cloning with example and ethical aspects along with advantages and disadvantages of mentioned practice. furthermore social, religious and moral point of views are also discussed.
Cloning, types and challenges
What types of cloning have been successful?
What are the Three Types of Cloning?
Human Cloning: The Good and The Bad
Ethical Issues regarding Human Reproductive Cloning
Challenges
Global and Religious Views
Final Thought
Animal cloning involves transferring the nucleus of a donor adult cell into an egg cell to produce a genetic copy. While cloning can be used for genetic preservation and research, it raises ethical concerns about animal welfare and reducing genetic diversity. Cloning is an inefficient process that often results in pregnancy failures and health issues for cloned animals. Strict regulations are needed to balance the ethical treatment of animals with scientific advancements in cloning technology.
There are three main types of cloning: gene cloning, reproductive cloning, and therapeutic cloning. Gene cloning involves collecting DNA fragments from an organism and cloning them into vectors. Reproductive cloning produces a genetic duplicate of an existing organism, like Dolly the sheep. It is opposed by some due to safety and ethical concerns. Therapeutic cloning creates embryonic stem cells which researchers hope to use to grow healthy tissues to replace damaged or diseased ones. Cloning offers both potential medical benefits like organ transplants and stem cell therapies, as well as risks like uncertainty in the process, inheriting diseases, and potential for abuse. Any discussion on cloning must consider both its value and inherent risks.
This document provides an overview of biotechnology and various applications. It discusses cloning in animals and plants. Reproductive cloning involves transferring the nucleus of an adult cell into an egg with its nucleus removed. Recombinant DNA technology transfers DNA fragments between organisms. Stem cells can replicate and form complex structures, and may help treat medical conditions. The document outlines the cloning of various animal species over time. It also discusses cloning endangered species, human cloning for therapeutic purposes, and the in vitro fertilization process.
This document discusses stem cell research and cloning. It begins with the history of stem cell research and defines different types of stem cells. It then discusses where stem cells come from and the potential benefits of stem cell research. The document also provides an overview of cloning, including important milestones in cloning research. It notes some issues related to stem cell research and cloning, such as religious, medical, and ethical concerns. In conclusion, it states that stem cells may provide future treatment options, and while cloning technology has advanced, it remains controversial.
Introduction
History
Cell culture techniques
Species cloned
Approaches of cell cloning
Monolayer culture- Dilution cloning
Microtitration plate
Suspension culture- Cloning in agar
Cloning in methocel
Isolation of clone
By clonal rings
By suspension clone
Application of cell cloning
Conclusion
Reference
Cloning is the process of producing genetically identical individuals of an organism either naturally or artificially. Natural cloning occurs through asexual reproduction in bacteria, insects, and plants. Artificial cloning involves techniques used to clone DNA fragments, cells, or whole organisms. The first animal cloned was a frog in 1952. In 1996, Dolly the sheep was the first mammal cloned from an adult cell. Cloning works by transferring the nucleus of a donor adult cell into an egg cell with its nucleus removed. Potential benefits include species preservation and medical research applications like organ transplants. However, cloning faces ethical concerns and technical challenges like low success rates and premature aging.
Cloning, types and challenges
What types of cloning have been successful?
What are the Three Types of Cloning?
Human Cloning: The Good and The Bad
Ethical Issues regarding Human Reproductive Cloning
Challenges
Global and Religious Views
Final Thought
Animal cloning involves transferring the nucleus of a donor adult cell into an egg cell to produce a genetic copy. While cloning can be used for genetic preservation and research, it raises ethical concerns about animal welfare and reducing genetic diversity. Cloning is an inefficient process that often results in pregnancy failures and health issues for cloned animals. Strict regulations are needed to balance the ethical treatment of animals with scientific advancements in cloning technology.
There are three main types of cloning: gene cloning, reproductive cloning, and therapeutic cloning. Gene cloning involves collecting DNA fragments from an organism and cloning them into vectors. Reproductive cloning produces a genetic duplicate of an existing organism, like Dolly the sheep. It is opposed by some due to safety and ethical concerns. Therapeutic cloning creates embryonic stem cells which researchers hope to use to grow healthy tissues to replace damaged or diseased ones. Cloning offers both potential medical benefits like organ transplants and stem cell therapies, as well as risks like uncertainty in the process, inheriting diseases, and potential for abuse. Any discussion on cloning must consider both its value and inherent risks.
This document provides an overview of biotechnology and various applications. It discusses cloning in animals and plants. Reproductive cloning involves transferring the nucleus of an adult cell into an egg with its nucleus removed. Recombinant DNA technology transfers DNA fragments between organisms. Stem cells can replicate and form complex structures, and may help treat medical conditions. The document outlines the cloning of various animal species over time. It also discusses cloning endangered species, human cloning for therapeutic purposes, and the in vitro fertilization process.
This document discusses stem cell research and cloning. It begins with the history of stem cell research and defines different types of stem cells. It then discusses where stem cells come from and the potential benefits of stem cell research. The document also provides an overview of cloning, including important milestones in cloning research. It notes some issues related to stem cell research and cloning, such as religious, medical, and ethical concerns. In conclusion, it states that stem cells may provide future treatment options, and while cloning technology has advanced, it remains controversial.
Introduction
History
Cell culture techniques
Species cloned
Approaches of cell cloning
Monolayer culture- Dilution cloning
Microtitration plate
Suspension culture- Cloning in agar
Cloning in methocel
Isolation of clone
By clonal rings
By suspension clone
Application of cell cloning
Conclusion
Reference
Cloning is the process of producing genetically identical individuals of an organism either naturally or artificially. Natural cloning occurs through asexual reproduction in bacteria, insects, and plants. Artificial cloning involves techniques used to clone DNA fragments, cells, or whole organisms. The first animal cloned was a frog in 1952. In 1996, Dolly the sheep was the first mammal cloned from an adult cell. Cloning works by transferring the nucleus of a donor adult cell into an egg cell with its nucleus removed. Potential benefits include species preservation and medical research applications like organ transplants. However, cloning faces ethical concerns and technical challenges like low success rates and premature aging.
Cloning is the process of creating a genetically identical copy of an organism. The document outlines the history of cloning experiments from sea urchins in 1894 to Dolly the sheep in 1996. It describes the main types as DNA cloning, reproductive cloning, and therapeutic cloning. Reproductive cloning aims to create copies of existing organisms while therapeutic cloning produces stem cells for medical research. The document discusses advantages like maintaining good genetics in animals, risks like low success rates and health issues in clones, and applications in biomedical research and livestock breeding.
Cloning is the process of creating a genetically identical copy of an organism. The document outlines the history of cloning experiments from sea urchins in 1894 to Dolly the sheep in 1996. It describes the main types as DNA cloning, reproductive cloning, and therapeutic cloning. Reproductive cloning aims to create copies of existing organisms while therapeutic cloning produces stem cells for medical research. The document discusses advantages like maintaining good genetics in animals, risks like low success rates and health issues in clones, and applications in biomedical research and livestock breeding.
Dr. B. Victor is a retired biology professor with over 32 years of experience teaching and researching reproductive technology in fishes. His presentation outlines various forms of reproduction including asexual, sexual, and parthenogenesis. It also discusses cloning technology such as embryo splitting, nuclear transfer, and the three main types of cloning - recombinant DNA cloning, reproductive cloning, and therapeutic cloning. The benefits and applications of cloning as well as techniques for transgenic animal production are also summarized.
Cloning Essay
Essay about The Pros and Cons of Cloning
Is Cloning Good Or Harmful? Essay
Cloning Essay
Animal Cloning Essay
Cloning Essay
Cloning Essay examples
Persuasive Essay On Cloning
Essay on Cloning
Benefits of Cloning Essay examples
Essay on Human Cloning
Cloning Persuasive Essay
Cloning involves producing genetically identical individuals through asexual reproduction. There are three main types of cloning: gene cloning to copy DNA fragments, cell cloning to duplicate cells, and organism cloning to replicate whole organisms. The cloning process involves inserting the gene of interest into a vector, transforming the vector into a host, and expressing the cloned gene. While cloning has potential medical benefits like creating stem cells or animal disease models, it also raises ethical issues regarding individuality, consent, and reducing genetic diversity.
Dolly the sheep was the first cloned mammal, born in 1996 in Scotland. She was cloned from the mammary gland cells of an adult Finn Dorset sheep using somatic cell nuclear transfer. The nucleus from the donor mammary cell was fused with an egg cell whose nucleus had been removed. Of 277 fused cells, 29 developed further after being implanted into surrogate mothers, resulting in the birth of Dolly. Dolly lived until 2003 and showed that cloning of an adult mammal is possible by nuclear reprogramming.
This document discusses the history and current state of cloning technology. It begins with early cloning experiments on frogs in 1952 and discovery of DNA structure in 1953. Major milestones include the first IVF baby in 1978, cloning of human embryos in 1993, and Dolly the sheep in 1996. While cloning of animals has potential for preserving endangered species and developing medical treatments, human reproductive cloning raises ethical concerns about genetic harm, altered relationships, and commodification of human life. The document examines debates around therapeutic versus reproductive cloning and regulations in different countries.
Genetic engineering allows scientists to directly modify an organism's genes to enhance traits. Examples include crops with increased pest resistance or modified oil content. Cloning organisms is also possible by splitting an early embryo into cells or transferring a cell nucleus into an unfertilized egg. Mutations in human genes occur naturally and can be inherited, unlike artificial changes through genetic engineering. Recombinant DNA techniques have been used to create bacteria that produce human insulin, growth hormone, and vaccines. Dolly the sheep was the first mammal cloned from an adult cell, providing evidence that somatic cell nuclear transfer can recreate a whole organism. While genetic engineering has benefits like curing diseases, some argue it is unethical and should be banned due to
This document discusses bioethics issues involved in cloning. It begins by defining bioethics and the different types of cloning technologies, including recombinant DNA technology, reproductive cloning, and therapeutic cloning. Reproductive cloning aims to generate an organism with the same nuclear DNA as another, while therapeutic cloning destroys embryos to harvest stem cells. The document outlines various bioethical considerations that must be addressed for cloning research, including risks, consent, and respect for subjects. It discusses specific ethical issues around animal cloning, human cloning, and religious and legal perspectives on cloning. Overall, the summary provides a high-level overview of the key bioethics topics related to cloning technologies.
This document provides information about animal cloning, including its history, processes, examples of cloned animals, and ethical issues. It discusses the three main types of cloning - reproductive cloning, gene cloning, and therapeutic cloning. Reproductive cloning aims to produce genetically identical copies of animals and was used to create Dolly the sheep in 1996, the first mammal cloned from an adult somatic cell. While cloning may help protect endangered species and improve livestock, it also raises ethical concerns about technical safety, personal identity, and the commercialization of life.
Reproductive cloning involves transferring the nucleus of a donor adult cell into an egg cell that has had its nucleus removed. The cloned embryo is then implanted into a surrogate mother. Dolly the sheep, born in 1996, was the first mammal cloned using this method. The document discusses the process used to create Dolly, involving transferring the nucleus of an adult sheep cell into an enucleated sheep egg cell. While cloning has potential advantages like organ replacement, cloned animals often exhibit abnormalities and there are ethical concerns about cloning humans.
This document discusses cloning endangered and extinct animal species. It provides background on cloning, including the history of cloning important animals like Dolly the sheep. The document outlines some of the pros of cloning endangered species, such as preserving their unique genetic code and boosting wild populations. However, it also notes some cons, such as low cloning success rates, health issues in clones, and reducing genetic diversity. The overall goal of cloning endangered species is to help preserve them and further scientific understanding.
This document discusses the ethical issues surrounding cloning. It begins by introducing the different types of cloning: gene cloning, reproductive cloning, and therapeutic cloning. It then discusses both the advantages and disadvantages of cloning. The main ethical issues presented are that cloning could close future possibilities, is considered unnatural, and risks abuse. The document concludes by stating that while cloning has potential medical benefits, there are also serious risks and ethical concerns that must be considered before legalizing it.
The document discusses different types of cloning technologies including DNA cloning, reproductive cloning, and therapeutic cloning. DNA cloning involves transferring a DNA fragment from one organism to a self-replicating vector like a bacterial plasmid to generate multiple copies. Reproductive cloning aims to generate an animal with the same nuclear DNA as another through somatic cell nuclear transfer, while therapeutic cloning seeks to produce human embryos for stem cell research. Both cloning techniques are controversial due to safety and ethical concerns.
Cloning animals is an inefficient process with low success rates. While cloning could help endangered species, there are health risks for cloned animals such as large offspring syndrome. Cloning is also expensive and cloned animals may die from defects. However, cloning could provide organs for transplants and help improve animal breeding. Cloning the first sheep Dolly showed it was possible to produce clones from adult cells.
Cloning involves creating genetically identical copies of living organisms. Early cloning experiments in the 1900s involved separating sea urchin and salamander embryos. In 1952, frogs were successfully cloned using nuclear transfer. John Gurdon furthered this research in 1962 by cloning tadpoles using differentiated intestinal cells. His work demonstrated that specialized cells could be reprogrammed. Dolly the sheep, born in 1996, was the first mammal cloned from an adult somatic cell, proving nuclear transfer could produce viable offspring. Cloning research continues to provide insights into development and genetics while also having applications for producing therapies.
Cloning involves the production of genetically identical individuals through asexual reproduction. Molecular cloning involves amplifying identical copies of DNA molecules using living organisms. The key steps of molecular cloning are fragmentation of DNA, ligation of DNA pieces in a desired sequence, transformation of cells by inserting new DNA, and selection of successfully transfected cells. Cloning has potential benefits but also risks, and human reproductive cloning remains controversial.
Cloning is the process of creating a genetically identical copy of an organism. The document outlines the history of cloning experiments from sea urchins in 1894 to Dolly the sheep in 1996. It describes the main types as DNA cloning, reproductive cloning, and therapeutic cloning. Reproductive cloning aims to create copies of existing organisms while therapeutic cloning produces stem cells for medical research. The document discusses advantages like maintaining good genetics in animals, risks like low success rates and health issues in clones, and applications in biomedical research and livestock breeding.
Cloning is the process of creating a genetically identical copy of an organism. The document outlines the history of cloning experiments from sea urchins in 1894 to Dolly the sheep in 1996. It describes the main types as DNA cloning, reproductive cloning, and therapeutic cloning. Reproductive cloning aims to create copies of existing organisms while therapeutic cloning produces stem cells for medical research. The document discusses advantages like maintaining good genetics in animals, risks like low success rates and health issues in clones, and applications in biomedical research and livestock breeding.
Dr. B. Victor is a retired biology professor with over 32 years of experience teaching and researching reproductive technology in fishes. His presentation outlines various forms of reproduction including asexual, sexual, and parthenogenesis. It also discusses cloning technology such as embryo splitting, nuclear transfer, and the three main types of cloning - recombinant DNA cloning, reproductive cloning, and therapeutic cloning. The benefits and applications of cloning as well as techniques for transgenic animal production are also summarized.
Cloning Essay
Essay about The Pros and Cons of Cloning
Is Cloning Good Or Harmful? Essay
Cloning Essay
Animal Cloning Essay
Cloning Essay
Cloning Essay examples
Persuasive Essay On Cloning
Essay on Cloning
Benefits of Cloning Essay examples
Essay on Human Cloning
Cloning Persuasive Essay
Cloning involves producing genetically identical individuals through asexual reproduction. There are three main types of cloning: gene cloning to copy DNA fragments, cell cloning to duplicate cells, and organism cloning to replicate whole organisms. The cloning process involves inserting the gene of interest into a vector, transforming the vector into a host, and expressing the cloned gene. While cloning has potential medical benefits like creating stem cells or animal disease models, it also raises ethical issues regarding individuality, consent, and reducing genetic diversity.
Dolly the sheep was the first cloned mammal, born in 1996 in Scotland. She was cloned from the mammary gland cells of an adult Finn Dorset sheep using somatic cell nuclear transfer. The nucleus from the donor mammary cell was fused with an egg cell whose nucleus had been removed. Of 277 fused cells, 29 developed further after being implanted into surrogate mothers, resulting in the birth of Dolly. Dolly lived until 2003 and showed that cloning of an adult mammal is possible by nuclear reprogramming.
This document discusses the history and current state of cloning technology. It begins with early cloning experiments on frogs in 1952 and discovery of DNA structure in 1953. Major milestones include the first IVF baby in 1978, cloning of human embryos in 1993, and Dolly the sheep in 1996. While cloning of animals has potential for preserving endangered species and developing medical treatments, human reproductive cloning raises ethical concerns about genetic harm, altered relationships, and commodification of human life. The document examines debates around therapeutic versus reproductive cloning and regulations in different countries.
Genetic engineering allows scientists to directly modify an organism's genes to enhance traits. Examples include crops with increased pest resistance or modified oil content. Cloning organisms is also possible by splitting an early embryo into cells or transferring a cell nucleus into an unfertilized egg. Mutations in human genes occur naturally and can be inherited, unlike artificial changes through genetic engineering. Recombinant DNA techniques have been used to create bacteria that produce human insulin, growth hormone, and vaccines. Dolly the sheep was the first mammal cloned from an adult cell, providing evidence that somatic cell nuclear transfer can recreate a whole organism. While genetic engineering has benefits like curing diseases, some argue it is unethical and should be banned due to
This document discusses bioethics issues involved in cloning. It begins by defining bioethics and the different types of cloning technologies, including recombinant DNA technology, reproductive cloning, and therapeutic cloning. Reproductive cloning aims to generate an organism with the same nuclear DNA as another, while therapeutic cloning destroys embryos to harvest stem cells. The document outlines various bioethical considerations that must be addressed for cloning research, including risks, consent, and respect for subjects. It discusses specific ethical issues around animal cloning, human cloning, and religious and legal perspectives on cloning. Overall, the summary provides a high-level overview of the key bioethics topics related to cloning technologies.
This document provides information about animal cloning, including its history, processes, examples of cloned animals, and ethical issues. It discusses the three main types of cloning - reproductive cloning, gene cloning, and therapeutic cloning. Reproductive cloning aims to produce genetically identical copies of animals and was used to create Dolly the sheep in 1996, the first mammal cloned from an adult somatic cell. While cloning may help protect endangered species and improve livestock, it also raises ethical concerns about technical safety, personal identity, and the commercialization of life.
Reproductive cloning involves transferring the nucleus of a donor adult cell into an egg cell that has had its nucleus removed. The cloned embryo is then implanted into a surrogate mother. Dolly the sheep, born in 1996, was the first mammal cloned using this method. The document discusses the process used to create Dolly, involving transferring the nucleus of an adult sheep cell into an enucleated sheep egg cell. While cloning has potential advantages like organ replacement, cloned animals often exhibit abnormalities and there are ethical concerns about cloning humans.
This document discusses cloning endangered and extinct animal species. It provides background on cloning, including the history of cloning important animals like Dolly the sheep. The document outlines some of the pros of cloning endangered species, such as preserving their unique genetic code and boosting wild populations. However, it also notes some cons, such as low cloning success rates, health issues in clones, and reducing genetic diversity. The overall goal of cloning endangered species is to help preserve them and further scientific understanding.
This document discusses the ethical issues surrounding cloning. It begins by introducing the different types of cloning: gene cloning, reproductive cloning, and therapeutic cloning. It then discusses both the advantages and disadvantages of cloning. The main ethical issues presented are that cloning could close future possibilities, is considered unnatural, and risks abuse. The document concludes by stating that while cloning has potential medical benefits, there are also serious risks and ethical concerns that must be considered before legalizing it.
The document discusses different types of cloning technologies including DNA cloning, reproductive cloning, and therapeutic cloning. DNA cloning involves transferring a DNA fragment from one organism to a self-replicating vector like a bacterial plasmid to generate multiple copies. Reproductive cloning aims to generate an animal with the same nuclear DNA as another through somatic cell nuclear transfer, while therapeutic cloning seeks to produce human embryos for stem cell research. Both cloning techniques are controversial due to safety and ethical concerns.
Cloning animals is an inefficient process with low success rates. While cloning could help endangered species, there are health risks for cloned animals such as large offspring syndrome. Cloning is also expensive and cloned animals may die from defects. However, cloning could provide organs for transplants and help improve animal breeding. Cloning the first sheep Dolly showed it was possible to produce clones from adult cells.
Cloning involves creating genetically identical copies of living organisms. Early cloning experiments in the 1900s involved separating sea urchin and salamander embryos. In 1952, frogs were successfully cloned using nuclear transfer. John Gurdon furthered this research in 1962 by cloning tadpoles using differentiated intestinal cells. His work demonstrated that specialized cells could be reprogrammed. Dolly the sheep, born in 1996, was the first mammal cloned from an adult somatic cell, proving nuclear transfer could produce viable offspring. Cloning research continues to provide insights into development and genetics while also having applications for producing therapies.
Cloning involves the production of genetically identical individuals through asexual reproduction. Molecular cloning involves amplifying identical copies of DNA molecules using living organisms. The key steps of molecular cloning are fragmentation of DNA, ligation of DNA pieces in a desired sequence, transformation of cells by inserting new DNA, and selection of successfully transfected cells. Cloning has potential benefits but also risks, and human reproductive cloning remains controversial.
Embracing Deep Variability For Reproducibility and Replicability
Abstract: Reproducibility (aka determinism in some cases) constitutes a fundamental aspect in various fields of computer science, such as floating-point computations in numerical analysis and simulation, concurrency models in parallelism, reproducible builds for third parties integration and packaging, and containerization for execution environments. These concepts, while pervasive across diverse concerns, often exhibit intricate inter-dependencies, making it challenging to achieve a comprehensive understanding. In this short and vision paper we delve into the application of software engineering techniques, specifically variability management, to systematically identify and explicit points of variability that may give rise to reproducibility issues (eg language, libraries, compiler, virtual machine, OS, environment variables, etc). The primary objectives are: i) gaining insights into the variability layers and their possible interactions, ii) capturing and documenting configurations for the sake of reproducibility, and iii) exploring diverse configurations to replicate, and hence validate and ensure the robustness of results. By adopting these methodologies, we aim to address the complexities associated with reproducibility and replicability in modern software systems and environments, facilitating a more comprehensive and nuanced perspective on these critical aspects.
https://hal.science/hal-04582287
Microbial interaction
Microorganisms interacts with each other and can be physically associated with another organisms in a variety of ways.
One organism can be located on the surface of another organism as an ectobiont or located within another organism as endobiont.
Microbial interaction may be positive such as mutualism, proto-cooperation, commensalism or may be negative such as parasitism, predation or competition
Types of microbial interaction
Positive interaction: mutualism, proto-cooperation, commensalism
Negative interaction: Ammensalism (antagonism), parasitism, predation, competition
I. Mutualism:
It is defined as the relationship in which each organism in interaction gets benefits from association. It is an obligatory relationship in which mutualist and host are metabolically dependent on each other.
Mutualistic relationship is very specific where one member of association cannot be replaced by another species.
Mutualism require close physical contact between interacting organisms.
Relationship of mutualism allows organisms to exist in habitat that could not occupied by either species alone.
Mutualistic relationship between organisms allows them to act as a single organism.
Examples of mutualism:
i. Lichens:
Lichens are excellent example of mutualism.
They are the association of specific fungi and certain genus of algae. In lichen, fungal partner is called mycobiont and algal partner is called
II. Syntrophism:
It is an association in which the growth of one organism either depends on or improved by the substrate provided by another organism.
In syntrophism both organism in association gets benefits.
Compound A
Utilized by population 1
Compound B
Utilized by population 2
Compound C
utilized by both Population 1+2
Products
In this theoretical example of syntrophism, population 1 is able to utilize and metabolize compound A, forming compound B but cannot metabolize beyond compound B without co-operation of population 2. Population 2is unable to utilize compound A but it can metabolize compound B forming compound C. Then both population 1 and 2 are able to carry out metabolic reaction which leads to formation of end product that neither population could produce alone.
Examples of syntrophism:
i. Methanogenic ecosystem in sludge digester
Methane produced by methanogenic bacteria depends upon interspecies hydrogen transfer by other fermentative bacteria.
Anaerobic fermentative bacteria generate CO2 and H2 utilizing carbohydrates which is then utilized by methanogenic bacteria (Methanobacter) to produce methane.
ii. Lactobacillus arobinosus and Enterococcus faecalis:
In the minimal media, Lactobacillus arobinosus and Enterococcus faecalis are able to grow together but not alone.
The synergistic relationship between E. faecalis and L. arobinosus occurs in which E. faecalis require folic acid
SDSS1335+0728: The awakening of a ∼ 106M⊙ black hole⋆Sérgio Sacani
Context. The early-type galaxy SDSS J133519.91+072807.4 (hereafter SDSS1335+0728), which had exhibited no prior optical variations during the preceding two decades, began showing significant nuclear variability in the Zwicky Transient Facility (ZTF) alert stream from December 2019 (as ZTF19acnskyy). This variability behaviour, coupled with the host-galaxy properties, suggests that SDSS1335+0728 hosts a ∼ 106M⊙ black hole (BH) that is currently in the process of ‘turning on’. Aims. We present a multi-wavelength photometric analysis and spectroscopic follow-up performed with the aim of better understanding the origin of the nuclear variations detected in SDSS1335+0728. Methods. We used archival photometry (from WISE, 2MASS, SDSS, GALEX, eROSITA) and spectroscopic data (from SDSS and LAMOST) to study the state of SDSS1335+0728 prior to December 2019, and new observations from Swift, SOAR/Goodman, VLT/X-shooter, and Keck/LRIS taken after its turn-on to characterise its current state. We analysed the variability of SDSS1335+0728 in the X-ray/UV/optical/mid-infrared range, modelled its spectral energy distribution prior to and after December 2019, and studied the evolution of its UV/optical spectra. Results. From our multi-wavelength photometric analysis, we find that: (a) since 2021, the UV flux (from Swift/UVOT observations) is four times brighter than the flux reported by GALEX in 2004; (b) since June 2022, the mid-infrared flux has risen more than two times, and the W1−W2 WISE colour has become redder; and (c) since February 2024, the source has begun showing X-ray emission. From our spectroscopic follow-up, we see that (i) the narrow emission line ratios are now consistent with a more energetic ionising continuum; (ii) broad emission lines are not detected; and (iii) the [OIII] line increased its flux ∼ 3.6 years after the first ZTF alert, which implies a relatively compact narrow-line-emitting region. Conclusions. We conclude that the variations observed in SDSS1335+0728 could be either explained by a ∼ 106M⊙ AGN that is just turning on or by an exotic tidal disruption event (TDE). If the former is true, SDSS1335+0728 is one of the strongest cases of an AGNobserved in the process of activating. If the latter were found to be the case, it would correspond to the longest and faintest TDE ever observed (or another class of still unknown nuclear transient). Future observations of SDSS1335+0728 are crucial to further understand its behaviour. Key words. galaxies: active– accretion, accretion discs– galaxies: individual: SDSS J133519.91+072807.4
Dr. Firoozeh Kashani-Sabet is an innovator in Middle Eastern Studies and approaches her work, particularly focused on Iran, with a depth and commitment that has resulted in multiple book publications. She is notable for her work with the University of Pennsylvania, where she serves as the Walter H. Annenberg Professor of History.
JAMES WEBB STUDY THE MASSIVE BLACK HOLE SEEDSSérgio Sacani
The pathway(s) to seeding the massive black holes (MBHs) that exist at the heart of galaxies in the present and distant Universe remains an unsolved problem. Here we categorise, describe and quantitatively discuss the formation pathways of both light and heavy seeds. We emphasise that the most recent computational models suggest that rather than a bimodal-like mass spectrum between light and heavy seeds with light at one end and heavy at the other that instead a continuum exists. Light seeds being more ubiquitous and the heavier seeds becoming less and less abundant due the rarer environmental conditions required for their formation. We therefore examine the different mechanisms that give rise to different seed mass spectrums. We show how and why the mechanisms that produce the heaviest seeds are also among the rarest events in the Universe and are hence extremely unlikely to be the seeds for the vast majority of the MBH population. We quantify, within the limits of the current large uncertainties in the seeding processes, the expected number densities of the seed mass spectrum. We argue that light seeds must be at least 103 to 105 times more numerous than heavy seeds to explain the MBH population as a whole. Based on our current understanding of the seed population this makes heavy seeds (Mseed > 103 M⊙) a significantly more likely pathway given that heavy seeds have an abundance pattern than is close to and likely in excess of 10−4 compared to light seeds. Finally, we examine the current state-of-the-art in numerical calculations and recent observations and plot a path forward for near-future advances in both domains.
Evaluation and Identification of J'BaFofi the Giant Spider of Congo and Moke...MrSproy
ABSTRACT
The J'BaFofi, or "Giant Spider," is a mainly legendary arachnid by reportedly inhabiting the dense rain forests of
the Congo. As despite numerous anecdotal accounts and cultural references, the scientific validation remains more elusive.
My study aims to proper evaluate the existence of the J'BaFofi through the analysis of historical reports,indigenous
testimonies and modern exploration efforts.
BIRDS DIVERSITY OF SOOTEA BISWANATH ASSAM.ppt.pptxgoluk9330
Ahota Beel, nestled in Sootea Biswanath Assam , is celebrated for its extraordinary diversity of bird species. This wetland sanctuary supports a myriad of avian residents and migrants alike. Visitors can admire the elegant flights of migratory species such as the Northern Pintail and Eurasian Wigeon, alongside resident birds including the Asian Openbill and Pheasant-tailed Jacana. With its tranquil scenery and varied habitats, Ahota Beel offers a perfect haven for birdwatchers to appreciate and study the vibrant birdlife that thrives in this natural refuge.
2. Introduction
■ Cloning, the process of generating a genetically identical copy of a cell or an
organism.
■ Cloning happens all the time in nature—for example, when a cell replicates itself
asexually without any genetic alteration or recombination.
■ Cloning is used to produce proteins, vaccines, and antibiotics.
■ Cloning in agriculture is used to produce pest-resistant plants.
■ Cloning is also used for gene therapy and producing transgenic animals.
3. Dolly sheep
experiment
1996
Dolly the sheep was successfully cloned in 1996
by fusing the nucleus from a mammary-gland
cell of a Finn Dorset ewe into an enucleated
egg cell taken from a Scottish Blackface ewe.
Carried to term in the womb of another Scottish
Blackface ewe, Dolly was a genetic copy of the
Finn Dorset ewe
4. Types of cloning
■ Gene cloning, which creates copies of genes or segments of DNA.
■ Reproductive cloning, which creates copies of whole animals.
■ Therapeutic cloning, which creates embryonic stem cells.
5.
6. Benefits of cloning
■ It removes the barrier of infertility.
■ It could extend human life capabilities
■ It could restore balance to families.
■ create tissue and organs that doctors can use when needed for surgery on the
original
7. Drawbacks of cloning
■ It comes with a degree of uncertainty as of yet.
■ It is expected to bring about new diseases.
■ It might lead to problems in organ rejection.
■ It decreases gene diversity.
■ In-Breeding.
■ It can lead to disruption of parenting and family life.
■ It can cause a further divide.
8. Ethical controversy
■ The ethics of cloning refers to a variety of ethical positions regarding the practice
and possibilities of cloning, especially human cloning.
■ While many of these views are religious in origin, some of the questions raised by
cloning are faced by secular perspectives as well.
■ Perspectives on human cloning are theoretical, as human therapeutic and
reproductive cloning are not commercially used; animals are currently cloned in
laboratories and in livestock production.
9. Advocates’ view
Advocates support the development of therapeutic cloning in order to
■ generate tissues and whole organs to treat patients
■ to avoid the need for immunosuppressive drugs
■ stave off the effects of aging.
■ parents who cannot otherwise procreate should have access to technology.
10. Opponents’ view
Opponents of cloning have concerns that
■ technology is not yet developed enough to be safe, and that
■ it could be prone to abuse, either in the form of clones raised as slaves, or leading
to the generation of human farming
■ Organ harvesting
■ concerns about how cloned individuals could integrate with families and with
society at large.
11. Religious point of view
■ The Islamic Fiqh Academy, in its 1997 meeting, agreed that cloning does not
contradict the Islamic faith.
■ God is the creator of the Universe and therefore the advancing knowledge and
technology development that has made cloning possible was pre-ordained by God
Almighty’s will.
12. World point of view
■ Eight-in-ten American adults (81%) say cloning a human being is not morally
acceptable, according to a May 2016 Gallup poll.
■ There has been overwhelming opposition to human cloning since 2001.
■ Just 13% of adults in 2016 say cloning is morally acceptable.