Excess maize in diet and pellagra
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Pellagra may also occur as the result of a variety of (relatively rare) conditions affecting tryptophan metabolism and as a side-effect of the number of drugs that inhibit tryptophan metabolism. In alcoholics, it is unclear whether pellagra is the result of an impairment of tryptophan and the niacin metabolism directly attributable to alcohol, or whether it reflects general under nutrition among the people who obtain a considerable proportion on their energy needs from alcohol, and hence have the low intake of (nutrient rich) foods(Goldberger et al.,1922a). SYMPTOMS The major symptoms of pellagra are dermatitis, dementia, and diarrhea. This is because niacin deficiency is most noticeable in the body parts with high rates of cell turnover, such as the skin or gastrointestinal tract (Goldberger et al., 1923).
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Cellulosic bmw
Although 76-90% of the BMW is non-hazardous and harmless as any of the other municipal waste, the remaining 10-26% is hazardous to humans or animals and deleterious to environment. Inappropriate handling of the BMW may have serious public health consequences and the significant impact on the environment. Major hospitals contribute substantially to the quantum of generation of the BMW. Smaller hospitals, the nursing homes, clinics, the pathological laboratories and blood banks also have major contribution to BMW. The common methods adopted for the BMW disposal are incineration and land filling. However, these methods are mainly considered more expensive and less ecofriendly due to their main negative impact on the environment
Corona virus current scenario (theoretical outlook)
Corona virus(COVID-19) is RNA virus. Which has proved to be pandemic.It causes respiratory disease called Severe Acute Respiratory Syndrome(SARS). Currently it is a deadly disease which is killing hundreds of people day by day from late 2019 to till date. There is only few studies regarding the corona virus infection in animals. Studies are still progressing to find remedies like variolation, RNA silencing or boosting human interferon’s to decrease the affect of the disease.
Kite turbine for wind energy
INTRODUCTION
As people have seen, the giant industrial wind farms, small household wind turbines, and also everything in between are erecting all over the places. In 2012, the electricity capacity from the wind power in the total electric capacity is about 7.2% in EU, 2.0% in China, and 3.6% in US. Nevertheless, most people agree that wind energy should claim much greater share of the future energy supply. For eg:-, the United States is working on an ambitious target of 21% total electricity capacity by 2030. Indeed, wind energy is one of the fastest growing energy sources today and also in the foreseeable future. However, findings a suitable site to build the wind farm or simply set up the wind turbine is not always easy. The wind must be strong and must be consistent; the tower cannot obstruct the view; and the noise cannot disturb the local residence. Due to the fast growth of the population, it is aggrandizingly difficult to find a suitable place that is proper for a wind turbine yet will not interfere with the people’s everyday life (Srensen et al., 2002).
Electro hybrid system
INTRODUCTION
A lot of basic concepts, technologies and pioneering solutions aiming on very high power densities were mainly developed within the last 20 years. Sometimes this is denoted as the mechatronic system integration or simply as mechatronics. Besides many of the technical aspects, the movings within the value chain represent the great challenge in this process. This is because traditionally defined between electronic device and the power module manufacturers, electronics assemblers, and the metalworking industry will blur or slowly disappear. However, the pressure to go this path increases. If one thinks, e.g., about the hybrid drive as an upgrade option for conventional passenger cars, one is directly faced with the lack of construction space as one of the main serious problems (Alkuhayli et al., 2012).
Combined effect of walking and forest
The growing interest in the environmental stress has been accompanied by a rapid accumulation of evidence indicating that the environment can elicit substantial stress in people living in urban environments. Furthermore, it is widely conceived that the natural environment can enhance human health. There have been several questionnaire studies and investigations on the psychological effects of forest environments. A previous study found an enhancement of the positive emotions among subjects who were shown pictures of natural environments. Moreover, other researches have also found that forest environments improve the psychological wellbeing of people
Liquid biopsies
As the techniques that have enabled us to analyses and assess a biopsy become ever more sophisticated, we have realised the limitations of looking at the single snap-shot of the tumour. This single-biopsy bias was highlighted in which it was mainly demonstrated that a portion taken from different parts of a primary tumour and its metastases showed and proved extensive intertumoural and intratumoural evolution. This tumoural heterogeneity mainly highlights the difficulty of dictating a therapeutic course of action based on the single biopsy, as it is likely to underestimate the ramification of the genomic landscape of the tumour (Chomczynski et al., 2016).Having established that there is mainly considerable tumour heterogeneity, taking multiple biopsies from the patients‘ primary tumour and the metastases would seem to be the most obvious next step. There are so much difficulties in obtaining the tissue biopsy— including the discomfort suffered by the patient, the inherent clinical risks to the patient
Rivivna humilis berry extract as fungal source
The introduction of the mankind had marked the continuous exploitation of the plants as organisms and their products for the pharmacological prospects and key features (Guha et al., 1999). In most of the agronomic domains around the globe, the conventional modes of the treatment are still in exercise and also in upcoming research (Srivastava et al., 2003).
These approaches most commonly exploit the various dynamics and much specific potential and applications of plant extracts (Bonde et al., 2007) . The distinctions of the first and foremost large-scale screening of the green plants evaluate and also assess the antimicrobial activity of 2,300 plants (Nautiyal et al., 1984).
Dyeing is an ancient and traditional art which predates written records. It was practised specifically during the Bronze Age in Europe (Sreeremya, 2016). Conventional dyeing techniques encompassed sticking plants to fabric or rubbing crushed pigments into cloth.
Isolation and morphological characterization of bacterial flora from monsoon ...
The Indian summer monsoon ranges from June to September, also known as the southwest monsoon season is majorly governed by the huge land–sea thermal contrast. It encompasses large arrayed convective cloud bands over the south Asian monsoon domain, which extend more than 100 days. The rainfall received specifically in the subcontinent from these cloud bands diverted into evaporation, runoff, and the infiltration. The infiltrated water is held in the soil as soil moisture. Therefore, there is consistent relation of the soil moisture with rainfall, even though the relation is non-linear (Cox et al., 2000). Atmospheric boundary layer plays a pivotal role in regulating weather and the climate by exchanging large amount of surface water and energy with the overlying atmosphere. In the soil population, fungi population also contributes to the biofilm making (Sreeremya, 2019).
Preliminary assessment of microbes isolated from indoor money plant
Epipremnum aureum (Linden and Andre) Bunting is also availed as the scientific name of the prosperity plant by many and also considered as synonym of Scindapsus aureus. Besides money plant, other names availed commonly for this plant are Pothos, the Silver Vine, Devil's Ivy and Solomon Island's Ivy (Chetan et al., 2011). This plant is specifically native to Southeastern Asia and New Guinea (Chan et al., 1998). Crassula ovatais is also termed as jade plant, friendship tree, the lucky plant or Money Plant sometimes referred to as the money tree. Pachira aquatic is also referred as the money tree or Money plant. Hence, there is confusion, exists in the nomenclature. In Asia, however, Scindapsus aureus is grown as money plant in the houses (Srivasatava et al., 2011). It sometimes may be grown both as a trailer and a climber. It is the scrambler shrub and it can climb by the means of aerial roots over the trees and the plants which hook over the tree branches
Scoville heat unit
The “hot” in hot peppers is due to the capsaicin (C18H27NO3), a colorless, odorless oil-like compound found in the fruit of a plant that is a close relative of the tomato. Capsaicin is primarily seen in the membrane that holds the seeds. These plants are seen in the Americas and were brought to Europe by explorer Christopher Columbus who has mistakenly thought they were a relative of the black pepper (the plant one get pepper from). To distinguish them from the black pepper plant, hot peppers are generally called chili peppers, or just plain chilis in many parts of the world. Capsaicin is also seen, in smaller amounts, in other spices, such as oregano, cinnamon, and cilantro (Kawabata et al., 2006).
Cattle urine as an efficient nutrient medium
Lately, a number of studies are being carried out to develop the cheap techniques to produce useful products from microalgae not only due to its ability to generate value-added chemicals. Although, extensive work is being achieved on the product on of biochemicals from the algae and its biomass, (single-cell protein, the animal feed, biodiesel, pigments and drugs) but still the costlier when compared to normal plant products, which obstruct the large- scale applications of algae industry . Since media constituents requires the expensive operation cost and therefore limits its availability at the larger scale as well as boosting its final product cost (Crielly et al., 1994). Sustainability issues impact on the cultivation of the algal biomass for its key, on one hand, the nitrogen fertilizer manufacturing process is energy-demanding and causes major greenhouse gas emissions, on the other hand the world’s phosphorus reserves are depleting due to the phosphate rock mining (Girija et al., 2013).
Artificial seed encapsulation of chilly seeds
The demand for the artificial seed technology started after the discovery of the somatic embryo production in different plant species in vitro (Gray et al., 1991). Artificial seeds, which are also known by the other names such as “synseeds”, are firstly described by Murashige.
He delineated artificial seeds as “an encapsulated single somatic embryo” (Redenbaugh et al., 1986). Artificial seed was later defined as “a somatic embryo that is engineered for the practical use in commercial plant production”
( Redenbaugh et al.,1988). Considering the recalcitrance to somatic embryogenesis in some plant species, the concept of the artificial seeds was later extended to be the encapsulation of the range of in vitro-derived propagules (Onishi et al., 1994) .
Social anxiety
Mean age of onset is in the mid-teens, and the onset after age 30 is uncommon. Although prevalence of SAD is greatest among young adults, for many sufferers the disorder is quiet chronic. Prevalence is also greater among persons who are much less educated and those who are single. Additionally, SAD is usually accompanied by comorbid disorders, such as mainly depression, substance abuse, or other anxiety disorders, which can further impair functioning. SAD has been shown in many studies and investigations to be associated with impairment and disability. SAD increases the risk of dropout from school, the work absence, unemployment, and utilization of social welfare, causing significant financial costs for the society.
When compared with persons with no psychiatric disorder, having SAD is allied with financial dependency and increased rates of suicidal ideation.
Significance of sprouted broccoli
Neuro inflammation plays a pivotal role in the regulation of aging, Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), multiple sclerosis (MS), stroke, depression, dementia, and metabolic anomalies such as hypertension and diabetes. Neuro inflammation is also the pathogenic hallmark of the aging-related neurodegenerative conditions. Therefore, anti-inflammatory strategies and analysis could be efficient prophylactic and therapeutic management strategies for the number of central nervous system (CNS) disorders. CNS disorders may develop owing to the chronic microglial activation. Glial cells, specifically microglia, are immune cells in the CNS that are responsible for the maintenance of normal homeostasis as well as the repair after injury in the brain.
Ruminal fluid
The ruminant fluid was identified as the potential source for biogas producing microorganisms
such as hydrolytic, acidogens, acetogens, and methanogens. The analysis of ruminal fluid and its
key examination are carried out, because it is an immense source of major beneficial organisms
(Chuba, L, 2009). The observation of rumen fluid is done to analyse the activity of the ruminant
fore stomach as well as the diagnosis of diseases of the fore stomach. This is a task for which the
veterinary technician may be quite availed providing that they are familiar with ruminant
anatomy as well as physiological considerations regarding handling and testing of collected
fluids. Subacute ruminal acidosis is a common health and production problem in the cattle
industries of the United States. It is a risk wherever cattle are fed diets rich in starch in order to
achieve high rates of growth or milk production
Pancreaticoduodenectomy or whipple procedure
The classic technique of PD consists of the en-bloc removal of the distal segment of the stomach (antrum), the first and the second portions of the duodenum, specifically the head of the pancreas, the distal CBD, and the gallbladder. Another approach to this procedure is known as the pylorus-sparing PD. In this approach, a small segment of the duo denum is left in situ with the entire stomach to preserve the pylorus and prevent the post–gastrectomy-related symptoms and complications. The classic Whipple and the pylorus-preserving operations are associated with comparable operation times, blood loss, hospital stays, mortality, morbidity, and the incidence of delayed gastric emptying (Mathur et al., 2015). The overall long-term and the disease-free survival is comparable in both groups.
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Evaluation of antidepressant activity of clitoris ternatea in animals
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Non-respiratory Functions of the Lungs.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdf
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Excess maize in diet and pellagra
- 1. BY DR.SREEREMYA.S FACULTY OF BIOLOGY