Christian Geiß has over 10 years of experience in the pharmaceutical and research fields. He currently works as a sales representative for Novo Nordisk Pharma GmbH, where he is responsible for revenue generation and new product launches. Previously, he worked as a sales representative for Berlin-Chemie/Menarini AG and as a research associate obtaining his PhD in biophysics. He has strong skills in IT, computing, and programming.
Course:
"Medicines for older adults: Getting prepared for the scientific and regulatory evolution"
Place: 07 to 08 November 2017, Hotel Das Weitzer, Graz,
Austria
Chairs: Sven Stegemann, Graz University of Technology, Graz, Austria; Capsugel Carsten Timpe, F. Hoffmann-La Roche Ltd., Basle, Switzerland
It’s an expensive und exhausting run against time: It takes approximately 2,3 billion Dollars and 12 years to bring a drug to the market. This leaves only 8 years until the expiration of the patent to bring back sufficient return on investments. So far, this has worked out well for the industry but the run is getting steeper every year: on the one hand, it becomes increasingly complex and expensive to develop new drugs, on the other hand prizes are under scrutiny. Hence, the industry is sitting on a time bomb, as the day will come when the returns will not cover the investments anymore and the innovation pipeline will dry out because bringing new drugs to the market does no longer offer any financial incentives.
What can be done about this scenario? Eventually (and hopefully), these projections prove wrong as there is still a lot to be gained by efficiency improvement through digitalizing all along the value chain – after all healthcare still is one of the least digitalized industries. Will this be enough – or do we have to reinvent healthcare innovation in a radical new way?
This DayOne Experts Event showcased some game changing ideas and discussed their feasibility and impact with an expert panel and the audience. These slides are just the intro to this Event.
Master in Cell Biology with thorough knowledge about Diabetes Care.
Excellent communication skills and poses a creative mind finding solutions in the most constructive way.
Course:
"Medicines for older adults: Getting prepared for the scientific and regulatory evolution"
Place: 07 to 08 November 2017, Hotel Das Weitzer, Graz,
Austria
Chairs: Sven Stegemann, Graz University of Technology, Graz, Austria; Capsugel Carsten Timpe, F. Hoffmann-La Roche Ltd., Basle, Switzerland
It’s an expensive und exhausting run against time: It takes approximately 2,3 billion Dollars and 12 years to bring a drug to the market. This leaves only 8 years until the expiration of the patent to bring back sufficient return on investments. So far, this has worked out well for the industry but the run is getting steeper every year: on the one hand, it becomes increasingly complex and expensive to develop new drugs, on the other hand prizes are under scrutiny. Hence, the industry is sitting on a time bomb, as the day will come when the returns will not cover the investments anymore and the innovation pipeline will dry out because bringing new drugs to the market does no longer offer any financial incentives.
What can be done about this scenario? Eventually (and hopefully), these projections prove wrong as there is still a lot to be gained by efficiency improvement through digitalizing all along the value chain – after all healthcare still is one of the least digitalized industries. Will this be enough – or do we have to reinvent healthcare innovation in a radical new way?
This DayOne Experts Event showcased some game changing ideas and discussed their feasibility and impact with an expert panel and the audience. These slides are just the intro to this Event.
Master in Cell Biology with thorough knowledge about Diabetes Care.
Excellent communication skills and poses a creative mind finding solutions in the most constructive way.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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CV 09.2019 Christian Geiß
1. PROFESSIONAL EXPERIENCE
Pharmaceutical Field Force
July 2018 – current
> Sales Rep. for Novo Nordisk Pharma GmbH for diabetes and obesity for
diabetelogists, gastroenterologists und diabetology-practising GPs in the
clinical field and surgery in the Offenbach-Fulda district
> Full responsibility for the revenue of insulines: Fiasp®(max. market share 7.5%
M-Bolus since launch 04/17; largest market share increase of 1.2% for tertial
2/2019 in the region; 2. place team ranking (12 employees))/Tresiba®(0.5%
market share > BRD-average for MI-Basal since launch 12/2018; 3. Place team
ranking (12 employees))
> Launching novel medical drugs (Tresiba® 12/18 & Ozempic® 02/19 -> KOL
acquisition to condcut Ozempic® launch training events for GPIs)
> Planing, organisation and conducting physicians training courses (sponsorings,
Novo Nordisk events)
> Market observation und -analyses (FGM/HotBricks) for developing in-field
sales strategies
> Participation in national/international congresses to foster B2B and facilitate
personal training (DDG, EASD – Award: booth worker of the day)
> Scientific dialogue with physicians supported by marketing detailer, primary
publications and prescribing information
> Cross-functional team work with field hospital account/market access
manager and regional medical advisor
> Member of the cross-functional Tresiba® product group with brand- &
marketing manager diabetes
> IT key user for the field force team, managing SELAS (CRM-tool) and general
OS issues
Aprile 2017 – June 2018
> Sales Rep. for Berlin-Chemie/Menarini AG for diabetes type II,
hypercholesterinaemia and symptomatic hyperuricaemia for GPs and
pharmacies in the Hanau-Fulda district
> Organisation of ICD-10 documentation courses & patient support programs
(TheraKey)
> Cross-functional collaborations with product manager & medical advisor
Research Associate
March 2011 – June 2016
> PhD Thesis at the Institute for Biphysics under leadership of Prof. Achilleas S.
Frangakis at the Goethe University of Frankfurt (Germany) entitled „3D struc-
tural investigation of centromeric chromatin and active ribosomal genes by
cryo-electron tomography”.
> Basic key tasks: project planning, method development, literature research,
teaching, publishing, supervision of courses and research assistants, fostering
relationships with international partners, networking
EDUCATION
May 2010 – October 2010
Master Thesis at the MPI for Biophysics under leadership of Prof. Hartmut
Michel at the Goethe University of Frankfurt (Germany) entitled „Establishment
and application of a 2D-nanoLC-based mass spectrometry-coupled system for
the quantitative analysis of COPI-vesicles & synaptic plasticity of hippocampal
neurons“.
May 2008 – July 2008
Bachelor Thesis at the Institute for Biochemistry under leadership of Prof.
Alfred Pingoud at the Justus Liebig University of Gießen (Germany) entitled
Christian
Geiß
> Biochemist (PhD)
Date and Place of Birth:
4.9.1984 / Frankfurt am Main
Citizenship:
German
Marital Status:
married
Adress:
Middle Germany, around
Frankfurt/Main
www.xing.com/profile/Christian_Geiss
www.linkedin.com/in/DrChristianGeiss
www.slideshare.net/DrChristianGei
2. Seite 2
„Production, purification and characterization of covalently linked complexes of
restriction endonucleases and triple-helix forming oligonucleotides“.
October 2005 – January 2011
Biology studies at the Justus Liebig University of Gießen (Germany)
Subjects: Biochemistry, Genetics, Microbiology, Analytical Chemistry
September 1991 – June 2004
Abitur and education at the Kopernikusschule Freigericht (Germany)
VOLUNTARY AND COMMUNITY SERVICE
September 2007 – November 2007
Voluntary service at the Iguana Breeding and Research Station (IRBS) of the
Senckenberg society for biodiversity in Utila (Honduras)
September 2004 – August 2005
Community service at the ‚Martinsschule‘ in Gelnhausen (Germany)
DEGRESS AND CERTIFICATIONS
> University-entrance diploma (Abitur)
> Bachelor/Master of Science (Biology)
> Doctoral degree in Natural Sciences (Dr. phil. nat.)
ADDITIONAL SKILLS
> Advanced knowledge in IT and computing (MS Office, Adobe image
processing, hard- und software problem solving, Linux, Windows)
> Basic programming skills (Matlab, Python, Perl)
> Deutsch (native)
> Englisch (fluent)
HOBBIES AND LEISURE TIME ACITIVITIES
> Reading of scientific journals (GBM e.V. membership since 2008)
> Honorary member of KUZ Hanau e.V. since 2015
> Singer in a band; composing own songs and organizing shows
> Travel&Cook: becoming acquainted with new cultures and local cuisine
PUBLICATIONS
Geiss, C.P., Keramisanou, D., Sekulic, N., Scheffer, M.P., Black, B.E., Frangakis,
A.S. (2014) CENP-A arrays are more condensed than canonical arrays at low
ionic strength. Biophysical Journal, 106, 875-882.
Neyer, S., Kunz, M., Geiss, C.P., Hantsche, M., Hodirnau, V.V., Seybert, A.,
Engel, C., Scheffer, M.P., Cramer, P., Frangakis, A.S. (2016) Structure of RNA
polymerase I transcribing rDNA genes. Nature, 540, 607-610.
SELECTION OF CONFERENCE CONTRIBUTIONS
7th International Congress on Electron Tomography
17.11-20.11.2014 (Cancun, Mexico)
Contribution: Talk with the title “Moleculare underpinnings of the
centromere”
3. Seite 3
SBBE 2012: Structural Biology in the BioEconomy
01.12-04.12.2012 (Capetown, Western Cape, South Africa)
Contribution: Poster presentation with the title “Cryo-electron tomography of
the spatial organization of the RNA polymerase and ribosomes in bacteria”