Wound healing involves a cascade of biological events that results in a closed wound. There are different types of wound healing depending on the depth and severity of the wound. The normal wound healing process consists of three main phases - inflammation, proliferation, and remodeling. Many factors can affect wound healing including the characteristics of the wound and patient as well as how the wound is managed and dressed. Proper wound assessment and choosing the right dressing are important for optimizing the healing process.
This topic is mainly for MBBS Studnts. It is under the General Principles of Surgery. Students shoud know the phases of wound healing so as to treat them appropriately and select the correct method of dressing material....
This topic is mainly for MBBS Studnts. It is under the General Principles of Surgery. Students shoud know the phases of wound healing so as to treat them appropriately and select the correct method of dressing material....
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
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QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
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2. What is ‘Wound Healing’
• Cascade of immunologic and biologic events resulting in a closed
wound
• Acute wounds proceed through the processes involved in wound
healing in an orderly and timely manner
• Chronic wounds fail to heal in a timely and orderly manner
• Viability of tissues will determine the course and quality of healing
4. Superficial Wound Healing
• Ulcerations in the superficial skin
• Soft tissues heal themselves over time via inflammatory repair
process
• I.e. stage I pressure ulcer, superficial burn, or contusion
5. Primary Intention Wound Healing
• • A.k.a. Surgical wound healing
• Connective tissue deposition and epithelialization
• No granulation tissue formation or wound contraction
6. Delayed Primary Intention
• Wound left open to:
• Promote drainage • Reduce bacterial burden
• Later (often within seven days) surgically closed
7. Partial Thickness Wound Healing
• Wounds with loss of the epidermis or partial thickness skin loss of the
dermis
• Heal by epithelialization/regeneration
• Wound edges
• Dermal appendages
• Normal appearance and function
• I.e. abrasions, skin tears, stage II pressure ulcers, blisters, and partial
thickness burn
8. Full Thickness/Secondary Intention Healing
• Most effective method when:
• The wound extends through all
layers of skin
• High microorganism count
• Debris or non-viable tissue
present
9. Full Thickness/Secondary Intention Healing
• Involves inflammation,
epithelialization, proliferation, and
remodeling
• Scar tissue formation and contraction
• Replacement tissue will have less
elasticity/tensile strength
10.
11. Chronic Wound Healing
• Associated with secondary intention
• A chronic wound is one that has “failed to proceed though an orderly
and timely process to produce anatomic and functional integrity, or
proceeded through the repair process without establishing a
sustained anatomic and functional result”
12. Wound Healing Phases
• Every wound is unique, “with a unique set of physiologic and
social circumstances preventing or retarding wound healing”
• The normal wound repair process consists of three phases that
occur in a predictable sequence : ▫ Inflammation ▫ Proliferation ▫
Remodeling
17. Wound characteristics
• Exudate
• Odour
• Condition of tissue
within the wound
• Condition of the
surrounding skin
The surrounding skin
Eczema
Psoriasis
Maceration/excoriation
due to exudate or
bowel contents
Self-inflicted damage
18. Monitoring healing progress
• Wound dimensions
• Photography
Wound assessment
charts
Frequency of
assessment
Plan of care
Useful information
Other methods
19. Dressing choice
• What is available?
• How do we choose?
• Does the patient have a say?
• Do we consider cost?
• Are choices restricted by a protocol?
• How do we evaluate?
20. Dressing choice
The purpose of
dressings:
•To aid debridement
•To remove excess
exudate
•To control bleeding
•To protect a wound
•To support healing
The ideal dressing
A dressing that
creates the optimum
environment
Wound debridement
Wound cleansing
Alternative therapies
22. Dressing choice
Film dressings
•Semi-permeable primary or secondary
dressings
•Clear polyurethane coated with adhesive
•Conformable, resistant to shear and tear
•Do not absorb exudate
•Examples: Tegaderm, Op-site.
23. Dressing choice
Hydrocolloids
• Pectin, gelatin, carboxymethylcellulose and
elastomers
• Environment for autolysis to debride sloughy or
necrotic wounds
• Occlusive --> hypoxic environment to
encourage angiogenesis
• Waterproof
• Different presentations e.g. Urgotul
