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Bank of America
  Healthcare
  Conference



 May 17, 2006
Jeff Campbell

Executive Vice President
 Chief Financial Officer




                           2
Safe Harbor Clause
Some of the information in this presentation may constitute
forward-looking statements that are subject to various
uncertainties. These uncertainties could cause actual results
to differ materially from those projected or implied. The risk
factors associated with those uncertainties are described in
the Company’s reports and exhibits filed with the Securities
and Exchange Commission. Financial information is
presented here in summary form. Full details are provided in
the Company’s most recent 10-Q report. All of this information
is available at www.mckesson.com. The Company assumes
no obligation to update or revise any such statements,
whether as a result of new information or otherwise.
                                                          3
McKesson Facts
                                     FY06 REVENUES
                                                           Medical-Surgical
                                                           $3.1 B
$88 billion in revenues in FY06    Pharma
FY06 EPS $2.44 (excluding          Solutions
                                                             Provider
                                   $83.4 B
Securities Litigation charge and                             Technologies
                                                             $1.5 B
Discontinued Ops)
Over 27,000 employees              FY06 OPERATING PROFIT
304 million shares outstanding                             Medical-Surgical
                                                           $70 M
$15 billion market cap             Pharma
Founded 1833, headquartered        Solutions
                                                              Provider
                                   $1,211 M
                                                              Technologies
in San Francisco                                              $143 M



      144% Return to Shareholders since April 1, 2000
                                                                      4
Delivering Value from the
Center of Healthcare


                                            Solutions for
                                          medication safety
  Pharmaceutical & medical-
surgical distribution to all sites
                                                                          Information solutions
                                                                          for hospitals, payors,
                                                                             home care, and
                                                                               physicians

                              Inpatient automation
                                                           Specialty
Retail pharmacy                                         pharmaceuticals
  automation


                                                                                 Disease
                    Pharmacy outsourcing
                                                                               management
                                                 Pharmaceutical
                       and consulting
                                                  repackaging
                                                                                            5
Market Leading Positions
in Healthcare Services
        McKesson                McKesson                  McKesson
      Pharmaceutical          Medical-
                              Medical-Surgical      Provider Technologies

   #1 in U.S., Canada, and    #1 in primary care    63% of health systems
            Mexico
                                                    51% of hospitals with
                              #1 in extended care
    Large Rx repackaging                                200+ beds
                                 Private label
  Leading generics provider                          Leader in clinical,
                               product offerings       revenue cycle,
  Specialty distribution &
                                                        and resource
                               Rapid growth in
    patient services for
                                                    management solutions
                               physician office
       manufacturers
                               pharmaceuticals       More “Best in KLAS”
 #1 in medical management       and equipment         products than any
  software and services for                             other vendor
           payors
                                                    #1 in robotic hospital
 #1 in disease management                           pharmacy dispensing
    for Medicaid agencies
                                                    #1 in bedside scanning




                                                                             6
Leader in Growing Areas
                                                                                                            Canadian Pharmaceutical
                                                                                                            $12 B US
                                                                                                            5-7% projected growth (1)


                                                                                                                 U.S. Medical-Surgical
                                                                                                                 $80 B
                  U.S. Pharmaceutical
                                                                                                                 6-8% projected growth   (2)
                  $234 B
                  5-8% projected growth                   (1)

                                                                                                                  HIT – Hospital, Alternate Site
                                                                                                                  and Automation
                                                                                                                  $28 B
                                                                                                                  6-7% projected growth (3)


                                                                                                          Payor – Outsourced and
                                                                                                          Software
                                                                                                          $8 B
(1)   IMS
                                                                                                          20-25% projected growth (4)
(2)   Medical Devices & Supplies M arket Update
(3)   Datamonitor, 2005
(4)   Includes medical management s oftware/c ontent, diseas e management, coding, compliance ser vices



                      Well positioned in all growing healthcare areas
                                                                                                                                                   7
Long-term Relationships
with Market Leaders
          Vanderbilt University Medical Center




                                                 8
McKesson’s Strategy
  To bring together clinical knowledge, process
    expertise, technology, and the resources of
     a Fortune 16 company to fundamentally
      change the cost and quality of healthcare.

 Create long-term                          Introduce
relationships based   Sell McKesson’s   innovations that
on custom solutions    comprehensive    address emerging
    that deliver           offering        healthcare
   ROI & quality                           challenges



                                                      9
Six Years of Strong Growth
$ Billions
 Warehouse Sales
 Direct Revenues                                        s)                $88.1
                                                   sale
                                             ota l
                                R         (t                    $80.1
                             CAG
                          6%
                      1                                 $69.2

                                  $57.1
                          $50.0
              $42.0
   $36.7




       0          1       2           3                    4         5        6
    Y0         Y0      Y0          Y0                   Y0        Y0       Y0
  F          F        F           F                    F        F        F

                                                                                  10
Diluted EPS
(continuing operations)*


                                                   A GR
                                                 C
                                       25 %
                                                                                                       $2.44

                                                                                   $2.18     $2.18
                                                                  $1.89
                                               $1.43

        $0.65

                          ($0.15)
      00




                         01




                                            02




                                                               03




                                                                                   04




                                                                                             05




                                                                                                       06
    FY




                       FY




                                          FY




                                                             FY




                                                                                 FY




                                                                                           FY




                                                                                                     FY
                                                                                                               11
Note: EPS from continuing operations, excluding securities litigation charges.
Diluted EPS Reconciliation
($ and shares in millions, except EPS)
                                                                               FY04                   FY05                 FY06
Net income (loss), continuing ops
                                                                          $        643          $       (160)         $        737
- as reported

Exclude:
                                                                                    -                 1,200                      45
  Securities Litigation charges, net
                                                                                    -                  (390)                    (15)
  Estimated income tax benefit
                                                                                    -                   810                      30
Net income, continuing ops, excluding
                                                                          $        643          $        650          $        767
 Securities Litigation charges


Diluted earnings per common
share, continuing ops, excluding Securities
                                                                          $        2.18         $        2.18         $         2.44
                            (1) (2)
Litigation charges

Shares on which diluted
earnings per common
                                                                                   299                   301                   316
                           (2)
share were based

(1) Certain computations m ay r eflect rounding adjustments.
(2) For the year s ended Mar ch 31, 2006, 2005 and 2004, inter est exp ense, net of r elat ed incom e taxes, of $1 m illion, $6 million and $6 million has been add ed to net incom e,
excluding the Secur ities Litigation charges, for purposes of calculating diluted earning s per sh are. This calculation also includ es the impact of dilutive secur ities (stock options,
convertible junior subordinat ed debentures and restricted stock).

                                                                                                                                                                                   13
Diluted EPS Reconciliation
($ and shares in millions, except EPS)
                                                                                                   Q4                                              Full Year
                                                                                       FY05                FY06                                  FY05       FY06
Net income, (loss) continuing ops
- as reported                                                                    $       258          $        220                         $       (160)        $        737

Exclude:
 Securities Litigation charges (credits), net                                                  -                  (8)                            1,200                     45
 Estimated income tax benefit                                                                  -                   3                              (390)                   (15)
                                                                                               -                  (5)                               810                    30
Net income, continuing ops,
                                                                                 $       258          $        215                         $        650         $        767
  excluding Securities Litigation charges

Diluted earnings per common
share, continuing ops,
                                                       (1) (2)
                                                                                 $        0.85        $        0.68                        $        2.18        $         2.44
excluding Secuities Litigation charges

Shares on which diluted
earnings per common
share were based (2)                                                                     305                   314                                  301                  316

(1) Certain computations m ay r eflect rounding adjustments.
(2) For the year s ended Mar ch 31, 2006, 2005 and 2004, inter est exp ense, net of r elat ed incom e taxes, of $1 m illion, $6 million and $6 million has been add ed to net incom e,
excluding the Secur ities Litigation charges, for purposes of calculating diluted earning s per sh are. This calculation also includ es the impact of dilutive secur ities (stock options,
convertible junior subordinat ed debentures and restricted stock).

                                                                                                                                                                                   14

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Banc of America Securities 2006 Health Care Conference Presentation

  • 1. Bank of America Healthcare Conference May 17, 2006
  • 2. Jeff Campbell Executive Vice President Chief Financial Officer 2
  • 3. Safe Harbor Clause Some of the information in this presentation may constitute forward-looking statements that are subject to various uncertainties. These uncertainties could cause actual results to differ materially from those projected or implied. The risk factors associated with those uncertainties are described in the Company’s reports and exhibits filed with the Securities and Exchange Commission. Financial information is presented here in summary form. Full details are provided in the Company’s most recent 10-Q report. All of this information is available at www.mckesson.com. The Company assumes no obligation to update or revise any such statements, whether as a result of new information or otherwise. 3
  • 4. McKesson Facts FY06 REVENUES Medical-Surgical $3.1 B $88 billion in revenues in FY06 Pharma FY06 EPS $2.44 (excluding Solutions Provider $83.4 B Securities Litigation charge and Technologies $1.5 B Discontinued Ops) Over 27,000 employees FY06 OPERATING PROFIT 304 million shares outstanding Medical-Surgical $70 M $15 billion market cap Pharma Founded 1833, headquartered Solutions Provider $1,211 M Technologies in San Francisco $143 M 144% Return to Shareholders since April 1, 2000 4
  • 5. Delivering Value from the Center of Healthcare Solutions for medication safety Pharmaceutical & medical- surgical distribution to all sites Information solutions for hospitals, payors, home care, and physicians Inpatient automation Specialty Retail pharmacy pharmaceuticals automation Disease Pharmacy outsourcing management Pharmaceutical and consulting repackaging 5
  • 6. Market Leading Positions in Healthcare Services McKesson McKesson McKesson Pharmaceutical Medical- Medical-Surgical Provider Technologies #1 in U.S., Canada, and #1 in primary care 63% of health systems Mexico 51% of hospitals with #1 in extended care Large Rx repackaging 200+ beds Private label Leading generics provider Leader in clinical, product offerings revenue cycle, Specialty distribution & and resource Rapid growth in patient services for management solutions physician office manufacturers pharmaceuticals More “Best in KLAS” #1 in medical management and equipment products than any software and services for other vendor payors #1 in robotic hospital #1 in disease management pharmacy dispensing for Medicaid agencies #1 in bedside scanning 6
  • 7. Leader in Growing Areas Canadian Pharmaceutical $12 B US 5-7% projected growth (1) U.S. Medical-Surgical $80 B U.S. Pharmaceutical 6-8% projected growth (2) $234 B 5-8% projected growth (1) HIT – Hospital, Alternate Site and Automation $28 B 6-7% projected growth (3) Payor – Outsourced and Software $8 B (1) IMS 20-25% projected growth (4) (2) Medical Devices & Supplies M arket Update (3) Datamonitor, 2005 (4) Includes medical management s oftware/c ontent, diseas e management, coding, compliance ser vices Well positioned in all growing healthcare areas 7
  • 8. Long-term Relationships with Market Leaders Vanderbilt University Medical Center 8
  • 9. McKesson’s Strategy To bring together clinical knowledge, process expertise, technology, and the resources of a Fortune 16 company to fundamentally change the cost and quality of healthcare. Create long-term Introduce relationships based Sell McKesson’s innovations that on custom solutions comprehensive address emerging that deliver offering healthcare ROI & quality challenges 9
  • 10. Six Years of Strong Growth $ Billions Warehouse Sales Direct Revenues s) $88.1 sale ota l R (t $80.1 CAG 6% 1 $69.2 $57.1 $50.0 $42.0 $36.7 0 1 2 3 4 5 6 Y0 Y0 Y0 Y0 Y0 Y0 Y0 F F F F F F F 10
  • 11. Diluted EPS (continuing operations)* A GR C 25 % $2.44 $2.18 $2.18 $1.89 $1.43 $0.65 ($0.15) 00 01 02 03 04 05 06 FY FY FY FY FY FY FY 11 Note: EPS from continuing operations, excluding securities litigation charges.
  • 12.
  • 13. Diluted EPS Reconciliation ($ and shares in millions, except EPS) FY04 FY05 FY06 Net income (loss), continuing ops $ 643 $ (160) $ 737 - as reported Exclude: - 1,200 45 Securities Litigation charges, net - (390) (15) Estimated income tax benefit - 810 30 Net income, continuing ops, excluding $ 643 $ 650 $ 767 Securities Litigation charges Diluted earnings per common share, continuing ops, excluding Securities $ 2.18 $ 2.18 $ 2.44 (1) (2) Litigation charges Shares on which diluted earnings per common 299 301 316 (2) share were based (1) Certain computations m ay r eflect rounding adjustments. (2) For the year s ended Mar ch 31, 2006, 2005 and 2004, inter est exp ense, net of r elat ed incom e taxes, of $1 m illion, $6 million and $6 million has been add ed to net incom e, excluding the Secur ities Litigation charges, for purposes of calculating diluted earning s per sh are. This calculation also includ es the impact of dilutive secur ities (stock options, convertible junior subordinat ed debentures and restricted stock). 13
  • 14. Diluted EPS Reconciliation ($ and shares in millions, except EPS) Q4 Full Year FY05 FY06 FY05 FY06 Net income, (loss) continuing ops - as reported $ 258 $ 220 $ (160) $ 737 Exclude: Securities Litigation charges (credits), net - (8) 1,200 45 Estimated income tax benefit - 3 (390) (15) - (5) 810 30 Net income, continuing ops, $ 258 $ 215 $ 650 $ 767 excluding Securities Litigation charges Diluted earnings per common share, continuing ops, (1) (2) $ 0.85 $ 0.68 $ 2.18 $ 2.44 excluding Secuities Litigation charges Shares on which diluted earnings per common share were based (2) 305 314 301 316 (1) Certain computations m ay r eflect rounding adjustments. (2) For the year s ended Mar ch 31, 2006, 2005 and 2004, inter est exp ense, net of r elat ed incom e taxes, of $1 m illion, $6 million and $6 million has been add ed to net incom e, excluding the Secur ities Litigation charges, for purposes of calculating diluted earning s per sh are. This calculation also includ es the impact of dilutive secur ities (stock options, convertible junior subordinat ed debentures and restricted stock). 14