Liza Kobelt has extensive research experience developing neural tissue engineering techniques. She has worked on 5 projects at the University of Washington investigating nerve regeneration, astrocyte markers, glioma drug sensitivity, islet cell function, and spinal cord injury hydrogels. Previously, she assisted with motion analysis software, bioreactor design, and neuronal differentiation projects at the University of Akron. She has published 2 papers and is preparing a manuscript on aligned hydrogels for neural tissue engineering. Kobelt has presented her work at several conferences and societies.
Presentation by Michaela TerAvest, assistant professor of Biochemistry and Molecular Biology at Michigan State University, at the MSU Bioeconomy Institute in Holland, Mich., on Mar. 16, 2016.
Presentation by Michaela TerAvest, assistant professor of Biochemistry and Molecular Biology at Michigan State University, at the MSU Bioeconomy Institute in Holland, Mich., on Mar. 16, 2016.
Research done by Mahendra Trivedi - Effect of a Biofield Treatment on Plant G...Abby Keif
Research on Trivedi Effect - The present experiments found an enhanced and significant impact of the biofield treatment on adaptive micropropagation response and callus induction of two plant species, Withania somnifera and Amaranthus dubius. For details, visit: http://works.bepress.com/mahendra_trivedi/23/
Abstract: Microbial fuel cells (MFCs) are alternative source of producing electricity, yet not commercialized but they shows production of electricity. The power produce by this experiment is limited but can be consider for future aspect. This research carried out by various samples which show positive result. , its due to metabolic activity which carried out in the anaerobic condition MFCs production of electricity is indirectly proportional to time. This can be seen in all samples. The experiment is carried out by construction of two-chamber, in which transfer of energy was carried out. The power production of the main mechanism in this experiment was by direct transfer of electrons to the electrode by bacteria growing on the electrode cyclic voltammeter. The attachment of bacteria on electrode was studied. The most bacteria which were isolated from the sample were Klebsiella pneumonia, Escherichia coli, Pseudomonas aeruginosa.
In December 2012, the Division of Undergraduate Education hosted a workgroup of faculty and administrators to create the learning outcomes and curriculum map for a Summer Academy@UK to be held in June 2014 in partnership with the CPE's GEAR UP KY Office
Research done by Mahendra Trivedi - Effect of a Biofield Treatment on Plant G...Abby Keif
Research on Trivedi Effect - The present experiments found an enhanced and significant impact of the biofield treatment on adaptive micropropagation response and callus induction of two plant species, Withania somnifera and Amaranthus dubius. For details, visit: http://works.bepress.com/mahendra_trivedi/23/
Abstract: Microbial fuel cells (MFCs) are alternative source of producing electricity, yet not commercialized but they shows production of electricity. The power produce by this experiment is limited but can be consider for future aspect. This research carried out by various samples which show positive result. , its due to metabolic activity which carried out in the anaerobic condition MFCs production of electricity is indirectly proportional to time. This can be seen in all samples. The experiment is carried out by construction of two-chamber, in which transfer of energy was carried out. The power production of the main mechanism in this experiment was by direct transfer of electrons to the electrode by bacteria growing on the electrode cyclic voltammeter. The attachment of bacteria on electrode was studied. The most bacteria which were isolated from the sample were Klebsiella pneumonia, Escherichia coli, Pseudomonas aeruginosa.
In December 2012, the Division of Undergraduate Education hosted a workgroup of faculty and administrators to create the learning outcomes and curriculum map for a Summer Academy@UK to be held in June 2014 in partnership with the CPE's GEAR UP KY Office
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"Làm Thế Nào Để Sao Chép Cách Làm Giàu?"
Developing data services: a tale from two Oregon universitiesAmanda Whitmire
While the generation or collection of large, complex research datasets is becoming easier and less expensive all the time, researchers often lack the knowledge and skills that are necessary to properly manage them. Having these skills is paramount in ensuring data quality, integrity, discoverability, integration, reproducibility, and reuse over time. Librarians have been preserving, managing and disseminating information for thousands of years. As scholarly research is increasingly carried out digitally, and products of research have expanded from primarily text-based manuscripts to include datasets, metadata, maps, software code etc., it is a natural expansion of scope for libraries to be involved in the stewardship of these materials as well. This kind of evolution requires that libraries bring in faculty with new skills and collaborate more intimately with researchers during the research data lifecycle, and this is exactly what is happening in academic libraries across the country. In this webinar, two researchers-turned-data-specialists, both based in academic libraries, will share their experiences and perspectives on the development of research data services at their respective institutions. Each will share their perspective on the important role that libraries can play in helping researchers manage, preserve, and share their data.
OM: Advanced Bio-Well Practical Hands on Training - Feb.5-6-7/2016Krishna Madappa
OM: As our global and concentrated Bio-Well community grows, so should our dedicated training.
Dr.K.Korotkov & Krishna see this as an essential educational module for creating a next generation of Bio-Well professional users.
As the software platforms continue to amplify the non-linearity and our understanding of our multi dimensional presence, we are here to ennoble a seamless interface to this evolutionary level of Human Development.
Ultimately our singular purpose is to assist all our Bio-Well users globally to be the stewards of the advanced science of Bio-Electrography and inspire a generation towards the "Sciences of Optimal Human Excellence".
Clear writing and illustrations…Clear explanations of difficult concepts…Clear communication of the ways in biochemistry is currently understood and practiced. For over 35 years, in edition after bestselling edition, Principles of Biochemistry has put those defining principles into practice, guiding students through a coherent introduction to the essentials of biochemistry without overwhelming them.
Molecular Biologist Academic CV for Industry or Private Sector Consideration Sirie Godshalk
Molecular Biologist with over thirteen years of hands-on research experience, impactful writer and presenter, dynamic leader and enthusiastic team player with an eye for great ideas and a passion to move science in new directions seeks challenging opportunities beyond the bench.
Foresight in medicine: research induced society changes in the next decadeCaroline McClain
The 2013 symposium hosts a debate among scientists, doctors, policy makers and epistemologists aimed at identifying forthcoming medical research developments likely to impact on society in the next ten years.
Personalized (or precision) medicine is the changing paradigm and will reshape service contents and delivery modalities. The main clinical areas where major progress is expected are cancer, neurodegenerative disorders, chronic obstructive pulmonary diseases, rare diseases, dysmetabolic and endocrine system related diseases.
Progress in imaging, the application of nanotechnologies, the use of robotics, wired environments and telematics, portable devices, stem cells and new materials will make personalized medicine feasible and affordable. At the same time, epigenetics, pharmacogenomics, synthetic biology will contribute extensively to change further
medicine and its social aspects, and will need to be regulated by a new bioethical approach.
In collaboration with Georgetown University Italian Research Institute and ISSNAF.
As part of "Anno Della Cultura Italiana" or Year of Italian Culture in the U.S.
PART I INTRODUCTION TO THE CELL 1
Chapter 1 Cells and Genomes 1
Chapter 2 Cell Chemistry and Bioenergetics 43
Chapter 3 Proteins 109
PART II BASIC GENETIC MECHANISMS 173
Chapter 4 DNA, Chromosomes, and Genomes 173
Chapter 5 DNA Replication, Repair, and Recombination 237
Chapter 6 How Cells Read the Genome: From DNA to Protein 299
Chapter 7 Control of Gene Expression 369
PART III WAYS OF WORKING WITH CELLS 439
Chapter 8 Analyzing Cells, Molecules, and Systems 439
Chapter 9 Visualizing Cells 529
PART IV INTERNAL ORGANIZATION OF THE CELL 565
Chapter 10 Membrane Structure 565
Chapter 11 Membrane Transport of Small Molecules and the Electrical
Properties of Membranes 597
Chapter 12 Intracellular Compartments and Protein Sorting 641
Chapter 13 Intracellular Membrane Traffic 695
Chapter 14 Energy Conversion: Mitochondria and Chloroplasts 753
Chapter 15 Cell Signaling 813
Chapter 16 The Cytoskeleton 889
Chapter 17 The Cell Cycle 963
Chapter 18 Cell Death 1021
PART V CELLS IN THEIR SOCIAL CONTEXT 1035
Chapter 19 Cell Junctions and the Extracellular Matrix 1035
Chapter 20 Cancer 1091
Chapter 21 Development of Multicellular Organisms 1145
Chapter 22 Stem Cells and Tissue Renewal 1217
Chapter 23 Pathogens and Infection 1263
Chapter 24 The Innate and Adaptive Immune Systems 1297
Glossary G: 1
Index I: 1
Tables The Genetic Code, Amino Acids T: 1
Existem diversos serviços que os pesquisadores podem usar para permanecer em contato constante com os colegas, manter-se atualizado com os resultados científicos, ou para gerenciar equipes produtivas. Entre eles estão os serviços comerciais, por exemplo, LinkedIn ou Facebook , bem como sites que foram projetados especificamente para acadêmicos, por exemplo, Academia.edu, ResearchGate, ou VIVO. Alguns sites denominados National Research Networking, NRN (Rede de Pesquisa Nacional) expõe dados institucionais de alta qualidade através de Web sites e/ou dados RDF semanticamente estruturados. Entre eles estão Elsevier SciVal Experts, Harvard Catalyst Profiles, e o sistema VIVO financiado pelo NIH. Graças a estes sistemas, os acadêmicos são identificados exclusivamente através de seus IDs institucionais e estão linkados aos artigos que publicam, às patentes de sua autoria, o financiamento que recebem, e os cursos que ministram.
There exist diverse services that researchers can use to stay in constant contact with colleagues, to keep up with scientific results, or to manage productive teams. Among them are commercial services, e.g., LinkedIn or Facebook as well as sites that were specifically designed for scholars, e.g., Academia.edu, ResearchGate, or VIVO.
A number of so called National Researcher Networking (NRN) sites expose high quality institutional data via web sites and/or semantically structured RDF data. Among them are Elsevier’s SciVal Experts, Harvard’s Catalyst Profiles, and the NIH funded VIVO system. Thanks to these systems, scholars are uniquely identified via their institutional IDs and are linked to the papers they published, the patents they authored, the funding they received, and the courses they teach.
Existen diversos servicios que los investigadores pueden utilizar para mantenerse en contacto permanente con sus colegas, para mantenerse al día con los resultados científicos, o para la gestión de equipos productivos. Entre ellos se encuentran servicios comerciales, por ejemplo, LinkedIn o Facebook, así como los sitios que fueron diseñados específicamente para los académicos, por ejemplo, Academia.edu, ResearchGate o VIVO.
Una cantidad de Sitios de la llamada National Researcher Networking (NRN) expone datos institucionales de alta calidad a través de Sitios Web y/o datos RDF estructurados semánticamente. Entre ellos se encuentran Elsevier’s SciVal Experts, Harvard’s Catalyst Profiles, y el sistema VIVO financiado por NIH. Gracias a estos sistemas, los académicos se identifican de forma única a través de sus ID’s institucionales y están vinculados a los trabajos que se publican, las patentes de su autoría, la financiación recibida, y los cursos que imparten.
1. RESEARCH EXPERIENCE
The University of Washington, Seattle, WA May 2014-Present
Research Scientist I
Project 1
Philip J. Horner – Principal Investigator, Neurosurgery
• Directed Craig H. Neilsen Foundation collaborative grant project ‘Nerve Directed Tissue Regeneration’
• Developing a semi high-throughput optogenetic approach to manipulating nerve activity and growth
Project 2
Suzie H. Punn – Principal Investigator, Bioengineering and Philip J. Horner, Neurosurgery
• Collaborative grant project ‘Astrocyte Phage Display’
• Defining new astrocytic markers utilizing phage display libraries
Project 3
Robert C. Rostomily – Principal Investigator, Neurosurgery
• Breeding and maintenance of transgenic mouse colony for syngeneic transplant model of gliomas
• Investigation of the role of TWIST1 protein in tumorigenicity
• Drug sensitivity assays on mouse and human tumor cell lines
Project 4
Vincenzino Cirulli and Laura Crisa, Principal Investigators, Diabetes and Obesity Center of Excellence and Institute for Stem
Cell and Regenerative Medicine
• Mechanisms of islet cell function in co-culture with sympathetic cervical ganglia
Project 5
Zin Z. Zhaing, Neurosurgery
• Development and characterization of 3D anisotropic collagen hydrogels for spinal cord injury
The University of Akron, Akron, Ohio
Research Assistant January 2013-May 2013
Brian L. Davis - Principal Investigator and Chair, Biomedical Engineering
• Application of new motion analysis software for use in future clinical studies
• Preparation and writing of proposals/grant research
• Clinical research coordination for shear stress of the diabetic foot in prevention of ulcers
Research Assistant January 2011-January 2013
Nic D. Leipzig - Principal Investigator, Chemical and Biomolecular Engineering
• Incorporation of existing bioreactor into re-engineered polymer design
• Characterization of neuronal differentiation through immunohistochemistry and fluorescent microscopy
Starbucks, Student Manager August 2008-January 2011
PUBLICATIONS
1.
Electrical Stimulation to Enhance Neurite Outgrowth and Maturation of Neural Stem Progenitor Cells. Liza J. Kobelt,
Ashley E. Wilkinson, Aleesha M. McCormick, Rebecca Kuntz Willits, Nic D. Leipzig. Annals of Biomedical Engineering.
40(10): 2164-2176. 2014. Department of Chemical and Biomolecular Engineering, The University of Akron, Akron, OH.
2.
The effects of ECM ligand type and concentration on neural stem cell differentiation. Ashley E. Wilkinson, Liza J. Kobelt,
Nic D. Leipzig. Journal of Biomedical Materials Research Part A. 102(10): 3419-3428. 2014. Department of Chemical and
Biomolecular Engineering, The University of Akron, Akron, OH.
Manuscripts in preparation
3.
Biomimetic Injectable 3D Hydrogels with Aligned Topography for Neural Tissue Engineering. Liza J. Kobelt, Lindsay N.
Cates, Philip J. Horner, Christoph P. Hofstetter, Zin Z. Khaing.
Liza Severs
1920 Queen Anne Ave. N. #339 Seattle, WA 98109
330-904-4118
lkobelt@uw.edu
2. ABSTRACTS
1.
A Semi-High Throughput Optogenetic Approach for Modeling Nerve Directed Tissue Regeneration. Liza J. Kobelt, Suzie
H. Punn, Jane M. Sullivan, Steve I. Perlmutter, Philip J. Horner. To be presented at The International Symposium on Neural
Regeneration. Annual meeting on November 30th
- December 4th
, 2015. Asilomar Conference Grounds, Pacific Grove, CA.
Poster Presentation.
2.
Biomimetic Injectable 3D Hydrogels with Aligned Topography for Neural Tissue Engineering. Liza J. Kobelt, Lindsay N.
Cates, Philip J. Horner, Christoph P. Hofstetter, Zin Z. Khaing. To be presented at International Symposium on Neural
Regeneration. Annual Meeting on November 30th
-December 4th
, 2015. Asilomar Conference Grounds, Pacific Grove, CA.
Poster presentation.
3.
Biomimetic Injectable 3D Hydrogels with Aligned Topography for Neural Tissue Engineering. Liza J. Kobelt, Lindsay N.
Cates, Philip J. Horner, Christoph P. Hofstetter, Zin Z. Khaing. To be presented at Society for Neuroscience. Annual
Meeting on October 19-23, 2015. Chicago, IL. Poster presentation.
4.
Biomimetic Injectable 3D Hydrogels with Aligned Topography for Neural Tissue Engineering. Liza J. Kobelt, Lindsay N.
Cates, Philip J. Horner, Christoph P. Hofstetter, Zin Z. Khaing. To be presented at Biomedical Engineering Society. Annual
Meeting on October 7-10, 2015. Tampa, Fl. Poster presentation.
5.
Electrical Stimulation to Enhance Neurite Outgrowth and Differentiation in Neural Stem Progenitor Cells. Liza J. Kobelt,
Ashley E. Wilkinson, Aleesha M. McCormick, Rebecca Kuntz Willits, Nic D. Leipzig. Biomedical Engineering Society
National Meeting, Oral platform presentation. October 27, 2012. Atlanta, GA.
6.
Electrical Stimulation to Enhance Neurite Outgrowth In Neural Stem Cells. Liza J. Kobelt, Ashley E. Wilkinson, Aleesha
M. McCormick, Rebecca Kuntz Willits, Nic D. Leipzig. Ohio Academy of Science poster presentation April 14, 2012.
Ashland University, Ashland, OH.
7.
Differentiation and Tensile Elongation of Neural Stem Cells for Neural Tissue Engineering. Ashley E. Wilkinson, Liza J.
Kobelt, Nic D. Leipzig. Biomedical Engineering Society 2011 Annual Meeting. October 15, 2011. Hartford, CT. Poster
presentation.
EDUCATION
The University of Washington, Seattle, WA Spring 2015
• Relevant Graduate Coursework: Genetics, Genomics, and Evolution; Biophysics of Calcium Signaling
Bachelor of Science, Biology, The University of Akron, Akron, OH Dec. 14, 2012
• Relevant Undergraduate Coursework: Immunology, Neurobiology, Renal Physiology, Cardiovascular
Physiology, Cancer Biology, Tissue Engineering, Calculus, Physics
• The University of Akron Honors Program
• Ritchie Hall Program Board, Emerging Leaders
MENTORING
• Jeanette Schwenson, Summer 2015
• Regan Wortley, Summer 2014
• Lee Williams, Summer 2014
MEMBERSHIP/SCHOLARLY SOCIETIES
• Neurobiology and Behavior Community Outreach, The University of Washington
3. • Washington Biotechnology & Biomedical Association (WBBA)
• Society of Women Engineers (SWE)
• International Society for Pharmaceutical Engineering (ISPE), Vice President 2012 at The University of Akron
• Biomedical Engineering Society (BMES), Recipient of 2012 Travel award National Conference
VOLUNTEER WORK
• Department of Neurological Surgery, Volunteer March-May 2014
• Local outreach at Elementary School science fairs
• BEST Medicine Engineering Fair, National Inventors Hall of Fame School March 9,
2013
• Science Olympiad March
2012
CORE SKILLS AND QUALIFICATIONS
Completion of all animal and safety training required for The University of Washington
Cell isolation and culture
Live animal surgeries
Optogenetics
Assay Development
Fluorescent, Confocal, Live Imaging, Stereology, and 2-photon Microscopy
Immunocytochemistry/Immunohistochemistry techniques
Vibratome Sectioning
qPCR/PCR
Drug Assaying
AAV/MULV production
Adobe Illustrator and Photoshop
CITI Certified
Auto Cad Design Software
Adobe Illustrator
Microsoft Office Suite