Exam 4 review: this is chapter 8

1. Exam 4 review: Ch.8
GO TO SLIDESHARE POWERED BY LINKEDIN AND SEARCH
“DANIELEISENSTEIN1”

2. Alkene fun facts
 C=C bond
 Sp2 hybridized = trigonal planar
 Pi and sigma bond
 Don’t conform

3. Alkene Stability

4. Practice

5. Leaving Group Ability

6. Nucleophilicity (correction)
 Increases with negative charge
 Increases as steric hinderance decreases
 The following slide shows the periodic trend

8. Beta carbons
 Beta carbons are around the functional group
 Finding beta carbons is the first step
 Find Beta carbons and draw all Elimination products
 This is 8.1 in solution manual

9. Its all about that base!
 Basicity increases as it gets negative
 Basicity is not as dependent on steric hinderance as
nucleophiles
 A sterically hindered base is called a nonnucleophilic base
 B: is the symbol for a base

10. Trend for basicity

11. Elimination reaction
 Forms alkene
 We need a strong base
 We need a Leaving Group
 As number of R groups increase, rate of
reaction increases
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12. E2 reaction
 Rate= k[substrate][base]
 Bimolecular
 Concerted
 Strong base
 Mechanism
 Requires anti periplanar geometry
 Trans-diaxial on a ring
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CC BY-SA-NC

13. Practice

14. practice

15. practice

16. Major vs. Minor products
 We want the most stable product
 Follows Zaitsev’s rule
 The less stable product can be favored
 Hoffmann product
 Due to steric effects
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17. Practice (8.12)
What alkenes are
formed?
Follow zaittsev rule

18. E1 reaction
 Weak base
 Unimolecular
 Involves carbocation intermediate
 Two-step reaction
 Rate= k[substrate]
 Mechanism
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19. E1 vs. E2

20. E1 vs. E2 vs. Sn1 vs. Sn2
 BIG DADDY FLOW CHART
 This is not mine
 This is the work of clutchprep
 If you are having trouble in this
course or in organic chemistry 2, I
highly recommend them
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21. Practice (8.16)

22. Questions I like
 8.1, 8.3, 8.5, 8.6, 8.7, 8.8, 8.9, 8.10, 8.11, 8.12, 8.13, 8.14, 8.15, 8.18, 8.19
 You know what, I Iike all of them