Endocrine and metabolic shock.pptx
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Endocrine shock can involve a combination of hypovolaemic, cardiogenic, and distributive shock. It can be caused by hypo- or hyperthyroidism and adrenal insufficiency. Hypothyroidism causes shock due to disordered vascular and cardiac responses to catecholamines, leading to low cardiac output and bradycardia. Adrenal insufficiency presents with vague symptoms like weakness and fatigue, while acute adrenal crisis causes vomiting, abdominal pain, and hypovolemic shock. Diabetic ketoacidosis can induce shock through hypovolemia and sepsis as hyperglycemia causes fluid and electrolyte loss. Metabolic shock occurs when the body breaks down carbohydr
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- 1. Endocrine & Metabolic shock BHAVANA RAJANNA 89 A
- 3. Endocrine shock may present as a combination of hypovolaemic, cardiogenic and distributive shock. Causes of endocrine shock include hypo- and hyperthyroidism andadrenal insufficiency. Hypothyroidism causes a shock result of disordered vascular and cardiac responsiveness to circulating catecholamines. Cardiac output fallsbecause of low inotropy and bradycardia. There may also be an associatedcardiomyopathy.Thyrotoxicosis may cause a high-output cardiac failure.
- 5. Adrenal insufficiency Adrenal insufficiency crisis An adrenal crisis is a life-threatening condition in which your adrenal glands don't make enough cortisol. Causes include damage to your adrenal glands and other stressors. Symptoms include abdominal pain, fatigue and weakness. Healthcare providers can diagnose an adrenal crisis with different blood tests. Adrenal insufficiency usually presents with vague symptoms such as weakness, fatigue, anorexia, weight loss, and hyperpigmentation as the primary symptoms. Acute adrenal crisis can manifest with vomiting, abdominal pain, and hypovolemic shock.
- 7. Hypothyroidism Hypothyroidism happens when the thyroid gland doesn't make enough thyroid hormone. This condition also is called underactive thyroid. Hypothyroidism may not cause noticeable symptoms in its early stages. Symptoms of an underactive thyroid • tiredness. • being sensitive to cold. • weight gain. • constipation. • depression. • slow movements and thoughts. • muscle aches and weakness. • muscle cramps.
- 8. How does hypothyroidism cause shock? Hypothyroidism causes muscle relaxation and the isovolumetric relaxation and contraction time becomes prolonged and MPI increases indicating systolic and diastolic dysfunction [8]. Only when Cardiac dysfunction is severe, cardiac out put can be decreased enough to cause cardiogenic shock
- 11. Can diabetic ketoacidosis cause shock? Without insulin, your body begins to break down fat in attempt to get the energy it needs, a process that ultimately results in a dangerous buildup of acids, known as ketones, in your bloodstream. When this happens, your body can go into shock, and the acid buildup causes swelling in the brain. Shock in DKA is a combination of hypovolemia and sepsis. To differentiate between the two is difficult and most of the time it may be a combination of hypovolemia and sepsis. Hyperglycemia acts as an osmotic diuretic, causing severe fluid and electrolyte losses, leading to hypovolemic shock if untreated. Individuals with severe DKA may lose nearly 500 mEq of Na+, Cl−, and K+, along with approximately 7 L of water in 24 hr.
- 13. What causes metabolic shock? It forms when the body breaks down carbohydrates to use for energy when oxygen levels are low. It can be caused by: Cancer. Carbon monoxide poisoning.