The document provides instructions for preparing calamine lotion. Calamine lotion contains calamine, zinc oxide, bentonite, sodium citrate, liquefied phenol, glycerine, and rose water. The ingredients are triturated together and glycerine is added to produce a 100ml lotion. Lotions are liquid or semi-liquid preparations containing active ingredients suspended in an aqueous or emulsified vehicle and are applied to unbroken skin without friction. Calamine lotion is a protective and mild antiseptic used to soothe and protect the skin.

1. Exp. No. 12
To prepare and submit calamine
lotion.

2. Reference(s)
• Gaud R.S., Gupta G.D.; Practical pharmaceutics; I
edition reprint 2009; S. K. Jain for CBS Publishers
and distributors Pvt. Ltd. New Delhi; page no. 105
• Jain N.K., Sharma S.N.; A Text Book Of
Professional Pharmacy; V edition reprint 2014; M.
K. Jain for Vallabh Prakashan Delhi; page no 234
• Mehta R.M.; Dispensing Pharmacy; IV edition
reprint 2014; M. K. Jain for Vallabh Prakashan
Delhi; page no. 166

3. Requirements
• Calamine, zinc oxide, bentonite, sodium
citrate, liquefied phenol, glycerine, rose water

4. Theory
• Lotions are liquid or semi-liquid preparations that
contain one or more active ingredients in an
appropriate vehicle.
• Lotions may contain antimicrobial preservatives
and other appropriate excipients, such as
stabilizers.
• Lotions are intended to be applied to the
unbroken skin without friction.
• Lotions are suspensions of solids in an aqueous
medium. Some lotions are, in fact, emulsions or
solutions

5. Formula
Ingredients Quantity Uses
Calamine 15g Astringent, soothing agent
Zinc oxide 5g Astringent, protective agent
Bentonite 3g Suspending agent
Sodium citrate 0.5ml Buffering agent, chelating
agent,
Liquefied phenol 0.5ml Antiseptic, preservative
Glycerine 5 ml Humectant
Rose water, sufficient to
produce
100ml Perfumed vehicle

6. Procedure
• Prepare sodium citrate solution in 70mlrose
water.
• Triturate calamine, zinc oxide and bentonite
with citrate solution.
• Add liquefied phenol and mix.
• Add glycerine and sufficient rose water to
produce 100ml.

7. • Category: Protective
• Storage: It should be stored in a well closed
container because zinc oxide gradually
converts into zinc carbonate due to
atmospheric carbon dioxide
• Uses: Protective and mild antiseptic

8. • Result

9. Label for Preparation

10. Video link
• https://youtu.be/EBX5_A6qikA
• https://youtu.be/z0MXmN-4mEI
• https://youtu.be/cCO5vS0iLyI