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IMAGE OF THE WEEK
M7 UNIT
PROF DR.THILAKAVATHI.R M.D
DR.MADHUSUDHANAN M.D
DR.ELANGOVAN M.D
BY DR.DHARANI L
(FIRST YEAR POSTGRADUATE)
CASE HISTORY
 A 45 year old male presented with
C/O cough with expectoration for 1 month
C/O decreased appetite
C/O hemoptysis – 2 episodes each around 2-3 ml
of blood in sputum
PAST HISTORY
 Not a known case of Pulmonary TB/T2DM/SHTN
 Not a known case of CVA, CAD, CKD
 No H/o covid 19 infection, both dose vaccinated
PERSONAL HISTORY
 Mixed diet
 Normal bowel and bladder habbits
 Known occasional alcoholic for past 10 years
 Known chronic smoker for past 20 years ( 1 pack
/day)
ON EXAMINATION
 Patient conscious
 Oriented
 Afebrile
 Hydration fair
 Clubbing – Grade II
BP- 120/70, PR- 108/ min, SPO2-96% in RA
CVS: S1S2 +, No murmur
RS: trachea in midline ,trial sign negative,
Normal vescicular breath sounds heard in all areas except left
supraclavicular and infraclavicular areas
Impaired resonance in left supraclavicular and supraclavicular
areas
VF, VR reduced in above areas
P/A: Soft, BS+, No organomegaly
CNS: No focal neurological deficit
CHEST XRAY PA VIEW
INTERPRETATION
 Frontal view of xray chest
 Full inspiratory film
 Adequate exposure
 Overpenetration present
 Trachea mildly deviated to left
 B/L lung field appears hyperinflated
 Mediastinum appears to be mildly shifted towards
left
 Left cardiophrenic angle appears to be blunted
 A heterogenous opacity noted in the left upper zone
with air around the opacity taking crescent shape
DIFFERENTIAL DIAGNOSIS
LEFT UPPER LOBE MASS
Tuberculosis
Single pulmonary nodule
Consolidation
Fungal ball- Aspergilloma
Abscess
Malignancy
CT CHEST
CT REPORT
 A well defined special soft tissue density mass of
4*3 cm in apicoposterior segment of left upper
lobe with eccentric air locule taking crescent shape
– suggestive of aspergilloma
INVESTIGATION
SPUTUM KOH MOUNT – Aspergillus fumigatus with
thin septate hyphae of acute angle
SPUTUM AFB – Negative
DIAGNOSIS
 A thin walled cavity with fungal ball aspergilloma –
probably post TB sequela
CT REPORT
 Fibrocavity measuring 3x2 cm in left upper lobe
apicoposterior segment with heterodense calcified
intracavitory body noted within the cavity
 Surrounded by crescent of air
 Multifocal patchy fibrosis noted in the left upper
lobe with traction bronchiectatic changes
 Possibly old infective sequela with fungal ball
SINGLE PULMONARY NODULE
 Well defined round or
oval </= 3 cm in
diameter surrounded
by pulmonary
parenchyma
CONSOLIDATION
 Airspace opacificaion
causing obscuration of
pulmonary vessels wih air
bronchograms
MALIGNANCY
 Round/ oval
opacities more
than 30 mm
LUNG ABSCESS
 Cavity containing gas fluid level
 Thick walled
CHRONIC PULMONARY
ASPERGILLOSIS
 It is a chronic progressive and destructive
parenchmal lung infection
 90 % in patients with current or previous underlying
lung disease or immune deficit
 Radiological presentation with formation of new
cavities or expansion of existing ones +/- fungal ball
or nodule
RADIOLOGICAL PHENOTYPES
 Simple aspergilloma
 Chronic cavitory pulmonary aspergillosis
 Aspergillus nodule
 Chronic fibrosing pulmonary aspergillosis
 Invasive pulmonary aspergillosis
RISK FACTORS
 Tuberculosis
 COPD +/- Emphsema
 Non – tuberculous mycobacterial infection
 Pneumothorax/bullous lung disease
 Allergic bronchopulmonary aspergillosis
 Pulmonary fibrocystic sarcoidosis
 Lung irradiation
 Rheumatoid arthritis
 Ankylosing spondylitis
ASPERGILLUS NODULES
 Occurs in immunocompetent hosts
 May be single/multiple with or without cavitation
 Patient are usually asymptomatic or have minor
pulmonary symptoms
 Aspergillus IgG titre may be rised
 Natural history is poorly described , but prognosis is
good
A SINGLE ASPERGILLOMA
 Single pulmonary aspergilloma is a single fungal
ball in a single pulmonary cavity
 Serological / microbiological evidence may
implicate Aspergillus spp
 No radiological progression over months of
observation
 Persistent pulmonary/ systemic symptoms
 Can be complicated by sudden , potentially fatal
hemoptysis
 MONAD SIGN – change of fungal ball position
within the cavity
CHRONIC CAVITARY PULMONARY
ASPERGILLOSIS
 Formation or expansion of existing cavities (usually
multiple ) is charecteristic
cavities may or may not contain an
aspergilloma ( fungal ball)
 Associated with high mortality (50-85% at 5 years)
cause of death include severe haemoptysis
and respiratory failure
 Mostly associated with underlying defect in innate
immunity
CHRONIC FIBROSING PULMONARY
ASPERGILLOSIS
 Extensive fibrosis with fibrotic destruction of atleast
two lobes of lung
 With major loss of lung function
 Represent an end result of untreated CCPA
 One or more aspergillomas may be present
 Seroloical/microbiological evidence is required for
diagnosis
INVASIVE PULMONARY
ASPERGILLOSIS
 Sub acute invasive / Chronic necrotising /
Semi invasive aspergillosis
 Airway invasive aspergillosis-
Bronchopneumonic aspergillosis
 Angio invasive aspergillosis
HALO SIGN
 Ground glass opacity
surrounding a
pulmonary nodule
represents
hemorrhage- in active
phase of IPA
AIR CRESCENT SIGN
 Half moon shaped lung tissue
 In recovery phase –peripheral absorption of
necrotic tissue causes the retraction of infarcted
area
final image of week dharu1.pptx

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final image of week dharu1.pptx

  • 1. IMAGE OF THE WEEK M7 UNIT PROF DR.THILAKAVATHI.R M.D DR.MADHUSUDHANAN M.D DR.ELANGOVAN M.D BY DR.DHARANI L (FIRST YEAR POSTGRADUATE)
  • 2. CASE HISTORY  A 45 year old male presented with C/O cough with expectoration for 1 month C/O decreased appetite C/O hemoptysis – 2 episodes each around 2-3 ml of blood in sputum
  • 3. PAST HISTORY  Not a known case of Pulmonary TB/T2DM/SHTN  Not a known case of CVA, CAD, CKD  No H/o covid 19 infection, both dose vaccinated PERSONAL HISTORY  Mixed diet  Normal bowel and bladder habbits  Known occasional alcoholic for past 10 years  Known chronic smoker for past 20 years ( 1 pack /day)
  • 4. ON EXAMINATION  Patient conscious  Oriented  Afebrile  Hydration fair  Clubbing – Grade II BP- 120/70, PR- 108/ min, SPO2-96% in RA CVS: S1S2 +, No murmur RS: trachea in midline ,trial sign negative, Normal vescicular breath sounds heard in all areas except left supraclavicular and infraclavicular areas Impaired resonance in left supraclavicular and supraclavicular areas VF, VR reduced in above areas P/A: Soft, BS+, No organomegaly CNS: No focal neurological deficit
  • 6.
  • 7. INTERPRETATION  Frontal view of xray chest  Full inspiratory film  Adequate exposure  Overpenetration present  Trachea mildly deviated to left  B/L lung field appears hyperinflated  Mediastinum appears to be mildly shifted towards left  Left cardiophrenic angle appears to be blunted  A heterogenous opacity noted in the left upper zone with air around the opacity taking crescent shape
  • 8. DIFFERENTIAL DIAGNOSIS LEFT UPPER LOBE MASS Tuberculosis Single pulmonary nodule Consolidation Fungal ball- Aspergilloma Abscess Malignancy
  • 10.
  • 11. CT REPORT  A well defined special soft tissue density mass of 4*3 cm in apicoposterior segment of left upper lobe with eccentric air locule taking crescent shape – suggestive of aspergilloma
  • 12. INVESTIGATION SPUTUM KOH MOUNT – Aspergillus fumigatus with thin septate hyphae of acute angle SPUTUM AFB – Negative
  • 13. DIAGNOSIS  A thin walled cavity with fungal ball aspergilloma – probably post TB sequela
  • 14.
  • 15.
  • 16.
  • 17.
  • 18. CT REPORT  Fibrocavity measuring 3x2 cm in left upper lobe apicoposterior segment with heterodense calcified intracavitory body noted within the cavity  Surrounded by crescent of air  Multifocal patchy fibrosis noted in the left upper lobe with traction bronchiectatic changes  Possibly old infective sequela with fungal ball
  • 19. SINGLE PULMONARY NODULE  Well defined round or oval </= 3 cm in diameter surrounded by pulmonary parenchyma
  • 20. CONSOLIDATION  Airspace opacificaion causing obscuration of pulmonary vessels wih air bronchograms
  • 22. LUNG ABSCESS  Cavity containing gas fluid level  Thick walled
  • 23. CHRONIC PULMONARY ASPERGILLOSIS  It is a chronic progressive and destructive parenchmal lung infection  90 % in patients with current or previous underlying lung disease or immune deficit  Radiological presentation with formation of new cavities or expansion of existing ones +/- fungal ball or nodule
  • 24. RADIOLOGICAL PHENOTYPES  Simple aspergilloma  Chronic cavitory pulmonary aspergillosis  Aspergillus nodule  Chronic fibrosing pulmonary aspergillosis  Invasive pulmonary aspergillosis
  • 25. RISK FACTORS  Tuberculosis  COPD +/- Emphsema  Non – tuberculous mycobacterial infection  Pneumothorax/bullous lung disease  Allergic bronchopulmonary aspergillosis  Pulmonary fibrocystic sarcoidosis  Lung irradiation  Rheumatoid arthritis  Ankylosing spondylitis
  • 26.
  • 27. ASPERGILLUS NODULES  Occurs in immunocompetent hosts  May be single/multiple with or without cavitation  Patient are usually asymptomatic or have minor pulmonary symptoms  Aspergillus IgG titre may be rised  Natural history is poorly described , but prognosis is good
  • 28. A SINGLE ASPERGILLOMA  Single pulmonary aspergilloma is a single fungal ball in a single pulmonary cavity  Serological / microbiological evidence may implicate Aspergillus spp  No radiological progression over months of observation  Persistent pulmonary/ systemic symptoms  Can be complicated by sudden , potentially fatal hemoptysis  MONAD SIGN – change of fungal ball position within the cavity
  • 29.
  • 30. CHRONIC CAVITARY PULMONARY ASPERGILLOSIS  Formation or expansion of existing cavities (usually multiple ) is charecteristic cavities may or may not contain an aspergilloma ( fungal ball)  Associated with high mortality (50-85% at 5 years) cause of death include severe haemoptysis and respiratory failure  Mostly associated with underlying defect in innate immunity
  • 31.
  • 32. CHRONIC FIBROSING PULMONARY ASPERGILLOSIS  Extensive fibrosis with fibrotic destruction of atleast two lobes of lung  With major loss of lung function  Represent an end result of untreated CCPA  One or more aspergillomas may be present  Seroloical/microbiological evidence is required for diagnosis
  • 33. INVASIVE PULMONARY ASPERGILLOSIS  Sub acute invasive / Chronic necrotising / Semi invasive aspergillosis  Airway invasive aspergillosis- Bronchopneumonic aspergillosis  Angio invasive aspergillosis
  • 34. HALO SIGN  Ground glass opacity surrounding a pulmonary nodule represents hemorrhage- in active phase of IPA
  • 35. AIR CRESCENT SIGN  Half moon shaped lung tissue  In recovery phase –peripheral absorption of necrotic tissue causes the retraction of infarcted area