7. • IgA nephropathy: common in Asians
&Caucasians
Rare Blacks
• SLE : higher among Asians, African Americans,
African Caribbeans, & Hispanic Americans
Occurs infrequently in Africa
• Kidney stones
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Race/ Ethnicity
8. Occupation
Occupation has well established effects
Accounts 4% of cancer in US
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• Textile industry
• Leather and rubber
• Painting
• Peterolium and gases
• Metalworking
Nephrolithiasis
• Cooks
• Engineering room
personnel
Bladder Ca & RCC
9. Chief Compliant
• Must be clearly defined because:
• provides the initial information
• clues to begin formulating DDx
• constant reminder to the urologist as to why the
patient initially sought care
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10. History of Present Illness/HPI
• The duration
• Severity
• Chronicity
• Periodicity and
• Degree of disability are important considerations
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12. 1.Is the hematuria gross or microscopic?
Gross hematuria
• Significant pathology
• Increase with the degree of hematuria
• Can’t miss underlying pathology!
• Microscopic hematuria a negative
urologic evaluation
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Cont’d...
13. 2. At what time during urination the hematuria
does occur?
Initial Hematuria
Hematuria at the beginning of urination
Urethral source
2o to inflammation
Least common form of Hematuria
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Cont’d...
14. Total Hematuria
Hematuria occurring throughout voiding
Originate from the bladder, ureters, or kidneys
The commonest form of Hematuria
Terminal hematuria
Hematuria the end of voiding
Bladder neck or prostatic urethra
Bladder neck contracts, squeezing out the last
amount of urine
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Cont’d...
15. 3. Is the hematuria associated with pain?
•Usually painless
•Painful if inflammation or obstruction
Cystitis
•Painful urinary irritative symptoms
•Pain is usually not worsened with passage of
clots
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This helps identify the source of the hematuria!!!
16. Upper urinary tract hematuria
•Pain + hematuria usually
•results from obstruction of ureters with clots
•Passage of these clots colicky flank pain
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18. 4.Is the patient passing clots?
Significant degree of hematuria
Almost always due to extraglomerular bleeding
Probability urologic pathology
Do the clots have a specific shape?
Amorphous clots Bladder or prostatic urethral
origin
Vermiform clots Ureteric Origin
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19. • Past Medical illness
• History of similar illness
• Other diseases (e.g. Tb)
• Previous hx of surgery
• Hx of drug intake
•Family History
• Hereditary nephritis
• PCKD
• Sickle cell disease
• Malignancies
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20. Anything else you want to ask ?
A recent URTI
Recent vigorous exercise or trauma
History of a bleeding disorder or bleeding from multiple
sites due to excessive anticoagulant therapy
Cyclic hematuria in women
• suggesting endometriosis of the urinary tract
• Contamination with menstruation
Travel or residence in areas endemic for Schistosoma
haematobium or TB
Recent Diet
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24. Ear
– Sensorineural hearing loss in AS
•Weber Lateralization test
•Rinnes test Air and bone conduction
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25. Lymphoglandular System
• Supraclavicular lymphadenopathy
Most commonly prostate and testis cancer
• Inguinal lymphadenopathy
Carcinoma of the penis or urethra
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26. Abdominal Examination
Per rectal Examination/PRE/
Asymmetric areas of induration or frank nodules
are suggestive of prostate cancer
Symmetric enlargement and firmness of the prostate
are more frequent in men with benign prostatic
hyperplasia (BPH)
Tender----Prostatitis
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27. Genito-Urinary System
• Suprapubic Tenderness
• CVAT
• Bimanual Palpation
Assessing the regional extent of a bladder tumor
or other pelvic mass
The bladder is palpated between the abdomen
and the vagina in the female or the rectum in the
male
Define areas of :
Induration
Mobility
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usually not painful
unless associated with inflammation or obstruction
Thus, patients with cystitis and secondary hematuria may experience painful urinary irritative symptoms but the pain is usually not worsened with passage of clots. More commonly, pain in association with hematuria usually results from upper urinary tract hematuria with obstruction of the ureters with clots. Passage of these clots may be associated with severe, colicky flank pain similar to that produced by a ureteral calculus, and this helps identify the source of the hematuria
Usually, if the patient is passing clots, they are amorphous and of bladder or prostatic urethral origin
the presence of vermiform (wormlike) clots, particularly if associated with flank pain, identifies the hematuria as coming from the upper urinary tract with formation of vermiform clots within the ureter.
Although inflammatory conditions may result in hematuria, all patients with hematuria, except perhaps young women with acute bacterial hemorrhagic cystitis, should undergo urologic evaluation. Older women and men who present with hematuria and irritative voiding symptoms may have cystitis secondary to infection arising in a necrotic bladder tumor or, more commonly, flat carcinoma in situ of the bladder. The most common cause of gross hematuria in a patient older than age 50 years is bladder cancer.
Sterile pyuria with hematuria, which may occur with renal tuberculosis, analgesic nephropathy and other interstitial diseases.
Cyclic hematuria in women that is most prominent during and shortly after menstruation, suggesting endometriosis of the urinary tract Contamination with menstrual blood is always a possibility, and should be ruled out by repeating the urinalysis when menstruation has ceased.
Supraclavicular lymphadenopathy may be seen with any GU neoplasm, most commonly prostate and testis cancer; inguinal lymphadenopathy may occur secondary to carcinoma of the penis or urethra