This document discusses a new business opportunity in the skincare industry enabled by changing market conditions. The $2.5 billion anti-aging skincare market is growing significantly. A new direct sales model is presented that offers clinically proven skincare products developed by renowned dermatologists, a established brand presence, and business support programs. This opportunity provides entrepreneurs a low cost of entry and high profit potential by leveraging their personal networks through a direct sales model.
We deliver self funding services in the areas of cost recovery, contract compliance, review and negotiation, and billing optimization for voice, data and wireless communications services.
Cómo las Redes Sociales y Tecnologías Derivadas Impactan en los Procesos In...Antoine GRILLON
¿Qué hacer cuando dejamos de hablar de Likes / Seguidores, Vistas / etc…? ¿Son realmente nuevas las redes sociales y el concepto de Economía Colaborativa? Cuándo hablamos de redes sociales ¿nos referimos a relaciones públicas, branding, servicio al cliente, etc. o a algo más profundo que tiene que analizarse desde un punto de vista estratégico? ¿Cómo aplicar metodologías para impactar lo que realmente importa en una empresa, los resultados financieros?
The Anti-Age Market is $2.5 Billion and growing. See what is possible when you leverage two of the biggest names in skincare, an innovative business model and clinically proven anti-aging products. http://juliebierster.myrandf.com
We deliver self funding services in the areas of cost recovery, contract compliance, review and negotiation, and billing optimization for voice, data and wireless communications services.
Cómo las Redes Sociales y Tecnologías Derivadas Impactan en los Procesos In...Antoine GRILLON
¿Qué hacer cuando dejamos de hablar de Likes / Seguidores, Vistas / etc…? ¿Son realmente nuevas las redes sociales y el concepto de Economía Colaborativa? Cuándo hablamos de redes sociales ¿nos referimos a relaciones públicas, branding, servicio al cliente, etc. o a algo más profundo que tiene que analizarse desde un punto de vista estratégico? ¿Cómo aplicar metodologías para impactar lo que realmente importa en una empresa, los resultados financieros?
The Anti-Age Market is $2.5 Billion and growing. See what is possible when you leverage two of the biggest names in skincare, an innovative business model and clinically proven anti-aging products. http://juliebierster.myrandf.com
Redefining Business Ownership
This is a particularly compelling time to be part of Rodan + Fields as convergence of important trends is creating new business opportunities and making traditional business models obsolete.
• $2.5 Billion anti-aging skincare projected to double in next five years*
• Rodan + Fields creating transformational product systems for aging skin
• Rise of social economy shifts power from corporations to individuals
• Business model and compensation plan provides substantial income potential with minimal upstart costs
The power of the Rodan + Fields Business System is already evident. In 2007, Rodan + Fields was a leading clinical skincare brand in high end department stores. Since withdrawing from department stores and launching the direct selling program, numerous Rodan + Fields independent business owners are experiencing the income associated with sales volume that far exceeds what leading department store chains were able to achieve.
FOR MORE INFORMATION, CONTACT CRYSTAL F. ROWLEY AT HTTP://CROWLEY.MYRANDF.BIZ
*Euromonitor and Global Industry Analyst
Dr. Rodan and Dr. Fields revolutionized the acne industry with ProActiv. Now we are a team revolutionizing the ANTI-AGE industry with a CLINICALLY PROVEN ANTI-AGE line. We have a skin care line for EVERYONE! Have freckles, sun damage, dark spots, blotchy skin, or uneven skin tone? Try the REVERSE regimen. A Specially formulated regimen with MULTI-medication approach. Eczema, Melasma, Psoriasis, Rosacea, Seborrheic dermatitis and Sensitive skin are all conditions that leave intrusive visible hyperpigmentation marks on the skin. Our SOOTHE regimen produces VISIBLE results. Still experiencing acne breakouts in your 20's, 30's, or 40's? UNBLEMISH is a successful line for all ages. It's about using the right combination of medications, in the right order, with the right delivery vehicle to penetrate deeper into the skin. The Rodan+Fields business model has a high potential for residual income. I would be honored if you joined me on the road to early retirement. Become an Independent Consultant today. Visit my website www.DrDirck.myrandf.biz for details. Alternatively, if you just want to try our products, take my perskinality quiz to determine which product is right for you, www.DrDirck.myrandf.com. Get the Skinny on your Skin! Skin is a beautiful thing, wear it well.
Rodan and Fields - Presentation to Prospective InvestorsJCBierster
Rodan and Fields has developed successful breakthrough solutions for diverse types of skin needs. This solution, and the business model offered for entrepreneurs, has created a transformational opportunity for independent business ownership. http://juliebierster.myrandf.biz
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2. Partnering with Entrepreneurs to
Deliver Breakthrough Skincare Solutions
and Substantial Income Potential
CONFIDENTIAL [2]
3. Convergence is Creating New Business Opportunities
+$2.5 Billion Spent
Breakthroughs
Annually on
In Skincare
Anti-aging
TRADITIONAL
Business Models are
OBSOLETE
Shift in
Rise of the
Power from
Social
Corporations to
Economy
Individuals
CONFIDENTIAL [3]
4. The Right Business Model,
at the Right Time, in the Right Market
Products Presence
Clinically Proven Solutions Trusted Dermatologists,
That Deliver Results Established Brand
Support Direct Sales Model
to Monetize with Low Cost
the Value of Entry,
of Your Network High Profit Potential
Programs Profit
CONFIDENTIAL [4]
6. An Opportunity to Participate
in a Billion Dollar, Growing Market
U.S. Spending on Anti-Aging Skincare
$5.0 Billion
Significant
Market Expansion
$2.5 Billion
2009 2015
Source: Euromonitor, Global Industry Analyst
CONFIDENTIAL [6]
7. We’re All Aging, All the Time
Skincare Is the #1 Defense
Against Aging
84% of Women Feel Pressure to
Look Younger
Many Consumers Are Dissatisfied
with Their Current Products
84% of Women in Their 20s
Are Concerned About Aging
100% of Women Want to Look
Younger than their Years
Source: Rodan + Fields Beauty: The Impact of Aging Study, 2010
CONFIDENTIAL [7]
8. A Synergistic Approach to Skincare
AMP-MD Delivery System
ANTI-AGE Regimen
Patent Pending System
Ensures the Delivery of
Comprehensive
Regimen Supports Key Anti-Aging
the Natural Ingredients into Upper
Processes that Layers of the Skin
Strengthen the
Skin’s Structure
Designed for the Prevention and Correction of the Visible Signs of Aging
Combines the Right Ingredients, in the Right Formulations, in the Right Order
No Prescription Required, 60-Day Satisfaction Guarantee
CONFIDENTIAL [8]
9. Clinically Proven Benefits
Average Improvement Before Treatment*
54% Radiance
51% Even Skin Tone
48% Fine Lines
46% Wrinkles
43% Visible Pores
43% Brown Spots
36% Softness
% of Participants Experiencing an Improvement After Treatment*
100% Skin Texture
89% Fine Lines
84% Overall
84% Moisturization
68% Firmness
53% Even Skin Tone
36% Pore Size
Source: Independent 9 Week Clinical Trial , Results May Vary, *Skin Replicas of Crows Feet CONFIDENTIAL [9]
12. Trusted Dermatologists
Two of the Most Recognized
Names in Skincare
“ A dermatological dream team. ”
— Women’s Health
Successful Entrepreneurs
Trained at Stanford University School of
Medicine
Creators of Proactiv®, the World’s Most
Successful Acne Treatment
Redefined the Market for Acne Skincare,
Redefining Anti-aging Skincare
CONFIDENTIAL [ 12 ]
13. Established Brand with Significant Media Coverage
Print Television Web
More Media Coverage
than Any Other Direct Selling Company
Source: Meltwater News, US Coverage Only; Excludes Avon due to Extensive Paid Advertising CONFIDENTIAL [ 13 ]
15. Our Direct Sales Model
Focuses on Where the Power Resides
2010
Direct Sales
the Rising Star in Direct Sales
2007
Retail Sales
A Leading Clinical Skincare Line in Prestige Department Stores
CONFIDENTIAL [ 15 ]
16. A Unique Model
Leverage Your Network
Share the Product
Scale Efficiently and Quickly
No Product Inventory
LOW Cost of Entry HIGH Profit Potential
Return on Your Investment
in the First Month
Long-Term Residual Income
Unlimited Earning Potential
CONFIDENTIAL [ 16 ]
17. Leverage the Exponential Value of Your Network
you
Multiple “Generations” of Connections Drives Incremental Opportunities
Technology Enables Leverage, Speed and Duplication
Multiple Sources of Income: Sales and Commissions
CONFIDENTIAL [ 17 ]
19. Proven, Turnkey Business Support
Customer Care Assessment Tools Training
Email and Phone Sophisticated Ongoing Skincare
Access to Registered “Prescription” Tools and Business
Nurses with and Guidelines for Education From
Dermatology Determining Leaders in
Experience Skincare Needs the Field
Business System
Comprehensive Online and Offline Tools
to Run Your Business Anytime, Anywhere
CONFIDENTIAL [ 19 ]
20. A Business Opportunity
for Entrepreneurs with Diverse Backgrounds
Stay-at-Home Mother and Wife of Former Major League Baseball Player
Country Music Writer | Corporate Chief Financial Officer | Aesthetician
Elementary School Teacher | Luxury Real Estate Agent | Attorney
Home Schooling Mom| Pharmaceutical Sales Representative
Beauty Industry Marketing Executive | General Contractor / Builder
Former Professional Figure Skater | Public Relations Executive | Artist and
Entrepreneur | Commercial Real Estate Broker | Corporate Sales Trainer
CONFIDENTIAL [ 20 ]
21. Start Your Own Business Today
It Takes Minutes to Get Started
Complete Online Application
Choose Your Product
IMMEDIATE…
… Creation of Personalized Storefront
… Access to Business Tools
… Delivery of Display Products and Materials
CONFIDENTIAL [ 21 ]
22. The Right Business Model,
at the Right Time, in the Right Market
Products Presence
Programs Profit
CONFIDENTIAL [ 22 ]
![Redefining Business Ownership
Changing Skin. Changing Lives.
CONFIDENTIAL [1]](https://image.slidesharecdn.com/businesssystempresentation10-4-10-110719165344-phpapp01/85/Business-system-presentation_10-4-10-1-320.jpg)
![Partnering with Entrepreneurs to
Deliver Breakthrough Skincare Solutions
and Substantial Income Potential
CONFIDENTIAL [2]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)