This document discusses e-innovation in healthcare procurement through translational research projects at Hospital Sant Pau in Barcelona. It provides examples of current and planned projects including a dysphagia tele-rehabilitation program. It advocates for a request for research to results methodology using living labs to test innovations with citizens before implementation. The document concludes by describing the role of the Sant Pau Knowledge Center and accountable care organizations in driving innovation through multidisciplinary collaboration between researchers, medical professionals, businesses and users.