Teriparatide is a recombinant form of parathyroid hormone that stimulates new bone formation and increases bone mineral density by activating osteoblasts. It is produced through recombinant DNA technology and used to treat osteoporosis by increasing the number and activity of osteoblasts, decreasing their programmed death, and recruiting more osteoblasts. Common side effects include muscle cramps, leg cramps, joint pain, and symptoms of a cold like cough and runny nose.

1. FORTEO
TERIPARATIDE
BY:- MOHAMMAD SAMEER
BSC BT II YEAR

3. DESCRIPTION
Teriparatide (recombinant human
parathyroid hormone) is a potent
anabolic agent used in the treatment
of osteoporosis.
Teriparatide is a recombinant
protein form of parathyroid hormone.
It is also occasionally used to speed
fracture healing.
It is produced in E.Coli through
recombinant dna technology.

4. MECHANISM OF ACTION
Daily injections of teriparatide
stimulates new bone formation leading to
increased bone mineral density.
Through activation of various bone
metabolic pathways, the PTH drug
(Forteo) increases the number of active
osteoblasts (bone-building cells),
decreases the naturally programmed
death of osteoblast cells, and recruits
bone-lining cells as osteoblasts.
This drug appears to act largely upon
the bone-building osteoblast cells
stimulating them to overactivity.

5. SIDE EFFECTS
muscle cramps or spasms,
leg cramps,
joint pain,
cough,
sore throat,
runny nose,
headache,
neck pain,

6. THANK YOU