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Design of enzyme inhibitors as drugs

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tabitha3
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DESIGN OF ENZYME INHIBITORS AS DRUGS By : Ms. Tabhitha K Guide : Mr. Sampath Ayyappa G, M.Pharm
ENZYMES - INTRODUCTION
ENZYME INHIBITION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
DESIGN OF SIMPLE COMPETITIVE INHIBITORS
 
 
 
 
 
DESIGN OF ALTERNATIVE SUBSTRATE INHIBITORS
 
DESIGN OF TRANSITION STATE ANALOGS
DESIGN OF MULTISUBSTRATE ANALOGS
DESIGN OF AFFINITY LABELING AGENTS ,[object Object],[object Object]
 
MECHANISM-BASED ENZYME INACTIVATORS
[object Object],[object Object],[object Object],[object Object],[object Object]
 
THANK YOU

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Design of enzyme inhibitors as drugs