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SYNTHETIC BIOLOGY
Aleksandra Nivina	

Bodyware expedition	

March 14, 2014
WHAT DOES SYNTHETIC BIOLOGY MEAN ?
fuel
prevent ageing
gene	

therapy
reprogram	

microflora
WHAT COULD SYNTHETIC BIOLOGY DO ?
new materials
bioremediation
biosensors
drugs
cancer	

therapies
improved	

crops
cosmetics
gene	

therapy
fuel
prevent ageing
reprogram	

microflora
WHAT COULD SYNTHETIC BIOLOGY DO ?
new materials
bioremediation
biosensors
drugs
cancer	

therapies
improved	

crops
cosmetics
sciences and digital technology offers an exciting
and unlimited range of applications. We invite
you to imagine the future of our bodies.
THEMES
The workshop will be focused on the themes of
the Bodyware expedition :
SENSE
IDENTITY
BE WELL
BE MORE
PERFORMANCE
HEALTH
BEAUTY
This workshop aims to cat
between the actors of digital
in order to productively wor
expedition
AGENDA
Friday March 14:
- Inspiring talks
- Bio-design Exploration: disco
brainstorm,…
- Working groups: scenario de
Saturday March 15:
- Working groups: product de
Tuesday March 18:
- Projects presentation and re
CONTACT
Thierry Marcou
tmarcou@fing.org
Justine Coubard-Millot
jcoubardmillot@fing.org
Helena Shomar
helena.shomar@gmail.com
Marguerite Benony
marguerite.benony@gmail.com
SYNTHETIC BIOLOGY AND DESIGN
“designing a genetic circuit”
“creating new proteins by rational design”
“designing an experiment”
“designing DNA fragments”
if [A]>threshold then	

produce B;	

produce C;	

end
Promoter Ribosome	

Binding	

Site
Ribosome	

Binding	

Site
Gene B Gene C
Terminator
A A A
A
A
Produce proteins B and C in response to molecule A
DESIGNING A GENE CIRCUIT
DESIGNING MORE COMPLEX SYSTEMS
Mycoplasma laboratorium
“simple” genetic circuits
complex gene networks
SYNTHETIC BIOLOGY AND DESIGN
Synthetic Biology	

!
designing systems to be:	

simple	

robust	

efficient	

bio-safe	

...
Other areas of design	

!
designing objects to be:	

easy to use	

sustainable	

practical	

eco-friendly	

...
imposed constraints:	

part availability	

non-compatibility	

ethics	

...
imposed constraints:	

material availability	

non-compatibility	

guidelines and regulations	

...
+ creativity! + creativity!
SYNTHETIC BIOLOGY AS A NEW AREA OF DESIGN
finding new applications
product development
CAD tool	

development
art
process
design
collaborations
THANKYOU FORYOUR ATTENTION	

AND HAVE A NICE EXPEDITION!

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Workshop Fing-CRI : Synthetic Biology, by Aleksandra Nivina

  • 2. WHAT DOES SYNTHETIC BIOLOGY MEAN ?
  • 3. fuel prevent ageing gene therapy reprogram microflora WHAT COULD SYNTHETIC BIOLOGY DO ? new materials bioremediation biosensors drugs cancer therapies improved crops cosmetics
  • 4. gene therapy fuel prevent ageing reprogram microflora WHAT COULD SYNTHETIC BIOLOGY DO ? new materials bioremediation biosensors drugs cancer therapies improved crops cosmetics sciences and digital technology offers an exciting and unlimited range of applications. We invite you to imagine the future of our bodies. THEMES The workshop will be focused on the themes of the Bodyware expedition : SENSE IDENTITY BE WELL BE MORE PERFORMANCE HEALTH BEAUTY This workshop aims to cat between the actors of digital in order to productively wor expedition AGENDA Friday March 14: - Inspiring talks - Bio-design Exploration: disco brainstorm,… - Working groups: scenario de Saturday March 15: - Working groups: product de Tuesday March 18: - Projects presentation and re CONTACT Thierry Marcou tmarcou@fing.org Justine Coubard-Millot jcoubardmillot@fing.org Helena Shomar helena.shomar@gmail.com Marguerite Benony marguerite.benony@gmail.com
  • 5. SYNTHETIC BIOLOGY AND DESIGN “designing a genetic circuit” “creating new proteins by rational design” “designing an experiment” “designing DNA fragments”
  • 6. if [A]>threshold then produce B; produce C; end Promoter Ribosome Binding Site Ribosome Binding Site Gene B Gene C Terminator A A A A A Produce proteins B and C in response to molecule A DESIGNING A GENE CIRCUIT
  • 7. DESIGNING MORE COMPLEX SYSTEMS Mycoplasma laboratorium “simple” genetic circuits complex gene networks
  • 8. SYNTHETIC BIOLOGY AND DESIGN Synthetic Biology ! designing systems to be: simple robust efficient bio-safe ... Other areas of design ! designing objects to be: easy to use sustainable practical eco-friendly ... imposed constraints: part availability non-compatibility ethics ... imposed constraints: material availability non-compatibility guidelines and regulations ... + creativity! + creativity!
  • 9. SYNTHETIC BIOLOGY AS A NEW AREA OF DESIGN finding new applications product development CAD tool development art process design collaborations
  • 10. THANKYOU FORYOUR ATTENTION AND HAVE A NICE EXPEDITION!