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Respiratory Inductance
Plethysmography

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
RIP Applications
• Research
Over 1000 Research papers published.
Chimes Study

• ICU
Non Invasive Monitoring of FRC changes in Ventilated patients
Apnea monitoring

• SLEEP!!!

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.

Adobe
Acrobat Document
ASSM Scoring Rules

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
MOVEMENTS OF THE THORACIC CAGE AND
DIAPHRAGM IN RESPIRATION
by 0. L. WADE J. Physiol. (I954)
Fig. 1. Diagram showing
the method of tracking
diaphragmatic movement
and of recording
vertical movements of the
chest and changes of chest
circumference. Inset
diagram
illustrates the geometric
distortion for which
corrections were made.

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
Measurement of the separate volume changes of rib
cage and abdomen during breathing
KIMIO KONNO AND JERE MEAD J. Appl.Physiol. 22(3) : 407-422. I967

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
NIMS Respitrace Corp

Introduction of Respitrace Basic 1979

(still available from Ambulatory Care Inc)

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
Herman Watson 1/5/1982
Respitrace Corp

Respiratory Inductive Plethysmography

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History

Herman Watson 2/15/1983
Respitrace Corp

Calibration of RIP

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History

QDC
Qualitative Diagnostic Calibration
MARVIN A SACKNER, HERMAN WATSON,
ANNE S. BELSITO, DREW FEINERMAN,
MANUEL SUAREZ, GERARDO GONZALEZ,
FRANKLIN BIZOUSKY, AND BRUCE KRIEGER.

September 8 1988
Calibration of respiratory inductive
plethysmography during natural
breathing
QDC Calibration
5 Minutes of Normal Resting Breathing….
To calibrate RIP to volume change (ΔV) the qualitative diagnostic calibration (QDC)
procedure uses the equation ΔV = M * (K * ΔRIPrc + ΔRIPab), in which ΔRIPrc and
ΔRIPab are the rib cage and abdominal RIP changes relative to the values at FRC,
respectively. K is a calibration factor, indicating the relative contribution of both
compartments to volume, and M scales the sum to volume and is expressed in ml. ( M is
determined in a second stage Calibration to a pneumotach)
In the QDC method, a number of undisturbed breaths are collected during 5 minutes
uninterrupted mechanical ventilation. Breaths with similar tidal volume are selected, based
on the uncalibrated sum signal (RIPrc+RIPab), including only breaths within one standard
deviation of the mean. Then, the standard deviations of RIPrc and RIPab are determined
over the selected breaths. Calibration factor K is estimated by SD(RIPab) / SD(RIPrc). M is
determined by injection of a known volume, e.g. tidal volume. With M and K known,
every pair of RIPab and RIPrc are converted to a calibrated volume.
History
• NIMS
• September 1991 introduces Respitrace Plus
Respitrace Plus monitors breathing pattern and the
electrocardiogram. It incorporates NIMS' patented Respitrace
technology for assessment of respiratory frequency, changes
of tidal volume, labored breathing and detection of central
and obstructive apneas. Respitrace is the only commercially
available technology that by itself is capable of monitoring
these parameters

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• NIMS – SensorMedics Agreement
• August 2 1994
• Respitrace PT2
• Respitrace Plus
• Respitrace Cardio
• Respibands

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• SensorMedics / VIASYS
– April 1999
– Qualitative Diagnostic Calibration
• 5 minutes Normal Resting Breathing

– Calibrated SUM channel
– FVL with RespiEvents Software
– dVt Channel (Derived Flow) in 2002
– FVL integrated into Somnostar in 2002

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• Compumedics
• David Burton
• Jiang Hong Tan
• Patent # 6142953 November 2000
A device for reliably and non-invasively measuring respiration rates and effort by encircling the patient's chest with a device
having a large section of inelastic belt attached to a small section of elastic material. The elastic material having two magnetic
tapes with wire windings thereon proximate each other with an insulation material therebetween. The wire windings are
electrically connected to each other. The magnetic tapes have opposite ends attached to the elastic material such that when the
elastic material expands and contracts the wire windings move relative to each. A toroidal transformer is connected to the wire
windings. When a carrier signal is introduced to the transformer and the magnetic tapes move relative to each other on the
elastic material when the patient breathes a mutual inductance in the wire windings modulates the carrier signal and thus
measures the expansion and contraction of the patient's chest which is directly related to the patient's respiration rate. The
electronics connected to the device for monitoring respiration also measures belt shifting for diameter changes during
monitoring by measuring the central amplitude during a breath cycle and comparing the initial belt diameter conditions to later
conditions. The electronics can then compensate for amplitude variations in the signal caused by belt shifting which may be
confused with shallower breathing in uncompensated devices.

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• Compumedics 2000
•
•
•
•
•
•
•
•

•
•
•
•
•
•
•
•

Inductive plethysmography technology
Linear response to changes in effort
Balanced SUM channel output
Continuous, automatic channel balancing
Operates with any PSG amplifier system
800 hours of operation from a small low-cost battery
Long lasting, reusable sensor bands
Cost effective and easy to use

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• Embla 2005
•
•
•
•
•
•
•
•
•
•
•
•
•
•

• XFlow™ is a semi-quantitative measure of inspiratory and
expiratory flow, providing a complementary flow signal
for studies without airflow sensors. X-flow is a reliable
backup and great tool for titrations.
• XSum™ is the summation of the abdominal and thoracic
signals providing a semi-quantitative measurement of
lung volume.
• RMI™ (Respiratory Mechanics Instability) is a proprietary
algorithm that assesses the severity of Sleep Disordered
Breathing by analyzing the phase relationship between
the abdomen and thorax.
• Phase Analysis displays (in degrees) the phase relationship
between the abdomen and the thorax for evaluation and
analysis of paradoxical breathing.

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• Pro Tech June 2005
• zRIP
– Compatible with all PSG systems
– Washable belts
– Non-calibrating SUM channel

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• Braebon

2006

• Q-RIP
– Compatible with all PSG systems
– Non-calibrating SUM channel

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
History
• Sleepmate 2007
• RIPmate
– Compatible with all PSG systems
– Non-calibrating SUM channel

The RIPmate system is designed with a washable one-size-fits-all belt
and buckle that is comfortable and stays in place. The RIPmate
Inductance Processor module plugs directly into the AC input of any
headbox with no additional software needed. The system provides a
reliable effort signal that eliminates the problems of effort signal loss
and false paradoxical signals.

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Comparison Piezo Belts

– Poor QUALITATIVE grading of waveform
• NOT Quantitative

– False Paradox due to low signal
– Must be readjusted throughout night
– Loss of signal due to position shift

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Comparison Non Calibrated RIP
•False paradox eliminated
(if reference and signal inputs must be connected with the same polarity).

•Excellent signal quality
•Small interface device (usually battery operated)
•Sum channel not equal to true RC + ABD volume change

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Comparison Calibrated RIP
• False paradox eliminated
•Excellent signal quality
•Larger driver/interface device (usually AC operated)
•Sum channel equal to true RC + ABD volume change
•dVt
•FVL
•Konno Mead Loops
• QUANTITATIVE

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Device Comparison

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Obstructive Apnea
No Flow

Paradoxical
Effort

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Central Apnea

No Flow!

No Volume!

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.

No Patient Effort
Hypopneas - Non Calibrated RIP

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Hypopneas – Calibrated RIP with
FVL

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Hypopnea
• Take the guesswork out of
Hypopneas!
• Quantify the
difference of
percentage of
breaths against
the Baseline
Breath

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Inspiratory Flow Limitation - UARS
• Flattening on the Inspiratory Side
of the Flow Volume Loop
vs.
• Chest and Abdomen out of
Phase

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Inspiratory Flow Limitation UARS
Flattening of dVt Channel

Flattening of Chest Signal

Increased I:E Ratio

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.

Flattening of Inspiratory Curve
CPAP TITRATION
The first step to compliance is proper Titration
Eliminate all obstructive and events
• Gross titration by stepwise increases in PAP until no events
are observed via Thermocouple/Nasal Pressure and effort
belts.
Elimination of UARS
• Fine titration of stepwise increases in PAP until Airway is
splinted open observed via Flow Volume Loops or Esophageal
Pressure.
Elimination of Central Events caused by over titration

• Observe FVLs for hyperinflation
Elimination of increased WOB / increased Expiratory Resistance

• Treat Flattening of expiratory curve with Pressure
Release

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
How can cRIP Help ?
Flow Volume Loops
–

Breath used as the “Signature Breath”
• Select a Baseline Breath at Sleep Onset

–

Compare breaths to the Baseline Breath
• CPAP Titrations
– Titrate sleep patients back to their “Signature Breath

• UARS Visualize Inspiratory Flow Limitation1
• Hypopnea Events
– Show a difference or a percentage as compared to the
Baseline Breath
– Differentiate between Mixed, Obstructive and Central
Hypopneas2
1 Daniel Loube, MD, FCCP, Teotimo Andrada, MS. Pulmonary/Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC, USA COMPARISON OF
RESPIRATORY INDUCTANCE PLETHYSMOGRAPHY AND ESOPHAGEAL PRESSURE MONITORING IN THE DETECTION OF UPPERAIRWAY RESISTANCE SYNDROME
2 Classification of a hypopnea as obstructive, central or mixed should not be performed without a quantitative assessment of ventilatory effort (esophageal manometry, calibrated
respiratory inductance plethysmography, or diaphragmatic/intercostal EMG) ASSM Manual for the Scoring of Sleep and Associated Events

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
How can cRIP Help ?
Konno Mead Loops
–

Work of Breathing
• Visualize accessory muscle use vs. diaphragmatic effort
• Monitor Increased Expiratory Resistance during titrations

–

Chest/Abdominal Asynchrony
• Phase Angle shift

–

Central vs. Obstructive events
• True Paradox

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Konno Mead Loop Breakdown
R
i
b
C
a
g
e

Expiration
Inspiration

Abdomen
© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
How can cRIP Help ?
Breath by Breath Tabular View
– Monitor I:E Ratios Inspiratory/Expiratory times
• Inverse I:E ratios indicate increased Inspiratory Resistance

– Pif-Mif Peak Inspiratory Flow/Mean Inspiratory Flow
• Peak flow greater than the mean flow implies a work rate
greater than a constant flow1. <1.5 = inspiratory flow
limitation1

– Selection of multiple breaths for comparison and
printing

1. Lafortuna CL, Minetti AE, Mognoni P. Inspiratory pattern in
humans. J Appl Physiol 1984;57:1111-1119.

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP

Select a reproducible breath

Normal FVL

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP

Titrate to Eliminate Events

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP
Eliminate UARS
Titrate PAP to Open Loop

Inspiratory Resistance

(UARS)

Inverse I:E ratio
Increased WOB

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP

• Titrate Inspiratory and Expiratory curves
separately to Baseline Breath with Bi-Level
• Optimize Expiratory Pressure Release to
decreased expiratory resistance using FVLs
and decrease WOB with Konno Mead Loops

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP
Titrate Bi-Level to Eliminate Hypoventilation

Titrate EPAP to Eliminate Events

Titrate IPAP to increase Vt

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP
Eliminate Expiratory Resistance

Titrate Pressure Release to Open Loop
Expiratory Resistance

Increased WOB

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
PAP Titration with cRIP
Eliminate Central Apneas Caused by Over Titration

Reduce Pressure to Decrease Vt
Central Apneas

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Successful Titration with cRIP
Elimination of Events
Elimination of UARS

Titrated Loops = Baseline Loop

No Hyperinflation

WOB returns to Baseline Level

Successful Titration = Better Compliance = Satisfied Customer
© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
Summary
• Long History of Research and Development
• Validated technique
• Available calibrated and uncalibrated
• Accurate event detection
• A better way to measure Effort
• Enhanced software packages with FVL and
Konno Mead Loops
• A better tool for titration

© 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.

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Respiratory Inductance Plethysmography Monitoring

  • 1. Respiratory Inductance Plethysmography © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 2. RIP Applications • Research Over 1000 Research papers published. Chimes Study • ICU Non Invasive Monitoring of FRC changes in Ventilated patients Apnea monitoring • SLEEP!!! © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved. Adobe Acrobat Document
  • 3. ASSM Scoring Rules © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 4. History MOVEMENTS OF THE THORACIC CAGE AND DIAPHRAGM IN RESPIRATION by 0. L. WADE J. Physiol. (I954) Fig. 1. Diagram showing the method of tracking diaphragmatic movement and of recording vertical movements of the chest and changes of chest circumference. Inset diagram illustrates the geometric distortion for which corrections were made. © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 5. History Measurement of the separate volume changes of rib cage and abdomen during breathing KIMIO KONNO AND JERE MEAD J. Appl.Physiol. 22(3) : 407-422. I967 © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 6. History NIMS Respitrace Corp Introduction of Respitrace Basic 1979 (still available from Ambulatory Care Inc) © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 7. History Herman Watson 1/5/1982 Respitrace Corp Respiratory Inductive Plethysmography © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 8. History Herman Watson 2/15/1983 Respitrace Corp Calibration of RIP © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 9. History QDC Qualitative Diagnostic Calibration MARVIN A SACKNER, HERMAN WATSON, ANNE S. BELSITO, DREW FEINERMAN, MANUEL SUAREZ, GERARDO GONZALEZ, FRANKLIN BIZOUSKY, AND BRUCE KRIEGER. September 8 1988 Calibration of respiratory inductive plethysmography during natural breathing
  • 10. QDC Calibration 5 Minutes of Normal Resting Breathing…. To calibrate RIP to volume change (ΔV) the qualitative diagnostic calibration (QDC) procedure uses the equation ΔV = M * (K * ΔRIPrc + ΔRIPab), in which ΔRIPrc and ΔRIPab are the rib cage and abdominal RIP changes relative to the values at FRC, respectively. K is a calibration factor, indicating the relative contribution of both compartments to volume, and M scales the sum to volume and is expressed in ml. ( M is determined in a second stage Calibration to a pneumotach) In the QDC method, a number of undisturbed breaths are collected during 5 minutes uninterrupted mechanical ventilation. Breaths with similar tidal volume are selected, based on the uncalibrated sum signal (RIPrc+RIPab), including only breaths within one standard deviation of the mean. Then, the standard deviations of RIPrc and RIPab are determined over the selected breaths. Calibration factor K is estimated by SD(RIPab) / SD(RIPrc). M is determined by injection of a known volume, e.g. tidal volume. With M and K known, every pair of RIPab and RIPrc are converted to a calibrated volume.
  • 11. History • NIMS • September 1991 introduces Respitrace Plus Respitrace Plus monitors breathing pattern and the electrocardiogram. It incorporates NIMS' patented Respitrace technology for assessment of respiratory frequency, changes of tidal volume, labored breathing and detection of central and obstructive apneas. Respitrace is the only commercially available technology that by itself is capable of monitoring these parameters © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 12. History • NIMS – SensorMedics Agreement • August 2 1994 • Respitrace PT2 • Respitrace Plus • Respitrace Cardio • Respibands © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 13. History • SensorMedics / VIASYS – April 1999 – Qualitative Diagnostic Calibration • 5 minutes Normal Resting Breathing – Calibrated SUM channel – FVL with RespiEvents Software – dVt Channel (Derived Flow) in 2002 – FVL integrated into Somnostar in 2002 © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 14. History • Compumedics • David Burton • Jiang Hong Tan • Patent # 6142953 November 2000 A device for reliably and non-invasively measuring respiration rates and effort by encircling the patient's chest with a device having a large section of inelastic belt attached to a small section of elastic material. The elastic material having two magnetic tapes with wire windings thereon proximate each other with an insulation material therebetween. The wire windings are electrically connected to each other. The magnetic tapes have opposite ends attached to the elastic material such that when the elastic material expands and contracts the wire windings move relative to each. A toroidal transformer is connected to the wire windings. When a carrier signal is introduced to the transformer and the magnetic tapes move relative to each other on the elastic material when the patient breathes a mutual inductance in the wire windings modulates the carrier signal and thus measures the expansion and contraction of the patient's chest which is directly related to the patient's respiration rate. The electronics connected to the device for monitoring respiration also measures belt shifting for diameter changes during monitoring by measuring the central amplitude during a breath cycle and comparing the initial belt diameter conditions to later conditions. The electronics can then compensate for amplitude variations in the signal caused by belt shifting which may be confused with shallower breathing in uncompensated devices. © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 15. History • Compumedics 2000 • • • • • • • • • • • • • • • • Inductive plethysmography technology Linear response to changes in effort Balanced SUM channel output Continuous, automatic channel balancing Operates with any PSG amplifier system 800 hours of operation from a small low-cost battery Long lasting, reusable sensor bands Cost effective and easy to use © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 16. History • Embla 2005 • • • • • • • • • • • • • • • XFlow™ is a semi-quantitative measure of inspiratory and expiratory flow, providing a complementary flow signal for studies without airflow sensors. X-flow is a reliable backup and great tool for titrations. • XSum™ is the summation of the abdominal and thoracic signals providing a semi-quantitative measurement of lung volume. • RMI™ (Respiratory Mechanics Instability) is a proprietary algorithm that assesses the severity of Sleep Disordered Breathing by analyzing the phase relationship between the abdomen and thorax. • Phase Analysis displays (in degrees) the phase relationship between the abdomen and the thorax for evaluation and analysis of paradoxical breathing. © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 17. History • Pro Tech June 2005 • zRIP – Compatible with all PSG systems – Washable belts – Non-calibrating SUM channel © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 18. History • Braebon 2006 • Q-RIP – Compatible with all PSG systems – Non-calibrating SUM channel © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 19. History • Sleepmate 2007 • RIPmate – Compatible with all PSG systems – Non-calibrating SUM channel The RIPmate system is designed with a washable one-size-fits-all belt and buckle that is comfortable and stays in place. The RIPmate Inductance Processor module plugs directly into the AC input of any headbox with no additional software needed. The system provides a reliable effort signal that eliminates the problems of effort signal loss and false paradoxical signals. © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 20. Comparison Piezo Belts – Poor QUALITATIVE grading of waveform • NOT Quantitative – False Paradox due to low signal – Must be readjusted throughout night – Loss of signal due to position shift © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 21. Comparison Non Calibrated RIP •False paradox eliminated (if reference and signal inputs must be connected with the same polarity). •Excellent signal quality •Small interface device (usually battery operated) •Sum channel not equal to true RC + ABD volume change © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 22. Comparison Calibrated RIP • False paradox eliminated •Excellent signal quality •Larger driver/interface device (usually AC operated) •Sum channel equal to true RC + ABD volume change •dVt •FVL •Konno Mead Loops • QUANTITATIVE © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 23. Device Comparison © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 24. Obstructive Apnea No Flow Paradoxical Effort © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 25. Central Apnea No Flow! No Volume! © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved. No Patient Effort
  • 26. Hypopneas - Non Calibrated RIP © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 27. Hypopneas – Calibrated RIP with FVL © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 28. Hypopnea • Take the guesswork out of Hypopneas! • Quantify the difference of percentage of breaths against the Baseline Breath © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 29. Inspiratory Flow Limitation - UARS • Flattening on the Inspiratory Side of the Flow Volume Loop vs. • Chest and Abdomen out of Phase © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 30. Inspiratory Flow Limitation UARS Flattening of dVt Channel Flattening of Chest Signal Increased I:E Ratio © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved. Flattening of Inspiratory Curve
  • 31. CPAP TITRATION The first step to compliance is proper Titration Eliminate all obstructive and events • Gross titration by stepwise increases in PAP until no events are observed via Thermocouple/Nasal Pressure and effort belts. Elimination of UARS • Fine titration of stepwise increases in PAP until Airway is splinted open observed via Flow Volume Loops or Esophageal Pressure. Elimination of Central Events caused by over titration • Observe FVLs for hyperinflation Elimination of increased WOB / increased Expiratory Resistance • Treat Flattening of expiratory curve with Pressure Release © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 32. How can cRIP Help ? Flow Volume Loops – Breath used as the “Signature Breath” • Select a Baseline Breath at Sleep Onset – Compare breaths to the Baseline Breath • CPAP Titrations – Titrate sleep patients back to their “Signature Breath • UARS Visualize Inspiratory Flow Limitation1 • Hypopnea Events – Show a difference or a percentage as compared to the Baseline Breath – Differentiate between Mixed, Obstructive and Central Hypopneas2 1 Daniel Loube, MD, FCCP, Teotimo Andrada, MS. Pulmonary/Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC, USA COMPARISON OF RESPIRATORY INDUCTANCE PLETHYSMOGRAPHY AND ESOPHAGEAL PRESSURE MONITORING IN THE DETECTION OF UPPERAIRWAY RESISTANCE SYNDROME 2 Classification of a hypopnea as obstructive, central or mixed should not be performed without a quantitative assessment of ventilatory effort (esophageal manometry, calibrated respiratory inductance plethysmography, or diaphragmatic/intercostal EMG) ASSM Manual for the Scoring of Sleep and Associated Events © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 33. How can cRIP Help ? Konno Mead Loops – Work of Breathing • Visualize accessory muscle use vs. diaphragmatic effort • Monitor Increased Expiratory Resistance during titrations – Chest/Abdominal Asynchrony • Phase Angle shift – Central vs. Obstructive events • True Paradox © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 34. Konno Mead Loop Breakdown R i b C a g e Expiration Inspiration Abdomen © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 35. How can cRIP Help ? Breath by Breath Tabular View – Monitor I:E Ratios Inspiratory/Expiratory times • Inverse I:E ratios indicate increased Inspiratory Resistance – Pif-Mif Peak Inspiratory Flow/Mean Inspiratory Flow • Peak flow greater than the mean flow implies a work rate greater than a constant flow1. <1.5 = inspiratory flow limitation1 – Selection of multiple breaths for comparison and printing 1. Lafortuna CL, Minetti AE, Mognoni P. Inspiratory pattern in humans. J Appl Physiol 1984;57:1111-1119. © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 36. PAP Titration with cRIP Select a reproducible breath Normal FVL © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 37. PAP Titration with cRIP Titrate to Eliminate Events © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 38. PAP Titration with cRIP Eliminate UARS Titrate PAP to Open Loop Inspiratory Resistance (UARS) Inverse I:E ratio Increased WOB © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 39. PAP Titration with cRIP • Titrate Inspiratory and Expiratory curves separately to Baseline Breath with Bi-Level • Optimize Expiratory Pressure Release to decreased expiratory resistance using FVLs and decrease WOB with Konno Mead Loops © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 40. PAP Titration with cRIP Titrate Bi-Level to Eliminate Hypoventilation Titrate EPAP to Eliminate Events Titrate IPAP to increase Vt © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 41. PAP Titration with cRIP Eliminate Expiratory Resistance Titrate Pressure Release to Open Loop Expiratory Resistance Increased WOB © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 42. PAP Titration with cRIP Eliminate Central Apneas Caused by Over Titration Reduce Pressure to Decrease Vt Central Apneas © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 43. Successful Titration with cRIP Elimination of Events Elimination of UARS Titrated Loops = Baseline Loop No Hyperinflation WOB returns to Baseline Level Successful Titration = Better Compliance = Satisfied Customer © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.
  • 44. Summary • Long History of Research and Development • Validated technique • Available calibrated and uncalibrated • Accurate event detection • A better way to measure Effort • Enhanced software packages with FVL and Konno Mead Loops • A better tool for titration © 2009 CareFusion Corporation or one of its subsidiaries. All rights reserved.