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Chapter 9 
Cellular Respiration
Chemical Energy 
• Living things get energy from the food they 
consume 
• Calorie – the amount of energy needed to 
raise the temperature of 1 gram of water 1 
°C 
• 1 gram of glucose when burned in the 
presence of oxygen releases 3811 C
Cellular respiration 
• Process that releases energy by breaking 
down glucose and other food molecules in 
the presence of oxygen (aerobic) 
• 6O2 + C6H12O6 → 6CO2 + 6H2O + energy 
• Oxygen + glucose → carbon dioxide + water + energy 
• Three main stages: 
– Glycolysis 
– Krebs Cycle 
– Electron transport
Glycolysis 
• The process in which one molecule of 
glucose is broken in half producing two 
molecules of pyruvic acid; a 3-carbon 
compound 
• 2 ATP molecules are used to get the 
reaction going and will produce 4 ATP 
molecules when the process is complete
Cont. 
• NAD+ (electron carrier) accepts 4 high 
energy electrons and becomes NADH 
• This process can produce thousands of 
ATP molecules in a few milliseconds 
• Does not require oxygen (anaerobic) 
• Energy is used up quickly
Fermentation 
• Production of ATP in the absence of 
oxygen (anaerobic) 
• Two types: Alcoholic fermentation and 
Lactic acid fermentation 
• Alcohol fermentation: NADH is converted 
back to NAD+ by passing high energy 
electrons back to pyruvic acid 
• Pyruvic acid + NADH → alcohol + CO2 and NAD+
Cont. 
• Lactic fermentation: NADH is converted 
back to NAD+ by passing high energy 
electrons back to pyruvic acid and 
producing lactic acid 
• Lactic acid is produced in muscle when 
the body cannot supply enough oxygen 
• Pyruvic acid + NADH → lactic acid + NAD+
Krebs Cycle 
• End of glycolysis, 90% of chemical energy 
in glucose is still unused, cell will use 
oxygen to extract the remaining energy 
• Krebs cycle begins when pyruvic acid 
produced by glycolysis enters the 
mitochondrion 
• Pyruvic acid is used to make carbon 
dioxide, ATP, NADH, and FADH2
Electron Transport Chain 
• Uses the high energy electrons from the 
Krebs cycle to convert ADP to ATP 
• In eukaryotes: inner membrane of the 
mitochondrion 
• In prokaryotes: in the cell membrane 
• H+ builds up in the intermembrane space 
making it positively charged…other side, 
is now negatively charged
• As H+ escape through membrane, the 
mitochondria contain proteins (ATP 
synthase) which rotates, the enzyme 
grabs the low energy ADP and attaches a 
phosphate forming high energy ATP 
• Process is repeated over and over
Energy for the body 
• Quick – gylcolysis or fermentation 
• Long term- cellular respiration
Summary 
• Cellular respiration has 3 stages: 
– Glycolysis 
– Krebs cycle 
• Electron transport chain

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Chapter 9

  • 1. Chapter 9 Cellular Respiration
  • 2. Chemical Energy • Living things get energy from the food they consume • Calorie – the amount of energy needed to raise the temperature of 1 gram of water 1 °C • 1 gram of glucose when burned in the presence of oxygen releases 3811 C
  • 3. Cellular respiration • Process that releases energy by breaking down glucose and other food molecules in the presence of oxygen (aerobic) • 6O2 + C6H12O6 → 6CO2 + 6H2O + energy • Oxygen + glucose → carbon dioxide + water + energy • Three main stages: – Glycolysis – Krebs Cycle – Electron transport
  • 4. Glycolysis • The process in which one molecule of glucose is broken in half producing two molecules of pyruvic acid; a 3-carbon compound • 2 ATP molecules are used to get the reaction going and will produce 4 ATP molecules when the process is complete
  • 5. Cont. • NAD+ (electron carrier) accepts 4 high energy electrons and becomes NADH • This process can produce thousands of ATP molecules in a few milliseconds • Does not require oxygen (anaerobic) • Energy is used up quickly
  • 6.
  • 7. Fermentation • Production of ATP in the absence of oxygen (anaerobic) • Two types: Alcoholic fermentation and Lactic acid fermentation • Alcohol fermentation: NADH is converted back to NAD+ by passing high energy electrons back to pyruvic acid • Pyruvic acid + NADH → alcohol + CO2 and NAD+
  • 8. Cont. • Lactic fermentation: NADH is converted back to NAD+ by passing high energy electrons back to pyruvic acid and producing lactic acid • Lactic acid is produced in muscle when the body cannot supply enough oxygen • Pyruvic acid + NADH → lactic acid + NAD+
  • 9. Krebs Cycle • End of glycolysis, 90% of chemical energy in glucose is still unused, cell will use oxygen to extract the remaining energy • Krebs cycle begins when pyruvic acid produced by glycolysis enters the mitochondrion • Pyruvic acid is used to make carbon dioxide, ATP, NADH, and FADH2
  • 10. Electron Transport Chain • Uses the high energy electrons from the Krebs cycle to convert ADP to ATP • In eukaryotes: inner membrane of the mitochondrion • In prokaryotes: in the cell membrane • H+ builds up in the intermembrane space making it positively charged…other side, is now negatively charged
  • 11. • As H+ escape through membrane, the mitochondria contain proteins (ATP synthase) which rotates, the enzyme grabs the low energy ADP and attaches a phosphate forming high energy ATP • Process is repeated over and over
  • 12. Energy for the body • Quick – gylcolysis or fermentation • Long term- cellular respiration
  • 13. Summary • Cellular respiration has 3 stages: – Glycolysis – Krebs cycle • Electron transport chain