Long-term periodic monitoring of cardiovascular function in unobtrusive way has been a challenge in sensor research lately. This work presents the investigation of the method for pulse arrival time (PAT) estimation using body composition scales. It employs the electrocardiogram and the impedance plethysmogram (IPG) which are recorded from palm and plantar electrodes already integrated into body composition scales. Four subjects were involved in the experiment. The IPG was acquired from a single-foot and foot-to-foot and compared to the reference method — photoplethysmography. The range of correlation coefficient obtained in different methods varied from 0.7 to 0.94 showing that small PAT variations can be tracked using the IPG signals. Such results suggest that body composition scales could be supplemented with additional parameter for the assessment of arterial stiffness. This function will make them truly multi-parametric device for periodic health monitoring at home
Project Report on ECG Transmitter using Agilent ADS (Advance System Design)Manu Mitra
In 1996, Intellidesign Pty Ltd (then IntelliMed) was approached by a cardiologist to design an ECG Holter monitor. This original device was a two or three lead, single channel ECG device, which could continuously record for a maximum of one hour. Additionally, the device had Polar Chest Strap capabilities for the added functionality as a Heart Rate monitor. The device could operate in four different modes: 1-hour ECG Recording Mode, in which the device would record one continuous hour of near diagnostic quality ECG trace during exercise; Event Recording Mode, in which the device would record up to 60, one minute segments around a recorded event, over a period of up to 24 hours; Heart rate Recording Mode, in which the unit would have the capacity to record up to 24 hours of heart rate information; and ECG Telemetry Mode, in which the unit would transmit, via a Radio Frequency (RF) link, a real-time ECG signal to a receiver unit. The purpose of this project is to design ECG transmitter using the software Agilent ADS.
Acquiring Ecg Signals And Analysing For Different Heart AilmentsIJERA Editor
This paper describes and focuses on acquiring and identification of cardiac diseases using ECG waveform in LabVIEW software, which would bridge the gap between engineers and medical physicians. This model work collects the waveform of an affected person. The waveform is analyzed for diseases and then a report is sent to the doctor through mail. Initially the waveforms are collected from the person using EKG sensor with the help of surface electrodes and the hardware controlled by MCU C8051, acquires ECG and also Phonocardiogram (PCG) synchronously and the waveform is sent to the PC installed with LabVIEW software through DAQ-6211. The waveform in digital format is saved and sent to the loops containing conditions for different diseases. If the waveform parameters coincide with any of the looping statements, particular disease is indicated. Simultaneously the patient PCG report is also collected in a separate database containing all information, which will be sent to the doctor through mail.
As per the Syllabus of EC453- Biomedical Instrumentation of the BVM Engineering College, EC Department, the topic -1 slides developed. This is just a basic overview of biomedical instrumentation.
The basics of the biomedical equipments, ECG, EMG, EEG, Pace maker, Defibrillator, Lasik, Robotics Surgery, ICU, Bio-Telemetry system, Plasma Medicine, etc are discussed and the video link of the topics are also given.
The anatomy of heart, ECG, sensors, transducers, heart sound, blood pressure, blood volume, blood flow, circulatory systems are discussed related to engineering concepts.
The measurements related to cardiovascular, plethysmography, blood pressure measurements, volume measurements, blood flow measurements, echo cardio, doppler and its block diagrams are discussed. Supporting video links are also attached with.
Designing a 3-Lead Cost Effective ECG Recording Glove for Home Monitoring bioejjournal
The EKG Glove is a wearable glove-based device on which all the necessary electrodes are pre-positioned hence the patient simply inserts his right hand into the glove and properly position the glove his chest to
record a standard ECG. It is the first, lead wire free, simultaneous, and fully diagnostic ECG recording
system in Pakistan with easy, natural and almost automatic placement of the electrodes, hence eliminating the difficulty of lead wire entanglement and electrode misplacement.
Project Report on ECG Transmitter using Agilent ADS (Advance System Design)Manu Mitra
In 1996, Intellidesign Pty Ltd (then IntelliMed) was approached by a cardiologist to design an ECG Holter monitor. This original device was a two or three lead, single channel ECG device, which could continuously record for a maximum of one hour. Additionally, the device had Polar Chest Strap capabilities for the added functionality as a Heart Rate monitor. The device could operate in four different modes: 1-hour ECG Recording Mode, in which the device would record one continuous hour of near diagnostic quality ECG trace during exercise; Event Recording Mode, in which the device would record up to 60, one minute segments around a recorded event, over a period of up to 24 hours; Heart rate Recording Mode, in which the unit would have the capacity to record up to 24 hours of heart rate information; and ECG Telemetry Mode, in which the unit would transmit, via a Radio Frequency (RF) link, a real-time ECG signal to a receiver unit. The purpose of this project is to design ECG transmitter using the software Agilent ADS.
Acquiring Ecg Signals And Analysing For Different Heart AilmentsIJERA Editor
This paper describes and focuses on acquiring and identification of cardiac diseases using ECG waveform in LabVIEW software, which would bridge the gap between engineers and medical physicians. This model work collects the waveform of an affected person. The waveform is analyzed for diseases and then a report is sent to the doctor through mail. Initially the waveforms are collected from the person using EKG sensor with the help of surface electrodes and the hardware controlled by MCU C8051, acquires ECG and also Phonocardiogram (PCG) synchronously and the waveform is sent to the PC installed with LabVIEW software through DAQ-6211. The waveform in digital format is saved and sent to the loops containing conditions for different diseases. If the waveform parameters coincide with any of the looping statements, particular disease is indicated. Simultaneously the patient PCG report is also collected in a separate database containing all information, which will be sent to the doctor through mail.
As per the Syllabus of EC453- Biomedical Instrumentation of the BVM Engineering College, EC Department, the topic -1 slides developed. This is just a basic overview of biomedical instrumentation.
The basics of the biomedical equipments, ECG, EMG, EEG, Pace maker, Defibrillator, Lasik, Robotics Surgery, ICU, Bio-Telemetry system, Plasma Medicine, etc are discussed and the video link of the topics are also given.
The anatomy of heart, ECG, sensors, transducers, heart sound, blood pressure, blood volume, blood flow, circulatory systems are discussed related to engineering concepts.
The measurements related to cardiovascular, plethysmography, blood pressure measurements, volume measurements, blood flow measurements, echo cardio, doppler and its block diagrams are discussed. Supporting video links are also attached with.
Designing a 3-Lead Cost Effective ECG Recording Glove for Home Monitoring bioejjournal
The EKG Glove is a wearable glove-based device on which all the necessary electrodes are pre-positioned hence the patient simply inserts his right hand into the glove and properly position the glove his chest to
record a standard ECG. It is the first, lead wire free, simultaneous, and fully diagnostic ECG recording
system in Pakistan with easy, natural and almost automatic placement of the electrodes, hence eliminating the difficulty of lead wire entanglement and electrode misplacement.
DESIGNING A 3-LEAD COST EFFECTIVE ECG RECORDING GLOVE FOR HOME MONITORINGbioejjournal
The EKG Glove is a wearable glove-based device on which all the necessary electrodes are pre-positioned hence the patient simply inserts his right hand into the glove and properly position the glove his chest to ecord a standard ECG. It is the first, lead wire free, simultaneous, and fully diagnostic ECG recording
system in Pakistan with easy, natural and almost automatic placement of the electrodes, hence eliminating the difficulty of lead wire entanglement and electrode misplacement.
Evaluating ECG Capturing Using Sound-Card of PC/Laptopijics
The purpose of the Evaluating ECG capturing using sound-card of PC/Laptop is provided portable and low
cost ECG monitoring system using laptop and mobile phones. There is no need to interface microcontroller
or any other device to transmit ECG data. This research is based on hardware design,
implementation, signal capturing and Evaluation of an ECG processing and analyzing system which attend
the physicians in heart disease diagnosis. Some important modification is given in design part to avoid all
definitive ECG instrument problems faced in previous designs. Moreover, attenuate power frequency noise
and noise that produces from patient's body have required additional developments. The hardware design
has basically three units: transduction and conditioning Unit, interfacing unit and data processing unit.
The most focusing factor is the ECG signal/data transmits in laptop/PC via microphone pin. The live
simulation is possible using SOUNDSCOPE software in PC/Laptop. The software program that is written
in MATLAB and LAB-View performs data acquisition (record, stored, filtration) and several tasks such as
QRS detection, calculate heart rate.
Hemodynamic Assessment Series by Transonic -- Part 1: PV Loop Case StudyInsideScientific
Session 3 of our PV Loop Webseries was a case study review in Pressure-Volume loops, sponsored by Transonic. Guest speakers, Dr. Craig Emter, Dr. Robert Hamlin, Dr. Timothy Hacker, and Dr. Filip Konecny discussed the role of PV loops in HFpEF, Drug-Discovery and Safety Testing, Right Ventricular PV Loops in Pulmonary HTN, and Medical Device Testing using LVADs as an example. The over riding topic linking all four of these short lectures was how PV loops work in concert with other techniques, permitting complete hemodynamic evaluation.
Case Study 1: Integrating Coronary Vascular & Myocardial Function in Mini-swine with Heart Failure (an aortic banding model of HFpEF) -- Dr. Craig Emter
Case Study 2: What are the properties of this compound? (reviewing the value and need for PV loops in drug-discovery and safety testing in pharmaceutical research labs) -- Dr. Robert Hamlin
Case Study 3: The Utility of Right Ventricular PV Loops (a mouse model of Pulmonary Arterial Hypertension that transitions from compensatory RV remodeling to right heart failure) Dr. Timothy Hacker
Case Study 4: Synergy of Pressure-Volume Technology with Left Ventricular Assisted Devices (why PV loops are valuable when conducting LVAD testing in both pre and post operation situations)
Classification of Arrhythmia from ECG Signals using MATLABDr. Amarjeet Singh
An Electrocardiogram (ECG) is defined as a test
that is performed on the heart to detect any abnormalities in
the cardiac cycle. Automatic classification of ECG has
evolved as an emerging tool in medical diagnosis for effective
treatments. The work proposed in this paper has been
implemented using MATLAB. In this paper, we have
proposed an efficient method to classify the ECG into normal
and abnormal as well as classify the various abnormalities.
To brief it, after the collection and filtering the ECG signal,
morphological and dynamic features from the signal were
obtained which was followed by two step classification
method based on the traits and characteristic evaluation.
ECG signals in this work are collected from MIT-BIH, AHA,
ESC, UCI databases. In addition to this, this paper also
provides a comparative study of various methods proposed
via different techniques. The proposed technique used helped
us process, analyze and classify the ECG signals with an
accuracy of 97% and with good convenience.
In this American Physiological Society (APS) webinar produced in partnership with ADInstruments, DeWayne Townsend, DVM, PhD and Adam Goodwill, PhD discuss how to collect and analyze quality pressure-volume loop data.
Specifically, they discuss why PV loops are considered the gold standard for measuring cardiac function in vivo, what equipment is required to collect PV loop data, and how to minimize variability in your data. The focus of the webinar is on data analysis – DeWayne and Adam demonstrate how to analyze load-independent measures of function and discuss what the data mean.
Key Learning Objectives Include:
– Why PV loops? What are the alternatives (e.g. echo, MRI, etc.) and how do PV loops compare?
– Why is the Starling effect important?
– Load independent measures: what are they and how are they measured? How are data analyzed and what do they mean?
– Equipment basics: what do you need to record PV loop data?
– What causes variability and how do you mitigate it?
A Noninvasive Alternative to +dP/dtmax: Peak Aortic Blood AccelerationInsideScientific
During this webinar, sponsored by Indus Instruments, Dr. Anilkumar Reddy of the Baylor College of Medicine shows how peak acceleration of blood flow velocity in the ascending aorta can be used as a surrogate, noninvasive measurement to evaluate cardiac contractility. Importantly, this technique enables serial measurements in the same animal, leading to reduced animal-to-animal variability, fewer subjects and shorter data collection times.
Specifically, Dr. Reddy presents preliminary findings from his validation studies in mice, where peak aortic acceleration and peak +dP/dt were compared. He highlights the utility of the Doppler method showing how measurements of mitral inflow and myocardial perfusion capacity through coronary flow reserve can be used to noninvasively assess diastolic function. Furthermore, he presents specific examples of noninvasive cardiac measurements and discuss how they scale in translational research from mice to mammals.
Key topics covered during this webinar included:
- Evaluating cardiac contractility using peak aortic acceleration
- Investigating cardiac relaxation using mitral peak early velocity to peak atrial velocity ratio
- Interpreting myocardial perfusion capacity through coronary flow reserve at baseline and with disease or other conditions
- How Doppler Flow Velocity measurements can be used in translational research from mice to mammals
Cardiac Pacemakers: Function,
Troubleshooting, and Management
Part 1 of a 2-Part Series
Siva K. Mulpuru, MD, Malini Madhavan, MBBS, Christopher J. McLeod, MBCHB, PHD, Yong-Mei Cha, MD,
Paul A. Friedman, MD
Conduction system of the heart
Action potential of cardiac tissues
Cardiac cell architecture
Blood supply of conduction tissue of heart
Influence of autonomic nervous system on heart
Conduction of impulse
Cardiac cycle
Electrical vector
Recording and presentation of Electrical activity of the heart
Parts and components of a normal ECG
SA node
Ionic Basis of Electrical Activity in Pacemaker Cells
Secondary/ Latent pacemaker
How Atrial impulse is transmitted?
AV node
Bundle of His
Purkinje fibers/ventricular myocardium
International Journal of Engineering Research and Applications (IJERA) is an open access online peer reviewed international journal that publishes research and review articles in the fields of Computer Science, Neural Networks, Electrical Engineering, Software Engineering, Information Technology, Mechanical Engineering, Chemical Engineering, Plastic Engineering, Food Technology, Textile Engineering, Nano Technology & science, Power Electronics, Electronics & Communication Engineering, Computational mathematics, Image processing, Civil Engineering, Structural Engineering, Environmental Engineering, VLSI Testing & Low Power VLSI Design etc.
DESIGNING A 3-LEAD COST EFFECTIVE ECG RECORDING GLOVE FOR HOME MONITORINGbioejjournal
The EKG Glove is a wearable glove-based device on which all the necessary electrodes are pre-positioned hence the patient simply inserts his right hand into the glove and properly position the glove his chest to ecord a standard ECG. It is the first, lead wire free, simultaneous, and fully diagnostic ECG recording
system in Pakistan with easy, natural and almost automatic placement of the electrodes, hence eliminating the difficulty of lead wire entanglement and electrode misplacement.
Evaluating ECG Capturing Using Sound-Card of PC/Laptopijics
The purpose of the Evaluating ECG capturing using sound-card of PC/Laptop is provided portable and low
cost ECG monitoring system using laptop and mobile phones. There is no need to interface microcontroller
or any other device to transmit ECG data. This research is based on hardware design,
implementation, signal capturing and Evaluation of an ECG processing and analyzing system which attend
the physicians in heart disease diagnosis. Some important modification is given in design part to avoid all
definitive ECG instrument problems faced in previous designs. Moreover, attenuate power frequency noise
and noise that produces from patient's body have required additional developments. The hardware design
has basically three units: transduction and conditioning Unit, interfacing unit and data processing unit.
The most focusing factor is the ECG signal/data transmits in laptop/PC via microphone pin. The live
simulation is possible using SOUNDSCOPE software in PC/Laptop. The software program that is written
in MATLAB and LAB-View performs data acquisition (record, stored, filtration) and several tasks such as
QRS detection, calculate heart rate.
Hemodynamic Assessment Series by Transonic -- Part 1: PV Loop Case StudyInsideScientific
Session 3 of our PV Loop Webseries was a case study review in Pressure-Volume loops, sponsored by Transonic. Guest speakers, Dr. Craig Emter, Dr. Robert Hamlin, Dr. Timothy Hacker, and Dr. Filip Konecny discussed the role of PV loops in HFpEF, Drug-Discovery and Safety Testing, Right Ventricular PV Loops in Pulmonary HTN, and Medical Device Testing using LVADs as an example. The over riding topic linking all four of these short lectures was how PV loops work in concert with other techniques, permitting complete hemodynamic evaluation.
Case Study 1: Integrating Coronary Vascular & Myocardial Function in Mini-swine with Heart Failure (an aortic banding model of HFpEF) -- Dr. Craig Emter
Case Study 2: What are the properties of this compound? (reviewing the value and need for PV loops in drug-discovery and safety testing in pharmaceutical research labs) -- Dr. Robert Hamlin
Case Study 3: The Utility of Right Ventricular PV Loops (a mouse model of Pulmonary Arterial Hypertension that transitions from compensatory RV remodeling to right heart failure) Dr. Timothy Hacker
Case Study 4: Synergy of Pressure-Volume Technology with Left Ventricular Assisted Devices (why PV loops are valuable when conducting LVAD testing in both pre and post operation situations)
Classification of Arrhythmia from ECG Signals using MATLABDr. Amarjeet Singh
An Electrocardiogram (ECG) is defined as a test
that is performed on the heart to detect any abnormalities in
the cardiac cycle. Automatic classification of ECG has
evolved as an emerging tool in medical diagnosis for effective
treatments. The work proposed in this paper has been
implemented using MATLAB. In this paper, we have
proposed an efficient method to classify the ECG into normal
and abnormal as well as classify the various abnormalities.
To brief it, after the collection and filtering the ECG signal,
morphological and dynamic features from the signal were
obtained which was followed by two step classification
method based on the traits and characteristic evaluation.
ECG signals in this work are collected from MIT-BIH, AHA,
ESC, UCI databases. In addition to this, this paper also
provides a comparative study of various methods proposed
via different techniques. The proposed technique used helped
us process, analyze and classify the ECG signals with an
accuracy of 97% and with good convenience.
In this American Physiological Society (APS) webinar produced in partnership with ADInstruments, DeWayne Townsend, DVM, PhD and Adam Goodwill, PhD discuss how to collect and analyze quality pressure-volume loop data.
Specifically, they discuss why PV loops are considered the gold standard for measuring cardiac function in vivo, what equipment is required to collect PV loop data, and how to minimize variability in your data. The focus of the webinar is on data analysis – DeWayne and Adam demonstrate how to analyze load-independent measures of function and discuss what the data mean.
Key Learning Objectives Include:
– Why PV loops? What are the alternatives (e.g. echo, MRI, etc.) and how do PV loops compare?
– Why is the Starling effect important?
– Load independent measures: what are they and how are they measured? How are data analyzed and what do they mean?
– Equipment basics: what do you need to record PV loop data?
– What causes variability and how do you mitigate it?
A Noninvasive Alternative to +dP/dtmax: Peak Aortic Blood AccelerationInsideScientific
During this webinar, sponsored by Indus Instruments, Dr. Anilkumar Reddy of the Baylor College of Medicine shows how peak acceleration of blood flow velocity in the ascending aorta can be used as a surrogate, noninvasive measurement to evaluate cardiac contractility. Importantly, this technique enables serial measurements in the same animal, leading to reduced animal-to-animal variability, fewer subjects and shorter data collection times.
Specifically, Dr. Reddy presents preliminary findings from his validation studies in mice, where peak aortic acceleration and peak +dP/dt were compared. He highlights the utility of the Doppler method showing how measurements of mitral inflow and myocardial perfusion capacity through coronary flow reserve can be used to noninvasively assess diastolic function. Furthermore, he presents specific examples of noninvasive cardiac measurements and discuss how they scale in translational research from mice to mammals.
Key topics covered during this webinar included:
- Evaluating cardiac contractility using peak aortic acceleration
- Investigating cardiac relaxation using mitral peak early velocity to peak atrial velocity ratio
- Interpreting myocardial perfusion capacity through coronary flow reserve at baseline and with disease or other conditions
- How Doppler Flow Velocity measurements can be used in translational research from mice to mammals
Cardiac Pacemakers: Function,
Troubleshooting, and Management
Part 1 of a 2-Part Series
Siva K. Mulpuru, MD, Malini Madhavan, MBBS, Christopher J. McLeod, MBCHB, PHD, Yong-Mei Cha, MD,
Paul A. Friedman, MD
Conduction system of the heart
Action potential of cardiac tissues
Cardiac cell architecture
Blood supply of conduction tissue of heart
Influence of autonomic nervous system on heart
Conduction of impulse
Cardiac cycle
Electrical vector
Recording and presentation of Electrical activity of the heart
Parts and components of a normal ECG
SA node
Ionic Basis of Electrical Activity in Pacemaker Cells
Secondary/ Latent pacemaker
How Atrial impulse is transmitted?
AV node
Bundle of His
Purkinje fibers/ventricular myocardium
International Journal of Engineering Research and Applications (IJERA) is an open access online peer reviewed international journal that publishes research and review articles in the fields of Computer Science, Neural Networks, Electrical Engineering, Software Engineering, Information Technology, Mechanical Engineering, Chemical Engineering, Plastic Engineering, Food Technology, Textile Engineering, Nano Technology & science, Power Electronics, Electronics & Communication Engineering, Computational mathematics, Image processing, Civil Engineering, Structural Engineering, Environmental Engineering, VLSI Testing & Low Power VLSI Design etc.
ABOUT ECG AND PCG The electrocardiograph (ECG) is an instrument which records the electrical activity of the heart. ... ECG provides valuable information about a wide range of cardiac disorders such as the presence of an inactive part (infarction) or an enlargement (cardiac hypertrophy) of the heart muscle.
The electrocardiograph (ECG) is an instrument which records the electrical activity of the heart. ... ECG provides valuable information about a wide range of cardiac disorders such as the presence of an inactive part (infarction) or an enlargement (cardiac hypertrophy) of the heart muscle.
Phonocardiogram based diagnostic systemijbesjournal
A Phonocardiogram or PCG is a plot of high fidelity recording of the sounds and murmurs made by the
heart with the help of the machine called phonocardiograph. It has developed continuously to perform an
important role in the proper and accurate diagnosis of the defects of the heart. As usually with the
stethoscope, it requires highly and experienced physicians to read the phonocardiogram. A diagnostic
system based on Artificial Neural Networks (ANN) is implemented as a detector and classifier of heart
diseases. The output of the system is the classification of the sound as either normal or abnormal, if it is
abnormal what type of abnormality is present. In this paper, Based on the extracted time domain and
frequency domain features such as energy, mean, variance and Mel Frequency Cepstral Coefficients
(MFCC) various heart sound samples are classified using Support Vector Machine (SVM), K Nearest
Neighbour (KNN), Bayesian and Gaussian Mixture Model (GMM) Classifiers. The data used in this paper
was obtained from Michigan university website.
The PR interval is the time from the onset of the P wave to the start of the QRS complex.
It reflects conduction through the AV node.
The normal PR interval is between 120 – 200 ms (0.12-0.20s) in duration (three to five small squares).
If the PR interval is > 200 ms, first degree heart block is said to be present.
PR interval < 120 ms suggests pre-excitation (the presence of an accessory pathway between the atria and ventricles) or AV nodal (junctional) rhythm.
Electrocardiograhy (A topic in National Book Foundation Text Book for the Federal Board's Pre-Medical Students, up to their level for their Concepts and Understandings as well as the proper NOTES to have marks in Board's Exams). In'sha'Allah, they as well as Professors will Appreciate this Hectic Task of mine. It took 10 days to arrange and synchronize the material up to their Level of Understanding.
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
Similar to Estimation of Pulse Arrival Time Using Impedance Plethysmogram from Body Composition Scales (20)
CARRE EU-FP7-ICT-61440 project presentation, Oct 2016CARRE project
CARRE: Personalized patient empowerment and shared decision support for cardiorenal disease and comorbidities, FP7-ICT-61440 Project Presentation in the eHealth Forum 2016, Athens, Greece, 25-26 October 2016
Photoplethysmography-Based System for Atrial Fibrillation Detection During He...CARRE project
D. Stankevicius , A. Petrenas, A. Solosenko, M. Grigutis, T. Januskevicius, L. Rimsevicius, V. Marozas. Photoplethysmography-Based System for Atrial Fibrillation Detection During Hemodialysis. In IFMBE Proceedings, vol. 57, 14th Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON 2016), pp. 79-82, Paphos, Cyprus, 31 Mar. – 2 Apr. 2016
Towards Privacy by Design in Personal e-Health SystemsCARRE project
G. Drosatos, P. S. Efraimidis, G. Williams, E. Kaldoudi. Towards Privacy by Design in Personal e-Health Systems. In Proc. of the 9th International Conference on Health Informatics (HealthInf 2016), part of BIOSTEC, pp. 472-477, Rome, Italy, 21-23 Feb. 2016
An Ontology based Scheme for Formal Care Plan Meta-DescriptionCARRE project
E. Kaldoudi, G. Drosatos, N. Portokallidis, A. Third. An Ontology based Scheme for Formal Care Plan Meta-Description. In Proc. of the 14th Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON 2016), Paphos, Cyprus, 31 Mar. – 2 Apr. 2016
Gender Balance in EU and a Case Report of an EU Funded ProjectCARRE project
E. Kaldoudi, Gender Balance in EU and a Case Report of an EU Funded Project, Invited Talk, Special Session on Women in Medical and Biological Engineering, MEDICON 2016, Paphos, Cyprus, 2 April 2016
CARRE: Personalized patient empowerment and shared decision support for car...CARRE project
Eleni Kaldoudi
CARRE: Personalized patient empowerment and shared decision support for cardiorenal disease and comorbidities
Presentation & Demo
HealthInf 2016: 9th International Conference on Health Informatics, part of BIOSTEC, Rome, Italy, 21-23 February, 2016
Governmental and private eHealth and telemedicine initiatives in LithuaniaCARRE project
R. Kizlaitis, Governmental and private eHealth and telemedicine initiatives in Lithuania, East Europe eHealth Innovation Summit, Warsaw, 15 January 2015
Vilnius University Hospital Santariškių KlinikosCARRE project
R. Kizlaitis, Vilnius University Hospital Santariškių Klinikos – International eHealth projects, Presentation at The Royal Hospital, Oman, Muscat 30 January 2015
Extracting Intention from Web Queries– Application in eHealth PersonalizationCARRE project
G. Drosatos, A. Arampatzis and E. Kaldoudi, Extracting Intention from Web Queries - Application in eHealth Personalization, In the Proceedings of the IUPESM 2015: World Congress on Medical Physics & Biomedical Engineering, Toronto, Canada, 7-12 June, 2015.
Personalizing healthcare applications requires capturing patient specific information, including medical history, health status, and mental aspects such as behaviors, intentions, and attitudes. This paper presents a privacy-friendly system to deduce patient intentions that can be used to personalized eHealth applications. In the proposed approach patient inten-tion is deduced from web query logs via query categorization techniques. The architecture assumes a user application which conceals the user’s queries from the central system, while only relevant intentions are disclosed. The paper presents a prototype implementation of the proposed architecture to extract intentions for personalizing empowerment services for the cardiorenal patient. Emphasis is placed on identifying intentions related to travel, diet and physical exercise, as these play an important role for the daily management of cardiorenal disease.
Aggregating Educational Data for Patient EmpowermentCARRE project
N. Portokallidis, G. Drosatos, E. Kaldoudi, Aggregating Educational Data for Patient Empowerment, ELEVIT 2015: 6th Panhellenic Conference on Biomedical Technology, p. 79, Athens, Greece, 6-8 May 2015
Empowering Patients through Information Technologies - WC2015 KeynoteCARRE project
Eleni Kaldoudi, Empowering Patients through Information Technologies, Keynote Speech, IUPESM World Congress 2015, Toronto, Canada, June 7-12, 2015
Patient empowerment is about enabling the patients to be involved in managing disease and adopting and sustaining health promoting behaviors. Patient empowerment, although a popular concept, is rather ill defined. This lecture aims to elucidate the different meanings and perceptions, together with misconceptions, that surround this construct, and to discuss how patient empowerment relates to current medical methodologies, such as evidence based medicine, and other societal and organizational factors. Furthermore, the lecture will provide an overview of how information and communication technologies are employed to empower patients, with emphasis in chronic patients with comorbidities.
The discussion will first address the “who”. This includes an overview of common health problems that call for empowered patients, the types of patients that normally engage in empowering interventions and the specifics of the stakeholders who design and support such interventions.
Then we will look at the “how”. The discussion here will focus on an overview of the diverse approaches and services that have been deployed to empower patients. This will also include the span of various technologies used and, where applicable, their measured induced outcome for the patient and the health care process.
Although the “who” and “how” of patient empowerment can rather easily be discerned from a literature research, the “what” is rather more elusive. The concept of patient empowerment has emerged as a new paradigm that can help improve medical outcomes while lowering costs of treatment by facilitating self-directed behavior change. Patient empowerment has gained even more popularity since the 1990’s, due to the emergent of eHealth and its focus on putting the patient in the centre of the interest. Current literature provides systematic reviews of the area, and shows that well defined areas (or dimensions) have eventually emerged in the field: education, engagement, and control. Despite such findings, current research lacks of a structured approach towards patient empowerment. In an attempt to shed more light onto the process of empowering patients, this lecture will discuss a newly proposed holistic model of patient empowerment as a cognitive process, where we acknowledge three levels of increasing complexity and importance: awareness, participation, and control.
The lecture will conclude with a proof of concept example of using this approach to develop and evaluate empowerment services for the comorbid cardiorenal patient or the patient at risk of this condition. Open issues and challenges will be presented for discussion with the audience.
Patient Empowerment as a Cognitive ProcessCARRE project
E. Kaldoudi, N. Makris, Patient Empowerment as a Cognitive Process, In: C. Verdier, M. Bienkiewicz, A. Fred, H. Gamboa and D. Elias (Eds), The Proceedings of HealthInf 2015: 8th International Conference on Health Informatics, pp. 605-610, Lisbon, Portugal, 12-15 January, 2015
The concept of patient empowerment has emerged as a new paradigm that can help improve medical outcomes while lowering costs of treatment by facilitating self-directed behavior change. Patient empowerment has gained even more popularity since the 1990’s, due to the emergent of eHealth and its focus on putting the patient in the centre of the interest. Current literature provides systematic reviews of the area, and shows that well defined areas (or dimensions) have eventually emerged in the field. In this paper we argue that patient empowerment should be treated formally as a cognitive process. We thus propose a cognitive model that consists of three major levels of increasing complexity and importance: awareness, engagement and control. We also describe the different constituents of each level and their implications for patient empowerment interventions, focusing on interventions based on information and communication technologies. Finally, we discuss the implications of this model for the design and evaluation of patient empowerment interventions.
ICT in Medical Education: Educating and Empowering the PatientCARRE project
E. Kaldoudi, ICT in Medical Education: Educating and Empowering the Patient, Workshop on Medical Education and Research in the 21st Century, Larissa, October 9-11, 2014
CARRE project presentation - November 2013
CARRE is an EU FP7-ICT funded project with the goal to provide innovative means for the management of comorbidities (multiple co-occurring medical conditions), especially in the case of chronic cardiac and renal disease patients or persons with increased risk of such conditions.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
insect taxonomy importance systematics and classification
Estimation of Pulse Arrival Time Using Impedance Plethysmogram from Body Composition Scales
1. Estimation of Pulse Arrival Time Using
Impedance Plethysmogram from Body
Composition Scales
Birutė Paliakaitė1, Saulius Daukantas2, Andrius Sakalauskas2,
Vaidotas Marozas1,2
1Department of Electronics Engineering, Kaunas University of Technology
2Biomedical Engineering Institute, Kaunas University of Technology
April 13-15, 2015
2. Motivation
Arterial stiffness leads to the development of
cardiovascular morbidity and mortality1.
Central (aortic) stiffness:
– elderly subjects,
– end-stage renal disease,
– hypertension,
– impaired glucose tolerance.
Peripheral (lower-limbs) stiffness:
– peripheral artery disease,
– diabetic peripheral neuropathy.
1/141S. Laurent et al. Expert consensus document on arterial stiffness: methodological issues and
clinical applications. Eur. Heart J., vol. 27, no. 21, 2006.
3. Motivation
Arterial stiffness leads to the development of
cardiovascular morbidity and mortality.
Central (aortic) stiffness1:
– elderly subjects,
– end-stage renal disease,
– hypertension,
– impaired glucose tolerance.
Peripheral (lower-limbs) stiffness:
– peripheral artery disease,
– diabetic peripheral neuropathy.
1/141S. Laurent et al. Expert consensus document on arterial stiffness: methodological issues and
clinical applications. Eur. Heart J., vol. 27, no. 21, 2006.
4. Motivation
Arterial stiffness leads to the development of
cardiovascular morbidity and mortality.
Central (aortic) stiffness:
– elderly subjects,
– end-stage renal disease,
– hypertension,
– impaired glucose tolerance.
Peripheral (lower-limbs) stiffness:
– peripheral artery disease2,
– diabetic peripheral neuropathy3.
1/14
2H. Yokoyama et al. Pulse wave velocity in lower-limb arteries among diabetic patients with
peripheral arterial disease. J. Atheroscler. Thromb., vol. 10, no. 4, 2003.
3M. Edmonds et al. Blood flow in the diabetic neuropathic foot. Diabetologia, vol. 22, no. 1, 1982.
6. Background
Arterial stiffness can be characterized by the
propagation of the pulse pressure wave (PPW) along
the arterial tree.
Pulse arrival time (PAT) – the time interval between the
R-wave of the QRS complex and the particular point in
the PPW.
2/14
7. Background
Arterial stiffness can be characterized by the
propagation of the pulse pressure wave (PPW) along
the arterial tree.
Pulse arrival time (PAT) – the time interval between the
R-wave of the QRS complex and the particular point in
the PPW.
2/14
8. Background
Arterial stiffness can be characterized by the
propagation of the pulse pressure wave (PPW) along
the arterial tree.
Pulse arrival time (PAT) – the time interval between the
R-wave of the QRS complex and the particular point in
the PPW.
2/14
9. Background
Arterial stiffness can be characterized by the
propagation of the pulse pressure wave (PPW) along
the arterial tree.
Pulse arrival time (PAT) – the time interval between the
R-wave of the QRS complex and the particular point in
the PPW.
2/14
PAT
Arterial stiffness
15. Problem
Long-term periodic monitoring needed
Available devices for PPW recording
Illustrations retrieved from http://www.atcormedical.com/ and http://www.atcormedical.com/
3/14
16. Problem
Long-term periodic monitoring needed
Available devices for PPW recording:
Illustrations retrieved from http://www.atcormedical.com/ and http://www.atcormedical.com/
Operator dependent
Results rely on the placement
3/14
18. New Approach (1)
Impedance plethysmography (IPG) to determine
changing tissue volumes (e.g. blood).
ECG and IPG electrodes integrated into unobtrusive
devices (e.g. bathroom scales)
4/14
𝑹 = 𝝆
𝒍
𝑨
Illustration retrieved from OMRON HBF-510 Instruction Manual
19. New Approach (2)
The lower-body IPG signals are the sum of the local
impedances of all segments between the voltage
electrodes,
5/14
20. New Approach (2)
The lower-body IPG signals are the sum of the local
impedances of all segments between the voltage
electrodes,
5/14Illustration retrieved from O. G. Martinsen, S. Grimnes, Bioimpedance and Bioelectricity Basics,
2nd ed., London: Academic Press, 2008.
but the influence of the lower parts is
the greatest.
21. New Approach (2)
The lower-body IPG signals are the sum of the local
impedances of all segments between the voltage
electrodes,
5/14Illustration retrieved from O. G. Martinsen, S. Grimnes, Bioimpedance and Bioelectricity Basics,
2nd ed., London: Academic Press, 2008.
but the influence of the lower parts is
the greatest.
The goal of this study is to
demonstrate that PAT from the heart
to the foot can be estimated using
ECG and IPG recorded on
the bathroom scales.
22. Measurement Setup
Body composition scales (Omron)
ECG: wireless ECG transmitter (Biopac)
IPG: electrical bioimpedance unit (Biopac)
IPG: photoplethysmogram amplifier unit
(Biopac)
Illustration retrieved from OMRON HBF-510 Instruction Manual
6/14
23. Measurement Setup
Body composition scales (Omron)
ECG: wireless ECG transmitter (Biopac)
IPG: electrical bioimpedance unit (Biopac)
IPG: photoplethysmogram amplifier unit
(Biopac)
Illustration retrieved from OMRON HBF-510 Instruction Manual
6/14
24. Measurement Setup
Body composition scales (Omron)
ECG: wireless ECG transmitter (Biopac)
IPG: electrical bioimpedance unit (Biopac)
IPG: photoplethysmogram amplifier unit
(Biopac)
Illustration retrieved from OMRON HBF-510 Instruction Manual
6/14
25. Measurement Setup
Body composition scales (Omron)
ECG: wireless ECG transmitter (Biopac)
IPG: electrical bioimpedance unit (Biopac)
PPG: photoplethysmogram amplifier unit
(Biopac)
Illustration retrieved from OMRON HBF-510 Instruction Manual
6/14
49. Conclusions and Future Directions
Conclusions
– PAT can be estimated by using IPG and ECG sensors, which are integrated
into body composition scales;
– PAT evaluated by the method introduced in this study correlates with
PPG-based PAT;
– single-foot and foot-to-foot PATIPG slightly differs.
Future directions
– testing of the custom-made system;
– development of the algorithm for the calculation of PAT;
– a wider group of subjects with different health status.
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50. Acknowledgment
This work was partly supported by the projects
“Promotion of Student Scientific Activities” (VP1-3.1-
ŠMM-01-V-02-003) from the Research Council of
Lithuania and CARRE (No.611140) funded by the
European Community 7th Framework Programme.