This document provides an overview of cost-effectiveness analysis (CEA) and how it can be used to compare different interventions that aim to reduce the same outcome, such as diarrhea. CEA measures the cost of an intervention relative to its impact on a single predefined outcome. The document outlines CEA of different interventions to reduce diarrhea incidence and their associated impacts and costs. It then discusses how to conduct a comparative CEA of education programs, including standardizing cost and impact estimates to common units to facilitate comparison.