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This document discusses how micro and nanotechnologies can contribute to progress in neuroscience. It describes how technologies like MOS transistors and nanoionics/nanoelectronics can help study the structure and function of synapses at the nanoscale level. Potential applications include using these technologies to better understand basic neuroscience, as well as in clinical areas like neuronal regeneration, neuroprotection, neuromodulation, and high resolution imaging. The document advocates for an interdisciplinary approach involving neurobiologists, neurologists, engineers, and materials scientists to identify potential applications and focus technology development efforts in order to maximize the impact of these technologies and further progress in understanding the brain.











