The document discusses the typical lifecycle that pharmaceutical drugs undergo, including pre-clinical trials, initial registration, clinical trials, production, marketing, supply chain management, and post-marketing surveillance. It then provides detailed information on proper procedures for taking medications, including storage, dosing, interactions, and safety. Finally, it outlines signs and symptoms of use and long-term effects for various habit-forming drugs like stimulants, opioids, hallucinogens, and inhalants.

1. Drug Lifecycle

2. Ingeneral,thePharmaceuticalindustry productpasses throughthefollowinglifecycle phases.Onabroadlevel,
thelifecyclehasthefollowingstages.
Pre-Clinical
Phase
Initial
Registration
Clinical
Trials
Drug
Production
Marketing
of Drug
Supply Chain
Management
Post-Marketing
Survey
Drug Lifecycle

3. Drug Lifecycle

4. •DO follow the exact dose and schedule prescribed by your doctor.
•DO ask your doctor about any possible side effects to watch for, and report any that you experience.
•DO ask your doctor about all over-the-counter drugs, prescription drugs, supplements, or natural remedies
that you are taking or want to take.
•DO talk with your doctor about over-the-counter drugs, prescription drugs, supplements, or natural remedies
if you are pregnant, planning to become pregnant, or breastfeeding. Some medications or supplements may
not be safe during these times.
•DO ask your doctor or pharmacist how to take your medicine properly (i.e., with or without food?, with or
without milk?, with extra water?).
•DO tell your doctor about past problems you've had with drugs, such as rashes, indigestion, dizziness, or
appetite loss.
•DO keep a daily record of the drugs you are taking.
•DO review your drug record with each of your doctors at each visit, and when any doctor prescribes a new
medicine.
•DO ask your pharmacist for large print if you cannot read the label.
•DO check the expiration date and throw out any expired medications.
•DO call your doctor right away if you have any problems with your medicine.
•DO plan for refills so that you don't run out.
Procedure
for
Taking
Medication
Do’s

5. Procedure
for
Taking
Medication
Dont’s
•DO NOT stop taking a prescription drug unless your doctor says it is
okay.
•DO NOT take more or less than the amount prescribed.
•DO NOT mix alcohol and medicine unless your doctor specifically says
it's okay.
•DO NOT take medications prescribed for someone else.
•DO NOT let anyone else take medications prescribed for you.
•DO NOT crush tablets unless you check with your doctor or pharmacist.
Some medications (eg, long-acting formulations) have special coating and
cannot be crushed.

6. •Know that heat, air,
light, and moisture may
damage your medicine.
•Store your medicines in a
cool, dry place. For
example, store it in your
dresser drawer or a
kitchen cabinet away
from the stove, sink, and
any hot appliances. You
can also store medicine in
a storage box, on a shelf,
or in a closet.
•If you are like most people,
you probably store your
medicine in a bathroom
cabinet. But the heat and
moisture from your shower,
bath, and sink may damage
your medicine. Your
medicines can become less
potent, or they may go bad
before the expiration date.
•Pills and capsules are
easily damaged by heat
and moisture. Aspirin
pills break down into
vinegar and salicylic acid.
This irritates the stomach.
•Always keep medicine in
its original container.
•Take the cotton ball out
of the medicine bottle.
The cotton ball pulls
moisture into the bottle.
•Ask your pharmacist
about any specific storage
instructions.
•Always store your
medicine out of reach and
out of sight of children.
•Store your medicine in
a cabinet with a child
latch or lock.
How to Store Medicines at Home

7. Damaged medicine may
make you sick. Do not take:
•Medicine that has changed
color, texture, or smell, even
if it has not expired
•Pills that stick together, are
harder or softer than normal,
or are cracked or chipped
Do not use Damaged Medicine
How to Store Medicines at Home

8. Get rid of old Medicines
Check the expiration date on your
medicine. Throw out medicines that
are out of date.
Do not keep old or unused medicine
around. It goes bad and you should
not use it.
Do not flush your medicine down the
toilet. This is bad for the water
supply.
To throw away medicine in the trash,
first mix your medicine with
something that ruins it, such as coffee
grounds or kitty litter. Put the entire
mixture in a sealed plastic bag.
You can also bring unused medicines
to your pharmacist.
Use community "drug give back"
programs if they are available.
How to Store Medicines at Home

9. Do not keep medicine in the glove
compartment of your car. Medicine
can get too hot, cold, or wet there.
If you are taking an airplane, keep
your medicine in your carry-on
luggage. To help with security at the
airport:
•Keep medicine in the original
bottles.
•Ask your health care provider for a
copy of all your prescriptions. You
may need this in case you lose, run
out, or damage your medicine.
•If you have diabetes, ask your provider
for a letter explaining that you have
diabetes and providing a list of all your
supplies. You are allowed to carry your
medicine, blood glucose meter, and
lancet device on a plane.
Traveling With Medicine
How to Store Medicines at Home

10. Rules
for
Storing
Eye
Drops
1.Always wash your hands first before administering eye drops.
1.Shake the bottle if indicated on the label. If the bottle has been refrigerated, warm it between your
hands to room temperature.
1.Gently clean the eyelids if they are crusty with discharge by wiping the lid from the inner corner
to the outer corner with the eye closed using with a cotton ball dampened with warm water.
1.Tilt back the head, or lie down, and look upward. Using the thumb and index finger, gently
pinch and pull the lower eyelid downward to form a pocket.
1.Place the eye drop or drops into the pouch formed in the lower lid, not directly into the eye. If an
eye ointment is used, place a 1/4 inch line of ointment into the lower lid pouch. Be careful that the
dropper or ointment tube does not touch the eye.
1.Close your eye gently for 1 to 3 minutes or as instructed by the doctor to allow the medication to be
absorbed. Some doctors recommend pressing the finger against the inner corner of the eye to keep the
medication from going into the tear duct.
1.If another drop of eye medication is needed, wait at least 5 to 10 minutes before administering the second
eye drop so the first drop will not be washed out of the eye. The small pouch formed by the lower lid will
only hold one drop at a time, and extra drops will either flow into the tear duct (and out of the eye) or down
the face.

11. •Check the label on your eye drop
or ointment to see if refrigeration
is necessary.
•Always recap the bottle or tube
immediately after use. Never wipe
or rinse the tip of the dropper to
avoid contamination.
•Many eye medications cause a
slight stinging sensation after
instillation. Tell your doctor if this
sensation lasts more than a minute
or two.
•Eye ointments cause a blurring of
vision. This is normal and should
go away in a few minutes.
•Never wear contact lenses while
using eye drops or ointments
unless instructed to do so by your
doctor.
•If you are told to use an eye drop
and an eye ointment at the same
time, use the eye drop first, wait a
few minutes, and then use the
ointment.
Rules
for
Storing
Eye
Drops

12. Drug Addiction
•Feeling that you must use
the drug regularly —
daily or even several
times a day
•Having intense urges for
the drug that block out
any other thoughts
•Over time, needing more
of the drug to get the
same effect
•Taking larger amounts of
the drug over a longer
period than you intended
•Making certain that you
maintain a supply of the
drug
•Spending money on the
drug, even though you
can't afford it
•Not meeting obligations
and work responsibilities,
or cutting back on social
or recreational activities
because of drug use

13. •Continuing to use the drug,
even though you know it's
causing problems in your life or
causing you physical or
psychological harm
•Doing things to get the drug
that you normally wouldn't do,
such as stealing
•Driving or doing other risky
activities when you're under the
influence of the drug
•Spending a good deal of time
getting the drug, using the drug
or recovering from the effects of
the drug
•Failing in your attempts to
stop using the drug
•Experiencing withdrawal
symptoms when you attempt to
stop taking the drug
Drug Addiction

14. •A sense of euphoria or feeling "high"
•A heightened sense of visual, auditory and taste
perception
•Increased blood pressure and heart rate
•Red eyes
•Dry mouth
•Decreased coordination
•Difficulty concentrating or remembering
•Slowed reaction time
•Anxiety or paranoid thinking
•Cannabis odor on clothes or yellow fingertips
•Major cravings for certain foods at unusual times
Habit
Forming
Drugs:
Signs
and
symptoms
of
use
can
include;

15. •Decreased mental
sharpness
•Poor performance at
school or at work
•Ongoing cough and
frequent lung infections
Long-term use is often associated with;

16. Habit Forming Drugs: Barbiturates, benzodiazepines and hypnotics
•Drowsiness •Slurred speech
•Lack of
coordination
•Irritability or
changes in mood
•Problems
concentrating or
thinking clearly
•Memory problems
•Involuntary eye
movements
•Lack of inhibition
•Slowed breathing
and reduced blood
pressure
•Falls or accidents •Dizziness

17. Habit Forming Drugs: Meth, cocaine and other stimulants
•Feeling of happy
excitement and too
much confidence
•Increased alertness
•Increased energy and
restlessness
•Behavior changes or
aggression
•Rapid or rambling
speech
•Larger than usual
pupils, the black circles
in the middle of the eyes
•Confusion, delusions
and hallucinations
•Irritability, anxiety or
paranoia
•Changes in heart rate,
blood pressure and body
temperature
•Nausea or vomiting
with weight loss
•Poor judgment
•Nasal congestion and
damage to the mucous
membrane of the nose (if
snorting drugs)
•Mouth sores, gum
disease and tooth decay
from smoking drugs
("meth mouth")
•Insomnia
•Depression as the drug
wears off

18. Habit Forming Drugs: Hallucinogens
•A feeling of being
separated from your
body and surroundings
•Hallucinations
•Problems with
coordination and
movement
•Aggressive, possibly
violent behavior
•Involuntary eye
movements
•Lack of pain sensation
•Increase in blood
pressure and heart rate
•Problems with thinking
and memory
•Problems speaking
•Poor judgment
•Intolerance to loud
noise
•Sometimes seizures or
coma

19. Habit Forming Drugs: Inhalants
•Possessing an inhalant
substance without a
reasonable explanation
•Brief happy excitement •Behaving as if drunk
•Reduced ability to keep
impulses under control
•Aggressive behavior or
eagerness to fight
•Dizziness
•Nausea or vomiting
•Involuntary eye
movements
•Appearing under the
influence of drugs, with
slurred speech, slow
movements and poor
coordination
•Irregular heartbeats •Tremors
•Lingering odour of
inhalant material
•Rash around the nose
and mouth

20. Habit Forming Drugs: Opioid painkillers
•A sense of feeling
"high"
•Reduced sense of pain
•Agitation, drowsiness
or sedation
•Slurred speech
•Problems with
attention and memory
•Pupils that are smaller
than usual
•Lack of awareness or
inattention to
surrounding people
and things
•Problems with
coordination
•Depression
•Confusion •Constipation
•Runny nose or nose
sores (if snorting
drugs)
•Needle marks (if
injecting drugs)