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  Standard                                                                                                                                  Stock Report as of Sep 27, 2010

         Cipher Pharmaceuticals Inc (DND-T)
         Mississauga, ON, Canada (905) 602-5840 www.cipherpharma.com


         Share Price                                                                   $1.25                       Market Cap (Mil)                                       $30.10
         52 Week High                                                                  $1.84                       Cash (Mil)                                             $10.31
         52 Week Low                                                                   $0.43                       Total Debt (Mil)                                         $0.00
         Avg Vol Last 3 mos. (000's)                                                     1.76                      Enterprise Value (Mil)                                 $30.10
         Basic Shares Outstanding (Mil)                                                24.08                       Dividend Yield                                           0.0%
         Diluted Shares Outstanding (Mil)                                              25.86                       P/E (TTM)                                                    NA


         Stock Price and Volume                                                                                    Business Description                          Source: Morningstar


                                                                                                                   Cipher Pharmaceuticals Inc. is a drug development
          900,000                                                                        $1.80
                                                                                                                   company focused on commercializing formulations of
          800,000                                                                        $1.60                     marketed molecules using advanced drug delivery
                                                                                                                   technologies. The Company in-licenses products that
          700,000                                                                        $1.40                     incorporate drug delivery technologies and advance them
                                                                                                                   through the clinical development and regulatory approval
          600,000                                                                        $1.20
                                                                                                                   stages, after which the products will be out-licensed to
                                                                                                Stock Price

                                                                                                                   international partners.      CIP-FENOFIBRATE       has been
Volume




          500,000                                                                        $1.00
                                                                                                                   approved in the United States and Canada under the
          400,000                                                                        $0.80                     trademarks Lipofen and Fenomax, respectively. CIP-
                                                                                                                   TRAMADOL ER has received approval from the United
          300,000                                                                        $0.60                     States Food and Drug Administration (FDA). CIP-
                                                                                                                   ISOTRETINOIN’s application has been filed and is pending
          200,000                                                                        $0.40
                                                                                                                   FDA approval subject to successful completion of a safety
          100,000                                                                        $0.20                     study. CIP-FENOFIBRATE is a formulation of the active
                                                                                                                   ingredient   fenofibrate used      in the treatment of
               -                                                                         $-                        hyperlipidemia, a cholesterol disorder. CIP-ISOTRETINOIN
                    S O N D J    F M A M J     J A S O N D J      F M A M J    J A S                               is a formulation of the active ingredient isotretinoin used in
                         2008                   2009                  2010                                         the treatment of severe acne.

                                                                                                                                                          Comparables
         Scorecard Highlights                                                                                                                                    DDS-T
         Ratings Out of Possible 5 Stars                                                                                                                         NRI-T
                                                                                                                                                                  YM-T
                                                                             Quarter Ending Jun               10       Quarter Ending Mar   10


         Stock Market Performance
                                                                                       2.7                                      1.2                               1.9


         Insider Ownership
                                                                                       4.6                                Not Provided                     Not Provided


         Revenue, EBITDA and EPS
                                                                                       3.6                                      3.5                               1.8


         Balance Sheet Analysis
                                                                                       3.5                                      4.5                               4.3


         Return on Capital
                                                                                       0.4                                      0.3                               1.6


         Valuation
                                                                                       2.8                                      4.1                               3.7
  © 2010 The Equicom Group Inc.  All rights reserved. The Investor Scorecard is exclusively distributed by TMX Equicom. To learn more visit www.tmxmoney.com/scorecard
  For a full description of the methodology used, refer to www.fsavaluation.com/scorecardinformation.aspx
  Please see the final page(s) of this Investor Scorecard for important disclosure and disclaimer information.
investorSCOREcard
Cipher Pharmaceuticals (DND-T)

Company Profile

Cipher is a commercial-stage specialty pharmaceutical company that develops improved formulations of existing
drugs.


Cipher’s focus is the clinical and regulatory development of novel pharmaceutical products. Cipher’s core
competency is identifying these product opportunities and managing their clinical and regulatory development. At or
near final regulatory approval, the company harvests the rewards by out-licensing to international partners and
generating royalty streams. Because Cipher’s products are based on currently marketed drugs, they are expected to
have lower approval risk, shorter development timelines and significantly lower development costs compared with
new chemical entities.




Business Model




Cipher was founded in 2000 as the pharmaceutical division of CML Healthcare (TSX: CLC.UN). Cipher was spun out
as a separate public entity in 2004 when CML converted to an income trust.
investorSCOREcard
Cipher Pharmaceuticals (DND-T)

Product Portfolio

Cipher has three products in its portfolio. Lipofen® is currently on the U.S. market; CIP-TRAMADOL ER
received final approval from the United States Food & Drug Administration (FDA) and is expected to be
launched in H1 2011; CIP-ISOTRETINOIN is in its final Phase III safety study and is expected to be
launched in the U.S. in 2012. The company continues to evaluate new opportunities to bring into its
pipeline with the objective of in-licensing at least one new product each year.



        NAME          INDICATION           DESCRIPTION                          STATUS
  Lipofen®            Hyperlipidemia       Novel, patented formulation of       Launched in U.S. market in
                      (high cholesterol)   the active ingredient fenofibrate,   Q4 2007.
                                           used to manage elevated
                                           triglycerides and cholesterol        Partnered with Kowa
                                           levels.                              Pharmaceuticals America.

                                                                                Product royalties continue
                                                                                to increase.
  CIP-                Severe acne          Novel, patented formulation of       FDA approvable letter.
  ISOTRETINOIN                             isotretinoin.                        Partnered with Ranbaxy
                                                                                Pharmaceuticals Inc. for
                                           CIP-ISOTRETINOIN provides            the U.S. market.
                                           more consistent absorption
                                           under variable dietary conditions    Pivotal phase III safety
                                           compared with existing               study underway; expected
                                           isotretinoin products on the         to be completed in H1
                                           market. This advantage is            2011.
                                           expected to result in enhanced
                                           patient compliance and reduced       Other geographic markets
                                           chance of relapse following the      being evaluated.
                                           standard five-month treatment
                                           period.

  CIP-TRAMADOL        Moderate to          Novel, extended-release              FDA approval in May 2010.
  ER                  moderately severe    formulation of the active
                      pain (e.g.           ingredient tramadol.                 Company is in active
                      osteoarthritis)                                           discussions with
                                           CIP-TRAMADOL ER delivers 24-         prospective partners.
                                           hour coverage with once-daily
                                           dosing, supporting ease-of-use       Currently targeting H1
                                           for physicians and a high level of   2011 for U.S. commercial
                                           compliance among chronic pain        launch.
                                           sufferers.
                                                                                New Drug Submission to
                                           Relative to current once-daily       Health Canada accepted
                                           formulations, Cipher’s product       for review in Q1 2010;
                                           provides fast absorption and has     review expected to be
                                           no food effect.                      completed by early 2011.
investorSCOREcard
Cipher Pharmaceuticals (DND-T)

Management Team

Larry Andrews, President and CEO
   •   Accomplished senior executive with more than 25 years of experience in the pharmaceutical industry.
   •   Former President of AltiMed Pharmaceuticals and Founder and President of the Health Alliance Group.
   •   Has played a lead role in the licensing of more than 25 compounds in the Canadian pharmaceutical market
       and has marketed both innovative and generic products.
   •   Career includes senior management assignments with Eli Lilly, Syntex Pharmaceuticals, and Hoffmann-La
       Roche.


Norman Evans, C.A., Chief Financial Officer
   •   Chartered Accountant with more than 25 years of business experience.
   •   Most recently held the position of Vice-President, Finance at MDS Pharma Services, a division of MDS Inc.
   •   Previously was a Partner in the Toronto office of Ernst & Young.


Jason A. Gross, Pharm.D., Vice President, Scientific Affairs
   •   Dr. Gross has been in the pharmaceutical industry for more than 14 years.
   •   Most recently held the position of Venture Partner and Vice President of Scientific Affairs at MDS Capital
       Corporation, where he served as interim management of investee companies, coordinated and conducted
       scientific due diligence, and provided scientific guidance to MDS Capital’s investee companies.
   •   Previous roles include Vice President of Regulatory Affairs and Quality Assurance for DrugAbuse Sciences
       and Director of State, Federal and International Regulatory Affairs at Zenith/Goldline Pharmaceuticals.
   •   Formerly an officer in the Public Health Service assigned to the U.S. Food and Drug Administration (FDA),
       Center for Drug Evaluation and Research.


John MacInnis, Vice President, Portfolio Development and Licensing
   •   Formerly the Vice President, Business Development at Kromite, a consulting firm that offers strategic
       support to life science companies.
   •   Prior to joining Kromite, served as Executive Vice President, Business Development at DRI Capital, where he
       was responsible for the identification and evaluation of life science royalty financing opportunities.
   •   Has also served as Director, Disease Area Strategy within Novartis Global Marketing (Basel), and Executive
       Director, CNS Franchise within the Strategic Marketing Group at Johnson and Johnson, Inc (USA).
investorSCOREcard
Cipher Pharmaceuticals (DND-T)

Recent Developments/Future Milestones

Q1 2010:     Reached enrolment mid-point of CIP-ISOTRETINOIN Phase III safety trial, which   triggered a US$2.0
             million milestone payment to Cipher from its marketing partner.


Q1 2010:     New Drug Submission for CIP-TRAMADOL ER accepted for review by Health Canada.


Q2 2010:     Achieved final FDA approval for CIP-TRAMADOL ER, the Company’s extended-release tramadol
             product. Represents the Company’s second FDA-approved product.


Q2 2010:     Achievement of a US$1 million commercial milestone for Lipofen®.


Q3 2010:     U.S. patent issued on CIP-TRAMADOL ER.


H2 2010:     Complete licensing partnership for CIP-TRAMADOL ER. Complete enrollment of CIP-ISOTRETINOIN
             Phase III safety study.




Comparables


Labopharm Inc. – DDS-T
Nuvo Research Inc. – NRI-T
YM BioSciences Inc. – YM-T
investorSCOREcard
Cipher Pharmaceuticals Inc (DND-T)

Stock Market Performance Rating                                                                                                                                                                                                                                         2.7


Stock Market Returns                                                                                                   250,000                                                                                                              $5.00

                                                                                                                                                                                                                                            $4.50
                                            Return      Percentile        Rating
                 Three Months                 7%          53%              2.7                                         200,000                                                                                                              $4.00
                   Six Months              (13.8%)        29%              1.4




                                                                                                                                                                                                                                                          Stock Price
                                                                                                                                                                                                                                            $3.50
                        1 Year               116%         100%             5.0




                                                                                                              Volume
               3 Years (CAGR)                 3%          67%              3.3                                         150,000                                                                                                              $3.00
               5 Years (CAGR)               (8.9%)        20%              1.0                                                                                                                                                              $2.50

                                                                                                                       100,000                                                                                                              $2.00
Market Data                                                                                                                                                                                                                                 $1.50
                                      Price             $1.25
                              Mkt Cap (Mil)             $30.10                                                          50,000                                                                                                              $1.00
                     Shs Outstanding (Mil)              24.08                                                                                                                                                                               $0.50
                          Dividend Yield %              0.0%
                                                                                                                              -                                                                                                             $-
                Avg Vol Last 3mos. (000's)              1.76



                                                                                                                                  2004




                                                                                                                                                 2005




                                                                                                                                                                         2006




                                                                                                                                                                                     2007




                                                                                                                                                                                                     2008




                                                                                                                                                                                                                 2009




                                                                                                                                                                                                                             2010
                                 P/E (TTM)               NA




Insider Ownership Rating                                                                                                                                                                                                                                                4.6

Value of Shares and Options                                                                                                                                                                                     Percent of Ownership

                                                 Shares                                    Options                          Total Value Rating           Percent Rating                                                                          40.9% Insiders
                                                                                                          * Adjusted                                                                                                                             18.6% > 10% Holders
                                                                           # of            $ Value if                 Adjusted $
                                          # of Shares    $ Value                                           $ Value if                       Rating       Percent of               Rating                                                         40.5% Other
                                                                          Options          Exercised                    Value
                                                                                                          Exercised                        (Add all)     Mkt. Value              (Add all)
                 Larry Andrews
                                             100,000      $125,000         500,000           $625,000       $312,500          $437,500        0.2             1.4%                  0.3
                   President and CEO
                 Norman Evans
                                              20,000       $25,000         272,500           $340,625       $170,313          $195,313        0.1             0.6%                  0.1          Oct-10
                                  CFO
                    Jason Gross                                                                                                                                                                  Sep-10
                                              25,000       $31,250         487,500           $609,375       $304,688          $335,938        0.1             1.0%                  0.2
                                                                                                                                                                                                 Aug-10
            Board of Directors
                                           9,648,399    $12,060,499        331,446           $414,308       $207,154 $12,267,653              4.0           38.0%                   5.0
                                                                                                                                                                                                 Jul-10

              > 10% Holders                                                                                                                                                                      Jun-10
                                           4,807,100     $6,008,875               -                  $0                $0    $6,008,875                     18.6%
                 For info only
 Total (excl. >10% Holders)                             $18,250,624                        $1,989,308       $994,654 $19,245,278             4.0            40.9%                  4.0                 0%       20%      40%          60%           80%                 100%

                                                                                                                                          (Max of 4)                            (Max of 4)                  CEO                     CFO
                                                                                                                                                                                                            Other Officers          Directors
                                                                                                                                                                                                            > 10% Holders           Public Float

* Adjusted $ Value of Options is 50% of their full value if exercised to account for volatility. Furthermore, our view is that shareholders would rather management owned shares vs. options.


Add: Compensation Type
                                                                         Category                                                                Rating Addition                                              Percent of Compensation
                                                                                                                               Total      Perform- Share and
                                            Salary       Perform-   Share and               Option        All Other           Comp.         ance      Unit       Option
                                                        ance Bonus Unit Awards              Awards         Comp.                           Bonus     Awards     Awards
                                                                                                                                                                                                                         2.2%
                 Larry Andrews                                                                                                                                                                                  7.2%                                      Salary
                                            $353,300      $107,804                            $56,000        $10,569          $527,673       0.25                                  0.25                     0.0%
                   President and CEO                                                                                                                                                                                                                      Bonus
                                                                                                                                                                                                    17.4%
                 Norman Evans                                                                                                                                                                                                                             Shares & Units
                                            $202,000       $43,268                            $21,000         $6,060          $272,328       0.25                                  0.25
                                  CFO                                                                                                                                                                                                                     Options
                    Jason Gross                                                                                                                                                                                                                           All Other
                                            $225,600       $48,730                            $21,000         $6,768          $302,098       0.25                                  0.25
                  VP Scientific Affairs
                                                                                                                                                                                                                                            73.1%
                 John MacInnis
                                            $210,000       $36,477                                            $6,300          $252,777       0.25
            VP Portfolio Development



                               Total        $990,900      $236,279                    $0      $98,000        $29,697         $1,354,876      0.25              0.00                0.25
                                                                                                                                           (Max Score)
Bonus: Net Buying/Selling Last Six Months
                                                                                                                                                                                 Insider Holdings Beginning and Ending Value
                                                        Transactions
                                                                                                                                                          Adjusted Share and




                                                                                                                                                                                 $25,000,000
                                                                                            Rating
                                                                                                                                                             Option Value




                                            Buying        Selling           Net             Bonus                                                                                $20,000,000

                                                                                                                                                                                 $15,000,000
    Larry Andrews, President and CEO         $15,250                $0     $15,250           0.03
                 Norman Evans, CFO                $0                $0          $0           0.00                                                                                $10,000,000
                       Other Officers             $0                $0          $0           0.00
            William Claypool, Director       $29,330                $0     $29,330           0.04
                                                                                                                                                                                   $5,000,000
                Bill Garriock, Director       $6,096                $0      $6,096           0.01                                                                                           $-
           > 10% Holders (info only)              $0                $0          $0
                                                                                                                                                                                                                 Beg     Trans-      Ending
 Total (excl. >10% Holders)                  $44,580                $0     $44,580           0.08         (Total Score)
                                                                                                                                                                                                                 Value   actions      Value
investorSCOREcard

Cipher Pharmaceuticals Inc (DND-T)

Balance Sheet Analysis Rating                                                                                                                                                                                        3.5

Short-Term Liquidity                                                                                                                           Quadrant 3:                                                 Quadrant 1:
                                                                                                                                               "RECOVERING"                                                "OPTIMAL"
                                                                                                                                           $ 4.0




                                                                                                           + VE
This Company's cash flow is considered NOT SEASONAL, therefore this report uses the last
quarter's cash flow multiplied by 4 as a proxy for annual cash flow.
                                                                                                                                           $ 3.0                                                      Jun-10


Quadrant Rating                         Jun-09        Sep-09        Dec-09        Mar-10          Jun-10                                   $ 2.0
Working Capital                          $ 8.8         $ 8.3         $ 7.7         $ 8.9           $ 9.1
Cash Flow Ops (Q in mil)                 ($0.2)        ($0.1)        ($0.2)       ($0.1)           $ 0.7                                   $ 1.0




                                                                                                           Cash Flow
Cash Flow Ops (Ann Q's in mil)           ($1.0)        ($0.3)        ($0.7)       ($0.3)           $ 2.9
                                                                                                                                                                                             Sep-09
Quadrant Rating                           3.0           3.0           3.0           3.0             4.0                                    $-
                                                                                                                                                                                                   Mar-10
                                                                                                                                                                                             Dec-09
Addition to Quadrant Rating                                                                                                                ($1.0)                                                     Jun-09
Our methodology accounts for the 'nearness' to improving or worsening a Company's quadrant
ranking based on current cash generation/burn rate and working capital position. The                                                       ($2.0)


                                                                                                           - VE
Company's short term liquidity situation is OPTIMAL. At the current cash generation rate the
                                                                                                                                                 ($2)   $-           $2       $4        $6     $8      $ 10   $ 12
Company's working capital will double in 38 month(s).                                                                                                                                                    Quadrant 2:
                                                                                                                                                Quadrant 4:
                                                                                                                                                "URGENT"                                           "DRAWING DOWN"
                                                                                       Add:        0.0                                      - VE                          Working Capital                  + VE


Short-Term Liquidity Rating                                                                       4.0

Debt to Equity
                                        Jun-09        Sep-09        Dec-09        Mar-10          Jun-10                                                                                              Utilities
                                                                                                                                                                                                      Telecom
Equity
                                                                                                                     Number of Companies




                                                                                                                                                                                                      Materials
Common Stock Equity                     $ 11.8        $ 11.4        $ 11.0        $ 10.6          $ 11.5                                                                                              Info Tech
                                                                                                                                                                                                      Industrials
Total Equity                            $ 11.8        $ 11.4        $ 11.0        $ 10.6          $ 11.5                                                                                              Health Care
                                                                                                                                                                                                      Energy
                                                                                                                                                                                                      Cons Staples
Debt and Equivalents                                                                                                                                                                                  Cons Disc
Pref. Securities of Sub Trust            -             -             -             -               -
Pref. Equity Outside Stock Equity        -             -             -             -               -
Preferred Stock Equity                   -             -             -             -               -
Minority Interest (Bal. Sheet)           -             -             -             -               -
Short-Term Debt                          -             -             -             -               -
Long-Term Debt                           -             -             -             -               -
Capital Lease Obligations                -             -             -             -               -
Total Debt and Equivalents          $        -    $        -    $        -    $        -      $        -
                                                                                                                                             0.00             1.00            2.00             3.00                  4.00

Debt to Equity                           0.00          0.00          0.00          0.00            0.00
Debt to Equity Rating                                                                              3.0                                      Low Risk                      Debt to Equity                         High Risk


Debt to Equity Rating                                                                             3.0


Interest Coverage
                                        Jun-09        Sep-09        Dec-09        Mar-10          Jun-10                                   1.0 x

EBIT                                                                                                                                       0.9 x
                                                                                                               Interest Coverage




Quarterly                               ($1.0)        ($0.7)        ($0.8)        ($0.7)          $ 0.6                                    0.8 x
TTM                                     ($3.0)        ($3.5)        ($3.6)        ($3.3)          ($1.7)                                   0.7 x




                                                                                                                                                                          N/A
                                                                                                                                           0.6 x
Interest Expense
                                                                                                                                           0.5 x
Quarterly                                -             -             -             -               -
                                                                                                                                           0.4 x
TTM                                      -             -             -             -               -
                                                                                                                                           0.3 x

Interest Coverage                                                                                                                          0.2 x
Quarterly                               #N/A          #N/A          #N/A          #N/A            #N/A                                     0.1 x
TTM                                     #N/A          #N/A          #N/A          #N/A            #N/A
                                                                                                                                           0.0 x

                                                                                                                                                         Jun-09      Sep-09    Dec-09     Mar-10   Jun-10
Interest Coverage Rating
Qtrly Interest Coverage Rating                                                                                                                                                Quarterly
TTM Interest Coverage Rating                                                                                                                                                  TTM


Interest Coverage Rating                                                                          N/A
investorSCOREcard
Cipher Pharmaceuticals Inc (DND-T)

Revenue, EBITDA and EPS Rating                                                                                                                                                                                                              3.6


Revenue (in millions)




                                                                                                               Revenue (in milions) on Rolling TTM
                                                                                                                                                     $6.00


                                                                                                                                                     $5.00
Annual (Fiscal Year)                        Dec-05        Dec-06        Dec-07        Dec-08         Dec-09
Revenue                                      $ 0.8         $ 0.9           $ 0.5        $ 1.5         $ 3.2
                                                                                                                                                     $4.00

Quarterly                                   Jun-09        Sep-09        Dec-09        Mar-10         Jun-10




                                                                                                                              Basis
Quarter Ending                               $ 0.7         $ 1.1           $ 0.8       $ 0.9          $ 2.2                                          $3.00
TTM                                          $ 2.4         $ 2.8           $ 3.2       $ 3.5          $ 5.0
                                                                                                                                                     $2.00
Growth                        Percent       Rating     Stability                         R²         Rating
Rev. Growth % TTM              112.5%         5.0      Revenue Stability TTM           87.5%           4.4                                           $1.00
Rev. Growth % LFY              106.0%         5.0      Revenue Stability Last 2 Yrs    94.0%           4.7
Rev. Growth % 3 Year CAGR                              Revenue Stability Last 3 Yrs                                                                  $-
Rev. Growth % 5 Year CAGR                              Revenue Stability Last 5 Yrs                                                                            Jun      Jun      Jun      Jun         Jun     Jun     Jun     Jun    Jun    Jun
Revenue Growth Rating                         5.0      Overall Revenue Stability Rating                4.5                                                      01       02       03       04          05      06      07      08     09     10


Revenue Growth and Stability Rating                                                                   4.8


EBITDA (in millions)
                                                                                                               EBITDA (in milions) on Rolling TTM




                                                                                                                                                             $-
                                                                                                                                                          ($2.00)
Annual (Fiscal Year)                        Dec-05        Dec-06        Dec-07        Dec-08         Dec-09                                               ($4.00)
EBITDA                                      ($16.5)       ($11.6)          ($6.7)      ($3.3)         ($2.0)
                                                                                                                                                          ($6.00)
                                                                                                                                                          ($8.00)
Quarterly                                   Jun-09        Sep-09        Dec-09        Mar-10         Jun-10
                                                                                                                              Basis




Quarter Ending                               ($0.6)        ($0.3)          ($0.5)      ($0.3)         $ 0.9                                            ($10.00)
TTM                                          ($1.7)        ($2.0)          ($2.0)      ($1.7)         ($0.2)                                           ($12.00)
                                                                                                                                                       ($14.00)
Growth                        Percent       Rating     Stability                         R²         Rating
EBITDA Growth % TTM             87.1%         2.5      EBITDA Stability TTM            44.8%           2.2                                             ($16.00)
EBITDA Growth % LFY             39.0%         2.5      EBITDA Stability Last 2 Yrs     90.0%           4.5                                             ($18.00)
EBITDA Grwth % 3 Yr CAGR        69.6%         2.5      EBITDA Stability Last 3 Yrs     93.3%           4.7                                             ($20.00)
EBITDA Grwth % 5 Yr CAGR        49.4%         2.5      EBITDA Stability Last 5 Yrs     51.7%           2.6                                                           Jun      Jun      Jun      Jun     Jun     Jun     Jun    Jun    Jun    Jun
EBITDA Growth Rating                          2.5      Overall EBITDA Stablitity Rating                3.5                                                            01       02       03       04      05      06      07     08     09     10


EBITDA Growth and Stability Rating                                                                    3.0


Basic Earnings Per Share (EPS*)                                                                                                                           $-
* (excluding acquired in process R&D, restructuring and M&A, special income & charges and discontinued ops)
                                                                                                                                                       ($0.10)
Annual (Fiscal Year)                        Dec-05        Dec-06        Dec-07        Dec-08         Dec-09
                                                                                                               EPS on Rolling TTM




                                                                                                                                                       ($0.20)
EPS                                         ($0.79)       ($0.51)        ($0.27)       ($0.14)       ($0.11)
                                                                                                                                                       ($0.30)

Quarterly (TTM)
                                                                                                                      Basis




                                            Jun-09        Sep-09        Dec-09        Mar-10         Jun-10                                            ($0.40)
Quarter Ending                              ($0.03)       ($0.02)        ($0.02)       ($0.02)       $ 0.03
                                                                                                                                                       ($0.50)
TTM                                         ($0.08)       ($0.11)        ($0.10)       ($0.09)       ($0.03)
                                                                                                                                                       ($0.60)
Growth                        Percent       Rating     Stability                         R²         Rating                                             ($0.70)
EPS Growth % TTM                62.5%         2.5      EPS Stability TTM               36.8%           1.8
EPS Growth % LFY                21.4%         1.9      EPS Stability Last 2 Yrs        88.1%           4.4                                             ($0.80)
EPS Grwth % 3 Year CAGR         54.6%         2.5      EPS Stability Last 3 Yrs        91.1%           4.6                                             ($0.90)
EPS Grwth % 5 Year CAGR         42.3%         2.4      EPS Stability Last 5 Yrs        76.7%           3.8                                                        Jun      Jun      Jun      Jun       Jun     Jun     Jun     Jun    Jun    Jun
EPS Growth Rating                             2.3      Overall EPS Stablitity Rating                   3.7                                                         01       02       03       04        05      06      07      08     09     10


EPS Growth and Stability Rating                                                                       3.0
investorSCOREcard

Cipher Pharmaceuticals Inc (DND-T)

Return On Capital Rating                                                                                                                                                                                 0.4


Return On Invested Capital (ROIC)
                                                                                                                                             0%

Annual (Fiscal Year)                           Dec-05        Dec-06        Dec-07       Dec-08        Dec-09
Invested Capital Period Ending                 $ 22.3        $ 21.5        $ 16.9       $ 14.0        $ 11.3                               (10%)
Average Invested Capital                       $ 27.7        $ 21.9        $ 19.2       $ 15.4        $ 12.7




                                                                                                                     ROIC on Rolling TTM
* Net Income                                   ($16.0)       ($11.6)       ($6.9)       ($3.9)        ($3.5)                               (20%)
Add Back: After Tax Interest Expense       $       -     $       -     $       -    $       -     $       -
Annual ROIC                                    -57.8%        -53.2%        -36.1%       -25.1%        -27.3%
                                                                                                                                           (30%)




                                                                                                                            Basis
Level Rating                                    0.0           0.0           0.0          0.2           0.1
Consistency Rating                                                                                     0.1
                                                                                                                                           (40%)
Quarterly (TTM)                                Jun-09        Sep-09        Dec-09       Mar-10        Jun-10
Invested Capital Period Ending                 $ 12.8        $ 12.1        $ 11.3       $ 12.3        $ 12.7                               (50%)
Average Invested Capital                       $ 13.7        $ 13.3        $ 12.7       $ 12.3        $ 12.2
* Net Income                                   ($2.7)        ($3.5)        ($3.5)       ($3.2)        ($1.6)
                                                                                                                                           (60%)
Add Back: After Tax Interest Expense       $       -     $       -     $       -    $       -     $       -
Quarterly ROIC                                 -19.6%        -25.9%        -27.3%       -25.8%        -13.4%
Level Rating                                    0.4           0.2           0.1          0.2           0.7                                 (70%)
Consistency Rating                                                                                     0.3                                         Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun    Jun
                                                                                                                                                    01    02    03    04    05    06    07    08    09     10


Return on Invested Capital (ROIC) Rating                                                               0.3


Return On Assets (ROA)
                                                                                                                                             0%

Annual (Fiscal Year)                           Dec-05        Dec-06        Dec-07       Dec-08        Dec-09
Total Assets Period Ending                     $ 25.7        $ 22.5        $ 18.7       $ 16.4        $ 14.8
                                                                                                                                           (10%)
Average Total Assets                           $ 32.3        $ 24.1        $ 20.6       $ 17.5        $ 15.6
                                                                                                                     ROA on Rolling TTM




* Net Income                                   ($16.0)       ($11.6)       ($6.9)       ($3.9)        ($3.5)
Add Back: After Tax Interest Expense       $       -     $       -     $       -    $       -     $       -                                (20%)
Annual ROA                                     -49.5%        -48.2%        -33.5%       -22.1%        -22.2%
                                                                                                                           Basis




Level Rating                                    0.0           0.0           0.1          0.4           0.4
Consistency Rating                                                                                     0.2                                 (30%)


Quarterly (TTM)                                Jun-09        Sep-09        Dec-09       Mar-10        Jun-10                               (40%)
Total Assets Period Ending                     $ 15.5        $ 15.4        $ 14.8       $ 16.3        $ 16.9
Average Total Assets                           $ 16.0        $ 15.9        $ 15.4       $ 15.4        $ 15.8
* Net Income                                   ($2.7)        ($3.5)        ($3.5)       ($3.2)        ($1.6)                               (50%)
Add Back: After Tax Interest Expense       $       -     $       -     $       -    $       -     $       -
Quarterly ROA                                  -19.6%        -25.9%        -27.3%       -25.8%        -13.4%
Level Rating                                    0.5           0.3           0.2          0.3           0.9                                 (60%)
Consistency Rating                                                                                     0.4                                         Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun    Jun
                                                                                                                                                    01    02    03    04    05    06    07    08    09     10


Return on Assets (ROA) Rating                                                                          0.5


Return On Common Equity (ROE)
                                                                                                                                             0%

Annual (Fiscal Year)                           Dec-05        Dec-06        Dec-07       Dec-08        Dec-09
Total Equity Period Ending                     $ 22.3        $ 21.5        $ 15.7       $ 13.0        $ 11.0                               (10%)
Average Common Equity                          $ 26.4        $ 21.9        $ 18.6       $ 14.4        $ 12.0
                                                                                                                     ROE on Rolling TTM




* Net Income                                   ($16.0)       ($11.6)       ($6.9)       ($3.9)        ($3.5)                               (20%)
Add Back: NA                               $       -     $       -     $       -    $       -     $       -
Annual ROE                                     -60.7%        -53.2%        -37.2%       -27.0%        -28.8%
                                                                                                                                           (30%)
                                                                                                                           Basis




Level Rating                                    0.0           0.0           0.1          0.4           0.3
Consistency Rating                                                                                     0.2
                                                                                                                                           (40%)
Quarterly (TTM)                                Jun-09        Sep-09        Dec-09       Mar-10        Jun-10
Total Equity Period Ending                     $ 11.8        $ 11.4        $ 11.0       $ 10.6        $ 11.5                               (50%)
Average Common Equity                          $ 12.7        $ 12.4        $ 11.9       $ 11.4        $ 11.2
* Net Income                                   ($2.7)        ($3.5)        ($3.5)       ($3.2)        ($1.6)
                                                                                                                                           (60%)
Add Back: NA                                       -             -             -            -             -
Quarterly ROE                                  -21.1%        -27.8%        -29.0%       -27.8%        -14.6%
Level Rating                                    0.6           0.3           0.3          0.3           0.9                                 (70%)
Consistency Rating                                                                                     0.5                                         Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun    Jun
                                                                                                                                                    01    02    03    04    05    06    07    08    09     10


Return on Common Equity (ROE) Rating                                                                   0.5
* Net Income - Excludes Net Income from Discontinued Operations, Income Acquired in Process R&D, Income Restructuring And M&A, and Other Special Income/(Charges)
investorSCOREcard

Cipher Pharmaceuticals Inc (DND-T)

Valuation Rating                                                                                                                                                                                                         2.8


Price to Earnings (P/E)
                                                                                                                                                           1.0 x
(Lower numbers receive higher rankings)
                                                                                                                                                           0.9 x
Annual (Fiscal Year)                            Dec-05         Dec-06         Dec-07          Dec-08         Dec-09
                                                                                                                                                           0.8 x
* Price                                          $ 4.85         $ 4.40         $ 1.20         $ 0.62         $ 1.15




                                                                                                                                P/E on Rolling TTM
Earnings Per Share (EPS)                        ($0.79)         ($0.51)        ($0.27)        ($0.14)        ($0.11)                                       0.7 x

                                                                                                                                                           0.6 x
Annual P/E




                                                                                                                                       Basis
Annual P/E Rating                                                                                                                                          0.5 x

                                                                                                                                                           0.4 x
Quarterly (TTM)                                 Jun-09         Sep-09         Dec-09          Mar-10         Jun-10
* Price                                          $ 0.75         $ 0.46         $ 1.15         $ 1.17         $ 1.25                                        0.3 x
Earnings Per Share (EPS)                        ($0.08)         ($0.11)        ($0.10)        ($0.09)        ($0.03)                                       0.2 x

Quarterly (TTM) P/E                                                                                                                                        0.1 x
Quarterly (TTM) P/E Rating                                                                                                                                 0.0 x
                                                                                                                                                                   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun    Jun
                                                                                                                                                                    01    02    03    04    05    06    07    08    09     10


Price to Earnings (P/E)                                                                                      N/A


Price to Book (P/Book)
                                                                                                                                                           6.0 x
(Lower numbers receive higher rankings)


Annual (Fiscal Year)                            Dec-05         Dec-06         Dec-07          Dec-08         Dec-09                                        5.0 x
                                                                                                                                P/Book on Quarterly




* Price                                          $ 4.85         $ 4.40         $ 1.20         $ 0.62         $ 1.15
Book Equity Per Share                            $ 1.04         $ 0.89         $ 0.65         $ 0.54         $ 0.46
                                                                                                                                                           4.0 x

Annual P/Book                                    4.6 x           4.9 x          1.8 x          1.1 x          2.5 x
                                                                                                                                       Basis




Annual P/Book Rating                              0.8            0.6             3.6            4.2            2.9                                         3.0 x


Quarterly                                       Jun-09         Sep-09         Dec-09          Mar-10         Jun-10                                        2.0 x
* Price                                          $ 0.75         $ 0.46         $ 1.15         $ 1.17         $ 1.25
Book Equity Per Share                            $ 0.49         $ 0.48         $ 0.46         $ 0.44         $ 0.48
                                                                                                                                                           1.0 x
Quarterly P/Book                                 1.5 x           1.0 x          2.5 x          2.7 x          2.6 x
Quarterly P/Book Rating                           3.9            4.3             2.9            2.7            2.8                                         0.0 x
                                                                                                                                                                   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun    Jun
                                                                                                                                                                    01    02    03    04    05    06    07    08    09     10


Price to Book (P/Book)                                                                                        2.8


Enterprise Value to EBITDA (EV/EBITDA)
                                                                                                                                                           1.0 x
(Lower numbers receive higher rankings)
                                                                                                                                                           0.9 x
                                                                                                                                EV/EBITDA on Rolling TTM




Annual (Fiscal Year)                            Dec-05         Dec-06         Dec-07          Dec-08         Dec-09
                                                                                                                                                           0.8 x
* Enterprise Value                             $ 103.48       $ 105.76        $ 30.06        $ 15.91        $ 27.99
EBITDA                                          ($16.47)       ($11.57)        ($6.74)        ($3.33)        ($2.03)                                       0.7 x

                                                                                                                                                           0.6 x
Annual EV/EBITDA
                                                                                                                                         Basis




Annual EV/EBITDA Rating                                                                                                                                    0.5 x

                                                                                                                                                           0.4 x
Quarterly (TTM)                                 Jun-09         Sep-09         Dec-09          Mar-10         Jun-10
* Enterprise Value                              $ 19.01        $ 11.69        $ 27.99        $ 29.85        $ 30.10                                        0.3 x
EBITDA                                          ($1.68)         ($2.03)        ($2.03)        ($1.74)        ($0.22)                                       0.2 x

Quarterly (TTM) EV/EBITDA                                                                                                                                  0.1 x
Quarterly (TTM) EV/EBITDA Rating                                                                                                                           0.0 x
                                                                                                                                                                   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun   Jun    Jun
                                                                                                                                                                    01    02    03    04    05    06    07    08    09     10


Enterprise Value to EBITDA (EV/EBITDA)                                                                       N/A
* Price - Delayed 60 days to reflect the fact that financial statements are public approximately 60 days after the last day of the reporting period. For the last period the most recent price is used.
investorSCOREcard
Disclosure and Disclaimer
The issuer (“Issuer”) covered under this investor scorecard (“Investor Scorecard”) has paid a fee or has been charged a fee for the
production and distribution of this Investor Scorecard. The fee paid or charged for the production and distribution of this Investor
Scorecard was not subject to the rankings or information provided herein, nor was any securities of the Issuer accepted as
payment for such fee. FSA Financial Science & Art Ltd. (“FSA”), The Equicom Group Inc. (“Equicom”) and their respective
employees and directors may have had or from time to time acquire, hold or sell an interest in the listed securities of the Issuer.
Unless specified otherwise, all forward looking statements in this Investor Scorecard have been approved by the Issuer, and the
Issuer has advised FSA and Equicom, without independent verification by FSA or Equicom that a reasonable basis exists for such
forward looking statements. Other information contained in this Investor Scorecard has been compiled by FSA or Equicom from
sources believed to be reliable, which may include but not limited to, public information, research reports and discussions with
management of the Issuer. Prior to its publication, this Investor Scorecard had been submitted to the management of the Issuer
for review for factual accuracy.
No representation or warranty, express or implied, is made by FSA, Equicom, its affiliates, any other person that provided
information or data for this Investor Scorecard or any person that distributes this Investor Scorecard with respect to the adequacy,
accuracy, completeness or timeliness of any information, estimates or opinions provided in this Investor Scorecard. All estimates,
opinions and other information in this Investor Scorecard are provided by FSA, Equicom or another party as of the date of this
Investor Scorecard. Such estimates, opinions and other information are subject to change without notice, and are provided in
good faith but without any legal responsibility. Past performance is no guarantee of future results.
This Investor Scorecard is provided for informational purposes only and does not constitute an offer or solicitation to buy or sell
any securities discussed herein in any jurisdiction. The securities discussed in this Investor Scorecard may not be eligible for sale in
some jurisdictions. This Investor Scorecard is not, and under no circumstances should be construed as, a solicitation to act as a
securities broker, dealer or advisor in any jurisdiction by any person or company that is not legally permitted to carry on the
business of a securities broker, dealer or advisor in that jurisdiction. Neither FSA nor Equicom is a registered investment dealer,
broker or advisor, has investment banking operations or makes markets in any securities.
This Investor Scorecard is prepared for general circulation and to provide an overview of Issuer’s business. This Investor Scorecard
does not consider the investment objectives, financial situation or particular needs of any particular person, and is not tailored to
the needs of any person receiving this Investor Scorecard. Readers of this Investor Scorecard should obtain professional advice
based on their own individual circumstances before making an investment decision. Nothing in this Investor Scorecard constitutes
individual investment, legal or tax advice. To the fullest extent permitted by law, FSA, Equicom, Morningstar Inc., its content
providers, any other person that has provided information or data for this Investor Scorecard nor any authorized person that
distributes this Investor Scorecard accepts any liability whatsoever for any direct, indirect, special, economic or consequential loss
(whether in contract or tort even if FSA, Equicom or the other party has been advised of the possibility of such loss) arising from
any use of, or reliance on the estimates, opinions or other information contained in this Investor Scorecard.
Without limiting the generality of the foregoing, you are prohibited from using or disclosing any personal information contained in
the Investor Scorecard for purposes unrelated to the purposes for which the information is made available to you and/or the public
under Canadian securities laws, including, without limitation, for secondary marketing purposes, unless you have obtained any and
all consents as required under applicable Canadian privacy laws.
The information contained in this Investor Scorecard is copyrighted, and it may not be sold or licensed for commercial value or
altered, in whole or in part, without prior express written consent of Equicom. Furthermore, Investor Scorecard can only be
distributed in its entirety. Information or data herein, including any trade mark, service mark or logo is the intellectual property of
FSA, Equicom, Morningstar Inc. and/or its content providers, Issuer or other persons that have provided such information or data,
including but not limited to the organizations listed below and their respective content providers.




        This report was produced in part with information from the following organizations:

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Cipher Pharmaceuticals

  • 1. investorSCOREcard Standard Stock Report as of Sep 27, 2010 Cipher Pharmaceuticals Inc (DND-T) Mississauga, ON, Canada (905) 602-5840 www.cipherpharma.com Share Price $1.25 Market Cap (Mil) $30.10 52 Week High $1.84 Cash (Mil) $10.31 52 Week Low $0.43 Total Debt (Mil) $0.00 Avg Vol Last 3 mos. (000's) 1.76 Enterprise Value (Mil) $30.10 Basic Shares Outstanding (Mil) 24.08 Dividend Yield 0.0% Diluted Shares Outstanding (Mil) 25.86 P/E (TTM) NA Stock Price and Volume Business Description Source: Morningstar Cipher Pharmaceuticals Inc. is a drug development 900,000 $1.80 company focused on commercializing formulations of 800,000 $1.60 marketed molecules using advanced drug delivery technologies. The Company in-licenses products that 700,000 $1.40 incorporate drug delivery technologies and advance them through the clinical development and regulatory approval 600,000 $1.20 stages, after which the products will be out-licensed to Stock Price international partners. CIP-FENOFIBRATE has been Volume 500,000 $1.00 approved in the United States and Canada under the 400,000 $0.80 trademarks Lipofen and Fenomax, respectively. CIP- TRAMADOL ER has received approval from the United 300,000 $0.60 States Food and Drug Administration (FDA). CIP- ISOTRETINOIN’s application has been filed and is pending 200,000 $0.40 FDA approval subject to successful completion of a safety 100,000 $0.20 study. CIP-FENOFIBRATE is a formulation of the active ingredient fenofibrate used in the treatment of - $- hyperlipidemia, a cholesterol disorder. CIP-ISOTRETINOIN S O N D J F M A M J J A S O N D J F M A M J J A S is a formulation of the active ingredient isotretinoin used in 2008 2009 2010 the treatment of severe acne. Comparables Scorecard Highlights DDS-T Ratings Out of Possible 5 Stars NRI-T YM-T Quarter Ending Jun 10 Quarter Ending Mar 10 Stock Market Performance 2.7 1.2 1.9 Insider Ownership 4.6 Not Provided Not Provided Revenue, EBITDA and EPS 3.6 3.5 1.8 Balance Sheet Analysis 3.5 4.5 4.3 Return on Capital 0.4 0.3 1.6 Valuation 2.8 4.1 3.7 © 2010 The Equicom Group Inc.  All rights reserved. The Investor Scorecard is exclusively distributed by TMX Equicom. To learn more visit www.tmxmoney.com/scorecard For a full description of the methodology used, refer to www.fsavaluation.com/scorecardinformation.aspx Please see the final page(s) of this Investor Scorecard for important disclosure and disclaimer information.
  • 2. investorSCOREcard Cipher Pharmaceuticals (DND-T) Company Profile Cipher is a commercial-stage specialty pharmaceutical company that develops improved formulations of existing drugs. Cipher’s focus is the clinical and regulatory development of novel pharmaceutical products. Cipher’s core competency is identifying these product opportunities and managing their clinical and regulatory development. At or near final regulatory approval, the company harvests the rewards by out-licensing to international partners and generating royalty streams. Because Cipher’s products are based on currently marketed drugs, they are expected to have lower approval risk, shorter development timelines and significantly lower development costs compared with new chemical entities. Business Model Cipher was founded in 2000 as the pharmaceutical division of CML Healthcare (TSX: CLC.UN). Cipher was spun out as a separate public entity in 2004 when CML converted to an income trust.
  • 3. investorSCOREcard Cipher Pharmaceuticals (DND-T) Product Portfolio Cipher has three products in its portfolio. Lipofen® is currently on the U.S. market; CIP-TRAMADOL ER received final approval from the United States Food & Drug Administration (FDA) and is expected to be launched in H1 2011; CIP-ISOTRETINOIN is in its final Phase III safety study and is expected to be launched in the U.S. in 2012. The company continues to evaluate new opportunities to bring into its pipeline with the objective of in-licensing at least one new product each year. NAME INDICATION DESCRIPTION STATUS Lipofen® Hyperlipidemia Novel, patented formulation of Launched in U.S. market in (high cholesterol) the active ingredient fenofibrate, Q4 2007. used to manage elevated triglycerides and cholesterol Partnered with Kowa levels. Pharmaceuticals America. Product royalties continue to increase. CIP- Severe acne Novel, patented formulation of FDA approvable letter. ISOTRETINOIN isotretinoin. Partnered with Ranbaxy Pharmaceuticals Inc. for CIP-ISOTRETINOIN provides the U.S. market. more consistent absorption under variable dietary conditions Pivotal phase III safety compared with existing study underway; expected isotretinoin products on the to be completed in H1 market. This advantage is 2011. expected to result in enhanced patient compliance and reduced Other geographic markets chance of relapse following the being evaluated. standard five-month treatment period. CIP-TRAMADOL Moderate to Novel, extended-release FDA approval in May 2010. ER moderately severe formulation of the active pain (e.g. ingredient tramadol. Company is in active osteoarthritis) discussions with CIP-TRAMADOL ER delivers 24- prospective partners. hour coverage with once-daily dosing, supporting ease-of-use Currently targeting H1 for physicians and a high level of 2011 for U.S. commercial compliance among chronic pain launch. sufferers. New Drug Submission to Relative to current once-daily Health Canada accepted formulations, Cipher’s product for review in Q1 2010; provides fast absorption and has review expected to be no food effect. completed by early 2011.
  • 4. investorSCOREcard Cipher Pharmaceuticals (DND-T) Management Team Larry Andrews, President and CEO • Accomplished senior executive with more than 25 years of experience in the pharmaceutical industry. • Former President of AltiMed Pharmaceuticals and Founder and President of the Health Alliance Group. • Has played a lead role in the licensing of more than 25 compounds in the Canadian pharmaceutical market and has marketed both innovative and generic products. • Career includes senior management assignments with Eli Lilly, Syntex Pharmaceuticals, and Hoffmann-La Roche. Norman Evans, C.A., Chief Financial Officer • Chartered Accountant with more than 25 years of business experience. • Most recently held the position of Vice-President, Finance at MDS Pharma Services, a division of MDS Inc. • Previously was a Partner in the Toronto office of Ernst & Young. Jason A. Gross, Pharm.D., Vice President, Scientific Affairs • Dr. Gross has been in the pharmaceutical industry for more than 14 years. • Most recently held the position of Venture Partner and Vice President of Scientific Affairs at MDS Capital Corporation, where he served as interim management of investee companies, coordinated and conducted scientific due diligence, and provided scientific guidance to MDS Capital’s investee companies. • Previous roles include Vice President of Regulatory Affairs and Quality Assurance for DrugAbuse Sciences and Director of State, Federal and International Regulatory Affairs at Zenith/Goldline Pharmaceuticals. • Formerly an officer in the Public Health Service assigned to the U.S. Food and Drug Administration (FDA), Center for Drug Evaluation and Research. John MacInnis, Vice President, Portfolio Development and Licensing • Formerly the Vice President, Business Development at Kromite, a consulting firm that offers strategic support to life science companies. • Prior to joining Kromite, served as Executive Vice President, Business Development at DRI Capital, where he was responsible for the identification and evaluation of life science royalty financing opportunities. • Has also served as Director, Disease Area Strategy within Novartis Global Marketing (Basel), and Executive Director, CNS Franchise within the Strategic Marketing Group at Johnson and Johnson, Inc (USA).
  • 5. investorSCOREcard Cipher Pharmaceuticals (DND-T) Recent Developments/Future Milestones Q1 2010: Reached enrolment mid-point of CIP-ISOTRETINOIN Phase III safety trial, which triggered a US$2.0 million milestone payment to Cipher from its marketing partner. Q1 2010: New Drug Submission for CIP-TRAMADOL ER accepted for review by Health Canada. Q2 2010: Achieved final FDA approval for CIP-TRAMADOL ER, the Company’s extended-release tramadol product. Represents the Company’s second FDA-approved product. Q2 2010: Achievement of a US$1 million commercial milestone for Lipofen®. Q3 2010: U.S. patent issued on CIP-TRAMADOL ER. H2 2010: Complete licensing partnership for CIP-TRAMADOL ER. Complete enrollment of CIP-ISOTRETINOIN Phase III safety study. Comparables Labopharm Inc. – DDS-T Nuvo Research Inc. – NRI-T YM BioSciences Inc. – YM-T
  • 6. investorSCOREcard Cipher Pharmaceuticals Inc (DND-T) Stock Market Performance Rating 2.7 Stock Market Returns 250,000 $5.00 $4.50 Return Percentile Rating Three Months 7% 53% 2.7 200,000 $4.00 Six Months (13.8%) 29% 1.4 Stock Price $3.50 1 Year 116% 100% 5.0 Volume 3 Years (CAGR) 3% 67% 3.3 150,000 $3.00 5 Years (CAGR) (8.9%) 20% 1.0 $2.50 100,000 $2.00 Market Data $1.50 Price $1.25 Mkt Cap (Mil) $30.10 50,000 $1.00 Shs Outstanding (Mil) 24.08 $0.50 Dividend Yield % 0.0% - $- Avg Vol Last 3mos. (000's) 1.76 2004 2005 2006 2007 2008 2009 2010 P/E (TTM) NA Insider Ownership Rating 4.6 Value of Shares and Options Percent of Ownership Shares Options Total Value Rating Percent Rating 40.9% Insiders * Adjusted 18.6% > 10% Holders # of $ Value if Adjusted $ # of Shares $ Value $ Value if Rating Percent of Rating 40.5% Other Options Exercised Value Exercised (Add all) Mkt. Value (Add all) Larry Andrews 100,000 $125,000 500,000 $625,000 $312,500 $437,500 0.2 1.4% 0.3 President and CEO Norman Evans 20,000 $25,000 272,500 $340,625 $170,313 $195,313 0.1 0.6% 0.1 Oct-10 CFO Jason Gross Sep-10 25,000 $31,250 487,500 $609,375 $304,688 $335,938 0.1 1.0% 0.2 Aug-10 Board of Directors 9,648,399 $12,060,499 331,446 $414,308 $207,154 $12,267,653 4.0 38.0% 5.0 Jul-10 > 10% Holders Jun-10 4,807,100 $6,008,875 - $0 $0 $6,008,875 18.6% For info only Total (excl. >10% Holders) $18,250,624 $1,989,308 $994,654 $19,245,278 4.0 40.9% 4.0 0% 20% 40% 60% 80% 100% (Max of 4) (Max of 4) CEO CFO Other Officers Directors > 10% Holders Public Float * Adjusted $ Value of Options is 50% of their full value if exercised to account for volatility. Furthermore, our view is that shareholders would rather management owned shares vs. options. Add: Compensation Type Category Rating Addition Percent of Compensation Total Perform- Share and Salary Perform- Share and Option All Other Comp. ance Unit Option ance Bonus Unit Awards Awards Comp. Bonus Awards Awards 2.2% Larry Andrews 7.2% Salary $353,300 $107,804 $56,000 $10,569 $527,673 0.25 0.25 0.0% President and CEO Bonus 17.4% Norman Evans Shares & Units $202,000 $43,268 $21,000 $6,060 $272,328 0.25 0.25 CFO Options Jason Gross All Other $225,600 $48,730 $21,000 $6,768 $302,098 0.25 0.25 VP Scientific Affairs 73.1% John MacInnis $210,000 $36,477 $6,300 $252,777 0.25 VP Portfolio Development Total $990,900 $236,279 $0 $98,000 $29,697 $1,354,876 0.25 0.00 0.25 (Max Score) Bonus: Net Buying/Selling Last Six Months Insider Holdings Beginning and Ending Value Transactions Adjusted Share and $25,000,000 Rating Option Value Buying Selling Net Bonus $20,000,000 $15,000,000 Larry Andrews, President and CEO $15,250 $0 $15,250 0.03 Norman Evans, CFO $0 $0 $0 0.00 $10,000,000 Other Officers $0 $0 $0 0.00 William Claypool, Director $29,330 $0 $29,330 0.04 $5,000,000 Bill Garriock, Director $6,096 $0 $6,096 0.01 $- > 10% Holders (info only) $0 $0 $0 Beg Trans- Ending Total (excl. >10% Holders) $44,580 $0 $44,580 0.08 (Total Score) Value actions Value
  • 7. investorSCOREcard Cipher Pharmaceuticals Inc (DND-T) Balance Sheet Analysis Rating 3.5 Short-Term Liquidity Quadrant 3: Quadrant 1: "RECOVERING" "OPTIMAL" $ 4.0 + VE This Company's cash flow is considered NOT SEASONAL, therefore this report uses the last quarter's cash flow multiplied by 4 as a proxy for annual cash flow. $ 3.0 Jun-10 Quadrant Rating Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 $ 2.0 Working Capital $ 8.8 $ 8.3 $ 7.7 $ 8.9 $ 9.1 Cash Flow Ops (Q in mil) ($0.2) ($0.1) ($0.2) ($0.1) $ 0.7 $ 1.0 Cash Flow Cash Flow Ops (Ann Q's in mil) ($1.0) ($0.3) ($0.7) ($0.3) $ 2.9 Sep-09 Quadrant Rating 3.0 3.0 3.0 3.0 4.0 $- Mar-10 Dec-09 Addition to Quadrant Rating ($1.0) Jun-09 Our methodology accounts for the 'nearness' to improving or worsening a Company's quadrant ranking based on current cash generation/burn rate and working capital position. The ($2.0) - VE Company's short term liquidity situation is OPTIMAL. At the current cash generation rate the ($2) $- $2 $4 $6 $8 $ 10 $ 12 Company's working capital will double in 38 month(s). Quadrant 2: Quadrant 4: "URGENT" "DRAWING DOWN" Add: 0.0 - VE Working Capital + VE Short-Term Liquidity Rating 4.0 Debt to Equity Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 Utilities Telecom Equity Number of Companies Materials Common Stock Equity $ 11.8 $ 11.4 $ 11.0 $ 10.6 $ 11.5 Info Tech Industrials Total Equity $ 11.8 $ 11.4 $ 11.0 $ 10.6 $ 11.5 Health Care Energy Cons Staples Debt and Equivalents Cons Disc Pref. Securities of Sub Trust - - - - - Pref. Equity Outside Stock Equity - - - - - Preferred Stock Equity - - - - - Minority Interest (Bal. Sheet) - - - - - Short-Term Debt - - - - - Long-Term Debt - - - - - Capital Lease Obligations - - - - - Total Debt and Equivalents $ - $ - $ - $ - $ - 0.00 1.00 2.00 3.00 4.00 Debt to Equity 0.00 0.00 0.00 0.00 0.00 Debt to Equity Rating 3.0 Low Risk Debt to Equity High Risk Debt to Equity Rating 3.0 Interest Coverage Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 1.0 x EBIT 0.9 x Interest Coverage Quarterly ($1.0) ($0.7) ($0.8) ($0.7) $ 0.6 0.8 x TTM ($3.0) ($3.5) ($3.6) ($3.3) ($1.7) 0.7 x N/A 0.6 x Interest Expense 0.5 x Quarterly - - - - - 0.4 x TTM - - - - - 0.3 x Interest Coverage 0.2 x Quarterly #N/A #N/A #N/A #N/A #N/A 0.1 x TTM #N/A #N/A #N/A #N/A #N/A 0.0 x Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 Interest Coverage Rating Qtrly Interest Coverage Rating Quarterly TTM Interest Coverage Rating TTM Interest Coverage Rating N/A
  • 8. investorSCOREcard Cipher Pharmaceuticals Inc (DND-T) Revenue, EBITDA and EPS Rating 3.6 Revenue (in millions) Revenue (in milions) on Rolling TTM $6.00 $5.00 Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 Revenue $ 0.8 $ 0.9 $ 0.5 $ 1.5 $ 3.2 $4.00 Quarterly Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 Basis Quarter Ending $ 0.7 $ 1.1 $ 0.8 $ 0.9 $ 2.2 $3.00 TTM $ 2.4 $ 2.8 $ 3.2 $ 3.5 $ 5.0 $2.00 Growth Percent Rating Stability R² Rating Rev. Growth % TTM 112.5% 5.0 Revenue Stability TTM 87.5% 4.4 $1.00 Rev. Growth % LFY 106.0% 5.0 Revenue Stability Last 2 Yrs 94.0% 4.7 Rev. Growth % 3 Year CAGR Revenue Stability Last 3 Yrs $- Rev. Growth % 5 Year CAGR Revenue Stability Last 5 Yrs Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun Revenue Growth Rating 5.0 Overall Revenue Stability Rating 4.5 01 02 03 04 05 06 07 08 09 10 Revenue Growth and Stability Rating 4.8 EBITDA (in millions) EBITDA (in milions) on Rolling TTM $- ($2.00) Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 ($4.00) EBITDA ($16.5) ($11.6) ($6.7) ($3.3) ($2.0) ($6.00) ($8.00) Quarterly Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 Basis Quarter Ending ($0.6) ($0.3) ($0.5) ($0.3) $ 0.9 ($10.00) TTM ($1.7) ($2.0) ($2.0) ($1.7) ($0.2) ($12.00) ($14.00) Growth Percent Rating Stability R² Rating EBITDA Growth % TTM 87.1% 2.5 EBITDA Stability TTM 44.8% 2.2 ($16.00) EBITDA Growth % LFY 39.0% 2.5 EBITDA Stability Last 2 Yrs 90.0% 4.5 ($18.00) EBITDA Grwth % 3 Yr CAGR 69.6% 2.5 EBITDA Stability Last 3 Yrs 93.3% 4.7 ($20.00) EBITDA Grwth % 5 Yr CAGR 49.4% 2.5 EBITDA Stability Last 5 Yrs 51.7% 2.6 Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun EBITDA Growth Rating 2.5 Overall EBITDA Stablitity Rating 3.5 01 02 03 04 05 06 07 08 09 10 EBITDA Growth and Stability Rating 3.0 Basic Earnings Per Share (EPS*) $- * (excluding acquired in process R&D, restructuring and M&A, special income & charges and discontinued ops) ($0.10) Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 EPS on Rolling TTM ($0.20) EPS ($0.79) ($0.51) ($0.27) ($0.14) ($0.11) ($0.30) Quarterly (TTM) Basis Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 ($0.40) Quarter Ending ($0.03) ($0.02) ($0.02) ($0.02) $ 0.03 ($0.50) TTM ($0.08) ($0.11) ($0.10) ($0.09) ($0.03) ($0.60) Growth Percent Rating Stability R² Rating ($0.70) EPS Growth % TTM 62.5% 2.5 EPS Stability TTM 36.8% 1.8 EPS Growth % LFY 21.4% 1.9 EPS Stability Last 2 Yrs 88.1% 4.4 ($0.80) EPS Grwth % 3 Year CAGR 54.6% 2.5 EPS Stability Last 3 Yrs 91.1% 4.6 ($0.90) EPS Grwth % 5 Year CAGR 42.3% 2.4 EPS Stability Last 5 Yrs 76.7% 3.8 Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun EPS Growth Rating 2.3 Overall EPS Stablitity Rating 3.7 01 02 03 04 05 06 07 08 09 10 EPS Growth and Stability Rating 3.0
  • 9. investorSCOREcard Cipher Pharmaceuticals Inc (DND-T) Return On Capital Rating 0.4 Return On Invested Capital (ROIC) 0% Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 Invested Capital Period Ending $ 22.3 $ 21.5 $ 16.9 $ 14.0 $ 11.3 (10%) Average Invested Capital $ 27.7 $ 21.9 $ 19.2 $ 15.4 $ 12.7 ROIC on Rolling TTM * Net Income ($16.0) ($11.6) ($6.9) ($3.9) ($3.5) (20%) Add Back: After Tax Interest Expense $ - $ - $ - $ - $ - Annual ROIC -57.8% -53.2% -36.1% -25.1% -27.3% (30%) Basis Level Rating 0.0 0.0 0.0 0.2 0.1 Consistency Rating 0.1 (40%) Quarterly (TTM) Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 Invested Capital Period Ending $ 12.8 $ 12.1 $ 11.3 $ 12.3 $ 12.7 (50%) Average Invested Capital $ 13.7 $ 13.3 $ 12.7 $ 12.3 $ 12.2 * Net Income ($2.7) ($3.5) ($3.5) ($3.2) ($1.6) (60%) Add Back: After Tax Interest Expense $ - $ - $ - $ - $ - Quarterly ROIC -19.6% -25.9% -27.3% -25.8% -13.4% Level Rating 0.4 0.2 0.1 0.2 0.7 (70%) Consistency Rating 0.3 Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun 01 02 03 04 05 06 07 08 09 10 Return on Invested Capital (ROIC) Rating 0.3 Return On Assets (ROA) 0% Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 Total Assets Period Ending $ 25.7 $ 22.5 $ 18.7 $ 16.4 $ 14.8 (10%) Average Total Assets $ 32.3 $ 24.1 $ 20.6 $ 17.5 $ 15.6 ROA on Rolling TTM * Net Income ($16.0) ($11.6) ($6.9) ($3.9) ($3.5) Add Back: After Tax Interest Expense $ - $ - $ - $ - $ - (20%) Annual ROA -49.5% -48.2% -33.5% -22.1% -22.2% Basis Level Rating 0.0 0.0 0.1 0.4 0.4 Consistency Rating 0.2 (30%) Quarterly (TTM) Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 (40%) Total Assets Period Ending $ 15.5 $ 15.4 $ 14.8 $ 16.3 $ 16.9 Average Total Assets $ 16.0 $ 15.9 $ 15.4 $ 15.4 $ 15.8 * Net Income ($2.7) ($3.5) ($3.5) ($3.2) ($1.6) (50%) Add Back: After Tax Interest Expense $ - $ - $ - $ - $ - Quarterly ROA -19.6% -25.9% -27.3% -25.8% -13.4% Level Rating 0.5 0.3 0.2 0.3 0.9 (60%) Consistency Rating 0.4 Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun 01 02 03 04 05 06 07 08 09 10 Return on Assets (ROA) Rating 0.5 Return On Common Equity (ROE) 0% Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 Total Equity Period Ending $ 22.3 $ 21.5 $ 15.7 $ 13.0 $ 11.0 (10%) Average Common Equity $ 26.4 $ 21.9 $ 18.6 $ 14.4 $ 12.0 ROE on Rolling TTM * Net Income ($16.0) ($11.6) ($6.9) ($3.9) ($3.5) (20%) Add Back: NA $ - $ - $ - $ - $ - Annual ROE -60.7% -53.2% -37.2% -27.0% -28.8% (30%) Basis Level Rating 0.0 0.0 0.1 0.4 0.3 Consistency Rating 0.2 (40%) Quarterly (TTM) Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 Total Equity Period Ending $ 11.8 $ 11.4 $ 11.0 $ 10.6 $ 11.5 (50%) Average Common Equity $ 12.7 $ 12.4 $ 11.9 $ 11.4 $ 11.2 * Net Income ($2.7) ($3.5) ($3.5) ($3.2) ($1.6) (60%) Add Back: NA - - - - - Quarterly ROE -21.1% -27.8% -29.0% -27.8% -14.6% Level Rating 0.6 0.3 0.3 0.3 0.9 (70%) Consistency Rating 0.5 Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun 01 02 03 04 05 06 07 08 09 10 Return on Common Equity (ROE) Rating 0.5 * Net Income - Excludes Net Income from Discontinued Operations, Income Acquired in Process R&D, Income Restructuring And M&A, and Other Special Income/(Charges)
  • 10. investorSCOREcard Cipher Pharmaceuticals Inc (DND-T) Valuation Rating 2.8 Price to Earnings (P/E) 1.0 x (Lower numbers receive higher rankings) 0.9 x Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 0.8 x * Price $ 4.85 $ 4.40 $ 1.20 $ 0.62 $ 1.15 P/E on Rolling TTM Earnings Per Share (EPS) ($0.79) ($0.51) ($0.27) ($0.14) ($0.11) 0.7 x 0.6 x Annual P/E Basis Annual P/E Rating 0.5 x 0.4 x Quarterly (TTM) Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 * Price $ 0.75 $ 0.46 $ 1.15 $ 1.17 $ 1.25 0.3 x Earnings Per Share (EPS) ($0.08) ($0.11) ($0.10) ($0.09) ($0.03) 0.2 x Quarterly (TTM) P/E 0.1 x Quarterly (TTM) P/E Rating 0.0 x Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun 01 02 03 04 05 06 07 08 09 10 Price to Earnings (P/E) N/A Price to Book (P/Book) 6.0 x (Lower numbers receive higher rankings) Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 5.0 x P/Book on Quarterly * Price $ 4.85 $ 4.40 $ 1.20 $ 0.62 $ 1.15 Book Equity Per Share $ 1.04 $ 0.89 $ 0.65 $ 0.54 $ 0.46 4.0 x Annual P/Book 4.6 x 4.9 x 1.8 x 1.1 x 2.5 x Basis Annual P/Book Rating 0.8 0.6 3.6 4.2 2.9 3.0 x Quarterly Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 2.0 x * Price $ 0.75 $ 0.46 $ 1.15 $ 1.17 $ 1.25 Book Equity Per Share $ 0.49 $ 0.48 $ 0.46 $ 0.44 $ 0.48 1.0 x Quarterly P/Book 1.5 x 1.0 x 2.5 x 2.7 x 2.6 x Quarterly P/Book Rating 3.9 4.3 2.9 2.7 2.8 0.0 x Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun 01 02 03 04 05 06 07 08 09 10 Price to Book (P/Book) 2.8 Enterprise Value to EBITDA (EV/EBITDA) 1.0 x (Lower numbers receive higher rankings) 0.9 x EV/EBITDA on Rolling TTM Annual (Fiscal Year) Dec-05 Dec-06 Dec-07 Dec-08 Dec-09 0.8 x * Enterprise Value $ 103.48 $ 105.76 $ 30.06 $ 15.91 $ 27.99 EBITDA ($16.47) ($11.57) ($6.74) ($3.33) ($2.03) 0.7 x 0.6 x Annual EV/EBITDA Basis Annual EV/EBITDA Rating 0.5 x 0.4 x Quarterly (TTM) Jun-09 Sep-09 Dec-09 Mar-10 Jun-10 * Enterprise Value $ 19.01 $ 11.69 $ 27.99 $ 29.85 $ 30.10 0.3 x EBITDA ($1.68) ($2.03) ($2.03) ($1.74) ($0.22) 0.2 x Quarterly (TTM) EV/EBITDA 0.1 x Quarterly (TTM) EV/EBITDA Rating 0.0 x Jun Jun Jun Jun Jun Jun Jun Jun Jun Jun 01 02 03 04 05 06 07 08 09 10 Enterprise Value to EBITDA (EV/EBITDA) N/A * Price - Delayed 60 days to reflect the fact that financial statements are public approximately 60 days after the last day of the reporting period. For the last period the most recent price is used.
  • 11. investorSCOREcard Disclosure and Disclaimer The issuer (“Issuer”) covered under this investor scorecard (“Investor Scorecard”) has paid a fee or has been charged a fee for the production and distribution of this Investor Scorecard. The fee paid or charged for the production and distribution of this Investor Scorecard was not subject to the rankings or information provided herein, nor was any securities of the Issuer accepted as payment for such fee. FSA Financial Science & Art Ltd. (“FSA”), The Equicom Group Inc. (“Equicom”) and their respective employees and directors may have had or from time to time acquire, hold or sell an interest in the listed securities of the Issuer. Unless specified otherwise, all forward looking statements in this Investor Scorecard have been approved by the Issuer, and the Issuer has advised FSA and Equicom, without independent verification by FSA or Equicom that a reasonable basis exists for such forward looking statements. 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