Detox What I.Foresman

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carlyneubert

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The Liver is the Major Detoxifying Organ ,[object Object],[object Object],[object Object]

Phase I & Phase II ,[object Object],[object Object]

Imbalanced Detoxification Phase I CYP P450 Phase II Conjugation Damage to DNA, RNA, Proteins Reactive Intermediate Non-Polar Xenobiotic Inert Water-Soluble Metabolite

Detox enzyme capacity is highly variable ,[object Object],[object Object],[object Object],[object Object],[object Object]

Phase 2 ,[object Object],[object Object],[object Object]

Supportive Nutrients for Detoxification Pathways Bile Feces/stools Serum Kidneys Urine ATP glutathione glycine taurine glutamine ornithine arginine methyl donors N-acetylcysteine cysteine methionine r iboflavin (vit. B2) niacin (vit. B3) pyridoxine (vit. B6) folic acid vitamin B12 glutathione branched-chain amino acids flavonoids phospholipids Phase II [conjugation pathways] Phase I [cytochrome P450 enzymes] Activated Intermediates excretory derivatives Lipid-soluble molecule polar water-soluble ( )

Genetic Variations ,[object Object],[object Object]

Causes of Impaired Detoxication: Summary ,[object Object],[object Object],[object Object],[object Object],[object Object]

Is Detox right for you? ,[object Object],Parasite infestation Recurring headaches Bad breath Hemorrhoids Irritability Frequent colds Protruding belly Chronic constipation Frequent gas & bloating Excess weight Frequent fatigue Impaired digestion Irritable Bowel Syndrome (IBS) Candida infection

Common Signs & Symptoms Linked to Chronic Toxicant Exposure ,[object Object],[object Object],[object Object],[object Object]

Common Signs & Symptoms Linked to Chronic Toxicant Exposure ,[object Object],[object Object],[object Object],[object Object],[object Object]

Disorders Linked To Toxicant Exposure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What about chronic GI problems ,[object Object],[object Object],[object Object]

Potential Benefits of the Detoxification Program ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Biochemistry is the study of the structure and function of biological molecules such as proteins, nucleic acids, carbohydrates and lipids. Biochemistry is the study of the chemistry of living things. This includes organic molecules and their chemical reactions. Biochemistry deals with body substance like enzymes, carbohydrates, amino acids, fats, proteins, hormones, DNA, RNA, pigments etc. The major objective of biochemistry is the complete understanding of all chemical processes associated with living cells at the molecular level. Some of the objectives can be listed as follows: 1. Isolation, structural elucidation and the determination of mode of action of biomolecules. 2. Identification of disease mechanisms. 3. Study of in born errors of metabolism. 4. Study of oncogenes in cancer cells. 5. The relationship of biochemistry with the genetics, physiology, immunology, pharmacology, toxicology etc. Biochemistry is related to almost all the life sciences and without biochemistry background and knowledge, a through understanding of health and well-being is not possible.

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