This document summarizes a talk on "Radical Agility with Autonomous Teams and Microservices in the Cloud" given by Henning Jacobs and Jan Löffler from Zalando. It discusses how Zalando has adopted a microservices architecture and autonomous DevOps teams to manage the complexity of operating a large e-commerce business across Europe. The talk focuses on how microservices and cloud infrastructure enable faster development and system scalability while reducing dependencies between teams. It also describes Zalando's approach to DevOps, where it is treated as a "first-class entity" and teams have a high degree of autonomy.