: Nirit Tag-
ger Green, DMD, MSc, MHA, Unit of Peri-
odontology, Rambam Medical Center, P.O.
Box 99102, Haifa 31096 ISRAEL. Correo
electrónico: tagreen@netvision.net.il
ABSTRACTO: La fractura de implantes dentales es un fenómeno raro con severos
resultados clínicos. Se hace una revisión de la literatura sobre el tema y los distintos
factores causales que pueden llevar a la presentación de la fractura. La actividad galvánica
no se ha mencionado antes como una posible causa de la fractura del implante, sin
embargo, puede ocurrir al nivel del contacto con la superestructura. Esto lo ilustra el caso
de un implante de titanio restaurado con una corona de porcelana fusionada a metal no
precioso que se fracturó cuatro años después de la carga. Las radiografías muestran la
reabsorción del hueso alveolar alrededor del aparato. El análisis metalúrgico del implante
indicó que la fractura fue causada por la fatiga del metal y que el metal de la corona, una
aleación de níquel, cromo y molibdeno exhibieron corrosión. Estas conclusiones de la
fatiga sugieren una nueva explicación de la fractura de los implantes: iones de níquel
citológicos, que salen de la aleación del metal de la base podría causar la reabsorción del
hueso. Esto a su vez lleva a una mayor movilidad que facilita la eliminación del cemento
para moldes. El contacto del metal de la base con el titanio en la presencia de líquidos
orales produce corrientes galvánicas que aceleran la corrosión y eliminación de iones de
níquel, llevando a una reabsorción adicional del hueso. La pérdida del soporte del hueso
permite momentos de movimientos laterales que causan fatiga del metal eventualmente
llevando a la fractura. Por lo tanto, una buena planificación del tratamiento y selección
apropiada del caso podría haber prevenido esta fractura. Además, el uso de una aleación
de metal no precioso para la infraestructura de la corona podría haber contribuido
adicionalmente a la cadena de eventos que llevó a la fractura del implante.
PALABRAS CLAVES: implantes dentales, fractura, corrosión galvánica, níquel, fatiga
del metal
142 FRACTURE OF DENTAL IMPLANTS
7. AUTOR(ES): Nirit Tagger Green D.M.D.,
M.Sc., M.H.A.*, Eli E. Machtei D.M.D.***,
Jacob Horwitz D.M.D.*, Micha Peled M.D.,
D.M.D.* ** ***. *Unidade de Periodontia,
Centro Médico Rambam, Haifa, Israel.
**Faculdade de Medicina, Técnico-I.I.T.,
Haifa, Israel. ***Departamento de Cirurgia
Oral e Maxilofacial, Centro Médico Rambam,
Haifa, Israel. Correspondências devem ser en-
viadas a: Nirit Tagger Green, DMD, MSc,
MHA, Unidade de Periodontia, Centro Médico
Rambam, P. O. Box 99120, Haifa 31096, IS-
RAEL. e-mail: tagreen@netvision.net.il
SINOPSE: a fratura de implantes odontológicos é um fenômeno raro com resultados
clínicos severos. A literatura foi revisada e vários fatores causadores que podem levar à
fratura são apresentados. Atividade galvânica não foi mencionada anteriormente como
uma causa possível de fratura de implante. Entretanto, a mesma pode ocorrer no ponto de
contato com a superestrutura. Isto pode ser observado no caso de um implante de titânio
restaurado com uma coroa cimentada PFM não preciosa fraturada 4 anos após a colo-
cação. As radiografias mostram reabsorção do osso alveolar ao redor do suporte de
fixação. Uma análise metalúrgica do implante indicou que a fratura foi causada por fadiga
do material e que o metal da coroa, uma liga de níquel-cromo-molibdênio, apresentou
corrosão. Estas observações sugerem uma nova explicação para fraturas de implantes: íons
de níquel citotóxicos e lixiviação vinda da liga de metal da base podem causar reabsorção
do osso. Isto, por sua vez, leva a uma maior mobilidade, facilitando a lavagem do cimento
de obturação. O contato da base de metal com o titânio na presença dos fluídos bucais
produz correntes galvânicas que aceleram a corrosão e a lixiviação dos íons de níquel,
causando assim ainda mais reabsorção. A perda do suporte ósseo permite momentos de
movimentação lateral que causam fatiga do material, eventualmente levando à fratura.
Portanto, um bom planejamento de tratamento e uma seleção apropriada de caso poderiam
ter evitado tal fratura. Ademais, a utilização de uma liga de metal não precioso para a
infra-estrutura da coroa contribui com a cadeia de eventos que levou à fratura do implante.
PALAVRAS-CHAVES: implantes odontológicos, fratura, corrosão galvânica, níquel,
fadiga de material
IMPLANT DENTISTRY / VOLUME 11, NUMBER 2 2002 143