Colecalciferol - Drug Information - Taj Pharma, Colecalciferol dose Taj pharmaceuticals Colecalciferol interactions, Taj Pharmaceutical Colecalciferol contraindications, Colecalciferol price, Colecalciferol Taj Pharma Colecalciferol 20 000 IU Capsules SMPC- Taj Pharma . Stay connected to all updated on Colecalciferol Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Colecalciferol d3 drops smpc- taj pharmaceuticalsTaj Pharma
Colecalciferol-D3 - Drug Information - Taj Pharma, Colecalciferol-D3 dose Taj pharmaceuticals Colecalciferol-D3 interactions, Taj Pharmaceutical Colecalciferol-D3 contraindications, Colecalciferol-D3 price, Colecalciferol-D3 Taj Pharma Colecalciferol-D3 Drops SMPC- Taj Pharma . Stay connected to all updated on Colecalciferol-D3 Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Carboplatin Injection BP 50mg/5ml, 150mg/15ml, 450mg/45ml, 600mg/60ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Carboplatin Dosage & Rx Info | Carboplatin Uses, Side Effects Carboplatin: Indications, Side Effects, Warnings, Carboplatin -Drug Information –Taj Pharma, Carboplatin dose Taj pharmaceuticals Carboplatin interactions, Taj Pharmaceutical Carboplatin contraindications, Carboplatin price, Carboplatin Taj Pharma Carboplatin SmPC-Taj Pharma Stay connected to all updated on Carboplatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Bicalutamide 50 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Bicalutamide - Drug Information - Taj Pharma, Bicalutamide dose Taj pharmaceuticals Bicalutamide interactions, Taj Pharmaceutical Bicalutamide contraindications, Bicalutamide price, Bicalutamide Taj Pharma Cancer, oncologyBicalutamide 50 mg film-coated Tablets SMPC- Taj Pharma . Stay connected to all updated on Bicalutamide Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Pregabalin SR Capsules Sustained Release 100mg/150mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Pregabalin Dosage & Rx Info | Pregabalin Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Pregabalin-Drug Information –Taj Pharma, Pregabalin dose Taj pharmaceuticals Pregabalin interactions, Taj Pharmaceutical Pregabalin contraindications, Pregabalin price, Pregabalin Taj Pharma Pregabalin SmPC-Taj Pharma Stay connected to all updated on Pregabalin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Amlodipine 10mg tablets smpc taj pharmaceuticalsTaj Pharma
Amlodipine 5mg, 10mg Tablets Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Amlodipine Dosage & Rx Info | Amlodipine Uses, Side Effects - Amlodipine : Indications, Side Effects, Warnings, Amlodipine - Drug Information - Taj Pharma, Amlodipine dose Taj pharmaceuticals Amlodipine interactions, Taj Pharmaceutical Amlodipine contraindications, Amlodipine price, Amlodipine Taj Pharma Amlodipine 5mg, 10mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Amlodipine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Carboplatin 10 mgml intravenous infusion smpc taj pharmaceuticalsTaj Pharma
CARBOPLATIN - Drug Information - Taj Pharma, CARBOPLATIN dose Taj pharmaceuticals CARBOPLATINinteractions, Taj Pharmaceutical CARBOPLATIN contraindications, CARBOPLATIN price, CARBOPLATIN Taj Pharma Cancer, oncologyCarboplatin 10 mg/ml Intravenous Infusion SMPC- Taj Pharma . Stay connected to all updated on CARBOPLATIN Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Colecalciferol d3 drops smpc- taj pharmaceuticalsTaj Pharma
Colecalciferol-D3 - Drug Information - Taj Pharma, Colecalciferol-D3 dose Taj pharmaceuticals Colecalciferol-D3 interactions, Taj Pharmaceutical Colecalciferol-D3 contraindications, Colecalciferol-D3 price, Colecalciferol-D3 Taj Pharma Colecalciferol-D3 Drops SMPC- Taj Pharma . Stay connected to all updated on Colecalciferol-D3 Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Carboplatin Injection BP 50mg/5ml, 150mg/15ml, 450mg/45ml, 600mg/60ml Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Carboplatin Dosage & Rx Info | Carboplatin Uses, Side Effects Carboplatin: Indications, Side Effects, Warnings, Carboplatin -Drug Information –Taj Pharma, Carboplatin dose Taj pharmaceuticals Carboplatin interactions, Taj Pharmaceutical Carboplatin contraindications, Carboplatin price, Carboplatin Taj Pharma Carboplatin SmPC-Taj Pharma Stay connected to all updated on Carboplatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Bicalutamide 50 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Bicalutamide - Drug Information - Taj Pharma, Bicalutamide dose Taj pharmaceuticals Bicalutamide interactions, Taj Pharmaceutical Bicalutamide contraindications, Bicalutamide price, Bicalutamide Taj Pharma Cancer, oncologyBicalutamide 50 mg film-coated Tablets SMPC- Taj Pharma . Stay connected to all updated on Bicalutamide Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Pregabalin SR Capsules Sustained Release 100mg/150mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Pregabalin Dosage & Rx Info | Pregabalin Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Pregabalin-Drug Information –Taj Pharma, Pregabalin dose Taj pharmaceuticals Pregabalin interactions, Taj Pharmaceutical Pregabalin contraindications, Pregabalin price, Pregabalin Taj Pharma Pregabalin SmPC-Taj Pharma Stay connected to all updated on Pregabalin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Amlodipine 10mg tablets smpc taj pharmaceuticalsTaj Pharma
Amlodipine 5mg, 10mg Tablets Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Amlodipine Dosage & Rx Info | Amlodipine Uses, Side Effects - Amlodipine : Indications, Side Effects, Warnings, Amlodipine - Drug Information - Taj Pharma, Amlodipine dose Taj pharmaceuticals Amlodipine interactions, Taj Pharmaceutical Amlodipine contraindications, Amlodipine price, Amlodipine Taj Pharma Amlodipine 5mg, 10mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Amlodipine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Carboplatin 10 mgml intravenous infusion smpc taj pharmaceuticalsTaj Pharma
CARBOPLATIN - Drug Information - Taj Pharma, CARBOPLATIN dose Taj pharmaceuticals CARBOPLATINinteractions, Taj Pharmaceutical CARBOPLATIN contraindications, CARBOPLATIN price, CARBOPLATIN Taj Pharma Cancer, oncologyCarboplatin 10 mg/ml Intravenous Infusion SMPC- Taj Pharma . Stay connected to all updated on CARBOPLATIN Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Cyanocobalamin 50 micrograms tablets pil, taj pharmaceuticals.Taj Pharma
This document is a patient information leaflet for Cyanocobalamin 50 micrograms Tablets produced by Taj Pharmaceuticals. It provides information on what cyanocobalamin (vitamin B12) is used for, how the tablets should be taken, possible side effects, and storage instructions. Cyanocobalamin tablets are used to treat vitamin B12 deficiency when injections cannot be used, for conditions such as pernicious anemia. The recommended adult dose is 1-3 tablets daily taken orally with water between meals. Allergic reactions are a rare potential side effect.
This document provides information on lacosamide tablets produced by Taj Pharma, including:
- It describes the composition, pharmaceutical form, clinical uses, dosages, and administration details for lacosamide tablets in 50mg, 100mg, 150mg, and 200mg strengths.
- The tablets are indicated as monotherapy or adjunctive therapy for partial-onset seizures. Common side effects include nausea and vomiting. Special populations may require adjusted dosages.
- Detailed posology and dosage adjustment recommendations are provided for various patient populations including children, elderly patients, and those with renal or hepatic impairment.
Olmesartan medoxomil and Amlodipine Tablets Taj Pharma SmPCTajPharmaQC
The document discusses Olmesartan medoxomil and Amlodipine besilate tablets, which are fixed-dose combination antihypertensive medications produced by Taj Pharmaceuticals. It provides information on the composition of the tablets, therapeutic indications for treating hypertension, dosing and administration guidance stratified by factors like renal or hepatic impairment, contraindications, and warnings regarding dual renin-angiotensin system blockade or use in pregnancy. The document also includes sections on clinical pharmacology, interactions, adverse effects, and overdose management.
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
Paracetamol and Ibuprofen - Drug Information - Taj Pharma, Paracetamol and Ibuprofen dose Taj pharmaceuticals Paracetamol and Ibuprofen interactions, Taj Pharmaceutical Paracetamol and Ibuprofen contraindications, Paracetamol and Ibuprofen price, Paracetamol and Ibuprofen Taj Pharma Paracetamol and Ibuprofen 500 mg/150 mg film coated tablets SMPC- Taj Pharma . Stay connected to all updated on Paracetamol and Ibuprofen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Clarithromycin for Injection Taj Pharma SmPCTajPharmaQC
Clarithromycin for Infusion 500mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Clarithromycin Dosage & Rx Info | Clarithromycin Uses, Side Effects Clarithromycin: Indications, Side Effects, Warnings, Clarithromycin -Drug Information –Taj Pharma, Clarithromycin dose Taj pharmaceuticals Clarithromycin interactions, Taj Pharmaceutical Clarithromycin contraindications, Clarithromycin price, Clarithromycin Taj Pharma Clarithromycin SmPC-Taj Pharma Stay connected to all updated on Clarithromycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Multivitamin capsules smpc taj pharmaceuticalsTaj Pharma
MULTIVITAMIN CAPSULES Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, MULTIVITAMIN CAPSULES Dosage & Rx Info | MULTIVITAMIN CAPSULES Uses, Side Effects -: Indications, Side Effects, Warnings, MULTIVITAMIN CAPSULES - Drug Information - Taj Pharma, MULTIVITAMIN CAPSULES dose Taj pharmaceuticals MULTIVITAMIN CAPSULES interactions, Taj Pharmaceutical MULTIVITAMIN CAPSULES contraindications, MULTIVITAMIN CAPSULES price, MULTIVITAMIN CAPSULES Taj Pharma MULTIVITAMIN CAPSULES SMPC- Taj Pharma . Stay connected to all updated on MULTIVITAMIN CAPSULES Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Oxaliplatin for Injection Taj Pharma SmPCTajPharmaQC
Oxaliplatin for Injection 50mg, 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Oxaliplatin Dosage & Rx Info | Oxaliplatin Uses, Side Effects Oxaliplatin: Indications, Side Effects, Warnings, Oxaliplatin -Drug Information –Taj Pharma, Oxaliplatin dose Taj pharmaceuticals Oxaliplatin interactions, Taj Pharmaceutical Oxaliplatin contraindications, Oxaliplatin price, Oxaliplatin Taj Pharma Oxaliplatin SmPC-Taj Pharma Stay connected to all updated on Oxaliplatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Allopurinol 300mg tablets smpc taj pharmaceuticalsTaj Pharma
This document provides information on allopurinol 300mg tablets produced by Taj Pharmaceuticals, including:
- Indications for use in reducing urate/uric acid formation in conditions like gout and kidney stones.
- Dosage and administration details for adults, children, elderly, and those with renal/hepatic impairment.
- Contraindications and warnings about potential hypersensitivity reactions and interactions with other medications that may increase effects.
- Advice on monitoring therapy and adjusting the dose based on serum urate levels.
Carbamazepine 200 mg tablets smpc taj pharmaceuticalsTaj Pharma
Carbamazepine Uses, Side Effects -: Indications, Side Effects, Warnings, Carbamazepine - Drug Information - Taj Pharma, Carbamazepine dose Taj pharmaceuticals Carbamazepine interactions, Taj Pharmaceutical Carbamazepine contraindications, Carbamazepine price, Carbamazepine Taj Pharma Carbamazepine 200 mg tablets SMPC- Taj Pharma . Stay connected to all updated on Carbamazepine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Amodiaquine hydrochloride tablets smpc taj pharmaceuticalsTaj Pharma
Amodiaquine Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Amodiaquine Dosage & Rx Info | Amodiaquine Uses, Side Effects -: Indications, Side Effects, Warnings, Amodiaquine - Drug Information - Taj Pharma, Amodiaquine dose Taj pharmaceuticals Amodiaquine interactions, Taj Pharmaceutical Amodiaquine contraindications, Amodiaquine price, Amodiaquine Taj Pharma Amodiaquine hydrochloride tablets SMPC- Taj Pharma . Stay connected to all updated on Amodiaquine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Diclofenac potassium 50 mg tablets smpc taj pharmaceuticalsTaj Pharma
Diclofenac Potassium Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Diclofenac Potassium Dosage & Rx Info | Diclofenac Potassium Uses, Side Effects -: Indications, Side Effects, Warnings, Diclofenac Potassium - Drug Information - Taj Pharma, Diclofenac Potassium dose Taj pharmaceuticals Diclofenac Potassium interactions, Taj Pharmaceutical Diclofenac Potassium contraindications, Diclofenac Potassium price, Diclofenac Potassium Taj Pharma Diclofenac Potassium 50 mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Diclofenac Potassium Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Zoledronic acid Solution for Infusion Taj Pharma SmPCTajPharmaQC
1. The document provides information on Zoledronic acid 4 mg/100 ml Solution for Infusion, including its uses, posology, method of administration, contraindications and warnings.
2. It is used for prevention of skeletal related events in patients with advanced malignancies involving bone and for treatment of tumour-induced hypercalcaemia.
3. Dosing depends on renal function - normal renal function receives 4 mg every 3-4 weeks, while mild-moderate impairment receives reduced doses. It should be administered by intravenous infusion over at least 15 minutes.
Chloroquine phosphate 250 mg tablets smpc taj pharmaceuticalsTaj Pharma
Chloroquine phosphate 250 mg Tablets SMPC: Indications, Side Effects, Warnings, Chloroquinen - Drug Information - Taj Pharma, Chloroquinen dose Taj pharmaceuticals Chloroquinen interactions, Taj Pharmaceutical Chloroquinen contraindications, Chloroquinen price, Chloroquinen , Taj Pharma Chloroquine phosphate 250 mg Tablets SMPC - Taj Pharma . Stay connected to all updated on Chloroquinen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Abiraterone acetate 500 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Abiraterone Acetate 500 mg film-coated tablets are indicated for the treatment of metastatic castration-resistant prostate cancer in combination with prednisone or prednisolone. Common side effects include hypertension, hypokalemia, and fluid retention due to increased mineralocorticoid levels. Liver function tests should be monitored regularly during treatment due to potential for hepatotoxicity. Patients with moderate or severe hepatic impairment, uncontrolled hypertension, clinically significant heart disease, or severe renal impairment should not take Abiraterone Acetate.
Bicalutamide Tablets USP Taj Pharma SmPCTajPharmaQC
Bicalutamide Tablets USP 50mg/150mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Bicalutamide Dosage & Rx Info | Bicalutamide Uses, Side Effects Bicalutamide : Indications, Side Effects, Warnings, Bicalutamide -Drug Information –Taj Pharma, Bicalutamide dose Taj pharmaceuticals Bicalutamide interactions, Taj Pharmaceutical Bicalutamide contraindications, Bicalutamide price, Bicalutamide Taj Pharma Bicalutamide SmPC-Taj Pharma Stay connected to all updated on Bicalutamide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Paliperidone ER Tablets Taj Pharma SmPCTajPharmaQC
Paliperidone 3mg/6mg/9mg/12mg Extended-release Tablets Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Paliperidone Dosage & Rx Info | Paliperidone Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Paliperidone-Drug Information –Taj Pharma, Paliperidone dose Taj pharmaceuticals Paliperidone interactions, Taj Pharmaceutical Paliperidone contraindications, Paliperidone price, Paliperidone Taj Pharma Paliperidone SmPC-Taj Pharma Stay connected to all updated on Paliperidone Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Captopril 25 mg tablets smpc taj pharmaceuticalsTaj Pharma
1. Captopril 25 mg tablets contain the active ingredient captopril, which is used to treat hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathy.
2. The recommended starting dose for hypertension is 25-50 mg daily and the maximum dose is 150 mg daily. For congestive heart failure and myocardial infarction, dosing should be individualized and started at a low dose under close medical supervision.
3. Special warnings include risks of hypotension, especially in volume-depleted patients or those with renal artery stenosis. Angioedema is also a risk and can be life-threatening if the airway is involved. Renal function should be monitored in patients with impaired
The document provides information about Calutide tablets, which contain the generic drug bicalutamide used to treat prostate cancer. It indicates that Calutide tablets are used in combination with LHRH analogue therapy for advanced prostate cancer or as adjuvant therapy with prostatectomy or radiotherapy for locally advanced, high-risk prostate cancer. The document discusses dosage, contraindications, side effects and warnings, storage, and overdosage related to treatment with Calutide tablets.
Crizotinib Capsules 200mg, 250mg Taj Pharma PILTajPharmaQC
Crizotinib 200mg/250mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Crizotinib Dosage & Rx Info | Crizotinib Uses, Side Effects Crizotinib: Indications, Side Effects, Warnings, Crizotinib -Drug Information –Taj Pharma, Crizotinib dose Taj pharmaceuticals Crizotinib interactions, Taj Pharmaceutical Crizotinib contraindications, Crizotinib price, Crizotinib Taj Pharma Crizotinib SmPC-Taj Pharma Stay connected to all updated on Crizotinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Bisacodyl 5 mg gastro resistant tablets smpc- taj pharmaceuticalsTaj Pharma
Bisacodyl Uses, Side Effects -: Indications, Side Effects, Warnings, Bisacodyl - Drug Information - Taj Pharma, Bisacodyl dose Taj pharmaceuticals Bisacodyl interactions, Taj Pharmaceutical Bisacodyl contraindications, Bisacodyl price, Bisacodyl Taj Pharma Bisacodyl 5 mg Gastro-resistant Tablets SMPC- Taj Pharma . Stay connected to all updated on Bisacodyl Taj Pharmaceuticals Taj pharmaceuticals Hyderabad
Cyanocobalamin 50 micrograms tablets pil, taj pharmaceuticals.Taj Pharma
This document is a patient information leaflet for Cyanocobalamin 50 micrograms Tablets produced by Taj Pharmaceuticals. It provides information on what cyanocobalamin (vitamin B12) is used for, how the tablets should be taken, possible side effects, and storage instructions. Cyanocobalamin tablets are used to treat vitamin B12 deficiency when injections cannot be used, for conditions such as pernicious anemia. The recommended adult dose is 1-3 tablets daily taken orally with water between meals. Allergic reactions are a rare potential side effect.
This document provides information on lacosamide tablets produced by Taj Pharma, including:
- It describes the composition, pharmaceutical form, clinical uses, dosages, and administration details for lacosamide tablets in 50mg, 100mg, 150mg, and 200mg strengths.
- The tablets are indicated as monotherapy or adjunctive therapy for partial-onset seizures. Common side effects include nausea and vomiting. Special populations may require adjusted dosages.
- Detailed posology and dosage adjustment recommendations are provided for various patient populations including children, elderly patients, and those with renal or hepatic impairment.
Olmesartan medoxomil and Amlodipine Tablets Taj Pharma SmPCTajPharmaQC
The document discusses Olmesartan medoxomil and Amlodipine besilate tablets, which are fixed-dose combination antihypertensive medications produced by Taj Pharmaceuticals. It provides information on the composition of the tablets, therapeutic indications for treating hypertension, dosing and administration guidance stratified by factors like renal or hepatic impairment, contraindications, and warnings regarding dual renin-angiotensin system blockade or use in pregnancy. The document also includes sections on clinical pharmacology, interactions, adverse effects, and overdose management.
Paracetamol and ibuprofen 500 mg and 150 mg film coated tablets smpc taj pha...Taj Pharma
Paracetamol and Ibuprofen - Drug Information - Taj Pharma, Paracetamol and Ibuprofen dose Taj pharmaceuticals Paracetamol and Ibuprofen interactions, Taj Pharmaceutical Paracetamol and Ibuprofen contraindications, Paracetamol and Ibuprofen price, Paracetamol and Ibuprofen Taj Pharma Paracetamol and Ibuprofen 500 mg/150 mg film coated tablets SMPC- Taj Pharma . Stay connected to all updated on Paracetamol and Ibuprofen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Clarithromycin for Injection Taj Pharma SmPCTajPharmaQC
Clarithromycin for Infusion 500mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Clarithromycin Dosage & Rx Info | Clarithromycin Uses, Side Effects Clarithromycin: Indications, Side Effects, Warnings, Clarithromycin -Drug Information –Taj Pharma, Clarithromycin dose Taj pharmaceuticals Clarithromycin interactions, Taj Pharmaceutical Clarithromycin contraindications, Clarithromycin price, Clarithromycin Taj Pharma Clarithromycin SmPC-Taj Pharma Stay connected to all updated on Clarithromycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Multivitamin capsules smpc taj pharmaceuticalsTaj Pharma
MULTIVITAMIN CAPSULES Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, MULTIVITAMIN CAPSULES Dosage & Rx Info | MULTIVITAMIN CAPSULES Uses, Side Effects -: Indications, Side Effects, Warnings, MULTIVITAMIN CAPSULES - Drug Information - Taj Pharma, MULTIVITAMIN CAPSULES dose Taj pharmaceuticals MULTIVITAMIN CAPSULES interactions, Taj Pharmaceutical MULTIVITAMIN CAPSULES contraindications, MULTIVITAMIN CAPSULES price, MULTIVITAMIN CAPSULES Taj Pharma MULTIVITAMIN CAPSULES SMPC- Taj Pharma . Stay connected to all updated on MULTIVITAMIN CAPSULES Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Oxaliplatin for Injection Taj Pharma SmPCTajPharmaQC
Oxaliplatin for Injection 50mg, 100mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Oxaliplatin Dosage & Rx Info | Oxaliplatin Uses, Side Effects Oxaliplatin: Indications, Side Effects, Warnings, Oxaliplatin -Drug Information –Taj Pharma, Oxaliplatin dose Taj pharmaceuticals Oxaliplatin interactions, Taj Pharmaceutical Oxaliplatin contraindications, Oxaliplatin price, Oxaliplatin Taj Pharma Oxaliplatin SmPC-Taj Pharma Stay connected to all updated on Oxaliplatin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Allopurinol 300mg tablets smpc taj pharmaceuticalsTaj Pharma
This document provides information on allopurinol 300mg tablets produced by Taj Pharmaceuticals, including:
- Indications for use in reducing urate/uric acid formation in conditions like gout and kidney stones.
- Dosage and administration details for adults, children, elderly, and those with renal/hepatic impairment.
- Contraindications and warnings about potential hypersensitivity reactions and interactions with other medications that may increase effects.
- Advice on monitoring therapy and adjusting the dose based on serum urate levels.
Carbamazepine 200 mg tablets smpc taj pharmaceuticalsTaj Pharma
Carbamazepine Uses, Side Effects -: Indications, Side Effects, Warnings, Carbamazepine - Drug Information - Taj Pharma, Carbamazepine dose Taj pharmaceuticals Carbamazepine interactions, Taj Pharmaceutical Carbamazepine contraindications, Carbamazepine price, Carbamazepine Taj Pharma Carbamazepine 200 mg tablets SMPC- Taj Pharma . Stay connected to all updated on Carbamazepine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Amodiaquine hydrochloride tablets smpc taj pharmaceuticalsTaj Pharma
Amodiaquine Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Amodiaquine Dosage & Rx Info | Amodiaquine Uses, Side Effects -: Indications, Side Effects, Warnings, Amodiaquine - Drug Information - Taj Pharma, Amodiaquine dose Taj pharmaceuticals Amodiaquine interactions, Taj Pharmaceutical Amodiaquine contraindications, Amodiaquine price, Amodiaquine Taj Pharma Amodiaquine hydrochloride tablets SMPC- Taj Pharma . Stay connected to all updated on Amodiaquine Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Diclofenac potassium 50 mg tablets smpc taj pharmaceuticalsTaj Pharma
Diclofenac Potassium Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Diclofenac Potassium Dosage & Rx Info | Diclofenac Potassium Uses, Side Effects -: Indications, Side Effects, Warnings, Diclofenac Potassium - Drug Information - Taj Pharma, Diclofenac Potassium dose Taj pharmaceuticals Diclofenac Potassium interactions, Taj Pharmaceutical Diclofenac Potassium contraindications, Diclofenac Potassium price, Diclofenac Potassium Taj Pharma Diclofenac Potassium 50 mg Tablets SMPC- Taj Pharma . Stay connected to all updated on Diclofenac Potassium Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Zoledronic acid Solution for Infusion Taj Pharma SmPCTajPharmaQC
1. The document provides information on Zoledronic acid 4 mg/100 ml Solution for Infusion, including its uses, posology, method of administration, contraindications and warnings.
2. It is used for prevention of skeletal related events in patients with advanced malignancies involving bone and for treatment of tumour-induced hypercalcaemia.
3. Dosing depends on renal function - normal renal function receives 4 mg every 3-4 weeks, while mild-moderate impairment receives reduced doses. It should be administered by intravenous infusion over at least 15 minutes.
Chloroquine phosphate 250 mg tablets smpc taj pharmaceuticalsTaj Pharma
Chloroquine phosphate 250 mg Tablets SMPC: Indications, Side Effects, Warnings, Chloroquinen - Drug Information - Taj Pharma, Chloroquinen dose Taj pharmaceuticals Chloroquinen interactions, Taj Pharmaceutical Chloroquinen contraindications, Chloroquinen price, Chloroquinen , Taj Pharma Chloroquine phosphate 250 mg Tablets SMPC - Taj Pharma . Stay connected to all updated on Chloroquinen Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Abiraterone acetate 500 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
Abiraterone Acetate 500 mg film-coated tablets are indicated for the treatment of metastatic castration-resistant prostate cancer in combination with prednisone or prednisolone. Common side effects include hypertension, hypokalemia, and fluid retention due to increased mineralocorticoid levels. Liver function tests should be monitored regularly during treatment due to potential for hepatotoxicity. Patients with moderate or severe hepatic impairment, uncontrolled hypertension, clinically significant heart disease, or severe renal impairment should not take Abiraterone Acetate.
Bicalutamide Tablets USP Taj Pharma SmPCTajPharmaQC
Bicalutamide Tablets USP 50mg/150mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Bicalutamide Dosage & Rx Info | Bicalutamide Uses, Side Effects Bicalutamide : Indications, Side Effects, Warnings, Bicalutamide -Drug Information –Taj Pharma, Bicalutamide dose Taj pharmaceuticals Bicalutamide interactions, Taj Pharmaceutical Bicalutamide contraindications, Bicalutamide price, Bicalutamide Taj Pharma Bicalutamide SmPC-Taj Pharma Stay connected to all updated on Bicalutamide Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Paliperidone ER Tablets Taj Pharma SmPCTajPharmaQC
Paliperidone 3mg/6mg/9mg/12mg Extended-release Tablets Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Paliperidone Dosage & Rx Info | Paliperidone Uses, Side Effects Vecuronium bromide: Indications, Side Effects, Warnings, Paliperidone-Drug Information –Taj Pharma, Paliperidone dose Taj pharmaceuticals Paliperidone interactions, Taj Pharmaceutical Paliperidone contraindications, Paliperidone price, Paliperidone Taj Pharma Paliperidone SmPC-Taj Pharma Stay connected to all updated on Paliperidone Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
Captopril 25 mg tablets smpc taj pharmaceuticalsTaj Pharma
1. Captopril 25 mg tablets contain the active ingredient captopril, which is used to treat hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathy.
2. The recommended starting dose for hypertension is 25-50 mg daily and the maximum dose is 150 mg daily. For congestive heart failure and myocardial infarction, dosing should be individualized and started at a low dose under close medical supervision.
3. Special warnings include risks of hypotension, especially in volume-depleted patients or those with renal artery stenosis. Angioedema is also a risk and can be life-threatening if the airway is involved. Renal function should be monitored in patients with impaired
The document provides information about Calutide tablets, which contain the generic drug bicalutamide used to treat prostate cancer. It indicates that Calutide tablets are used in combination with LHRH analogue therapy for advanced prostate cancer or as adjuvant therapy with prostatectomy or radiotherapy for locally advanced, high-risk prostate cancer. The document discusses dosage, contraindications, side effects and warnings, storage, and overdosage related to treatment with Calutide tablets.
Crizotinib Capsules 200mg, 250mg Taj Pharma PILTajPharmaQC
Crizotinib 200mg/250mg Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Crizotinib Dosage & Rx Info | Crizotinib Uses, Side Effects Crizotinib: Indications, Side Effects, Warnings, Crizotinib -Drug Information –Taj Pharma, Crizotinib dose Taj pharmaceuticals Crizotinib interactions, Taj Pharmaceutical Crizotinib contraindications, Crizotinib price, Crizotinib Taj Pharma Crizotinib SmPC-Taj Pharma Stay connected to all updated on Crizotinib Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SMPC.
Bisacodyl 5 mg gastro resistant tablets smpc- taj pharmaceuticalsTaj Pharma
Bisacodyl Uses, Side Effects -: Indications, Side Effects, Warnings, Bisacodyl - Drug Information - Taj Pharma, Bisacodyl dose Taj pharmaceuticals Bisacodyl interactions, Taj Pharmaceutical Bisacodyl contraindications, Bisacodyl price, Bisacodyl Taj Pharma Bisacodyl 5 mg Gastro-resistant Tablets SMPC- Taj Pharma . Stay connected to all updated on Bisacodyl Taj Pharmaceuticals Taj pharmaceuticals Hyderabad
Zoledronic acid 4 mg 100 ml solution for infusion smpc taj pharmaceuticalsTaj Pharma
ZOLEDRONIC ACID Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, ZOLEDRONIC ACID Dosage & Rx Info | ZOLEDRONIC ACID Uses, Side Effects -: Indications, Side Effects, Warnings, ZOLEDRONIC ACID - Drug Information - Taj Pharma, ZOLEDRONIC ACID dose Taj pharmaceuticals ZOLEDRONIC ACID interactions, Taj Pharmaceutical ZOLEDRONIC ACID contraindications, ZOLEDRONIC ACID price, ZOLEDRONIC ACID Taj Pharma Zoledronic acid 4 mg/100 ml Solution For InfusionSMPC- Taj Pharma . Stay connected to all updated on ZOLEDRONIC ACID Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Diclofenac sodium 50mg gastro resistant tablets smpc- taj pharmaceuticalsTaj Pharma
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Albendazole 400 mg tablets smpc taj pharmaceuticalsTaj Pharma
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Cyclophosphamide injection 500 mg inj smpc taj pharmaceuticalsTaj Pharma
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Amiloride hydrochloride 2.5mg and 25mg hydrochlorothiazide tablets smpc taj ...Taj Pharma
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Clopidogrel 75 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
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Beprin 5,000 i.u.ml solution for injection smpc taj pharmaceuticalsTaj Pharma
Beprin (Heparin) Taj Pharma : Uses, Side Effects, Interactions, Pictures, Warnings, Beprin (Heparin) Dosage & Rx Info | Beprin (Heparin) Uses, Side Effects -: Indications, Side Effects, Warnings, Beprin (Heparin) - Drug Information - Taj Pharma, Beprin (Heparin) dose Taj pharmaceuticals Beprin (Heparin) interactions, Taj Pharmaceutical Beprin (Heparin) contraindications, Beprin (Heparin) price, Beprin (Heparin) Taj Pharma Beprin (Heparin) Solution for Injection 5000IU/ml 1000IU/ml SMPC- Taj Pharma . Stay connected to all updated on Beprin (Heparin) Taj Pharmaceuticals Taj pharmaceuticals Hyderabad.
Rabeprazole 20mg gastro resistant tablets smpc- taj pharmaceuticalsTaj Pharma
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Metoclopramide hydrochloride 10 mg tablets smpc taj pharmaceuticalsTaj Pharma
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Captopril Tablets SmPC Taj PharmaceuticalsTajPharmaQC
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Kaptin antidiarrheal susp patient information leafletPharmacia1 .com
Kaptin is an antidiarrheal suspension composed of light kaolin and pectin that treats mild to moderate acute diarrhea and helps control chronic diarrhea. Kaolin adsorbs bacteria and toxins while pectin's mechanism is unknown but stools appear more formed. Kaptin is not absorbed and over 90% of pectin decomposes in the gastrointestinal tract. It is taken after loose bowel movements in doses depending on age. Precautions should be taken with dehydration, parasites, or bloody stools and antibiotics may be needed. It can reduce absorption of some other drugs if taken within a few hours.
Similar to Colecalciferol 20,000 iu capsules smpc taj pharmaceuticals (20)
Zolpiderm tartrate 5mg and 10mg tablets pil, taj pharmaceuticals.Taj Pharma
This document is a patient information leaflet for Zolpidem Tartrate 5mg and 10mg tablets produced by Taj Pharmaceuticals. It provides information on:
- What zolpidem is and what it is used for, which is the short-term treatment of insomnia.
- Contraindications and warnings for its use, including not taking it if you have breathing problems or a history of substance abuse.
- How to take zolpidem, including only taking it at bedtime for 2-4 weeks as prescribed by your doctor.
- Possible side effects and drug interactions to be aware of when taking zolpidem with other medications.
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Tramadol 50mg per ml solution for injection or infusion smpc taj pharmaceuti...Taj Pharma
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Tetracycline hydrochloride 250mg tablets smpc taj pharmaceuticalsTaj Pharma
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Tadalafil 20 mg film coated tablets smpc- taj pharmaceuticalsTaj Pharma
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Quinine sulfate 200mg tablets smpc taj pharmaceuticalsTaj Pharma
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Prednisolone acetate 1% eye drops suspension smpc taj pharmaceuticalsTaj Pharma
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Piperaquine tetraphosphate 320 mg and dihydroartemisinin 40 mg film coated ta...Taj Pharma
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Paracetamol 10mg per ml solution for infusion pil, taj pharmaceuticals.Taj Pharma
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Paracetamol 10 mg per ml solution for infusion smpc taj pharmaceuticalsTaj Pharma
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Oxytetracycline 250mg tablets smpc taj pharmaceuticalsTaj Pharma
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Omeprazole 20mg gastro resistant capsules smpc taj pharmaceuticalsTaj Pharma
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Norfloxacin 400 mg film coated tablet smpc- taj pharmaceuticals (autosaved)Taj Pharma
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Colecalciferol 20,000 iu capsules smpc taj pharmaceuticals
1. Colecalciferol 20 000 IU Capsules SMPC, Taj Phar maceuticals
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RX
COLECALCIFEROL
HARD CAPSULES
20,000 IU
1.NAME OF THE MEDICINAL PRODUCT
Colecalciferol 20,000 IU Capsules, hard
capsules.
2. QUALITATIVE AND QUANTITATIVE
COMPOSITION
Each hard capsule contains:
20 000 IU colecalciferol (equivalent to 500 μg
vitamin D3)
For a full list of excipients, see section 6.1.
3. PHARMACEUTICAL FORM
Capsule, Hard
Ivory opaque, unprinted, hard gelatin capsule
containing a clear, slightly yellow oily liquid.
4. CLINICAL PARTICULARS
4.1 Therapeutic indications
Initial treatment of clinically relevant vitamin D
deficiency in adults.
4.2 Posology and method of administration
One capsule contains 20 000 IU colecalciferol
(vitamin D3).
• Adult posology
Initial treatment of clinically relevant vitamin D
deficiency:
• 1 capsule twice per week (equivalent to 40,000
IU/week) for 7 weeks (corresponding to a
loading dose of 280,000 IU).
Maintenance therapy with lower doses of
vitamin D equivalent to 800 to 1000 IU daily
may be considered one month after the end of
initial treatment with Cholecalciferol 20,000 IU.
For this purpose other preparations are available.
The doctor in charge shall decide on the
individual dosage and the duration of treatment.
• Paediatric population
Colecalciferol 20,000 IU should not be used in
infants or young children (under 12 years) as
they may not be able to swallow the capsules
and might choke. Instead, it is advisable to use
drops or dissolvable tablets. Due to the lack of
data on posology the administration in
adolescents between the ages of 12 – 18 years is
not recommended.
Patients with renal impairment/hypercalcaemia
In the event of hypercalcaemia or signs of
reduced renal function, the dose must be reduced
or the treatment discontinued. If hypercalciuria
occurs (more than 7.5 mmol equivalent to 300
mg calcium/24 hours), the dose is to be reduced
or treatment discontinued.
Method of administration
This medicine is taken orally.
The capsule should be swallowed whole with
water, preferably with the main meal of the day.
4.3 Contraindications
Colecalciferol 20 000 IU Capsules must not be
used in patients with:
• Hypersensitivity to the active substance
(Colecalciferol) or to any of the excipients listed
in section 6.1
• Hypercalcaemia and/or hypercalciuria
• Pseudohypoparathyroidism (The vitamin D
requirement may be reduced by intermittent
normal vitamin D sensitivity, with the risk of
prolonged overdose)
• Nephrolithiasis (Renal calculi)
• Hypervitaminosis D
• Severe renal impairment
• Additional intake of preparations containing
vitamin D
4.4 Special Warnings and precautions for use
Colecalciferol 20 000 IU Capsules should be
used with caution in patients with impairment of
renal function and the effect on calcium and
phosphate levels should be monitored. The risk
of soft tissue calcification should be taken into
account. In patients with severe renal
2. Colecalciferol 20 000 IU Capsules SMPC, Taj Phar maceuticals
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insufficiency, vitamin D in the form of
colecalciferol is not metabolised normally and
other forms of vitamin D have to be be used.
Colecalciferol 20 000 IU Capsules should not be
taken by patients with a tendency to form
calcium-containing renal calculi.
Caution is required in patients receiving
treatment for cardiovascular disease (see section
4.5 – cardiac glycosides including digitalis).
Colecalciferol 20 000 IU Capsules should be
prescribed with caution to patients suffering
from sarcoidosis because of the risk of increased
metabolism of vitamin D to its active form.
These patients should be monitored with regard
to the calcium content in serum and urine.
During pregnancy, Colecalciferol 20,000 IU
should be taken only when strictly indicated and
dosed only as it is absolutely necessary to
correct vitamin D deficiency (see section 4.6).
Allowances should be made for vitamin D
supplements, other vitamin D containing
medicines or from other sources.
The need for additional calcium supplementation
should be considered for individual patients.
Calcium supplements should be given under
close medical supervision.
During treatment with an equivalent daily dose
exceeding 1,000 IU vitamin D the serum and
renal calcium levels must be monitored and
renal function checked via serum creatinine
determination. Such monitoring is particularly
important in elderly patients and during
concomitant treatment with cardiac glycosides
or diuretics (see section 4.5). This also applies to
patients who are particularly susceptible to the
formation of kidney stones that contain calcium.
Paediatric population
Colecalciferol 20,000 IU should not be used in
infants or young children (under 12 years) as
they may not be able to swallow the capsules
and might choke. Instead, it is advisable to use
drops or dissolvable tablets. Due to the lack of
data on posology the administration in
adolescents between the ages of 12-18 years is
not recommended.
4.5 Interaction with other medicinal products
and other forms of interaction
Patients treated with cardiac glycosides may be
susceptible to high calcium levels and should
have ECG parameters and calcium levels
monitored. It is recommended to reduce the dose
or interrupt treatment if the calcium content in
the urine exceeds 7.5 mmol/24 hours (300
mg/24 hours).
Simultaneous administration of benzothiadiazine
derivatives (thiazide diuretics) increases the risk
of hypercalcaemia because they decrease the
calcium excretion in the urine. The calcium
levels in plasma and urine should therefore be
monitored for patients undergoing long-term
treatment.
If colecalciferol is combined with metabolites or
analogues of vitamin D careful monitoring of
serum calcium levels is recommended.
Calcium Supplements (see section 4.4)
Anti-convulsants e.g. phenytoin, phenobarbital,
primidone may diminish the effect of
colecalciferol due to hepatic enzyme induction.
Rifampicin may reduce the effectiveness of
colecalciferol due to hepatic enzyme induction.
Isoniazid may reduce the effectiveness of
colecalciferol due to inhibition of the metabolic
activation of cholecalciferol.
Drugs leading to fat malabsorption, e.g. orlistat,
liquid paraffin, colestyramine, may impair the
absorption of colecalciferol.
The cytotoxic agent actinomycin and imidazole
antifungal agents interfere with vitamin D
activity by inhibiting the conversion of 25-
hydroxyvitamin D to 1,25-dihydroxyvitamin D
by the kidney enzyme, 25-hydroxyvitamin D-1-
hydroxylase.
Concomitant use of glucocorticoids can decrease
the effect of vitamin D.
4.6 Fertility, Pregnancy and lactation
Pregnancy
During pregnancy, Cholecalciferol 20,000 IU
should be taken only when strictly indicated and
dosed only as it is absolutely necessary to
3. Colecalciferol 20 000 IU Capsules SMPC, Taj Phar maceuticals
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correct vitamin D deficiency. Overdoses of
vitamin D must be avoided during pregnancy, as
prolonged hypercalcaemia may lead to
retardation of physical and mental development,
supravalvular aortic stenosis and retinopathy in
the child.
Breast-feeding
Colecalciferol and its metabolites are excreted in
breast milk. Overdose in infants induced by
nursing mothers has not been observed.
However, when prescribing additional vitamin D
to a breast-fed child the practitioner should
consider the dose of any additional vitamin D
given to the mother.
Fertility
Normal endogenous levels of vitamin D are not
expected to have any adverse effects on fertility.
4.7 Effects on ability to drive and use
machines
No studies on the effects on the ability to drive
or use machines have been performed.
Colecalciferol has no known side effects that are
likely to affect the ability to drive and use or
operate machines.
4.8 Undesirable Effects
Adverse reactions are listed below, by system
organ class and frequency.
MedDRA
System
Organ Class
Frequency Category
Uncommon (affecting
less than 1 in 100
people)
Rare (affecting less
than 1 in 1000 people)
Metabolism
and nutrition
disorders
Hypercalcaemia
Hypercalciuria
Skin and
Subcutaneous
disorders
Pruritus
Rash
Urticaria
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after
authorisation of the medicinal product is
important. It allows continued monitoring of the
benefit/risk balance of the medicinal product.
4.9 Overdose
Acute or chronic overdose of colecalciferol can
cause hypercalcaemia, an increase in the serum
and urinary concentrations of calcium. The
symptoms of hypercalcaemia are not very
specific and consist of nausea, vomiting,
diarrhoea often in the early stages and later
constipation, anorexia, fatigue, headache,
muscle and joint pain, muscle weakness,
polydipsia, polyuria formation of renal calculi,
nephrocalcinosis, kidney failure, calcification of
soft tissues, changes in ECG measurements,
arrhythmias and pancreatitis. In rare and isolated
cases there are reports that hypercalcaemia is
fatal.
Treatment of overdose
A normalisation of hypercalcaemia due to
vitamin D intoxication lasts several weeks. The
recommendation for the treatment of
hypercalcaemia is the avoidance of any further
administration of vitamin D, including
supplements, dietary intakes and the avoidance
of sunlight. A low calcium or calcium-free diet
can also be considered.
Rehydration and the treatment with diuretics e.g.
furosemide to ensure adequate diuresis should
be considered. Additional treatment with
calcitonin or corticosteroids can also be
considered.
Phosphate infusions should not be administered
to lower hypercalcaemia of hypervitaminosis D
because of the dangers of metastatic
calcification.
5. PHARMACOLOGICAL PROPERTIES
5.1 Pharmacodynamic properties
Pharmacotherapeutic group: Vitamin D and
analogues
Absorption: Colecalciferol is easily absorbed in
the small intestine.
Colecalciferol is produced within the skin under
the influence of UV radiation including sunlight.
In its biologically active form, colecalciferol
stimulates intestinal calcium absorption,
incorporation of calcium into the osteoid, and
release of calcium from bone tissue. In the small
intestine it promotes rapid and delayed calcium
uptake. The passive and active transport of
phosphate is also stimulated. In the kidney, it
inhibits the excretion of calcium and phosphate
by promoting tubular resorption. The production
of parathyroid hormone (PTH) in the
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parathyroids is inhibited directly by the
biologically active form of cholecalciferol. PTH
secretion is inhibited additionally by the
increased calcium uptake in the small intestine
under the influence of biologically active
colecalciferol.
Elimination: Coleclaciferol and other forms of
vitamin D are excreted in faeces and urine.
5.2 Pharmacokinetic properties
The pharmacokinetics of colecalciferol have
been widely studied and are well-known.
Colecalciferol from nutritional sources is almost
completely absorbed from within the gastro-
intestinal tract in the presence of dietary lipids
and bile acids. Colecalciferol is stored in fat
cells and its biological half-life is approximately
50 days.
Colecalciferol is metabolised by microsomal
hydroxylase to form 25-hydroxycolecalciferol
(25(OH)D3, calcidiol), the primary storage form
of vitamin D3. 25(OH)D3 undergoes a secondary
hydroxylation within the kidney to form the
predominant active metabolite 1,25-
hydroxycolecalciferol (1,25(OH)2D3, calcitriol).
The metabolites circulate in the blood bound to a
specific α-globin.
After a single oral dose of colecalciferol, the
maximum serum concentrations of the primary
storage form are reached after approximately 7
days. 25(OH)D3 is then slowly eliminated with
an apparent half-life in serum of about 50 days.
Colecalciferol and its metabolites are excreted
mainly in the bile and faeces.
After high doses of colecalciferol, serum
concentrations of 25(OH)D3 may be increased
for months. Overdose-induced hypercalcaemia
may persist for weeks (see 4.9 "Overdose”).
5.3 Preclinical safety data
Colecalciferol overdosage in animals has been
shown to induce malformations in rats, mice and
rabbits at doses significantly higher than the
human dose. The malformations included
skeletal defects, microcephaly and cardiac
malformations.
At doses equivalent to those used
therapeutically, colecalciferol has no teratogenic
activity.
Colecalciferol has no potential mutagenic or
carcinogenic activity.
6. PHARMACEUTICAL PARTICULARS
6.1 List of excipients
Capsule content
Medium-chain Triglycerides (from vegetable
sources)
Butylated Hydroxytoluene (BHT)
Colloidal silicon dioxide
Capsule shell:
Gelatin
Titanium dioxide (E171)
Yellow iron oxide (E172)
6.2 Incompatibilities
Not applicable
6.3 Shelf life
36 months
6.4 Special precautions for storage
Store below 25°C. Keep the blister in the outer
carton in order to protect from light.
6.5 Nature and contents of container
Opaque, white PVC/PVdC blister packs with
aluminium foil.
Blister packs containing 10, 14, 20, 28, 30, 56,
60, 84 and 100 hard capsules
Not all pack sizes may be marketed.
6.6 Special precautions for disposal and other
handling
No special requirements for disposal. Any
unused product should be disposed of in
accordance with local requirements.
7. MANUFACTURER:
Manufactured in India by:
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TAJ PHARMACEUTICALS LTD.
Mumbai, India
At: 615, GIDC, Kerala, Bavla, Dist. Ahmedabad
438225, Gujarat, INDIA