The document discusses how Cython can be used to easily reduce runtimes by up to 3 orders of magnitude. It provides examples showing how applying Cython techniques like declaring types and using NumPy arrays reduced a Pandas apply function runtime from 175ms to 1ms and a convolution runtime from 3310ms to 13.6ms. The document encourages typing variables, matching Python and C types, using Jupyter's Cython magic, and keeping Cython optimization in mind during design to take advantage of these performance gains.