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Theme I History Of Microbiology
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Theme I History Of Microbiology
THEME I HISTORY OF MICROBIOLOGY
DEFINITIONS
Microbiology is the science that studies the biology of microorganisms or microbes.
Microorganisms are beings:
· Small size, which can not be observed with the naked eye, it takes a microscope.
· Do not have tissue differentiation, are acellular, one celled, and / or cenocíticos (multicore).
Naturally occurring in mixed populations of cells, where each cell performs its vital functions independently. If we get a pure or axenic culture must apply a methodology of Microbiology for selecting one type of microorganisms.
Microorganisms are therefore those acellular biological entities, unicellular, multicellular and / or cenocíticos, devoid of tissue organization, for its small size, beyond human eye and for study, the methodology of pure culture is required. (examination).
HISTORICAL DEVELOPMENT
Although known recently, profits of microorganisms have been used for thousands of years (bread, wine) ago, suffering their infections, and using prophylactic measures against them (quarantine, sacrifices, etc.)
In the seventeenth century, Antoine van Leeuwenhoek was the first scientist who observed microorganisms. He was a Dutch optician who built the first quality lenses (x 300). He noted the structure of seeds, red blood cells, sperm, but its maximum discovery was animalcules; yeasts, algae, protozoa and some bacterial large.
It took a long time until Microbiology as science develops. This happens at the end of the nineteenth
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Theme I History Of Microbiology
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You get an original and high-quality paper based on extensive research. The completed work will be correctly formatted, referenced and tailored to your level of study.
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We value your privacy. We do not disclose your personal information to any third party without your consent. Your payment data is also safely handled as you process the payment through a secured and verified payment processor.
✅ Originality
Every single order we deliver is written from scratch according to your instructions. We have zero tolerance for plagiarism, so all completed papers are unique and checked for plagiarism using a leading plagiarism detector.
✅ On-time delivery
We strive to deliver quality custom written papers before the deadline. That's why you don't have to worry about missing the deadline for submitting your assignment.
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From answering simple questions to solving any possible issues, we're always here to help you in chat and on the phone. We've got you covered at any time, day or night.
Theme I History Of Microbiology
THEME I HISTORY OF MICROBIOLOGY
DEFINITIONS
Microbiology is the science that studies the biology of microorganisms or microbes.
Microorganisms are beings:
· Small size, which can not be observed with the naked eye, it takes a microscope.
· Do not have tissue differentiation, are acellular, one celled, and / or cenocíticos (multicore).
Naturally occurring in mixed populations of cells, where each cell performs its vital functions independently. If we get a pure or axenic culture must apply a methodology of Microbiology for selecting one type of microorganisms.
Microorganisms are therefore those acellular biological entities, unicellular, multicellular and / or cenocíticos, devoid of tissue organization, for its small size, beyond human eye and for study, the methodology of pure culture is required. (examination).
HISTORICAL DEVELOPMENT
Although known recently, profits of microorganisms have been used for thousands of years (bread, wine) ago, suffering their infections, and using prophylactic measures against them (quarantine, sacrifices, etc.)
In the seventeenth century, Antoine van Leeuwenhoek was the first scientist who observed microorganisms. He was a Dutch optician who built the first quality lenses (x 300). He noted the structure of seeds, red blood cells, sperm, but its maximum discovery was animalcules; yeasts, algae, protozoa and some bacterial large.
It took a long time until Microbiology as science develops. This happens at the end of the nineteenth
Get more content on HelpWriting.net
Biology cell theory-and-and spontaneuous generation
Biology cell theory-and-and spontaneous generation
Introduction of Microbiology (2).pdf
Branches of microbiology
history of microbiology
explain the account on bacteria
UNIT 1 MICROBIOLOGY-Introduction to Microbiology.pptx
introduction to microbiology
history of microbiology
Koch's Postulates
scopes of microbiology
importance of microbiology
branches of microbiology
medical microbiology
types of microorganisms
bacteriology
virology
parasitology
mycology
immunology
brief introduction about microscope & its types
Introduction to microbiology
A brief introductory overview of microbiology subject matter and what it includes. This presentation and the following was teaching undertaken for Allied Health Sciences BSc as part of my postgraduate degree.
A. The development of the has allowed us to study cells and their pro.pdf
A. The development of the has allowed us to study cells and their processes 1. T a. Resolution is
the ability ofamicroscope to show two objects as separate Magnification is how much larger an
object appears compared to its actual size a Light microscopes are the kind we use in lab. They
function by having visible light pass through an object, and then glass lenses enlarge the object.
b. Electron microscopes use beams of electrons. They have better resolving and magnification
capabilities that allow us to see organelles and their parts. 3. Cell Theory states that all living
things & come from other cells. This theory developed as a result of contributions of 5 people
van Leeuwenhoek- 1 microscope in the 17 century b. Robert Hooke was the first person to use
the term cell to describe the basic structure of living organisms. When observing cork he noticed
that it was full of small room like structures. These structures resembled the cells that monks
lived in thus he coined the term cell in relationship Schleiden-plants are composed ofcells to
living organisms. d Schwann-animals are composed of cells e. Virchow-cells don\'t just appear
they come from preexisting cells. B. Two major classes of cells. which is coiled in region where
the nuc leus would be if the cell had a nucleus. This group includes the archaea and bacteria have
a true nucleus which is bordered by a double membrane called the nuclear enve lop. This group
includes the protists, fungi, plants, and animals collectively known as the Eukarya.
Characteristics of eukaryot ic cells A. Cytoplasm is the space in a cell between the It contains
organelles within a fluid called B. Membrane Structure and Function 1. The serves as the border
of the cell. Its unique structure allows it to regulate what enters and exits a cell, for this reason it
is oft called the gate keeper 2. Membrane Structure pecialized lipids known as make up most of
the membrane. These structures have a or water loving head that is made of a phosphate group
and two x I N
Solution
1. Developmet of microscope enabled the study of cells. Microscopes are two types light or
compound microscope and electronic microscope.
2. In a compound light microscope the high power objective lens comes close to the specimen to
magnify the image. Transmission electron microscopy (TEM) depends on the electron beam of
short wavelength to illuminate the internal structures of microorganisms. The electron beam
penetrates into the specimen and magnifies 1nm object up to 500,000X. In scanning electron
microscopy (SEM) the specimen is coated with a thin layer of heavy metal like gold or
palladium. The narrow beam of electrons probe back and forth of the metal coated specimen.
The secondary electrons that are scattered back give the image of the specimen which is
displayed on the screen.
3. According to cell theory living things are composed of one or more cells. Anton von
Leeuwenhoek (1632-1723) is considered as “Father of Microbiology”. He was the f.
1CHAPTER 1 Microbiology Then and NowCHAPTER 2 The Che.docx
1
CHAPTER 1 Microbiology: Then and Now
CHAPTER 2 The Chemical Building Blocks of Life
CHAPTER 3 Concepts and Tools for Studying Microorganisms
CHAPTER 4 Cell Structure and Function in the Bacteria and Archaea
CHAPTER 5 Microbial Growth and Nutrition
CHAPTER 6 Metabolism of Microorganisms
CHAPTER 7 Control of Microorganisms: Physical and Chemical Methods
1 Foundations of Microbiology
P A R T
n 1676, a century before the Declaration of Independence, a Dutch
merchant named Antony van Leeuwenhoek sent a noteworthy let-
ter to the Royal Society of London. Writing in the vernacular of his
home in the United Netherlands, Leeuwenhoek described how he used a simple
microscope to observe vast populations of minute, living creatures. His reports
opened a chapter of science that would evolve into the study of microscopic
organisms and the discipline of microbiology. At that time, few people, including
Leeuwenhoek, attached any practical significance to the microorganisms, but
during the next three centuries, scientists would discover how profoundly these
organisms influence the quality of our lives and the environment around us.
We begin our study of the microorganisms by exploring the grassroot devel-
opments that led to the establishment of microbiology as a science. These devel-
opments are surveyed in Chapter 1, where we focus on some of the individuals
who stood at the forefront of discovery. Today we are in the midst of a third Golden Age of microbiology and our
understanding of microorganisms continues to grow even as you read this book. Chapter 1, therefore, is an important
introduction to microbiology then and now.
Part 1 also contains a chapter on basic chemistry, inasmuch as microbial growth, metabolism, and diversity
are grounded in the molecules and macromolecules these organisms contain and in the biological processes they
undergo. The third chapter in Part 1 sets down some basic concepts and describes one of the major tools for study-
ing microorganisms. Much as the alphabet applies to word development, in succeeding chapters we will formulate
words into sentences and sentences into ideas as we survey the different groups of microorganisms and concentrate
on their importance to public health and human welfare.
Although most microorganisms are harmless—or even beneficial, some cause infectious disease. We will concentrate
on the bacterial organisms in Chapter 4, where we survey their structural frameworks. In Chapter 5, we build on these
frameworks by examining microbial growth patterns and nutritional requirements. Chapter 6 describes the metabolism
of microbial cells, including those chemical reactions that produce energy and use energy. Part 1 concludes by consider-
ing the physical and chemical methods used to control microbial growth and metabolism (Chapter 7).
I
Cells of Vibrio cholerae, transmitted to
humans in contaminated water and food, are
the cause of cholera.
62582_CH01_001_034.pdf 162582.
microbiology introduction, definition, terminology, history, scope ,importanc...
This is pdf file knowledge for microbiology in fungi , virus , bacteria , Protozoa
Distinguish between cellular and acellular. Give examples of microorg.pdf
Distinguish between cellular and acellular. Give examples of microorganisms in each category.
Describe the distinguishing features of each type of cell. What are the three domains of life?
Describe features of each domain. Escherichia coli is a bacterial species. Identify the genus and
the species. Escherichia coli has different strains. What is the significance of the strain
designation? What contributes to the emergence and/or re-emergence of infectious diseases?
Define the divisions of microbiology: bacteriology, mycology, virology, parasitology, serology,
molecular biology. The following made significant contributions to the field of microbiology,
identify the contribution of each: Leeuwenhoek, Holmes, Semmelweis, Lister, Pasteur, Koch,
Jenner
Solution
2.Unicellular organism is made up of one cell, a being with a cell wall, that gets along fine on its
own (like amoebas, protozoa or bacteria that usually move about all on their own) or which
could get along fine on its own (like yeasts or algae, which usually grow in bunches or
strings).Acellular organisms do not divide into discrete cells following the division of the
nucleus - they just carry on growing and producing more nuclei.Eg:Viruses, viroids, satellites,
plasmids, phagemids, cosmids, transposons and prions.
3. please specify the cells,in human or microbes?
4.The three domains of life are:
(a)EUKARYOTA
The Eukaryota include the organisms that most people are most familiar with - all animals,
plants, fungi, and protists. They also include the vast majority of the organisms that
paleontologists work with. Although they show unbelievable diversity in form, they share
fundamental characteristics of cellular organization, biochemistry, and molecular biology. Eg:
dinoflagellate,single-celled photosynthetic protist; plants; animals; and fungi.
(b)BACTERIA
Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira,
which causes serious disease in livestock). However, certain bacteria, the actinomycetes, produce
antibiotics such as streptomycin and nocardicin; others live symbiotically in the guts of animals
(including humans) or elsewhere in their bodies, or on the roots of certain plants, converting
nitrogen into a usable form. Bacteria put the tang in yogurt and the sour in sourdough bread;
bacteria help to break down dead organic matter; bacteria make up the base of the food web in
many environments. Bacteria are of such immense importance because of their extreme
flexibility, capacity for rapid growth and reproduction, and great age - the oldest fossils known,
nearly 3.5 billion years old, are fossils of bacteria-like organisms.
(c)ARCHEA
Archaeans include inhabitants of some of the most extreme environments on the planet. Some
live near rift vents in the deep sea at temperatures well over 100 degrees Centigrade. Others live
in hot springs, or in extremely alkaline or acid waters. They have been found thriving inside the
digestive tracts of cows, t.
What is greenhouse gasses and how many gasses are there to affect the Earth.
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
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history of microbiology
Koch's Postulates
scopes of microbiology
importance of microbiology
branches of microbiology
medical microbiology
types of microorganisms
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virology
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mycology
immunology
brief introduction about microscope & its types
Introduction to microbiology
A brief introductory overview of microbiology subject matter and what it includes. This presentation and the following was teaching undertaken for Allied Health Sciences BSc as part of my postgraduate degree.
A. The development of the has allowed us to study cells and their pro.pdf
A. The development of the has allowed us to study cells and their processes 1. T a. Resolution is
the ability ofamicroscope to show two objects as separate Magnification is how much larger an
object appears compared to its actual size a Light microscopes are the kind we use in lab. They
function by having visible light pass through an object, and then glass lenses enlarge the object.
b. Electron microscopes use beams of electrons. They have better resolving and magnification
capabilities that allow us to see organelles and their parts. 3. Cell Theory states that all living
things & come from other cells. This theory developed as a result of contributions of 5 people
van Leeuwenhoek- 1 microscope in the 17 century b. Robert Hooke was the first person to use
the term cell to describe the basic structure of living organisms. When observing cork he noticed
that it was full of small room like structures. These structures resembled the cells that monks
lived in thus he coined the term cell in relationship Schleiden-plants are composed ofcells to
living organisms. d Schwann-animals are composed of cells e. Virchow-cells don\'t just appear
they come from preexisting cells. B. Two major classes of cells. which is coiled in region where
the nuc leus would be if the cell had a nucleus. This group includes the archaea and bacteria have
a true nucleus which is bordered by a double membrane called the nuclear enve lop. This group
includes the protists, fungi, plants, and animals collectively known as the Eukarya.
Characteristics of eukaryot ic cells A. Cytoplasm is the space in a cell between the It contains
organelles within a fluid called B. Membrane Structure and Function 1. The serves as the border
of the cell. Its unique structure allows it to regulate what enters and exits a cell, for this reason it
is oft called the gate keeper 2. Membrane Structure pecialized lipids known as make up most of
the membrane. These structures have a or water loving head that is made of a phosphate group
and two x I N
Solution
1. Developmet of microscope enabled the study of cells. Microscopes are two types light or
compound microscope and electronic microscope.
2. In a compound light microscope the high power objective lens comes close to the specimen to
magnify the image. Transmission electron microscopy (TEM) depends on the electron beam of
short wavelength to illuminate the internal structures of microorganisms. The electron beam
penetrates into the specimen and magnifies 1nm object up to 500,000X. In scanning electron
microscopy (SEM) the specimen is coated with a thin layer of heavy metal like gold or
palladium. The narrow beam of electrons probe back and forth of the metal coated specimen.
The secondary electrons that are scattered back give the image of the specimen which is
displayed on the screen.
3. According to cell theory living things are composed of one or more cells. Anton von
Leeuwenhoek (1632-1723) is considered as “Father of Microbiology”. He was the f.
1CHAPTER 1 Microbiology Then and NowCHAPTER 2 The Che.docx
1
CHAPTER 1 Microbiology: Then and Now
CHAPTER 2 The Chemical Building Blocks of Life
CHAPTER 3 Concepts and Tools for Studying Microorganisms
CHAPTER 4 Cell Structure and Function in the Bacteria and Archaea
CHAPTER 5 Microbial Growth and Nutrition
CHAPTER 6 Metabolism of Microorganisms
CHAPTER 7 Control of Microorganisms: Physical and Chemical Methods
1 Foundations of Microbiology
P A R T
n 1676, a century before the Declaration of Independence, a Dutch
merchant named Antony van Leeuwenhoek sent a noteworthy let-
ter to the Royal Society of London. Writing in the vernacular of his
home in the United Netherlands, Leeuwenhoek described how he used a simple
microscope to observe vast populations of minute, living creatures. His reports
opened a chapter of science that would evolve into the study of microscopic
organisms and the discipline of microbiology. At that time, few people, including
Leeuwenhoek, attached any practical significance to the microorganisms, but
during the next three centuries, scientists would discover how profoundly these
organisms influence the quality of our lives and the environment around us.
We begin our study of the microorganisms by exploring the grassroot devel-
opments that led to the establishment of microbiology as a science. These devel-
opments are surveyed in Chapter 1, where we focus on some of the individuals
who stood at the forefront of discovery. Today we are in the midst of a third Golden Age of microbiology and our
understanding of microorganisms continues to grow even as you read this book. Chapter 1, therefore, is an important
introduction to microbiology then and now.
Part 1 also contains a chapter on basic chemistry, inasmuch as microbial growth, metabolism, and diversity
are grounded in the molecules and macromolecules these organisms contain and in the biological processes they
undergo. The third chapter in Part 1 sets down some basic concepts and describes one of the major tools for study-
ing microorganisms. Much as the alphabet applies to word development, in succeeding chapters we will formulate
words into sentences and sentences into ideas as we survey the different groups of microorganisms and concentrate
on their importance to public health and human welfare.
Although most microorganisms are harmless—or even beneficial, some cause infectious disease. We will concentrate
on the bacterial organisms in Chapter 4, where we survey their structural frameworks. In Chapter 5, we build on these
frameworks by examining microbial growth patterns and nutritional requirements. Chapter 6 describes the metabolism
of microbial cells, including those chemical reactions that produce energy and use energy. Part 1 concludes by consider-
ing the physical and chemical methods used to control microbial growth and metabolism (Chapter 7).
I
Cells of Vibrio cholerae, transmitted to
humans in contaminated water and food, are
the cause of cholera.
62582_CH01_001_034.pdf 162582.
microbiology introduction, definition, terminology, history, scope ,importanc...
This is pdf file knowledge for microbiology in fungi , virus , bacteria , Protozoa
Distinguish between cellular and acellular. Give examples of microorg.pdf
Distinguish between cellular and acellular. Give examples of microorganisms in each category.
Describe the distinguishing features of each type of cell. What are the three domains of life?
Describe features of each domain. Escherichia coli is a bacterial species. Identify the genus and
the species. Escherichia coli has different strains. What is the significance of the strain
designation? What contributes to the emergence and/or re-emergence of infectious diseases?
Define the divisions of microbiology: bacteriology, mycology, virology, parasitology, serology,
molecular biology. The following made significant contributions to the field of microbiology,
identify the contribution of each: Leeuwenhoek, Holmes, Semmelweis, Lister, Pasteur, Koch,
Jenner
Solution
2.Unicellular organism is made up of one cell, a being with a cell wall, that gets along fine on its
own (like amoebas, protozoa or bacteria that usually move about all on their own) or which
could get along fine on its own (like yeasts or algae, which usually grow in bunches or
strings).Acellular organisms do not divide into discrete cells following the division of the
nucleus - they just carry on growing and producing more nuclei.Eg:Viruses, viroids, satellites,
plasmids, phagemids, cosmids, transposons and prions.
3. please specify the cells,in human or microbes?
4.The three domains of life are:
(a)EUKARYOTA
The Eukaryota include the organisms that most people are most familiar with - all animals,
plants, fungi, and protists. They also include the vast majority of the organisms that
paleontologists work with. Although they show unbelievable diversity in form, they share
fundamental characteristics of cellular organization, biochemistry, and molecular biology. Eg:
dinoflagellate,single-celled photosynthetic protist; plants; animals; and fungi.
(b)BACTERIA
Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira,
which causes serious disease in livestock). However, certain bacteria, the actinomycetes, produce
antibiotics such as streptomycin and nocardicin; others live symbiotically in the guts of animals
(including humans) or elsewhere in their bodies, or on the roots of certain plants, converting
nitrogen into a usable form. Bacteria put the tang in yogurt and the sour in sourdough bread;
bacteria help to break down dead organic matter; bacteria make up the base of the food web in
many environments. Bacteria are of such immense importance because of their extreme
flexibility, capacity for rapid growth and reproduction, and great age - the oldest fossils known,
nearly 3.5 billion years old, are fossils of bacteria-like organisms.
(c)ARCHEA
Archaeans include inhabitants of some of the most extreme environments on the planet. Some
live near rift vents in the deep sea at temperatures well over 100 degrees Centigrade. Others live
in hot springs, or in extremely alkaline or acid waters. They have been found thriving inside the
digestive tracts of cows, t.
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Cell utilize energy in the form of ATP.
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Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
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What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
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Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
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Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
SCHIZOPHRENIA Disorder/ Brain Disorder.pdf
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Nutraceutical market, scope and growth: Herbal drug technology
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Citrus Greening Disease and its Management
Citrus Greening was one of the major causes of decline in the citrus production. So, effective management cultural practices should be incorporated
extra-chromosomal-inheritance[1].pptx.pdfpdf
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
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