1. Cellular Medicine
Dr. Pradeep Mahajan
Stem Cells Transplant Expert | Founder @ StemRx Bioscience Solutions Pvt, ltd. India

2.  Life Expectancy.
 Future of Medicine – Next 100 years.
 Cellular Medicine – What’s so new?
 Drug Discovery in a dish.
 Organ Shop- fiction or reality?.
 A paradigm shift from traditional medicine
to cellular medicine – New dimensions .
 Cellular medicine and Therapeutic
Applications.

3.  Limitations of proven therapies
 No longer medical science has remained the
domain of only physicians, clinicians .
 Researchers in Regenerative Medicine
developing new protocols.
Gradual increase in Life expectancy

4. Antibiotics
, vaccines
Sanitization
Superstitious

5. Visualize the future of medicine in next 100
years

6.  Future of medicine – next 100 years
Tele-medicine-
• Internets Skype
• Virtual consultations
• Satellite – Robotic/ diagnostics
•Google Mirror –Using Sensor technology
with hardware & Software with internet
•Holographic consultations with doctors
Digital Medicine-
• I phones
• Digitalization of histopathology
• Brain computed chips
• Artificial augmented limbs
Robotic Medicine-
• Robotic Minimal invasive surgeries
• Robotic tele assisted surgeries
• Intelligent autonomous robotic surgeries
with high speed & resolution MRI
• I-knives with cancer therapies

7. Cancer- No more Mystery- Cancer gene
Chemotherapy, Radiotherapy- Non specific
Patient specific , organ specific & disease specific
personalized therapy
• DNA chips
• Nanoparticles – Magnetic/ Antibody
Cell Based Therapies
• DC cells
• T cells
• NK cells

8. Genomic & Molecular Medicine-
Gene is software Protein is hardware
• Genetic engineering
• Proteomics
• Nanotechnology- applications in
•Cancer
•Metabolic and
•Genetic diseases

9. Man made Macro
Machines
Nature made Nano
Machines
Electric Fence Membrane
Transporters Hb
Digital database Nucleus
Bulldozers Proteosomes
Control centers Centrosomes
Chain couplers Ligase
Internet Nodes Neural System
“ About 1000 years ago, humans domesticated plants
and animals….now its time to domesticate molecules”

10. Cellular Medicine coupled with digital medicine, telemedicine
, nanomedicine can create wonders………
-Use of miraculous stem cells
-Advanced applications of stem
cells
-Curative medicine
The first major revolution……..
Its not the science fiction – It’s the stem
cells research……

11. “ Hope and dreams for stem cells – we live in a
time where the word impossible and unsolvable
are no longer part scientific communities
vocabulary. Each day we move closer to trials that
will not just minimize the symptoms of diseases
and injuries but eliminate them”
- Christopher
Reeve
( Superman )
In fact he introduced stem cells research legacy
to the world
Imagine……….

12.  Research
 Dolly the Sheep
 Ethical & Social Issues

13.  Invention of IPSC’s – Reprogramming of somatic skin
cells,
Embryonic Transcription factors : Oct4, Sox2, KLF4,
Cmyc
 Developing all 220 types of cells.
“ Its not a science fiction . Its stem cells research led to
never before in the history of medical science. Such a
gift received to humans – Stem Cells- which can
regenerate the cells  to tissue to the organs”

14. Somatic cells/ Stem
Cells
Transplanted back
iPSC/ Stem Cells
Culture
Differentiation

15.  Dustan & Haffman ( 1960 )
 Biodegradable scaffolds (2012)
 Body Organ Shop

16. Future is organ development in a
dish!!!!
Breakthrough achievement in organ
transplant……

17.  The technologies for organ development
1. 3D printing technology
2. Scanner technology
3.Cadaver organs like liver, kidney by
washing out cellular material

18. Cells Scaffolds
Regenerative
Medicine
Grafts
Bioengineering and repair of the damaged tissue
with the help of cells in scaffolds

21. Bone Marrow Aspiration
Adipose Tissue Aspiration
Harvesting of stem
cells
Injecting Cells
inside the body
Stem Cells to differentiate and
form different tissues and
organs

22. Cellular Medicine & Robotics
Cellular Medicine & Genomics
Cellular Medicine & Proteom

23.  VSEL’s
 T – Regulatory cells
 EPC
 NK,T, DC
 T-Regulatory
 Cytokines- Micro-medicine
And many more…………

25. Therapeutic Applications of Cellular
Medicine………

27.  More than 4000 patients treated
 One of the leader in therapeutic
applications of stem cells
 Full equipped facility for sample
processing, research and quality control
 Trained laboratory and clinical personnel
 Conducting PhD/ M.Sc courses in Stem
cells in collaboration with ITM
 Currently working on several research
projects covering most of the clinical
disorder in human being

28.  T-regulatory cell Therapy for immune
modulation .
 Applications of Vsel cell.
 Cytokines and growth hormones for oral
and injectable therapies.
 DC T-cell and NK Cell therapies .

29. “ So many of our dreams at first looked
impossible …then improvable …but when we
summon the will , they soon become
inevitable..”