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Neurosurgery, Skull Base Surgery
 Definition
 Embryonic derivative originated by remains of elements of ectodermal origin during
the closure of the neural tube between 3rd and 5th SDG
 Epidemiology
 1% from all intracranial and 7% from all angle tumors,
 3rd-5th decade of life
 Classification
 Diagnosis
 Clinical syndrome according to lesion site
www.neurologiasegura.net
10 cases
45%
23%
7%
8%
8%
8%
brain tumors associated
epidermoid cyst Neurinoma
chordoma Metastasis
Meningioma Carcinoma
n=21
TIPICA
70%
TIC
12%
ATIPICA
3%
OCC
2%
EM
1%
Tumors
8%
Multiple Esclerosis
Postraumatic
Miastenia Gravis
Postherpetic
Arnold Chiari
n=270
Distribution by etiology n=270
Trigeminal Neuralgia Syndrome Operated Cases
www.neurologiasegura.net
Trigeminal Neuralgia and Brain Tumors
www.neurologiasegura.net
0
13
25
38
50
ene'11 abr'11 jul'11 oct'11 ene'12 abr'12 jul'12 oct'12 ene'13 abr'13 jul'13 oct'13 ene'14 abr'14 jul'14 oct'14 ene'15 abr'15 jul'15 oct'15
treated operated
3%0%
0%
2%
5%
1%
2%
1%
3%
0%
1%
0%
60%
1%
0%
0%
5%
1%
0%
4%
4%
7%
Argentina Bolivia
Canada Chile
Colombia Costa Rica
Ecuador El Salvador
España Francia
Guatemala Honduras
México Nicaragua
Panama Paraguay
Perú Puerto Rico
Uruguay USA
Venezuela No Esp.
geography and demography
from January 2010 up today
Our Telemed Experience
www.neurologiasegura.net
0
30
60
90
20
10´s 20´s 30´s 40´s 50's 60´s 70´s 80´s 90´s
1
8
34
27
52
31
26
7
1
24
3
31
73
60
103
67
49
16
2
Distribution by age (decades)
January 2010 - January 2015
Our Experience
54%
45%
1%
DERECHO IZQUIERDO BILATERAL
>70y/o = 16%
21- 30 = 3
31 - 40 = 4
41 – 50 = 1
51 – 60 = 1
>61= 1
<40y/o = 70% ECyst
TN Clinical Course
24%
29%
22%
8%
17%
Timing n=776
<3
3 to 6
7 to 10
11 to 14
>15
YEARS
0
15
30
45
60
1 2 3 4 5 6
1 2 3 4 5 7 8 9 10 12 13 14 15 16 17 18 …
Advanced
Non pharmacological response
• Pharmacological phase
Chronic
Complex
Complicated
All Trigeminal Neuralgia
www.neurologiasegura.net
 Imaging diagnosis
 CT
 Lobulated low-density intracranial lesion with or without calcifications
 MRi
 Heterogeneous T1-T2 hypo-hyperintense multilobed extra-axial lesion
 Histopathological analysis
www.neurologiasegura.net
www.neurologiasegura.net
www.neurologiasegura.net
Our surgical and non surgical trigeminal
neuralgia cases n=776
Tumor removal microsurgical resection (8%)
- E. Cyst 10 cases
Microvascular decompression (23%)
Percutaneous ablative procedures
– Radiofrequency gangliolysis (9%)
– Glycerol rhizolysis (1%)
– Ganglion balloon compression (<1%)
Stereotactic radiosurgery (3,2%)
– GK/CK
– LINAC-based
Peripheral ablative procedures
– Peripheral branch neurectomy
– Alcohol neurolysis
Open destructive procedures
– Partial sensory rhizotomy
– Subtemporal ganglionectomy
(Frazier-Spiller procedure)
– Trigeminal bulbar nucleus thermoablation (<1%)
5
43
116
280
Our Surgical Trigeminal Neuralgia
www.neurologiasegura.net
Our Complications from all MVD
Author Year n= CSF V VII VIII Death Inf Rec
Breeze 1982 52 2% 17% 15% 11% 0
Van Loveren 1982 23 13% 9%
Apfelbaum 1983 406 1% 3% 1%
Kolluri 1984 72 11% 19% 0
Piatt 1984 103 2% 1% 1% 8% 1%
Zorman 1984 125 4% 2% 3% 0
Bederson 1989 166 4% 3% 5% 5% 0
Klun 1992 220 0 0.5% 0.5% 4.5%
Sun 1994 61 7% 3% 6% 0
Barker 1996 1204 0.2% 1% 0.5% 1% 0.2%
Kondo 1997 281 7%
Revuelta 2006 668 nd nd nd nd nd 0,2%
Segura 2015 270 1.48% 0.37% 0.74% 0.74% 0 1.48%
0.74%
11%
4%
Trigeminal Neuralgia
XIX CONGRESO DE LA
SOCIEDAD DE CIRUGIA NEUROLOGICA
DE OCCIDENTE
Homenaje Dr. Edgar Nathal-Vera
20 al 23 de Julio de 2016
Isla Navidad, México

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Epidermoid cyst at the 2nd Yemeni Neurosurgical Conference 2017 (A2017 0517)

  • 2.  Definition  Embryonic derivative originated by remains of elements of ectodermal origin during the closure of the neural tube between 3rd and 5th SDG  Epidemiology  1% from all intracranial and 7% from all angle tumors,  3rd-5th decade of life  Classification  Diagnosis  Clinical syndrome according to lesion site www.neurologiasegura.net
  • 3. 10 cases 45% 23% 7% 8% 8% 8% brain tumors associated epidermoid cyst Neurinoma chordoma Metastasis Meningioma Carcinoma n=21 TIPICA 70% TIC 12% ATIPICA 3% OCC 2% EM 1% Tumors 8% Multiple Esclerosis Postraumatic Miastenia Gravis Postherpetic Arnold Chiari n=270 Distribution by etiology n=270 Trigeminal Neuralgia Syndrome Operated Cases www.neurologiasegura.net Trigeminal Neuralgia and Brain Tumors
  • 4. www.neurologiasegura.net 0 13 25 38 50 ene'11 abr'11 jul'11 oct'11 ene'12 abr'12 jul'12 oct'12 ene'13 abr'13 jul'13 oct'13 ene'14 abr'14 jul'14 oct'14 ene'15 abr'15 jul'15 oct'15 treated operated 3%0% 0% 2% 5% 1% 2% 1% 3% 0% 1% 0% 60% 1% 0% 0% 5% 1% 0% 4% 4% 7% Argentina Bolivia Canada Chile Colombia Costa Rica Ecuador El Salvador España Francia Guatemala Honduras México Nicaragua Panama Paraguay Perú Puerto Rico Uruguay USA Venezuela No Esp. geography and demography from January 2010 up today Our Telemed Experience
  • 5. www.neurologiasegura.net 0 30 60 90 20 10´s 20´s 30´s 40´s 50's 60´s 70´s 80´s 90´s 1 8 34 27 52 31 26 7 1 24 3 31 73 60 103 67 49 16 2 Distribution by age (decades) January 2010 - January 2015 Our Experience 54% 45% 1% DERECHO IZQUIERDO BILATERAL >70y/o = 16% 21- 30 = 3 31 - 40 = 4 41 – 50 = 1 51 – 60 = 1 >61= 1 <40y/o = 70% ECyst
  • 6. TN Clinical Course 24% 29% 22% 8% 17% Timing n=776 <3 3 to 6 7 to 10 11 to 14 >15 YEARS 0 15 30 45 60 1 2 3 4 5 6 1 2 3 4 5 7 8 9 10 12 13 14 15 16 17 18 … Advanced Non pharmacological response • Pharmacological phase Chronic Complex Complicated All Trigeminal Neuralgia www.neurologiasegura.net
  • 7.  Imaging diagnosis  CT  Lobulated low-density intracranial lesion with or without calcifications  MRi  Heterogeneous T1-T2 hypo-hyperintense multilobed extra-axial lesion  Histopathological analysis
  • 8.
  • 12.
  • 13. Our surgical and non surgical trigeminal neuralgia cases n=776 Tumor removal microsurgical resection (8%) - E. Cyst 10 cases Microvascular decompression (23%) Percutaneous ablative procedures – Radiofrequency gangliolysis (9%) – Glycerol rhizolysis (1%) – Ganglion balloon compression (<1%) Stereotactic radiosurgery (3,2%) – GK/CK – LINAC-based Peripheral ablative procedures – Peripheral branch neurectomy – Alcohol neurolysis Open destructive procedures – Partial sensory rhizotomy – Subtemporal ganglionectomy (Frazier-Spiller procedure) – Trigeminal bulbar nucleus thermoablation (<1%) 5 43 116 280 Our Surgical Trigeminal Neuralgia www.neurologiasegura.net
  • 14. Our Complications from all MVD Author Year n= CSF V VII VIII Death Inf Rec Breeze 1982 52 2% 17% 15% 11% 0 Van Loveren 1982 23 13% 9% Apfelbaum 1983 406 1% 3% 1% Kolluri 1984 72 11% 19% 0 Piatt 1984 103 2% 1% 1% 8% 1% Zorman 1984 125 4% 2% 3% 0 Bederson 1989 166 4% 3% 5% 5% 0 Klun 1992 220 0 0.5% 0.5% 4.5% Sun 1994 61 7% 3% 6% 0 Barker 1996 1204 0.2% 1% 0.5% 1% 0.2% Kondo 1997 281 7% Revuelta 2006 668 nd nd nd nd nd 0,2% Segura 2015 270 1.48% 0.37% 0.74% 0.74% 0 1.48% 0.74% 11% 4% Trigeminal Neuralgia
  • 15. XIX CONGRESO DE LA SOCIEDAD DE CIRUGIA NEUROLOGICA DE OCCIDENTE Homenaje Dr. Edgar Nathal-Vera 20 al 23 de Julio de 2016 Isla Navidad, México

Editor's Notes

  1. % total (%permanent) BSAER monitoring in 1980’s