The Transforming Alphabetacy - Chapter 2darkangel985
This is the second chapter of my Transformers themed Alphabetacy in the Sims 2. I suggest reading the first chapter if you haven't already or visit the topic at boolprop.com. I have a heirpoll there, but also accept votes on here.
The newly-graduated Gen 2 kids settle into their respective lives. We have our first real wedding and our first death, and the first Gen 3 kids make an appearance.
The Transforming Alphabetacy - Chapter 2darkangel985
This is the second chapter of my Transformers themed Alphabetacy in the Sims 2. I suggest reading the first chapter if you haven't already or visit the topic at boolprop.com. I have a heirpoll there, but also accept votes on here.
The newly-graduated Gen 2 kids settle into their respective lives. We have our first real wedding and our first death, and the first Gen 3 kids make an appearance.
The Hanok City Masterplan is the culmination of the work done by students in the 2012 Physical Planning and Urban Design Capstone as part of their master's requirements at the University of Michigan.
I Love Lucy Day 1. Lucy Munster, Generation 4 Sparess, allows 7 men from seven different legacies to compete for her heart. Who will be victorious? Find out.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
Chapter 3.3: Tying Off the Loose Ends
1. Hi, welcome back to the Absolutely Crazy Matriarchy! Who is this, you ask? This is my simself, the imaginatively-named Fire Simself. o_O She's going to be doing the introductions from now on, plus a few cameos. "Hi everyone! Last time in the Absolutely Crazy Matriarchy, our heir Rebakah Chandler came home from College. Her older brother and spare Daniel moved in with his girlfriend, Shenene Gast."
3. They wasted little time in getting married. They had decided on a small, intimate ceremony without all the drama of family and such. Now, back to the REAL story.
4. "Rebakah! You're home!" "I didn't mean to get you and mum out of bed, Grandmama." "Oh, I don't mind. I get to see my little Beka again!"
6. I've remodeled the second floor so Beka will have somewhere more comfortable to sleep than in her teenage bedroom. Plus, I've added a nursery for her future kiddies.
7. And she's been home all of three hours, and she manages to set the kitchen on fire. With full cooking skill. Really, Beka, you should know better.
8. "Nothing in the Intelligence career for me." Okay then, you can stay unemployed for a while. I have plans for you anways. "Plans?" Yep. Go out to a community lot and get some clothes.
10. "So what am I doing here? I have my new clothes, can't I go home?" Nope. You have to find a witch. "What?" You thought I'd forgotten?
12. And Rebakah greets her and immediately strikes up a coversation. "So what's it like being a witch?" "Difficult but rewarding. Are you considering on walking the path, dear? "Well, I wasn't, but then Fire my legacy creator said I had to. So, yeah." "Oh dear. A Legacy. I see." Why the negative attitude? Yeesh.
13. When Beka got home I had Holly add her to the Legacy Wall. Since this shot was taken in medium quality (as has been most of the legacy so far, oops) it's a little indistinct. But nice.
14. Oh no. Beka, what are you eating? "Not sure. I found it in the fridge and it tastes good." It's cheesecake, isn't it? Damn. "What's wrong with cheesecake?" Cheesecake causes twins. "Oh crud."
15. "So, I guess I have to start continuing the family line now." Not just yet. I want you in your career first. That means Intelligence, not anything else. "Right."
16. Nice little familt shot here. They all share a certain... resemblance. Gotta be the brown hair. Stupidly I chose a dominant hair type for my founder. Oops.
17. "Ah, my dear, good to see you. Have you decided to become a witch yet?" "Yes, I have." "Excellent!" *casts spell*
19. "Hey, I feel... magical. But these clothes are ick." You can go get yours back if you want. "Okeydokey."
20. "My first spell!" All Good witches cast Beautificus Locus when they're transformed. Just in case you didn't know.
21. "So much more to learn! So many spells, so little time..." A lot of these spells will come in handy - particularly the conjured servant. Cheaper than a maid. But spookier.
22. "I have chicken pox!" Sims don't get chicken pox. Plus, chicken pox usually doesn't show as little gold sparkles. The sparkles are just a symptom of having high virtue as a witch. "Okay, I think I can live with the sparkles." Wait till she gets the glowy blue aura.
23. "Damion! So good to see you!" "My girlfriend has sparkly skin. New moisturiser?" Um, no. She's a witch now. "Oh, snap! That was unexpected!" "Damion, that was not an 'oh, snap' moment." "Was for me."
24. Damion doesn't seem to mind Beka's new look. "Damn right! I get a sexy older lady! Reow!" "Mmmmph!" Sims are very strange creatures.
25. I love how witches just whip out their wands for no reason. Like the hobby mannerisms. "Hmm, who will I spell next?"
26. It's Susan's birthday! On a side note, Beka has made full virtue. "I glow now!" Make a wish, Susan. "I wish... for grandchildren by the dozen!" Um. No. Not happening. Sorry. Maximum of four. (My own rules.)
28. And in that burst of confetti is our beloved, elder-ified Susan. She has aged well, exceot for the tacky elder clothes. To the shopping center, Susan! "I want something purple." Why am I not surprised?
29. Ahh, that's better. "So, I get to be a grandma soon?" Yeah, if Beka gets her career sorted. Stupid career track hasn't shown up yet.
30. Beka, it's been a week. Still no Intelligence career. Care to settle for something else? "Nope. A LTW is a LTW." Dang, she's right.
31. These things creep me out. They just float, but with walky movements. Plus, if you listen, they have guy voices. Even though the non-being-thing clearly has invisible girly-bumps. Creepy.
32. To alleviate the family's despair at Beka's inability to get a job, I have adopted for them an adorable little kitten called Popcorn. "Aww, she's so cute!"
33. And old. She grew up an hour after she got to the house. Weird, I pay for a kitten and get a cat. Popcorn needs a makeover to be more Popcorn-ish, I think.
34. Ahh, that's better. Wonder if this is one of those legacies where the pets talk...? *silence* Apparently not.
35. It's been a week. Still no Intelligence career. This stinks. "Ya reckon?"
36. "Hey, I have a castle!" Dream on, Rebakah. Mind you, I wish you were right. Having Sims in the Palace of Neverending Light would be way awesomer than stupid Legacy lots.
37. "Fire? Can I have a word?" Sure, Holly. "I'm getting too old for raising children. I don't think I could handle any great grandchildren." You won't have to, Holly. "Why not?" Oh, Holly. Your lifetimer is running out. You only have a few hours left.
38. "I love you, Pao. You'll find someone else, someday. Someone who you can grow old with, someone you can marry and have boatloads of kids with." "I'll never forget you, my Holly."
39. "It's up to you to keep things together now, Susan. Be well." "I love you, mum. Wait for us." "I will, don't worry."
40. "Beka... the pressure is on you, now. Be yourself, always." "I will, grandmama. I'll miss you." "We'll meet again someday, dear." Um, Holly? Your appointment's here.
41. Miss Holly Chandler, aged 81? "That's me." Your time has come. You must come with me now. "I know."
42. "Grandmama!" "Be strong, Beka. Look after Pao for me." Come along, Miss Holly Chandler. "Very well." I think a musical tribute is in order for our founder.
43. Another turning point A fork stuck in the road Time grabs you by the wrist Directs you where to go
44. So make the best of this test And don't ask why It's not a question But a lesson learned in time
46. So take the photographs And the still frames in your mind Hang it on a shelf In good health and good time
47. Tattoos of memories And dead skin on trial For what it's worth It was worth all the while
48. It's something unprediactable But in the end it's right I hope you had the time of your life Greenday - Time of Your Life
49. Holly Chandler Age: 81 Children: Susan Chandler Grandchildren: Rebakah and Daniel Chandler LTW: Top of Medical Career (achieved) Goodbye, Holly.
50. "Oh, mum! Why did you have to leave me?" Susan, it was her time. Now it's up to you to be Matriarch of the Matriarchy.
51. "I miss grandmama. She'll never see her great-grandchildren." I beg to differ. I get the feeling that her ghost will make an appearance at some stage. Gulp.
52. Still no Intelligence job. I've given up and made Beka get a Paranormal job in the interim - at least she'll get the Resurrect-O-Nomitron. "Can I use it on Grandmama?" No. That phone is for emergency use only - like if the heir gets cowplanted or something. "Fair enough."
53. I really love the Thrones of Light. They come in really useful after a long day of reagent making... or during a pregnancy, hint hint. "Not until I get my LTW career, remember?" Which will happen soon. I hope.
54. Ah, Holly! You're back with us! "Indeed, but I feel less substantial than usual." Well, you DID die yesterday evening. "State the obvious day, is it? Ah, I see you have retained my bed." No use having an irritable ghost around.
55. "Fire! Fire! You'll never guess!" You got into the Intelligence career? "Yeah. How'd you guess?" Little birdy. Now, go get some promotions and then we can start the next generation!
56. "This outfit makes me look like a lawyer." You're a spy. You need to look inconspicuous. "I want to head SCIA now." Give it time.
57. And look who's come to visit. Daniel, our favourite spare. Hiya, Daniel! "..." Daniel? "Hi there, mum!" Oh. He can't hear me. How odd.
58. "I just wanted to tell you how awesome your graduation party was. And also Daniel can't hear Fire any more." "That's weird. Wonder why?" "I guess he's no longer part of the main legacy. He doesn't need to hear her." Notice the cheesecake Beka has again. I really want girl twins so I can have an heir poll. Beka has eaten nothing but cheesecake since she got home.
60. "Ah. Apello Simae. Nice thinking, Fire." Quicker than by phone, yes? "Yeah. Plus, it's sparkly!" Legacy Sims are worse than magpies.
61. I think I'll give the two of you some privacy. "That might... mmmph... be a good idea." "Mmmmh..." *runs away*
62. A lullaby! On the first try! That almost never happens to me, that's weird. Oh well. Fingers crossed for twins.
63. "Ugh." Morning sickness, dear Beka? "Indeed. All that cheesecake... looks gross now." That's it for chapter 3.3. Next time in the Absolutely Crazy Matriarchy, a birth! Or perhaps births!
64. "Mum, I think I'm pregnant." "That's fantastic! I can retire now!" Says who? "Says me. Grandkids, here I come!"