Classification of receptor family and molecular structure of ligand gated ion channels
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This document discusses different types of receptor families and ligand gated ion channels. It describes how ligand gated ion channels work, noting that when ligands bind to these channels, it causes an increase or decrease in ions like sodium, calcium, and potassium. This ion flux leads to either an excitatory or inhibitory effect in the cell or tissue. The presentation provides classifications of receptors and discusses G-protein coupled receptors, enzyme linked receptors, and nuclear receptors. It aims to explain the molecular structure and classification of ligand gated ion channels.
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The International Journal of Engineering & Science would take much care in making your article published without much delay with your kind cooperation.
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- 1. CLASSIFICATION OF RECEPTOR FAMILY AND MOLECULAR STRUCTURE OF LIGAND GATED ION CHANNELS PRESENTED BY: IMADULLA BAIG (18PP118) UNDER THE GUIDANCE OF MR. T.SHEKSHAWALI NATIONAL COLLEGE OF PHARMACY, SHIMOGA
- 2. • INTRODUCTION • G-PROTEIN COUPLED RECEPTORS • ENZYME LINKED RECEPTORS • CLASSIFICATION OF RECEPTORS • NUCLEAR RECEPTORS • LIGAND GATED ION CHANNELS
- 8. LIGAND RECEPTOR ACTIVATION OF SECONDARY MESSENGERS CELL/TISSUE RESPONSE
- 10. ON BINDING OF THESE LIGANDS, FROM THE INTRACELLULAR DOMAIN ENZYME KINASE GETS ACTIVATED WHICH PHOSPHORLYATES THE TYROSINE RESIDUES PRESENT ONTHE INTRACELLULAR DOMAIN THEN THESE PHOSPHOPTYROSINE RESIDUES BIND TO SH2 DOMAIN OF VARIETY OF INTRACELLULAR PROTEINS WHICH FURTHUR PROCESS THE RESPECTIVE CELLULAR FUNCTION.
- 12. ACTIVATED ADENYLATE CYCLASE SECONDARY MESSENGER CYCLIC AMP ACTIVATED CELL/TISSUE RESPONSE
- 15. (LIGAND)
- 16. INCREASE IN NA+ AND CA+ IONS CAUSE EXCITORY EFFECT DECREASE IN IN NA+ AND CA+ IONS CAUSE INHIBITORY EFFECT INCREASE INK + ION CAUSES INHIBITORY EFFECT DECREASE IN K+ ION CAUSES EXCITORY EFFECT