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Genetic and Molecular
Biology
Reading Evolution’s Journal
in
...ATCG...
“Missing Information”
Why is evidence important to a theory?
Evidence
supports a
claim.
“Missing Information”
Why is evidence important to a theory?
Scientific Evidence:
Experimental Results,
Repeatable,
Independently
Observable.
Facts - things that
verifiably occur in nature.
Evidence of Evolution
What’s up Chuck?
There’s still
something
missing!
1953
Watson and
Crick
DNA the chemical
code for all life.
The Code
Evidence in the chemistry of life
Evidence in the chemistry of life
“All living cells use information coded in DNA and RNA to
carry information from one generation to the next and to direct
protein synthesis. The genetic code is nearly identical in
almost all organisms, including bacteria, yeast, plants, fungi,
and animals.”
Identify the differences in the amino acid sequence
below. Closer related species will have fewer
differences.
GENETIC EVIDENCE
Count the differences and find out!
*Coelacanth is type of lobed-fined fish - our common ancestor from the sea; Fugu is a type of ray-
finned fish - not our closest ancestor from the sea - a type of puffer-fish actually; Mouse is a mammal
that eats cheese (you know - like a mouse).
Who is more closely related to theWho is more closely related to the
mouse?mouse?
Fugu
Mouse
CoelacanthMouse to Coelacanth =
6 differences
Mouse to Fugu = 8
differences
Not tested on this...just extra cool
stuff
Not tested on this...just extra cool
stuff
Article from
HEREDITY
2006
“Building
Divergent Body
Plans with
similar Genetic
Pathways”
http://www.readcube.com/articl
es/10.1038/sj.hdy.6800872
HOX
genes
Mendel’s work 1856-1863
REDISCOVERED in 1900’s
REDISCOVERED in 1900’s
Darwin, nor anyone else from his
time, had any clue about the
mechanics of heredity. Mendel
was first to quantify it but his work
went unnoticed until the early
1900’s.

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Evo genetic evidence_lt10

  • 1. Genetic and Molecular Biology Reading Evolution’s Journal in ...ATCG...
  • 2. “Missing Information” Why is evidence important to a theory? Evidence supports a claim.
  • 3. “Missing Information” Why is evidence important to a theory? Scientific Evidence: Experimental Results, Repeatable, Independently Observable. Facts - things that verifiably occur in nature.
  • 5. What’s up Chuck? There’s still something missing!
  • 6. 1953 Watson and Crick DNA the chemical code for all life.
  • 7. The Code Evidence in the chemistry of life Evidence in the chemistry of life “All living cells use information coded in DNA and RNA to carry information from one generation to the next and to direct protein synthesis. The genetic code is nearly identical in almost all organisms, including bacteria, yeast, plants, fungi, and animals.” Identify the differences in the amino acid sequence below. Closer related species will have fewer differences.
  • 9. Count the differences and find out! *Coelacanth is type of lobed-fined fish - our common ancestor from the sea; Fugu is a type of ray- finned fish - not our closest ancestor from the sea - a type of puffer-fish actually; Mouse is a mammal that eats cheese (you know - like a mouse). Who is more closely related to theWho is more closely related to the mouse?mouse? Fugu Mouse CoelacanthMouse to Coelacanth = 6 differences Mouse to Fugu = 8 differences
  • 10. Not tested on this...just extra cool stuff Not tested on this...just extra cool stuff Article from HEREDITY 2006 “Building Divergent Body Plans with similar Genetic Pathways” http://www.readcube.com/articl es/10.1038/sj.hdy.6800872 HOX genes
  • 11. Mendel’s work 1856-1863 REDISCOVERED in 1900’s REDISCOVERED in 1900’s Darwin, nor anyone else from his time, had any clue about the mechanics of heredity. Mendel was first to quantify it but his work went unnoticed until the early 1900’s.