Caron D'Ambruso is an experienced medical marketing and sales executive with over 30 years of experience leading marketing and sales initiatives for major medical device companies. She has a track record of successfully launching new products, growing businesses, and gaining market share. Her expertise includes branding, relationship building, strategic planning, product development, and sales management.

1. Caron D’Ambruso … a gifted upstream and downstream marketing professional with combined start-up, emergent, and fortune 500 class expertise. Her proficiency is branding corporations and their products as well as cultivating vital relationships with practitioners, sales and marketing teams, and executive colleagues. She is an effectual leader that consistently delivers profitable platforms for brand innovations and advantages. Industry Relationship Development Proactive Market Analysis Portfolio Development Transformational Technology Sales Pilot Studies / Safety Trials Brand Loyalty Cultivation Portfolio Development / Management Strategic Planning / Alliances Product Development / Launch Physician Relationship Building Opinion Leader Meetings Sales / Marketing Management (954) 610-9363 [email_address] 103 Sunset Point, 3227 Seven Lakes West, West End, NC 27376 Location Negotiable Medical Marketing And Sales Executive

2. Campaign Successes Ignited business from $3M to $16M in first year. Elevated company from last in market to second within two months and secured incremental new revenue of over $262M, a 242% increase vs. previous year. Captured #1 market share position by instituting the first .086” guiding catheter allowing passage of stents to target lesions. [Johnson & Johnson] Sold $7.4M in distal protection devices, provided training to interventional cardiology radiologists, and secured a partner to sell product through a larger corporation. [Scion Cardio-Vascular, Inc.] Vaso-Seal Elite – regained 5 market share points. [Datascope, Inc.] Angio-Seal Elite – raised price but still gained 10% additional share. [St. Jude Medical] Took Kensey Nash form an unknown in cardiology to a player through great branding, opinion leader development, and a clinical trial with the top investigators in the country. When the TCT was canceled in 2001, I had the only live product webcast demonstration. Of 1000 invited, over 1200 attend. Vascular Closure Angio-Seal 2006 Angio-Seal Elite 954-610-9363 Location Negotiable [email_address] CARON D’AMBRUSO 103 Sunset Point, 3227 Seven Lakes West, West End, NC 27376 Patents US-2007-0080688A1 Animal Waste Receptacle 5,417,669 Guiding Catheter Exchange and Apparatus 97303332.7 7- 2305 European Guiding Catheters 5,658,262 Guiding Catheter Method Education Harvard University BA, Economics (Cum Laude) Newton Wellesley School of Nursing Licensed Registered Nurse Registered in Arrhythmia Management and Pulmonary Disease Product Launch History Product Launch Product Replaced Market Served Pulse 5 1986 Dorros 5 French Peripheral Trakstar 1993 Atlas Coronary Olympix 1992 Trakstar Coronary Titan 1995 New on Market Coronary/ Stent delivery 8 French Guide .089 1993 8 French .078 Coronary /Stent delivery 9 French Guide 1993 New to market Coronary Peripheral Arterectomy Powerflex 1992 New to market Peripheral Powerflex Plus 1994 Powerflex Peripheral Savvy 1996 New to Market Peripheral below the knee TriActiv 2002 New to Market Distal Protection w/ Flush & Extraction Vaso-Seal Elite 2003 Vaso-Seal Arteriotomy Closure SafeGuear 2003 New to Market Manual Compression LifesSync 2005 New to market Wireless EKG Page 1

3. 954-610-9363 D’Ambruso Medical Sales and Marketing Experience Position Company Responsibilities Date Director Of Marketing Development ATEX TECHNOLOGIES, INC . 120 W. Monroe Av. Pinebluff, NC 28373 atextechnologies.com Implantable textile company working in fields of cardiology, orthopedic, spine, and woman’s health. Responsible for finding new areas of medicine using medical textiles including left ventricular assist devices, wound closure, patent foramen ovale closure and prosthetic heart valves. Contact companies that can use our services. Provide market research for new product categories. Provide Market Analysis and presentation to executive board. Products include cardiac, orthopaedic, male and female reproductive system and spine. 2008 to Present Vice President of Product Innovation and Marketing Services INSTITUTE FOR PEDIATRIC INNOVATION One Broadway, Floor 14 Cambridge, MA 02142 Pediatricinnovation.org Non-Profit company with for profit activities including branding, market research, lobbying insurers, brochure and website development for pediatric market segment. Responsible for all aspects of marketing including lobbying, fundraising, research (primary and secondary; quantitative and qualitative), branding and website development, and brochure positioning and message building. Handled all aspects of marketing independently until non-profit raised more funding. Raised over $1.1 million. 2007 Senior Director of Marketing ST. JUDE MEDICAL St. Paul, MN Austin, TX Dallas, TX SJM.com Develops medical technology and services that focus on cardiac, neurological and chronic pain patients worldwide. Held full responsibility for performance of Angio-Seal Vascular Sealing Device in a declining market. Leveraged market analysis expertise to allow company to proactively respond to multiple new competitors. 2006 Left with corporate restructure. Page 2

4. 954-610-9363 D’Ambruso Medical Sales and Marketing Experience Position Company Responsibilities Date Vice President of Sales and Marketing SCION CARDIO-VASCULAR, INC. 14256 S.W. 119 Avenue Miami, FL 33186 Scioncv.com Start-up medical device company preparing for IPO with focus on sales / distribution of SciPro Filter Protection Device. Delivered clinical trial / marketing plans for all Company products and directed marketing / sale of filter protection device. Initiated relationship with Fox Hollow to coordinate the use of a distal protection device with Talon Silverhawk. Sold $7.4M in distal protection devices and provided training to interventional cardiology radiologists. Established Clinical Advisory Board with top US and international physicians. 2004 to 2006 Vice President of Marketing GMP WIRELESS MEDICAL 10601 State St #8 Tamarac, FL 33321 Lifesynccorp.com (new entity) Privately-held development company whose historical mission was to acquire, develop and commercialize novel pharmaceutical, medical device and diagnostic technologies. Worked in products in laparoscopy, cancer diagnostics, gene therapy, spinal repair and ophthalmology. Released LifeSyncTM Wireless EKG monitoring system to the market and managed tradeshow, web development, marketing communications for release of the product. Wrote clinical paper on wireless protocol 8.11b and g for successful launch support. Company did not receive financing after first year and was unable to go public and ultimately spun off the company as a separate entity. 2004 to 2005 Director of Marketing DATASCOPE, INC. 14 Philips Parkway, Montvale, NJ 07645 Datascope.com Medical Device Manufacturer with monitoring, Intra-Aortic Balloon Pump and Interventional Cardiology products. Launched 3 new products in vascular closure market. Assisted with new business development role seeking new products for acquisition. Reviewed over 75 new products and purchased two devices in a six month period. Forecasting for Vaso-Seal™ Elite and new product offerings. 2003 to 2004 Page 3

5. 1996 to 1998 Promoted to manage a portfolio of all new products in Gynecare division’s technology pipeline. Devised cost containment / multi-center reimbursement studies for Europe; published in a peer review journal. Developed a top advisory panel and product champions for publishing, abstracts and clinical trial multi-center paper. ETHICON, INC Route 22 West Somerville, NJ 08876 Ethicon.com Dedicated to providing innovative treatments for urologic and women's health conditions. Director of Market Portfolio Development Gynecare 1992 to 1998 JOHNSON & JOHNSON JNJ.com The world's most comprehensive and broadly based manufacturer of health care products and services. 954-610-9363 D’Ambruso Medical Sales and Marketing Experience Position Company Responsibilities Date Vice President of Worldwide Sales and Marketing KENSEY NASH CORP. 735 Pennsylvania Drive Exton, PA Macropore.com Kensey Nash Corporation is a medical device company and a pioneer in the development of a wide variety of products for the cardiovascular, endovascular, sports medicine, spine and trauma marketplaces. Launched first direct cardiology sales/clinical force in company history for the TriActive® distal protection balloon. Developed strategy to market cardiovascular and biomaterials product lines, and created strategic plan for lithotripsy market. Provided portfolio direction to R&D team for future product line implementation. Created branding and a consistent corporate identity. 1998 to 2003 Marketing Communi- cations Director Endovascular CORDIS 430 Route 22 East Bridgewater, NJ 08807 Cordis.com Cordis Endovascular is a leader in providing breakthrough treatment solutions for peripheral vascular disease. Led team of three product managers responsible for new endovascular division. Established incentive programs, territory alignments, and training programs for Sales Developed advisory panel and managed clinical process. Drove sales to achieve $26.2M in revenues, a 242% increase vs. previous year. 1995 to 1996 Page 4

6. 1994 Directed portfolio management, launch management, and market development for multimillion-dollar interventional neuro-radiology and endovascular business. Analyzed market to identify new trends, evaluated products in development, conducted market research to ensure specifications aligned with market needs, and pre-tested marketing brochures in the field. Chose the key opinion leader board and coordinated KOL meeting logistics. CORDIS 430 Route 22 East Bridgewater, NJ 08807 Cordis.com Cordis Endovascular is a leader in providing treatment solutions for peripheral vascular disease. Marketing Manager CES Division 1993 to 1995 Led portfolio management / market development for multimillion-dollar interventional neuroradiology device. Managed sales and production forecasting, sales call analysis, customer programs, and the development of sales tools for the endovascular device market. Supervised seven product managers. Ignited business from $3M to $16M in first year. CORDIS 430 Route 22 East Bridgewater, NJ 08807 Cordis.com Cordis Endovascular is a leader in providing treatment solutions for peripheral vascular disease. Group Marketing Director Endovascular 1992 to 1998 JOHNSON & JOHNSON JNJ.com (continued from page 4) The world's most comprehensive and broadly based manufacturer of health care products and services. 954-610-9363 D’Ambruso Medical Sales and Marketing Experience Position Company Responsibilities Date Portfolio Manager CORDIS 430 Route 22 East Bridgewater, NJ 08807 Cordis.com Cordis Endovascular is a leader in providing treatment solutions for peripheral vascular disease. Elevated company from last in market to second within two months and secure incremental new revenue of over $262M by initiating Titan Balloon. Captured #1 market share position by instituting the first .086” guiding catheter allowing passage of stents to target lesions. 1992 to 1994 Page 5

7. (names of physicians and hospitals) Key Customer Relationships 954-610-9363 D’Ambruso Medical Sales and Marketing Experience Position Company Responsibilities Date Sr. Product Manager Product Manager Associate Product Manger USCI C.R. BARD 55 Technology Drive Lowell, MA 01851 Crbard.com Luminary interventional cardiology catheter company acquired by C.R. Bard, and eliminated in 1998 to refocus on endovascular business line. COMPLETE THIS SECTION… 1986 to 1992 Field Trainer Sr. Sales Rep Sales Rep JANSSEN PHARMACEUTICA A Johnson & Johnson Co. Titusville, NJ Janssen.com Sold product portfolio to New England Hospitals, as well as Boston teaching hospitals. WHAT TRAINING/EDUC DID YOU DO? 1982 to 1986 Previously served as a Registered Nurse in cardiac / neurological intensive care units Key Words: Page 6