This is for the D.pharm students who wants to quick revision and wants all content at one place

1. Introduction to Pharmaceutical chemistry
Sources and types of errors
Definition: Pharmaceutical chemistry deals with the
structure, chemical nature, composition,
preparation, studies of physical and chemical
properties, methods of quality controls and
conditions of their uses.
Prepared By – Kartik Tiwari (Lecturer)
Hygia College of Pharmacy, Lucknow (U.P)
Content as Per D. Pharm Syllabus
Scope
 Clinical chemist
 Pharmacologist chemist
 Forensic chemist
 Hazardous material manager
 Laboratory technicians
 Environmental health officers
 Research assistant
 Chemo-therapist
 Scientist
Branches:
 Inorganic Pharmaceutical chemistry
 Organic Pharmaceutical chemistry
 Analytical chemistry
 Medicinal chemistry
Objectives
 To understand the various Structures and basic
chemical moiety of the drug.
 To know about drug metabolic pathway, adverse
effect, and therapeutic value of drug.
 To aware about the various classes drug’s
structural activity relationship (SAR).
 To make sense towards the use of drug and
their various mechanism of action.
 To analyze the content of drug present in the
sample.
 To aware about the identification of various
drugs.
Errors :
Errors is defined as the difference between the
exact value to the observed value during analytical
operations.
E = EV - OV
Sources of error:
1. Human source
2. Instrument and glassware
3. Procedure
4. Experiment conditions
5. Chemicals used for experiment
Classification of Errors:
1. Systemic Errors/ Determinant errors:
 Personal error
 Operational error
Example: Weighing, burette, solution transfer
 Instrumental error
Example: Wrong method, wrong indicator.
 Methodological error
Example: Wrong method, wrong indicator.
2. Random Error
Example: Pressure, Temperature, humidity that
cause change in final result.
3. Measurement Error
Example: suppose 2g sample weigh if we take it 3g
without paying attention in the measurement.
4. Gross Error
Example: Wrong formula, Wrong method