This study examined the relationship between cognitive flexibility and the Big Five personality traits of openness, conscientiousness, extraversion, agreeableness, and emotional stability in 221 college students. Cognitive flexibility and personality were measured using the Cognitive Flexibility Scale and Ten-Item Personality Inventory. Results found significant positive correlations between cognitive flexibility and extraversion, conscientiousness, emotional stability, and openness to experience. This suggests that personality influences an individual's ability to adapt to changing situations and generate new ideas.