The biomap® diversity plus panel offers a comprehensive profiling system that includes 12 systems with various primary human cell types for mechanism of action studies and safety and efficacy evaluations in autoimmune and inflammatory diseases. It features over 140 biomarker readouts and supports both single and co-culture formats for diverse biological applications. The process involves high throughput analysis using an automated database, with results typically available in 1 to 8 weeks depending on the system.

1. BioMAP® Diversity Plus Profiling
Bridging the Gap From In Vitro to In Vivo
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2. BioMAP® Diversity Plus Panel
 12 Systems include a variety of immune and tissue cell types
• Primary human vascular cells (endothelial and smooth muscle), epithelial cells (skin
and lung), fibroblasts, myofibroblasts, T cell, B cell, monocytes, macrophages
• Good blend of co-culture and single cell type BioMAP® Systems
• Format: > 140 biomarker readouts; 4-dose, single well format
• Useful for:
• Mechanism of action studies
• Covers most mechanisms represented in BioMAP Database
• Safety-related compound properties
• Efficacy-related activities for autoimmune or inflammatory disease areas
• Business terms
• Single compound profiling with Terms and Conditions, per compound pricing
• Competitive terms for ongoing profiling agreements or large studies
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3. BioMAP® Diversity Plus Panel (1-6)
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4. BioMAP® Diversity Plus Panel (7-12)
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5. BioMAP® Diversity Plus – Cell Types & Co-cultures
BioMAP Systems
Endothelial Cells
Peripheral Blood Mononuclear Cells
B cells
Bronchial Epithelial Cells
Dermal Fibroblasts
Smooth Muscle Cells
 10 primary human cell types Keratinocytes
 12 assay systems Lung Fibroblasts
• Different cell types, co-culture combinations Macrophages
• Different activation conditions – disease models
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6. BioMAP® Diversity Plus – Biology Covered
Vascular Biology
Immune Biology
Lung Biology
Skin Biology
Wound Healing
Th1 Inflammation
Th2 Responses
Th17 Biology
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7. BioMAP® Profiling – Process
Program Manager
High Throughput Lab
BioMAP
Database
Automated, Validated Proprietary Database
Specially trained staff and Analysis Software
Procedures
Compounds Report
Cell Culture Readout Assays Data Analysis
are Shipped Delivery
6-8 weeks (12 systems) 1-2 weeks
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8. BioMAP® Diversity Plus Profiling
Contact
Carmen Bryant
Program Manager
BioSeek, LLC
cbryant@bioseekinc.com
650-416-7647
Bridging the Gap From In Vitro to In Vivo
BioSeek, LLC
310 Utah, #100
South San Francisco, CA 94080