Chemforce is a supplement designed to boost testosterone levels in men through its main ingredient, Furosap, a fenugreek seed extract. It contains protodioscin which increases the conversion of testosterone to DHT, promoting muscle growth, bone health, and sexual function. Clinical studies showed Furosap improved free testosterone levels without side effects. Increased testosterone leads to greater protein synthesis and muscle mass. Testosterone also supports bone health by promoting bone cell activity and conversion to estrogen. Chemforce aims to maintain testosterone levels for hypogonadal men to support muscle and bone health.

1. CHEMFORCE is a Muscle Mass and Bone Health Inducer It is a precise & amp; powerful blend of cutting
edge natural ingredients designed to support healthy testosterone activity levels. It has been devised
exclusively for men over the age of 18, featuring one of the highest ultra powerful protodioscin contents
available.
Chemforce contains a patent-protected protodioscin developed from fenugreek seed extract which has
been developed for boosting testosterone levels in men. Men with erectile dysfunction or hypogonadism
are unable to produce normal quantity of testosterones in the body due to which many complications
arise. Furosap ® , the main ingredient in Chemforce is a clinically proven remedy to maintain
normal testosterone levels in men.
PROTODIOSCIN
Protodioscin is the active constituent in Chemforce which is responsible for testosterone boosting in men.
The site of action of protodioscin is the enzyme named 5-α-reductase. This enzyme catalyzes the
conversion of testosterone to dihydro testosterone (DHT). This conversion is more beneficial for men as
DHT is more active form of testosterone in the body. This increase in DHT levels promotes the muscle
development, makes the bones healthy, activates RBCs and thus, promotes healthy sexual functions in
men.
Protodioscin helps to increase androgen receptors in the cells due to which more testosterone is attached
to the respective receptors of the cells to promote libido in men and helps to improve erectile dysfunction.

2. TESTOSTERONE & Muscle Mass and Bone Health Inducer
Testosterone is the primary hormone responsible for muscle growth. Testosterone triggers muscle
growth by protein synthesis in muscular tissue. Testosterone generates a response in the muscular tissue
due to which body itself increases the strength and size of muscular tissue by adding new protein strands
to muscle fibers. This results in the increase in Muscle Mass and Bone Health Inducer.
Testosterone generates the response in muscular tissue by binding to receptors on the surface of muscle
cells and intensifies the biochemical signals in muscle tissue that results in protein
synthesis. Testosterone also increases levels of another growth factor, called growth hormone, which the

3. body releases in response to exercise. Like testosterone, growth hormone also increases protein
synthesis and result in increased muscle growth.
By any way, testosterone boosts protein synthesis in skeletal muscle. The result of all of the functions
by testosterone is an overall increase in muscular size, strength and recovery from exercise.
Furosap ® treatment: Swaroop A et al. performed clinical study of fenugreek seed extract - Furosap ® in
male volunteers. The single armed and open labeled study proved that Furosap ® was effective in
improving testosterone levels in men.
This clinical study of Furosap ® found that:
 Free testosterone levels were improved up to 46% in the enrolled population.
 Furosap ® was also proved to be safe in humans as there was no significant change in serum lipid
function, cholesterol, triglyceride, HDL and LDL levels, hemogram (CBC), hepatotoxicity and
nephrotoxicity.
 It can also be interpreted from this clinical study that free testosterone levels improved by Furosap ®
might also be effective in muscle growth.
Aswar U et al. also studied the effect of fenugreek on reproductive system of male Wistar rats. They
found that fenugreek was completely safe in the animals and effective in producing positive reproductive
effects. Fenugreek increased muscle mass and body weight in the animals at the end of the treatment.
They reported that anabolic agents increase protein synthesis within cells, which results in the buildup of
cellular tissue (anabolism), especially in muscles. Fenugreek also increased the anabolic activity in the
rats which resulted in increased protein synthesis in the muscles. They also reported that fenugreek

4. furostanol glycoside possessed anabolic activity which increased muscle mass in the rats. This promoted
the muscle strength and mass.
Griggs RC et al. has also reported that testosterone increased muscle mass by promoting muscle protein
synthesis. They studied the effect of testosterone dose in normal male subjects. They found
that testosterone increased the muscle mass up to 27% in all the male subjects without any side effect.
TESTOSTERONE & Muscle Mass and Bone Health Inducer
Testosterone plays an important role in the bone cell function & bone density. It acts in a dual mode of
action in bone cells i.e. via
 Androgen receptor
 Estrogen receptor
Androgen receptor: It has been reported by a study that bone cells have androgen receptors. This
androgen receptor is the acting site for the more active form of testosterone i.e. dihydrotestosterone.
Once DHT is attached at the receptor on bone cells, they might promote proliferation and differentiation of
osteoblasts, inhibit osteoclast recruitment or affect osteoblast-to-osteoclast signaling. This promotes bone
health.
Estrogen receptor: Testosterone is converted into estradiol via aromatization in many tissues including
male bone. This conversion is catalyzed by P 450 aromatase enzyme, which is present in many
peripheral tissues, including bone. The converted estradiol attaches itself on estorogen receptors (ERα or
ERβ) in bone cells which contributes to the maintenance of bone mass after reaching peak bone mass.

5. Animal studies have also confirmed that the estrogen receptor activation is involved in the regulation of
male skeletal growth.
Chemforce treatment: Considering the reported data, if testosterone levels are maintained in
hypogonadal men, then, bone health can also be maintained. Fenugreek seed extract – Chemforce is
such food supplement which is reported to boost testosterone levels in hypogonadal men. When
the testosterone levels are boosted in men, then bone health might also be maintained by this hormone
via any of the given mechanism.
Another ingredient in Chemforce, Alpha Yohimbine is a known aphrodisiac.
REFERENCES
 http://chereso.net/furosap/
 http://www.naturally-boost-testosterone.com/fenugreek-and-testosterone/
 http://www.livestrong.com/article/68797-testosterone-muscle-growth/
 http://www.fasebj.org/content/30/1_Supplement/1156.7.short
 http://jap.physiology.org/content/66/1/498
 http://renegadehealth.com/blog/2014/04/04/testosterone-boosters-is-the-latest-supplement-safe-for-men
 https://www.researchgate.net/profile/Urmila_Aswar/publication/46580790_Effect_of_furostanol_glycoside
s_from_Trigonella_foenum-
graecum_on_the_reproductive_system_of_male_albino_rats_Phytother_Res/links/568e3b4c0
8ae78cc05152ed1.pdf
 https://www.researchgate.net/profile/Roger_Francis4/publication/12830916_Effects_of_testosterone_on_
osteoporosis_in_men/links/540f38000cf2df04e75a296d.pdf
 https://www.hindawi.com/journals/jos/2011/240328/
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