Current transformers (CTs) operate in series with the current being measured and cannot have an open secondary circuit, while potential transformers (PTs) operate in parallel across the voltage being measured and can have an open secondary circuit without damage. CTs treat the primary current as independent of the secondary circuit conditions, while PTs have primary current that depends on the secondary circuit conditions. CTs are used with low-voltage ammeters to measure high currents, and PTs are used with low-voltage voltmeters to measure high voltages.