Formulations being dispensed in Pakistan in present time.

1. FCCU PHARM
EXTEMPORANEOUS
FORMULATIONS
Created By: Maira, Faryal, Paldeep, Varun
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2. TABLE
of contents
• Extemporaneous
Compounding?
• Aim of our work
• Location and
Contact
• Findings on
extemporaneous
preperations
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3. EXTEMP.COMPOUNDING
• The process of creating a medicinal substance
on the spot for a specific patient in response to
a recognized need
• A vast range of products can contain active
pharmaceutical ingredients. Simple
compounding can be performed by any
pharmacist and is a core competency of
pharmacy training.

4. OUR AIMS
• Where can they be
obtained?
• Which preparations are
available?
• What purpose do they
serve?

5. PHARMACIES:
• D.Watson,
• Shaheen Chemist
• Fazal Din's Pharma
Plus

6. OUR CONTACT
Compounding and dispensing of
extemporaneous preparations can only be
done by a licensed and qualified pharmacist.
We were put into contact with one such
pharmacist at FDPP.
awais.imran.9120@gmail.com
Pharmacy License no:
05-352-0063 054185P
Muhammad Awais
Pharmacist In Charge

7. Our
Findings

8. Formulation Name Use Special Notes
MTG
Oil
Weight Management, Energy Boost,
Ketogenic Diet Support, Brain Health, Digestive Health, and
Skincare.
Oral formulation for
children to
fulfill nutritional
requirements
Spironolactone High Blood Pressure, Heart
Failure, and Edema -
Captopril High Blood Pressure
(Hypertension), Heart Failure, and Certain Kidney Disorders Liquid preparation
Sildenafil
Sulfate
Erectile Dysfunction (Ed) and
Pulmonary Arterial Hypertension (Pah)
Reduced dose to 1/4th of
the
actual dose for children
Sulphur
Ointment Acne, Rosacea, and Scabies -
Clobetasol
Ointment Eczema, Psoriasis, and Dermatitis
White soft paraffin, sulfur
and
clobetasol used in
formulation
Vitamin-C
Serum
Brighten The Complexion, Even Out
Skin Tone, Stimulate Collagen Production, and Reduce The
Appearance Of Fine
Lines and Wrinkles
-
Injections
of Phenol In
Emollient Oil
Mainly for Hemorrhoids -

9. Formulation Name Use Special Notes
Eusol
Solution
Antiseptic Properties, Helping To
Cleanse Wounds, Prevent Infection, and Promote Healing,
Wound Irrigation,
Dressing
Given in diabetic foot
Diazepam
Suppository
Treat Anxiety, Seizures, Muscle
Spasms, and Alcohol Withdrawal Symptoms -
Diltiazem
Hydrochloride
Calcium Channel Antagonist,
Prevents Angina Pectoris, But It Is Also Used in Coronary
Heart Disease With
Tachycardia And Arterial Hypertension.
Liquid Formulation
Moxifloxacin
In Fluoroquinolones Class Of
Antibiotics. It Works By Killing The Bacteria That Cause
Infections.
Suspension
Ribavirin Treat All Forms Of Viral Hepatitis
And Lassa Fever Suspension
Sildenafil
Citrate
Drug With A Narrow Therapeutic
Index Used In Pediatrics To Treat Pulmonary Hypertension. Oral Formulation
Hydrocortisone
Hydrocortisone
tablets are a steroid medication that decreases inflammation,
slows down an
overactive immune system.
Orally Administrated
Naloxone
Administered Orally To Diminish
Opioid-Related Constipation -

10. Formulation
Name
Use Special Notes
Oral Powder Of
Baclofen
Skeletal Muscle Relaxant For Multiple Sclerosis
Patients And Pediatric
Patients With Cerebral Palsy
Clonidine
Hydrochloride
Oral Powder
Clonidine Hydrochloride Is Used To Treat Sedative
Agent Withdrawals,
Malignant Hypertension, And Anesthesia
Complications.
A Commercially
Available Enteral Form
Of Clonidine, Catapres®
Tablets,
Is Compounded Into A
Powder To Achieve
Dosage Adjustments For
Pediatric
Patients.

13. ALPHA ARBUTIN
CREAM
• Concentrated 7% w/w a-arbutin cream
• Prepared using O/W emulsions
• Beyond-use date of 60 days when stored
at room temperature (30°C) and in the
refrigerator (2°C to 8°C)
Why:
•Customization (API conc, appropriate base
ingredient)
•Freshness and Stability
•Patient Specificity
Benefits:
•melasma treatment
•Hyperpigmentation
•Anti-Aging
•Acne Treatment

14. Diclofenac Powder
•Analog of GABA
(under stability testing)
•First line for dystonia
•Initial Dose: 0.3 to 1.0 mg/kg
•Skeletal muscle relaxant for multiple
sclerosis patients and paediatric
patients with cerebral palsy
•Spinal cord injuries and other spinal
cord diseases
•In CP paediatric patients, tablet
crushing is forced occasionally so that
oral baclofen can be administered via an
enteral or nasogastric tube

15. • Available in oral, topical
and sublingual forms
when prepared
extemporaneously
• Blocks aldosterone, aiding
in sodium/water excretion
while retaining potassium.
and has anti-androgenic
effects
• Used for hypertension,
heart failure, and edema,
PCOS, hirsutism and acne
• Side effects include
hyperkalemia, dizziness,
GI upset, and breast
tenderness
• Avoided in pregnancy
due to potential fetal risks
Spironolactone Captopril
• All previous AND IV
suspensions when oral not
feasible
• Inhibits angiotensin-
converting enzyme (ACE),
reducing blood pressure
by dilating blood vessels.
• Used for hypertension,
heart failure, and diabetic
nephropathy
• Side effects include cough,
hyperkalemia, dizziness,
and angioedema.
• Avoided in pregnancy due
to potential harm to the
fetus.

16. Spironolactone Captopril
• Oral suspensions:
1-25 mg/mL
• Topical
formulations:
2-5%
• Sublingual:
25-100 mg.
• Oral solutions:
1-5 mg/mL
• Sublingual
tablets/powder
: 6.25-25 mg.

17. THANK YOU
ANY
QUESTIONS?

18. OUR
REFERENCE
S
● Name of Pharmacist: Muhammad Awais
● Email Address: awais.imran.9120@gmail.com
● Pharmacy License no: 05-352-0063-054185P
● Extemporaneously compounded medicines - PMC
● Preparation of extemporaneous oral liquid in the
hospital pharmacy
● Extemporaneous Compounding: Selective
Pharmacists with Separate Skill - PMC
● Frequency of paediatric patients administered
extemporaneous preparations at a Swedish university
hospital: a registry-based study comparing two study-
years, 10 years apart
● Stability Study of Baclofen in an Oral Powder Form
Compounded for Pediatric Patients in Japan
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