This dissertation presents research on two new samples of active galactic nuclei (AGN): 1) The HRX-BL Lac sample, which is the largest homogeneous sample of BL Lac objects to date, consisting of 77 X-ray selected BL Lac objects identified from a correlation of X-ray and radio sources. Redshifts are known for 81% of the sample. Several peculiar objects were discovered, including the brightest known BL Lac object. 2) A sample of Seyfert II galaxies identified through optical spectroscopy, consisting of 49 objects. The luminosity function of Seyfert II galaxies is derived and compared to other samples. X-ray observations are also used to search for additional Seyfert II galaxies.