This document discusses epilepsy, including its definition, types of seizures, causes, symptoms, and treatment options. Epilepsy is a disorder caused by disturbed nerve cell activity in the brain, which leads to seizures. There are two main types of seizures - partial seizures, which affect only one part of the brain, and generalized seizures, which affect the whole brain. Some common causes include genetic factors, trauma, tumors, infections, and drug or alcohol withdrawal. Symptoms vary depending on the type of seizure but may include muscle stiffness, twitching, loss of awareness, and falling. Treatment typically involves medications like valproic acid, topiramate, and levetiracetam to control seizures.

1. EPILEPSY
JVSR SARMA
GUNTUR - ASM

2. WHAT IS EPILEPSY? AND TYPES OF
EPILEPSY…
A disorder in which nerve cell activity in the brain is disturbed, causing seizures.
DEFINITION:-
The occurrence of transient paroxysms of excessive or uncontrolled
discharges of neurons, which may be caused by a number of different
etiologies, leading to epileptic seizures.
ALSO CALLED SEIZURES.

3. PARTIAL SEIZURES
• PARTIAL SEIZURES.
• COMPLEX PARTIAL SEIZURES.
GENERALISED SEIZURES
• MYOCLONIC SEIZURES.
• TONIC SEIZURES
• TONIC – CLONIC SEIUZURES.
• ABSENCE SEIZURES
• TYPICAL
• ATYPICAL
TYPES OF SEIZURES:-

4. CAUSES FOR EPILEPSY
• INHERITED CAUSES:
 INHERITED GENETIC
 ACQUIRED:
1. TRAUMA
2. NEURO SURGERY
3. METABOLIC INFECTIONS
4. TUMOR
5. TOXIC DISORDERS
 CONGENITAL: IN BORN ERROR OF METABOLISM.
 WITHDRAWL OF DRUGS: ALCOHOL, OTHER ANTI EPILEPTICS

5. SYMPTOMS OF PARTICAL
SEIZURES
ALTERATIONS TO SENSE OF TASTE,
SMELL, SIGHT, HEARING, OR TOUCH
DIZZINESS
TINGLING AND TWITCHING OF
LIMBS
SYMPTOMS OF GENERALIZED
SEIZURES
• TONIC SEIZURES :CAUSE MUSCLE STIFFNESS.
• ATONIC SEIZURES :LEAD TO LOSS OF MUSCLE
CONTROL AND CAN MAKE YOU FALL DOWN
SUDDENLY.
• CLONIC SEIZURES: ARE CHARACTERIZED BY
REPEATED, JERKY MUSCLE MOVEMENTS OF
THE FACE, NECK, AND ARMS.
• MYOCLONIC SEIZURES: CAUSE SPONTANEOUS
QUICK TWITCHING OF THE ARMS AND LEGS.
SYMPTOMS OF EPILEPSY

6. TREATMENT OPTIONS:-
• DEPENDS UPON SEVERITY OF THE SYMPTOMS MANY DRUGS ARE USING TO
TREAT.
• Eg:- VALPROIC ACID, TOPIRAMATE,LEVITERACETAM, ETC..,,,

7. VALPORATE CHRONO[CONTROLLED RELEASE SODIUM VALPROATE AND VALPROIC ACID 200/300/500 MG TABLETS]
A BROAD SPECTRUM MOOD STABILIZER
Greater efficacy & faster onset of action when
compared to Lithium
Safe & better tolerated in Manic Disorder
Low dose valproate useful in the treatment of
Cyclothymia & milder rapid 2cycling Bipolar Disorders

8. • SELECT THE CUSTOMERS WHO ARE MORE TREATING EPILEPTIC PATIENTS.
• DO THOROUGH RCPA.
• CONVEY THE CLEAR DETAILED TALK.
• HIGHLIGHT THE BRAND WITH INDICATIONS.
• REGULAR VISITS.
• ENSURE TO MAKE THE PRODUCT AVAILABILITY AT THE RETAIL CHEMIST.
POSITIONING OF BRAND

9. VALPORATE CHRONO [PRICE PACK COMPOSITION]
BRAND COMPOSITION PACK PRICE
Valporate Chrono 200CR Sodium Valproate IP 133mg+Valporic Acid USP 58mg 10's 31.63
Valporate Chrono 300CR Sodium Valproate IP 200mg+Valporic Acid USP 87mg 10's 41.80
Valporate Chrono 500CR Sodium Valproate IP 333mg+ Valporic Acid USP 145mg 10's 76.49

10. DIRECT COMPETITORS
BRAND COMPANY NAME PRICE
ENCORATE CHRONO-
MG
SUN 106.8
VALTEC CR CIPLA 86.66
EPILEX CHRONO TAB ABBOTT 106.88
VALPRID CR MICRO 106.8
VALRATE CR TAB IPCA 103.89

11. THANK YOU
SIR..
JVSR SARMA..
GUNTUR - ASM